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The map label for this gene is dapB

Identifier: 15926976

GI number: 15926976

Start: 1402887

End: 1403609

Strand: Direct

Name: dapB

Synonym: SA1228

Alternate gene names: 15926976

Gene position: 1402887-1403609 (Clockwise)

Preceding gene: 15926975

Following gene: 15926977

Centisome position: 49.84

GC content: 36.1

Gene sequence:

>723_bases
GTGAAAATATTACTAATTGGCTATGGTGCAATGAATCAACGCGTTGCTAGATTAGCAGAAGAAAAAGGACATGAAATCGT
TGGGGTCATTGAAAATACACCGAAAGCAACAACGCCATATCAACAATATCAACATATTGCAGATGTTAAAGATGCCGATG
TTGCAATAGATTTTTCAAATCCGAATCTATTATTCCCATTATTAGATGAAGAGTTTCATTTGCCATTAGTTGTGGCAACA
ACTGGCGAGAAAGAAAAACTACTTAATAAGTTAGATGAATTGAGTCAAAATATGCCTGTATTTTTCAGCGCGAACATGAG
TTATGGCGTTCATGCACTGACTAAAATTTTAGCAGCTGCTGTTCCCCTACTTGATGATTTCGACATCGAATTGACTGAGG
CACATCATAATAAAAAAGTAGATGCACCAAGTGGTACGTTAGAAAAATTGTATGATGTGATCGTATCTTTGAAAGAAAAT
GTAACACCTGTGTATGATAGACATGAATTAAATGAAAAACGCCAGCCACAAGATATTGGTATACATTCTATTCGTGGAGG
TACGATTGTCGGTGAACATGAAGTTCTATTTGCTGGCACTGATGAAACGATTCAAATCACACATCGTGCACAATCAAAAG
ATATTTTTGCGAATGGTGCTATACAAGCAGCAGAACGCTTAGTTAATAAACCAAACGGCTTTTATACGTTTGACAACTTA
TAA

Upstream 100 bases:

>100_bases
TTGGAAACTATGAATTACGTTTACCATTGGTTAGCCTAGAAGATACAGATACTAAAGTGCTTCGTGAAGCATATGACACA
TTTAAAGCGGGTGAAAATGA

Downstream 100 bases:

>100_bases
ACATATTAAAGGAGATCGATTATTTTATGGTACAACATTTAACAGCTGAAGAAATTATTCAATATATAAGTGATGCTAAA
AAGTCTACACCAATAAAAGT

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MKILLIGYGAMNQRVARLAEEKGHEIVGVIENTPKATTPYQQYQHIADVKDADVAIDFSNPNLLFPLLDEEFHLPLVVAT
TGEKEKLLNKLDELSQNMPVFFSANMSYGVHALTKILAAAVPLLDDFDIELTEAHHNKKVDAPSGTLEKLYDVIVSLKEN
VTPVYDRHELNEKRQPQDIGIHSIRGGTIVGEHEVLFAGTDETIQITHRAQSKDIFANGAIQAAERLVNKPNGFYTFDNL

Sequences:

>Translated_240_residues
MKILLIGYGAMNQRVARLAEEKGHEIVGVIENTPKATTPYQQYQHIADVKDADVAIDFSNPNLLFPLLDEEFHLPLVVAT
TGEKEKLLNKLDELSQNMPVFFSANMSYGVHALTKILAAAVPLLDDFDIELTEAHHNKKVDAPSGTLEKLYDVIVSLKEN
VTPVYDRHELNEKRQPQDIGIHSIRGGTIVGEHEVLFAGTDETIQITHRAQSKDIFANGAIQAAERLVNKPNGFYTFDNL
>Mature_240_residues
MKILLIGYGAMNQRVARLAEEKGHEIVGVIENTPKATTPYQQYQHIADVKDADVAIDFSNPNLLFPLLDEEFHLPLVVAT
TGEKEKLLNKLDELSQNMPVFFSANMSYGVHALTKILAAAVPLLDDFDIELTEAHHNKKVDAPSGTLEKLYDVIVSLKEN
VTPVYDRHELNEKRQPQDIGIHSIRGGTIVGEHEVLFAGTDETIQITHRAQSKDIFANGAIQAAERLVNKPNGFYTFDNL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=191, Percent_Identity=37.17277486911, Blast_Score=116, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_STAA1 (A7X273)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001441974.1
- ProteinModelPortal:   A7X273
- SMR:   A7X273
- STRING:   A7X273
- EnsemblBacteria:   EBSTAT00000003983
- GeneID:   5559581
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1384
- eggNOG:   COG0289
- GeneTree:   EBGT00050000024897
- HOGENOM:   HBG594002
- OMA:   GALKACE
- ProtClustDB:   PRK00048
- BioCyc:   SAUR418127:SAHV_1384-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 26727; Mature: 26727

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILLIGYGAMNQRVARLAEEKGHEIVGVIENTPKATTPYQQYQHIADVKDADVAIDFSN
CEEEEEECCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHCCCCCCEEEEECC
PNLLFPLLDEEFHLPLVVATTGEKEKLLNKLDELSQNMPVFFSANMSYGVHALTKILAAA
CCEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHH
VPLLDDFDIELTEAHHNKKVDAPSGTLEKLYDVIVSLKENVTPVYDRHELNEKRQPQDIG
HCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCC
IHSIRGGTIVGEHEVLFAGTDETIQITHRAQSKDIFANGAIQAAERLVNKPNGFYTFDNL
EEEECCCEEECCCEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEECCC
>Mature Secondary Structure
MKILLIGYGAMNQRVARLAEEKGHEIVGVIENTPKATTPYQQYQHIADVKDADVAIDFSN
CEEEEEECCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHCCCCCCEEEEECC
PNLLFPLLDEEFHLPLVVATTGEKEKLLNKLDELSQNMPVFFSANMSYGVHALTKILAAA
CCEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHH
VPLLDDFDIELTEAHHNKKVDAPSGTLEKLYDVIVSLKENVTPVYDRHELNEKRQPQDIG
HCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCC
IHSIRGGTIVGEHEVLFAGTDETIQITHRAQSKDIFANGAIQAAERLVNKPNGFYTFDNL
EEEECCCEEECCCEEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA