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The map label for this gene is rsmB [H]

Identifier: 15926800

GI number: 15926800

Start: 1199155

End: 1200540

Strand: Direct

Name: rsmB [H]

Synonym: SA1060

Alternate gene names: 15926800

Gene position: 1199155-1200540 (Clockwise)

Preceding gene: 15926799

Following gene: 15926801

Centisome position: 42.6

GC content: 33.33

Gene sequence:

>1386_bases
ATTAGCTGGGAAAAAGAGAATGTTAGCTGCCAATTATTTAAGTGGTGCGCAAAACACACTAGTAGGGAAGAAACTTATAT
GATCGAAAACGTGAGAAGTCTTGCTTTTGACACGATTCAAGATATATTAAATGAAGGTGCGTATAGTAACTTGCGTATCA
ATGAAGTGTTGTCAGAAAATGAATTAAATGCAATGGATAAGGCTTTATTTACAGAAATTGTCTACGGAACCGTTAAAAGA
AAATATACGTTAGATTTTTATTTAAAGCCTTTTGTGAAAACAAAGATTAAGGCATGGGTTAGGCAATTATTATGGATGAG
TATTTATCAATATGTATATTTAGATAAAGTTCCAAATCATGCCATTATTAATGAAGCAGTTGAAATAGCAAAAGAACGCG
GTGGCTATCATAATGGTAATGTCGTAAATGGTATTTTACGTACAATGATGCGTAGTGACTTACCTGATTTTAATGAAATT
GCAGATCCTAAAAAAAGAATGGCAATCGAGTATAGTATGCCGAAGTGGATTATAGATCATTGGGCAACACATTATGGTCT
CGAAGAAACTGAAACAATTTTACAGTCATTTTTAGAAACGACATCAACAACTGTGCGTGCCAACCTGACGCGAGCATCAT
TAGATGATATTATTGAAAAGTTGCAAGACGAAGGTTATGACGTTGAAAAAGATCATGACTTACCTTATTGTCTCCATATA
GGAGGACAACCAATTATTCATTCTCGTTCATTTAAAGATGGATTCGTTTCAATTCAAGATAAAAGCTCAATGTTTGTTGC
ACACATTATGAATGTAGACCGACATGATCACGTATTAGATGCATGTAGTGCACCTGGCGGTAAAGCTTGTCACATTGCTG
AAGTTTTAATGCCAGAAGGGCAAGTTGACGCTTCAGATATACATGATCACAAAATAGACTTAATTAATTTTAATATAAAA
AAATTACGATTAACAAATATTAAGGCTTTTCAACATGATGCGACAAAACCTTATGATAAAACATACGATAAGATACTTGT
TGATGCACCATGTAGCGGATTAGGTGTAATGAGACATAAGCCGGAGATTAAGTATACTCAAAGCAAACAACATATTGAGT
CACTAGTTGAATTACAGCTTGAAATATTGGAAAATGTAAAAAACAATGTAAAAATAGGTGGCGAAATCATCTATTCAACA
TGTACAATTGAGCAACTAGAAAATGAAAACGTGATTTATACGTTTCTGAAAAATAATAAAAACTTCGAATTTGAACCGTT
TCAACATCCGATAACTGGAGAGTTGGTCAAAACGTTACAAATCATGCCGCAAGACTTTAATTCAGATGGATTCTTTATCA
CTAAGATAAAAAGAAAGGACAATTAG

Upstream 100 bases:

>100_bases
CTAATAAGATAAACGAGCCTGGAACCATTATAGAAACGACTAAAAAAGCCATTATTGTTGCTACAAATGATAATGAAGCT
GTTGCAATTAAAGATATGCA

Downstream 100 bases:

>100_bases
GAATGATAACTGCTGAAAAGAAAAAGAAGAATAAATTTCTTCCAAATTTTGACAAGCAATCAATATATTCATTGCGATTT
GACGAAATGCAAAACTGGCT

Product: hypothetical protein

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MSWEKENVSCQLFKWCAKHTSREETYMIENVRSLAFDTIQDILNEGAYSNLRINEVLSENELNAMDKALFTEIVYGTVKR
KYTLDFYLKPFVKTKIKAWVRQLLWMSIYQYVYLDKVPNHAIINEAVEIAKERGGYHNGNVVNGILRTMMRSDLPDFNEI
ADPKKRMAIEYSMPKWIIDHWATHYGLEETETILQSFLETTSTTVRANLTRASLDDIIEKLQDEGYDVEKDHDLPYCLHI
GGQPIIHSRSFKDGFVSIQDKSSMFVAHIMNVDRHDHVLDACSAPGGKACHIAEVLMPEGQVDASDIHDHKIDLINFNIK
KLRLTNIKAFQHDATKPYDKTYDKILVDAPCSGLGVMRHKPEIKYTQSKQHIESLVELQLEILENVKNNVKIGGEIIYST
CTIEQLENENVIYTFLKNNKNFEFEPFQHPITGELVKTLQIMPQDFNSDGFFITKIKRKDN

Sequences:

>Translated_461_residues
MSWEKENVSCQLFKWCAKHTSREETYMIENVRSLAFDTIQDILNEGAYSNLRINEVLSENELNAMDKALFTEIVYGTVKR
KYTLDFYLKPFVKTKIKAWVRQLLWMSIYQYVYLDKVPNHAIINEAVEIAKERGGYHNGNVVNGILRTMMRSDLPDFNEI
ADPKKRMAIEYSMPKWIIDHWATHYGLEETETILQSFLETTSTTVRANLTRASLDDIIEKLQDEGYDVEKDHDLPYCLHI
GGQPIIHSRSFKDGFVSIQDKSSMFVAHIMNVDRHDHVLDACSAPGGKACHIAEVLMPEGQVDASDIHDHKIDLINFNIK
KLRLTNIKAFQHDATKPYDKTYDKILVDAPCSGLGVMRHKPEIKYTQSKQHIESLVELQLEILENVKNNVKIGGEIIYST
CTIEQLENENVIYTFLKNNKNFEFEPFQHPITGELVKTLQIMPQDFNSDGFFITKIKRKDN
>Mature_460_residues
SWEKENVSCQLFKWCAKHTSREETYMIENVRSLAFDTIQDILNEGAYSNLRINEVLSENELNAMDKALFTEIVYGTVKRK
YTLDFYLKPFVKTKIKAWVRQLLWMSIYQYVYLDKVPNHAIINEAVEIAKERGGYHNGNVVNGILRTMMRSDLPDFNEIA
DPKKRMAIEYSMPKWIIDHWATHYGLEETETILQSFLETTSTTVRANLTRASLDDIIEKLQDEGYDVEKDHDLPYCLHIG
GQPIIHSRSFKDGFVSIQDKSSMFVAHIMNVDRHDHVLDACSAPGGKACHIAEVLMPEGQVDASDIHDHKIDLINFNIKK
LRLTNIKAFQHDATKPYDKTYDKILVDAPCSGLGVMRHKPEIKYTQSKQHIESLVELQLEILENVKNNVKIGGEIIYSTC
TIEQLENENVIYTFLKNNKNFEFEPFQHPITGELVKTLQIMPQDFNSDGFFITKIKRKDN

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=323, Percent_Identity=28.1733746130031, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI76150623, Length=323, Percent_Identity=28.1733746130031, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI32698918, Length=210, Percent_Identity=32.3809523809524, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI301336155, Length=188, Percent_Identity=31.3829787234043, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI39995082, Length=188, Percent_Identity=31.3829787234043, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI270288818, Length=324, Percent_Identity=24.0740740740741, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI8922322, Length=315, Percent_Identity=23.8095238095238, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI23199998, Length=314, Percent_Identity=23.8853503184713, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI270288816, Length=314, Percent_Identity=23.8853503184713, Blast_Score=86, Evalue=7e-17,
Organism=Escherichia coli, GI2367212, Length=444, Percent_Identity=28.6036036036036, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI87081985, Length=248, Percent_Identity=27.0161290322581, Blast_Score=105, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17536757, Length=298, Percent_Identity=28.5234899328859, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI25143471, Length=205, Percent_Identity=27.8048780487805, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71998419, Length=225, Percent_Identity=28.4444444444444, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI115534021, Length=166, Percent_Identity=31.3253012048193, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17509941, Length=282, Percent_Identity=29.4326241134752, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324268, Length=284, Percent_Identity=27.112676056338, Blast_Score=96, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6319447, Length=182, Percent_Identity=31.3186813186813, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI22024126, Length=233, Percent_Identity=31.7596566523605, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21355201, Length=185, Percent_Identity=30.2702702702703, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24668781, Length=250, Percent_Identity=25.6, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356513, Length=250, Percent_Identity=25.6, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356579, Length=184, Percent_Identity=25.5434782608696, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 53291; Mature: 53160

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWEKENVSCQLFKWCAKHTSREETYMIENVRSLAFDTIQDILNEGAYSNLRINEVLSEN
CCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHCCC
ELNAMDKALFTEIVYGTVKRKYTLDFYLKPFVKTKIKAWVRQLLWMSIYQYVYLDKVPNH
HHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
AIINEAVEIAKERGGYHNGNVVNGILRTMMRSDLPDFNEIADPKKRMAIEYSMPKWIIDH
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHCCHHHHEEEEECCCHHHHHH
WATHYGLEETETILQSFLETTSTTVRANLTRASLDDIIEKLQDEGYDVEKDHDLPYCLHI
HHHHCCCHHHHHHHHHHHHHHCHHHEECCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEE
GGQPIIHSRSFKDGFVSIQDKSSMFVAHIMNVDRHDHVLDACSAPGGKACHIAEVLMPEG
CCCCEEECCCCCCCEEEEECCCHHHHHHHHCCCCHHHHHHHHCCCCCCCEEHHHHHCCCC
QVDASDIHDHKIDLINFNIKKLRLTNIKAFQHDATKPYDKTYDKILVDAPCSGLGVMRHK
CCCCCCCCCCEEEEEECCEEEEEEECCHHHHCCCCCCCHHHHHHEEEECCCCCCCCCCCC
PEIKYTQSKQHIESLVELQLEILENVKNNVKIGGEIIYSTCTIEQLENENVIYTFLKNNK
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEECCEEEEEEEEHHHHCCCCEEEEEEECCC
NFEFEPFQHPITGELVKTLQIMPQDFNSDGFFITKIKRKDN
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCC
>Mature Secondary Structure 
SWEKENVSCQLFKWCAKHTSREETYMIENVRSLAFDTIQDILNEGAYSNLRINEVLSEN
CCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHCCC
ELNAMDKALFTEIVYGTVKRKYTLDFYLKPFVKTKIKAWVRQLLWMSIYQYVYLDKVPNH
HHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
AIINEAVEIAKERGGYHNGNVVNGILRTMMRSDLPDFNEIADPKKRMAIEYSMPKWIIDH
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHCCHHHHEEEEECCCHHHHHH
WATHYGLEETETILQSFLETTSTTVRANLTRASLDDIIEKLQDEGYDVEKDHDLPYCLHI
HHHHCCCHHHHHHHHHHHHHHCHHHEECCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEE
GGQPIIHSRSFKDGFVSIQDKSSMFVAHIMNVDRHDHVLDACSAPGGKACHIAEVLMPEG
CCCCEEECCCCCCCEEEEECCCHHHHHHHHCCCCHHHHHHHHCCCCCCCEEHHHHHCCCC
QVDASDIHDHKIDLINFNIKKLRLTNIKAFQHDATKPYDKTYDKILVDAPCSGLGVMRHK
CCCCCCCCCCEEEEEECCEEEEEEECCHHHHCCCCCCCHHHHHHEEEECCCCCCCCCCCC
PEIKYTQSKQHIESLVELQLEILENVKNNVKIGGEIIYSTCTIEQLENENVIYTFLKNNK
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEECCEEEEEEEEHHHHCCCCEEEEEEECCC
NFEFEPFQHPITGELVKTLQIMPQDFNSDGFFITKIKRKDN
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377; 9086272 [H]