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The map label for this gene is murG

Identifier: 15926999

GI number: 15926999

Start: 1425606

End: 1426676

Strand: Reverse

Name: murG

Synonym: SA1251

Alternate gene names: 15926999

Gene position: 1426676-1425606 (Counterclockwise)

Preceding gene: 15927000

Following gene: 15926998

Centisome position: 50.68

GC content: 29.79

Gene sequence:

>1071_bases
ATGACGAAAATCGCATTTACCGGAGGGGGAACAGTTGGACACGTATCAGTAAATTTAAGTTTAATTCCAACTGCATTATC
ACAAGGTTATGAAGCGCTTTATATTGGTTCTAAAAATGGTATTGAAAGAGAAATGATTGAATCACAACTACCAGAAATTA
AGTATTATCCTATTTCGAGTGGTAAATTAAGAAGATATATTTCTTTAGAAAATGCCAAAGACGTATTTAAAGTATTGAAA
GGTATTCTTGATGCTCGTAAAGTTTTGAAAAAAGAAAAACCTGATCTATTATTTTCAAAAGGTGGATTTGTATCTGTGCC
TGTTGTTATTGCAGCCAAATCATTAAATATACCAACTATTATTCATGAATCTGACTTAACACCAGGATTAGCGAATAAGA
TAGCACTTAAATTTGCCAAGAAAATATATACAACATTTGAAGAAACGCTAAACTACTTACCTAAAGAGAAAGCTGATTTT
ATTGGAGCAACAATTCGAGAAGATTTAAAAAATGGTAATGCACATAATGGTTATCAATTAACAGGCTTTAATGAAAATAA
AAAAGTTTTACTTGTTATGGGTGGAAGCTTAGGAAGTAAAAAATTAAATAGCATTATTCGCGAAAACTTAGATGCATTAT
TACAACAATATCAAGTGATACATTTAACTGGTAAAGGATTAAAAGATGCTCAAGTTAAAAAATCAGGATATATACAATAT
GAATTTGTTAAAGAGGATTTAACAGATTTATTAGCAATTACGGATACAGTAATAAGTAGAGCTGGATCAAATGCGATTTA
TGAGTTCTTAACATTACGTATACCAATGTTATTAGTACCATTAGGTTTAGATCAATCCCGAGGCGACCAAATTGACAATG
CAAATCATTTTGCTGATAAAGGTTATGCTAAAACGATTGATGAAGAACAATTAACAGCACAAATTTTATTACAAGAACTA
AATGAAATGGAACAGGAAAGAACTCGAATTATCAATAATATGAAATCGTATGAACAAAGTTATACGAAAGAAGCTTTATT
TGATAAGATGATTAAAGACGCATTGAATTAA

Upstream 100 bases:

>100_bases
TTCATAAGGTCGGTGAACAATTAATGGAATATCCGCCATATGATAAAGGTGAACCATTTTATGCATATTATAAAAATTTA
AAAGAATAGAGGTAATATTA

Downstream 100 bases:

>100_bases
TGGGGGGTAATGCTTTATGAGTCAATGGAAACGTATCTCTTTGCTCATCGTTTTTGCATTGGTTTTTGGAATTATCGCGT
TTTTCCACGAATCAAGACTA

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MTKIAFTGGGTVGHVSVNLSLIPTALSQGYEALYIGSKNGIEREMIESQLPEIKYYPISSGKLRRYISLENAKDVFKVLK
GILDARKVLKKEKPDLLFSKGGFVSVPVVIAAKSLNIPTIIHESDLTPGLANKIALKFAKKIYTTFEETLNYLPKEKADF
IGATIREDLKNGNAHNGYQLTGFNENKKVLLVMGGSLGSKKLNSIIRENLDALLQQYQVIHLTGKGLKDAQVKKSGYIQY
EFVKEDLTDLLAITDTVISRAGSNAIYEFLTLRIPMLLVPLGLDQSRGDQIDNANHFADKGYAKTIDEEQLTAQILLQEL
NEMEQERTRIINNMKSYEQSYTKEALFDKMIKDALN

Sequences:

>Translated_356_residues
MTKIAFTGGGTVGHVSVNLSLIPTALSQGYEALYIGSKNGIEREMIESQLPEIKYYPISSGKLRRYISLENAKDVFKVLK
GILDARKVLKKEKPDLLFSKGGFVSVPVVIAAKSLNIPTIIHESDLTPGLANKIALKFAKKIYTTFEETLNYLPKEKADF
IGATIREDLKNGNAHNGYQLTGFNENKKVLLVMGGSLGSKKLNSIIRENLDALLQQYQVIHLTGKGLKDAQVKKSGYIQY
EFVKEDLTDLLAITDTVISRAGSNAIYEFLTLRIPMLLVPLGLDQSRGDQIDNANHFADKGYAKTIDEEQLTAQILLQEL
NEMEQERTRIINNMKSYEQSYTKEALFDKMIKDALN
>Mature_355_residues
TKIAFTGGGTVGHVSVNLSLIPTALSQGYEALYIGSKNGIEREMIESQLPEIKYYPISSGKLRRYISLENAKDVFKVLKG
ILDARKVLKKEKPDLLFSKGGFVSVPVVIAAKSLNIPTIIHESDLTPGLANKIALKFAKKIYTTFEETLNYLPKEKADFI
GATIREDLKNGNAHNGYQLTGFNENKKVLLVMGGSLGSKKLNSIIRENLDALLQQYQVIHLTGKGLKDAQVKKSGYIQYE
FVKEDLTDLLAITDTVISRAGSNAIYEFLTLRIPMLLVPLGLDQSRGDQIDNANHFADKGYAKTIDEEQLTAQILLQELN
EMEQERTRIINNMKSYEQSYTKEALFDKMIKDALN

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=330, Percent_Identity=27.2727272727273, Blast_Score=118, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_STAA1 (A7X2A2)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001441996.1
- ProteinModelPortal:   A7X2A2
- SMR:   A7X2A2
- STRING:   A7X2A2
- EnsemblBacteria:   EBSTAT00000003300
- GeneID:   5560816
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1406
- eggNOG:   COG0707
- GeneTree:   EBGT00050000024209
- HOGENOM:   HBG617076
- OMA:   HICGKGN
- ProtClustDB:   PRK00726
- BioCyc:   SAUR418127:SAHV_1406-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 39727; Mature: 39596

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKIAFTGGGTVGHVSVNLSLIPTALSQGYEALYIGSKNGIEREMIESQLPEIKYYPISS
CCEEEEECCCEEEEEEEEEEEEHHHHHCCCEEEEECCCCCCHHHHHHHHCCCEEEEECCC
GKLRRYISLENAKDVFKVLKGILDARKVLKKEKPDLLFSKGGFVSVPVVIAAKSLNIPTI
CCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEECCEEEEECCCCCEE
IHESDLTPGLANKIALKFAKKIYTTFEETLNYLPKEKADFIGATIREDLKNGNAHNGYQL
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEE
TGFNENKKVLLVMGGSLGSKKLNSIIRENLDALLQQYQVIHLTGKGLKDAQVKKSGYIQY
EEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCHHHHHCCCEEE
EFVKEDLTDLLAITDTVISRAGSNAIYEFLTLRIPMLLVPLGLDQSRGDQIDNANHFADK
EEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHCC
GYAKTIDEEQLTAQILLQELNEMEQERTRIINNMKSYEQSYTKEALFDKMIKDALN
CHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TKIAFTGGGTVGHVSVNLSLIPTALSQGYEALYIGSKNGIEREMIESQLPEIKYYPISS
CEEEEECCCEEEEEEEEEEEEHHHHHCCCEEEEECCCCCCHHHHHHHHCCCEEEEECCC
GKLRRYISLENAKDVFKVLKGILDARKVLKKEKPDLLFSKGGFVSVPVVIAAKSLNIPTI
CCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEECCEEEEECCCCCEE
IHESDLTPGLANKIALKFAKKIYTTFEETLNYLPKEKADFIGATIREDLKNGNAHNGYQL
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEE
TGFNENKKVLLVMGGSLGSKKLNSIIRENLDALLQQYQVIHLTGKGLKDAQVKKSGYIQY
EEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCHHHHHCCCEEE
EFVKEDLTDLLAITDTVISRAGSNAIYEFLTLRIPMLLVPLGLDQSRGDQIDNANHFADK
EEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHCC
GYAKTIDEEQLTAQILLQELNEMEQERTRIINNMKSYEQSYTKEALFDKMIKDALN
CHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA