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The map label for this gene is asnC

Identifier: 15927035

GI number: 15927035

Start: 1491414

End: 1492706

Strand: Reverse

Name: asnC

Synonym: SA1287

Alternate gene names: 15927035

Gene position: 1492706-1491414 (Counterclockwise)

Preceding gene: 15927036

Following gene: 15927034

Centisome position: 53.03

GC content: 35.58

Gene sequence:

>1293_bases
ATGAAAACAACGATTAAACAAGCGAAAGATCATTTAAACCAAGACGTTACAATTGGTGCTTGGTTAACAAATAAACGTTC
AAGTGGTAAAATCGCCTTTTTACAATTACGTGATGGAACAGGCTTTATGCAAGGCGTAGTAGTTAAATCAGAAGTTGATG
AAGAGGTATTCAAACTTGCGAAAGAAATTGCTCAAGAATCATCTCTATACGTTACAGGCACAATTACAGAAGATAATCGT
TCTGACTTAGGATACGAAATGCAAGTGAAATCAATTGAAGTTATTTCAGAAGCGCATGACTATCCGATTACACCTAAAAA
TCATGGTACAGAATTCTTAATGGATCACCGTCATTTATGGTTACGTTCTAAAAAACAACATGCTGTAATGAAAATTAGAA
ATGAAGTTATTCGTGCAACGTATGAATTTTTCAACAAAGATGGATTTACAAAGGTTGATCCACCAATTTTGACAGCAAGT
GCACCAGAAGGTACAAGTGAATTATTCCATACTAAATACTTTGATCAAGATGCGTTTTTATCTCAAAGTGGTCAGTTATA
CTTAGAAGCTGCAGCAATGGCACACGGAAAAGTATTTTCATTTGGTCCAACTTTCAGAGCTGAAAAATCAAAAACACGTA
GACACTTGATCGAGTTCTGGATGATTGAAGGGGAAATGGCTTTCACAAATCATGCTGAAAGTTTAGAAATTCAAGAACAA
TATGTAACACATGTAGTAAAATCAGTTTTAGAAAATTGTAAACTAGAGTTGAAAATTTTAGAGCGTGATACATCAAAACT
TGAAAAAGTTGCGACACCATTCCCTAGAATTTCATATGATGATGCAATTGAATTCTTAAAAGCAGAAGGCTTTGATGATA
TTGAATGGGGTGAAGATTTTGGTGCGCCACATGAAACTGCCATTGCTAATCATTATGATTTACCGGTGTTTATTACTAAT
TATCCAACTAAAATTAAGCCTTTCTATATGCAACCAAATCCTGAGAATGAAGAAACTGTCTTATGTGCAGACTTAATTGC
ACCTGAAGGATACGGTGAAATTATCGGTGGATCTGAACGTGTGGATGACTTAGAATTGTTAGAACAACGCGTTAAAGAAC
ATGGATTAGACGAAGAAGCATATAGTTACTACTTAGACTTACGTCGTTATGGTAGTGTGCCACACTGTGGATTTGGTTTA
GGTTTAGAGCGCACAGTAGCATGGATTTCTGGTGTTGAACACGTTCGTGAAACTGCGCCATTCCCAAGATTATTAAACCG
TTTATATCCATAA

Upstream 100 bases:

>100_bases
CATTTACACGTTATCTTTTAGTCTAGTTCTAGAACTTGAAAGCGGATTTTGTTAAAATGAATGAGTATTGTATAACGAAA
AAATAAATAGGAGAATGGTT

Downstream 100 bases:

>100_bases
GTTTTAGGATCGTTACTTAAAATTTATATTATGATAATAAAAAGAATCGTCCAGCCTATATTAATAGCTGGGCGATTTAT
GCTTGCAAAATGAAGATTGA

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MKTTIKQAKDHLNQDVTIGAWLTNKRSSGKIAFLQLRDGTGFMQGVVVKSEVDEEVFKLAKEIAQESSLYVTGTITEDNR
SDLGYEMQVKSIEVISEAHDYPITPKNHGTEFLMDHRHLWLRSKKQHAVMKIRNEVIRATYEFFNKDGFTKVDPPILTAS
APEGTSELFHTKYFDQDAFLSQSGQLYLEAAAMAHGKVFSFGPTFRAEKSKTRRHLIEFWMIEGEMAFTNHAESLEIQEQ
YVTHVVKSVLENCKLELKILERDTSKLEKVATPFPRISYDDAIEFLKAEGFDDIEWGEDFGAPHETAIANHYDLPVFITN
YPTKIKPFYMQPNPENEETVLCADLIAPEGYGEIIGGSERVDDLELLEQRVKEHGLDEEAYSYYLDLRRYGSVPHCGFGL
GLERTVAWISGVEHVRETAPFPRLLNRLYP

Sequences:

>Translated_430_residues
MKTTIKQAKDHLNQDVTIGAWLTNKRSSGKIAFLQLRDGTGFMQGVVVKSEVDEEVFKLAKEIAQESSLYVTGTITEDNR
SDLGYEMQVKSIEVISEAHDYPITPKNHGTEFLMDHRHLWLRSKKQHAVMKIRNEVIRATYEFFNKDGFTKVDPPILTAS
APEGTSELFHTKYFDQDAFLSQSGQLYLEAAAMAHGKVFSFGPTFRAEKSKTRRHLIEFWMIEGEMAFTNHAESLEIQEQ
YVTHVVKSVLENCKLELKILERDTSKLEKVATPFPRISYDDAIEFLKAEGFDDIEWGEDFGAPHETAIANHYDLPVFITN
YPTKIKPFYMQPNPENEETVLCADLIAPEGYGEIIGGSERVDDLELLEQRVKEHGLDEEAYSYYLDLRRYGSVPHCGFGL
GLERTVAWISGVEHVRETAPFPRLLNRLYP
>Mature_430_residues
MKTTIKQAKDHLNQDVTIGAWLTNKRSSGKIAFLQLRDGTGFMQGVVVKSEVDEEVFKLAKEIAQESSLYVTGTITEDNR
SDLGYEMQVKSIEVISEAHDYPITPKNHGTEFLMDHRHLWLRSKKQHAVMKIRNEVIRATYEFFNKDGFTKVDPPILTAS
APEGTSELFHTKYFDQDAFLSQSGQLYLEAAAMAHGKVFSFGPTFRAEKSKTRRHLIEFWMIEGEMAFTNHAESLEIQEQ
YVTHVVKSVLENCKLELKILERDTSKLEKVATPFPRISYDDAIEFLKAEGFDDIEWGEDFGAPHETAIANHYDLPVFITN
YPTKIKPFYMQPNPENEETVLCADLIAPEGYGEIIGGSERVDDLELLEQRVKEHGLDEEAYSYYLDLRRYGSVPHCGFGL
GLERTVAWISGVEHVRETAPFPRLLNRLYP

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI226491502, Length=444, Percent_Identity=35.3603603603604, Blast_Score=262, Evalue=5e-70,
Organism=Homo sapiens, GI4758762, Length=432, Percent_Identity=33.3333333333333, Blast_Score=230, Evalue=2e-60,
Organism=Homo sapiens, GI45439306, Length=451, Percent_Identity=31.2638580931264, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI40789249, Length=236, Percent_Identity=28.8135593220339, Blast_Score=76, Evalue=7e-14,
Organism=Escherichia coli, GI1787161, Length=457, Percent_Identity=37.636761487965, Blast_Score=290, Evalue=1e-79,
Organism=Escherichia coli, GI1790571, Length=464, Percent_Identity=23.9224137931034, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788173, Length=246, Percent_Identity=26.8292682926829, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1789256, Length=458, Percent_Identity=23.3624454148472, Blast_Score=89, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71984122, Length=440, Percent_Identity=34.5454545454545, Blast_Score=250, Evalue=8e-67,
Organism=Caenorhabditis elegans, GI17556372, Length=411, Percent_Identity=30.9002433090024, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17551876, Length=460, Percent_Identity=28.2608695652174, Blast_Score=164, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI32566633, Length=286, Percent_Identity=26.2237762237762, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6321807, Length=443, Percent_Identity=33.4085778781038, Blast_Score=257, Evalue=3e-69,
Organism=Saccharomyces cerevisiae, GI6319872, Length=469, Percent_Identity=32.6226012793177, Blast_Score=230, Evalue=3e-61,
Organism=Saccharomyces cerevisiae, GI6323011, Length=464, Percent_Identity=28.8793103448276, Blast_Score=162, Evalue=7e-41,
Organism=Saccharomyces cerevisiae, GI6325153, Length=257, Percent_Identity=28.4046692607004, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19921528, Length=442, Percent_Identity=34.841628959276, Blast_Score=238, Evalue=8e-63,
Organism=Drosophila melanogaster, GI19922416, Length=444, Percent_Identity=32.2072072072072, Blast_Score=215, Evalue=5e-56,
Organism=Drosophila melanogaster, GI17136276, Length=438, Percent_Identity=29.9086757990868, Blast_Score=174, Evalue=8e-44,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SYN_STAA1 (A7X2E9)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442032.1
- ProteinModelPortal:   A7X2E9
- SMR:   A7X2E9
- STRING:   A7X2E9
- EnsemblBacteria:   EBSTAT00000004333
- GeneID:   5561291
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1442
- eggNOG:   COG0017
- GeneTree:   EBGT00050000023877
- HOGENOM:   HBG745843
- OMA:   EPEMAFC
- ProtClustDB:   PRK03932
- BioCyc:   SAUR418127:SAHV_1442-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00534
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00457

