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The map label for this gene is msrB

Identifier: 15927004

GI number: 15927004

Start: 1430012

End: 1430440

Strand: Reverse

Name: msrB

Synonym: SA1256

Alternate gene names: 15927004

Gene position: 1430440-1430012 (Counterclockwise)

Preceding gene: 15927005

Following gene: 15927003

Centisome position: 50.82

GC content: 32.17

Gene sequence:

>429_bases
ATGCTTAAAAAAGATAAAAGTGAACTAACAGACATAGAATATATTGTTACACAAGAAAATGGCACTGAACCACCATTTAT
GAATGAATATTGGAATCATTTTGCTAAAGGGATTTATGTAGATAAGATTTCTGGTAAACCTTTATTTACATCTGAAGAAA
AGTTTCATTCTGAATGTGGATGGCCTAGCTTTTCTAAAGCGCTTGATGACGATGAAATTATAGAATTAGTCGACAAATCA
TTTGGTATGGTAAGAACTGAAGTGCGTTCAGAAGAATCAAATAGTCATTTAGGACACGTCTTTAATGATGGACCTAAAGA
AAGTGGCGGCTTAAGATACTGTATCAATTCCGCTGCAATTCAATTTATTCCATATGAAAAATTAGAAGAATTGGGTTATG
GCGATTTAATATCACATTTTGATAAGTAG

Upstream 100 bases:

>100_bases
TACCATCAAGATTATTATAAAAAGAACCCGGTACATTATTACCAATATCAACGTGGTTCAGGTAGAAAAGCGTTTATAGA
ATCACATTGGGGGAATCAAA

Downstream 100 bases:

>100_bases
GAGTGGAAAGTATGTTTAAAAAATTATTCGGAAAAGGCAAAGAAGTTCAGAAAGATATCGCAATTTATGCACCATTAACT
GGAGAATACGTGAAAATTGA

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MLKKDKSELTDIEYIVTQENGTEPPFMNEYWNHFAKGIYVDKISGKPLFTSEEKFHSECGWPSFSKALDDDEIIELVDKS
FGMVRTEVRSEESNSHLGHVFNDGPKESGGLRYCINSAAIQFIPYEKLEELGYGDLISHFDK

Sequences:

>Translated_142_residues
MLKKDKSELTDIEYIVTQENGTEPPFMNEYWNHFAKGIYVDKISGKPLFTSEEKFHSECGWPSFSKALDDDEIIELVDKS
FGMVRTEVRSEESNSHLGHVFNDGPKESGGLRYCINSAAIQFIPYEKLEELGYGDLISHFDK
>Mature_142_residues
MLKKDKSELTDIEYIVTQENGTEPPFMNEYWNHFAKGIYVDKISGKPLFTSEEKFHSECGWPSFSKALDDDEIIELVDKS
FGMVRTEVRSEESNSHLGHVFNDGPKESGGLRYCINSAAIQFIPYEKLEELGYGDLISHFDK

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family

Homologues:

Organism=Homo sapiens, GI301336164, Length=121, Percent_Identity=47.1074380165289, Blast_Score=116, Evalue=6e-27,
Organism=Homo sapiens, GI301336162, Length=121, Percent_Identity=47.1074380165289, Blast_Score=116, Evalue=6e-27,
Organism=Homo sapiens, GI73089054, Length=121, Percent_Identity=47.1074380165289, Blast_Score=116, Evalue=6e-27,
Organism=Homo sapiens, GI37620216, Length=121, Percent_Identity=47.1074380165289, Blast_Score=116, Evalue=7e-27,
Organism=Homo sapiens, GI117606353, Length=126, Percent_Identity=45.2380952380952, Blast_Score=104, Evalue=3e-23,
Organism=Escherichia coli, GI1788077, Length=126, Percent_Identity=42.8571428571429, Blast_Score=111, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17553450, Length=118, Percent_Identity=50.8474576271186, Blast_Score=123, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI115532676, Length=118, Percent_Identity=50.8474576271186, Blast_Score=122, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6319816, Length=119, Percent_Identity=31.9327731092437, Blast_Score=70, Evalue=1e-13,
Organism=Drosophila melanogaster, GI221378662, Length=126, Percent_Identity=45.2380952380952, Blast_Score=117, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24645799, Length=119, Percent_Identity=47.0588235294118, Blast_Score=116, Evalue=6e-27,
Organism=Drosophila melanogaster, GI45553335, Length=119, Percent_Identity=47.0588235294118, Blast_Score=115, Evalue=7e-27,
Organism=Drosophila melanogaster, GI21356369, Length=119, Percent_Identity=47.0588235294118, Blast_Score=115, Evalue=7e-27,
Organism=Drosophila melanogaster, GI221378664, Length=119, Percent_Identity=47.0588235294118, Blast_Score=115, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24645801, Length=130, Percent_Identity=43.0769230769231, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24645804, Length=130, Percent_Identity=43.0769230769231, Blast_Score=111, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MSRB_STAA1 (A7X2A9)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442001.1
- ProteinModelPortal:   A7X2A9
- SMR:   A7X2A9
- STRING:   A7X2A9
- EnsemblBacteria:   EBSTAT00000002994
- GeneID:   5560660
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1411
- eggNOG:   COG0229
- GeneTree:   EBGT00050000024012
- HOGENOM:   HBG715255
- OMA:   RIGDLAF
- ProtClustDB:   PRK00222
- BioCyc:   SAUR418127:SAHV_1411-MONOMER
- HAMAP:   MF_01400
- InterPro:   IPR002579
- InterPro:   IPR011057
- Gene3D:   G3DSA:2.170.150.20
- TIGRFAMs:   TIGR00357

Pfam domain/function: PF01641 SelR; SSF51316 Mss4_like

EC number: =1.8.4.12

Molecular weight: Translated: 16263; Mature: 16263

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: NA

Important sites: ACT_SITE 114-114

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKKDKSELTDIEYIVTQENGTEPPFMNEYWNHFAKGIYVDKISGKPLFTSEEKFHSECG
CCCCCCHHCCCEEEEEECCCCCCCCHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHCC
WPSFSKALDDDEIIELVDKSFGMVRTEVRSEESNSHLGHVFNDGPKESGGLRYCINSAAI
CCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCHHH
QFIPYEKLEELGYGDLISHFDK
EECCHHHHHHCCCHHHHHHCCC
>Mature Secondary Structure
MLKKDKSELTDIEYIVTQENGTEPPFMNEYWNHFAKGIYVDKISGKPLFTSEEKFHSECG
CCCCCCHHCCCEEEEEECCCCCCCCHHHHHHHHHHCCEEEECCCCCCCCCCHHHHHHHCC
WPSFSKALDDDEIIELVDKSFGMVRTEVRSEESNSHLGHVFNDGPKESGGLRYCINSAAI
CCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCHHH
QFIPYEKLEELGYGDLISHFDK
EECCHHHHHHCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA