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The map label for this gene is pfbA [H]

Identifier: 15927491

GI number: 15927491

Start: 1985277

End: 1986374

Strand: Reverse

Name: pfbA [H]

Synonym: SA1733

Alternate gene names: 15927491

Gene position: 1986374-1985277 (Counterclockwise)

Preceding gene: 15927495

Following gene: 15927490

Centisome position: 70.57

GC content: 32.88

Gene sequence:

>1098_bases
ATGTATATCAATATGAAAGATTATGGGTTAACAGGCATAAACAAAACTAAAGATACTCGAGCAATACAACGTGCGTTAAA
TCGTGGAAGATGTAAACCAACGACAGTTTATATACCGAAAGGGACGTATGATATTTGCAAACCATTAACGATATATGGCA
ATACAACACTTTTGTTAGATAATGAAACTATTTTACGCCGATGTCATTCTGGTCCTTTATTAAAAAATGGTCATCGCTTT
GGTTTTTATCGTGGTTATAATGGACACAGTCATATTCATATTAAAGGCGGCAAGTTTGATATGAATGGTGTATCGTATCC
TTATAACAATACAGCTATGTGCATTGGGCATGCTGAAGATATTCAATTAATAGGTGTGACCATTAAGAATGTAGTGAGTG
GTCATGCAATTGATGCTTGTGGGATTAACGGACTCTATATTAAAAGCTGTTCATTTGAAGGATTCATAGACTATAGTGGC
GAACGCTTTTATTCTGAAGCAATACAATTAGACATTCAAGTACCTGGTGCTTTTCCAAAATTCGGAACGACAGATGGTAC
GATAACGAAAAATGTCGTTATCGAAGATTGTTATTTTGGACCTTCAGAATTGCCCGAAATGGGAAGTTGGAATCGTGCTA
TTGGCTCACATGCAAGTAGACATAATCGTTACTATGAGAATATTCATATTAGAAATAATATATTTGAAGATATACAAGGT
TATGCATTAACTCCCTTGAAGTATAAAGATGCTTTCATTATTAATAATAAGTTTATTAACTGTGAGGGTGGTATTAGATA
TTTAGGAGTTAGAGATGGTAAAAATGCAGCAGATGTGATGACAGGAAAAGACTTAGGTTCCCAAGCAGGCATAAATATGA
ATATAATTGGAAATGAATTTAAAGGATCAATGTCTAAAGATGCGATACATGTACGTAATTATAATAATGTTAAACATAAA
GATGTATTAATCGTTGGGAATACATTCAATAATTCGACTCAATCAATTCATTTAGAAGATATTGATACAGTGTTTTTAAG
TCCTGTTGAAGCGGGTATTCAAGTTACTACAATCAATATAGATGAAATAAAAAAGTAA

Upstream 100 bases:

>100_bases
CGAGATTTATGACTATCTGCTAAATCAACCTAACACGATTATAATTTGAATAATTGGTTAATATATGAGTAATTAGAAAA
TAGACAAAGGATGACGATTT

Downstream 100 bases:

>100_bases
AAAGTTTCGCATGACATTAGGATTAAGAATAGTAGATAATTTTTGAAAGCGCATTCATAAAACGGTATAAATATGCTATA
ATAAACCCAATTATCTGATA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MYINMKDYGLTGINKTKDTRAIQRALNRGRCKPTTVYIPKGTYDICKPLTIYGNTTLLLDNETILRRCHSGPLLKNGHRF
GFYRGYNGHSHIHIKGGKFDMNGVSYPYNNTAMCIGHAEDIQLIGVTIKNVVSGHAIDACGINGLYIKSCSFEGFIDYSG
ERFYSEAIQLDIQVPGAFPKFGTTDGTITKNVVIEDCYFGPSELPEMGSWNRAIGSHASRHNRYYENIHIRNNIFEDIQG
YALTPLKYKDAFIINNKFINCEGGIRYLGVRDGKNAADVMTGKDLGSQAGINMNIIGNEFKGSMSKDAIHVRNYNNVKHK
DVLIVGNTFNNSTQSIHLEDIDTVFLSPVEAGIQVTTINIDEIKK

Sequences:

>Translated_365_residues
MYINMKDYGLTGINKTKDTRAIQRALNRGRCKPTTVYIPKGTYDICKPLTIYGNTTLLLDNETILRRCHSGPLLKNGHRF
GFYRGYNGHSHIHIKGGKFDMNGVSYPYNNTAMCIGHAEDIQLIGVTIKNVVSGHAIDACGINGLYIKSCSFEGFIDYSG
ERFYSEAIQLDIQVPGAFPKFGTTDGTITKNVVIEDCYFGPSELPEMGSWNRAIGSHASRHNRYYENIHIRNNIFEDIQG
YALTPLKYKDAFIINNKFINCEGGIRYLGVRDGKNAADVMTGKDLGSQAGINMNIIGNEFKGSMSKDAIHVRNYNNVKHK
DVLIVGNTFNNSTQSIHLEDIDTVFLSPVEAGIQVTTINIDEIKK
>Mature_365_residues
MYINMKDYGLTGINKTKDTRAIQRALNRGRCKPTTVYIPKGTYDICKPLTIYGNTTLLLDNETILRRCHSGPLLKNGHRF
GFYRGYNGHSHIHIKGGKFDMNGVSYPYNNTAMCIGHAEDIQLIGVTIKNVVSGHAIDACGINGLYIKSCSFEGFIDYSG
ERFYSEAIQLDIQVPGAFPKFGTTDGTITKNVVIEDCYFGPSELPEMGSWNRAIGSHASRHNRYYENIHIRNNIFEDIQG
YALTPLKYKDAFIINNKFINCEGGIRYLGVRDGKNAADVMTGKDLGSQAGINMNIIGNEFKGSMSKDAIHVRNYNNVKHK
DVLIVGNTFNNSTQSIHLEDIDTVFLSPVEAGIQVTTINIDEIKK

Specific function: Acts as a fibronectin-dependent adhesin and invasin. Binds host (in this case human) fibronectin, plasmin, plasminogen, and human serum albumin. Where the bacteria adhere to human cells there is major recruitment of microvilli which seem to fuse to cover

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 5 PbH1 repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005877
- InterPro:   IPR006626
- InterPro:   IPR012334
- InterPro:   IPR011050 [H]

Pfam domain/function: PF04650 YSIRK_signal [H]

EC number: NA

Molecular weight: Translated: 40701; Mature: 40701

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYINMKDYGLTGINKTKDTRAIQRALNRGRCKPTTVYIPKGTYDICKPLTIYGNTTLLLD
CEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHCCCEEEECCEEEEEC
NETILRRCHSGPLLKNGHRFGFYRGYNGHSHIHIKGGKFDMNGVSYPYNNTAMCIGHAED
CHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEEEECCEEECCCCCCCCCCEEEEEECCCC
IQLIGVTIKNVVSGHAIDACGINGLYIKSCSFEGFIDYSGERFYSEAIQLDIQVPGAFPK
EEEEEEEHHHHHCCCCEEECCCCCEEEEECCCCEEEECCCCCEEEEEEEEEEECCCCCCC
FGTTDGTITKNVVIEDCYFGPSELPEMGSWNRAIGSHASRHNRYYENIHIRNNIFEDIQG
CCCCCCCEEEEEEEEECCCCHHHCCCCCCCHHHHHCHHHHCCCEEEEEEECCCHHHHCCC
YALTPLKYKDAFIINNKFINCEGGIRYLGVRDGKNAADVMTGKDLGSQAGINMNIIGNEF
CEECCEEECCEEEEECEEEECCCCEEEEEEECCCCHHHEEECCCCCCCCCEEEEEECCCC
KGSMSKDAIHVRNYNNVKHKDVLIVGNTFNNSTQSIHLEDIDTVFLSPVEAGIQVTTINI
CCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCEEEEECCCEEEECHHHCCEEEEEEEH
DEIKK
HHHCC
>Mature Secondary Structure
MYINMKDYGLTGINKTKDTRAIQRALNRGRCKPTTVYIPKGTYDICKPLTIYGNTTLLLD
CEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHCCCEEEECCEEEEEC
NETILRRCHSGPLLKNGHRFGFYRGYNGHSHIHIKGGKFDMNGVSYPYNNTAMCIGHAED
CHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEEEECCEEECCCCCCCCCCEEEEEECCCC
IQLIGVTIKNVVSGHAIDACGINGLYIKSCSFEGFIDYSGERFYSEAIQLDIQVPGAFPK
EEEEEEEHHHHHCCCCEEECCCCCEEEEECCCCEEEECCCCCEEEEEEEEEEECCCCCCC
FGTTDGTITKNVVIEDCYFGPSELPEMGSWNRAIGSHASRHNRYYENIHIRNNIFEDIQG
CCCCCCCEEEEEEEEECCCCHHHCCCCCCCHHHHHCHHHHCCCEEEEEEECCCHHHHCCC
YALTPLKYKDAFIINNKFINCEGGIRYLGVRDGKNAADVMTGKDLGSQAGINMNIIGNEF
CEECCEEECCEEEEECEEEECCCCEEEEEEECCCCHHHEEECCCCCCCCCEEEEEECCCC
KGSMSKDAIHVRNYNNVKHKDVLIVGNTFNNSTQSIHLEDIDTVFLSPVEAGIQVTTINI
CCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCEEEEECCCEEEECHHHCCEEEEEEEH
DEIKK
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11544234 [H]