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.22

Molecular weight: Translated: 49128; Mature: 49128

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTTIKQAKDHLNQDVTIGAWLTNKRSSGKIAFLQLRDGTGFMQGVVVKSEVDEEVFKLA
CCCHHHHHHHHCCCCEEEEEEEECCCCCCCEEEEEEECCCCCHHHEEEHHHHHHHHHHHH
KEIAQESSLYVTGTITEDNRSDLGYEMQVKSIEVISEAHDYPITPKNHGTEFLMDHRHLW
HHHHHCCCEEEEEEEECCCCCCCCEEEEHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
LRSKKQHAVMKIRNEVIRATYEFFNKDGFTKVDPPILTASAPEGTSELFHTKYFDQDAFL
HHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCHHHHHHHHHCCCHHHH
SQSGQLYLEAAAMAHGKVFSFGPTFRAEKSKTRRHLIEFWMIEGEMAFTNHAESLEIQEQ
CCCCCEEEEEEHHHCCCEEECCCCCCCHHHHHHHHHHHHHEECCCEEECCCCCHHHHHHH
YVTHVVKSVLENCKLELKILERDTSKLEKVATPFPRISYDDAIEFLKAEGFDDIEWGEDF
HHHHHHHHHHHCCCEEEEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCHHC
GAPHETAIANHYDLPVFITNYPTKIKPFYMQPNPENEETVLCADLIAPEGYGEIIGGSER
CCCCHHHHCCCCCCCEEEECCCCCCEEEEECCCCCCCCEEEEEHHHCCCCCCCCCCCCCC
VDDLELLEQRVKEHGLDEEAYSYYLDLRRYGSVPHCGFGLGLERTVAWISGVEHVRETAP
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
FPRLLNRLYP
HHHHHHHHCC
>Mature Secondary Structure
MKTTIKQAKDHLNQDVTIGAWLTNKRSSGKIAFLQLRDGTGFMQGVVVKSEVDEEVFKLA
CCCHHHHHHHHCCCCEEEEEEEECCCCCCCEEEEEEECCCCCHHHEEEHHHHHHHHHHHH
KEIAQESSLYVTGTITEDNRSDLGYEMQVKSIEVISEAHDYPITPKNHGTEFLMDHRHLW
HHHHHCCCEEEEEEEECCCCCCCCEEEEHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
LRSKKQHAVMKIRNEVIRATYEFFNKDGFTKVDPPILTASAPEGTSELFHTKYFDQDAFL
HHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCHHHHHHHHHCCCHHHH
SQSGQLYLEAAAMAHGKVFSFGPTFRAEKSKTRRHLIEFWMIEGEMAFTNHAESLEIQEQ
CCCCCEEEEEEHHHCCCEEECCCCCCCHHHHHHHHHHHHHEECCCEEECCCCCHHHHHHH
YVTHVVKSVLENCKLELKILERDTSKLEKVATPFPRISYDDAIEFLKAEGFDDIEWGEDF
HHHHHHHHHHHCCCEEEEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCHHC
GAPHETAIANHYDLPVFITNYPTKIKPFYMQPNPENEETVLCADLIAPEGYGEIIGGSER
CCCCHHHHCCCCCCCEEEECCCCCCEEEEECCCCCCCCEEEEEHHHCCCCCCCCCCCCCC
VDDLELLEQRVKEHGLDEEAYSYYLDLRRYGSVPHCGFGLGLERTVAWISGVEHVRETAP
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
FPRLLNRLYP
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA