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The map label for this gene is scn [H]

Identifier: 15926742

GI number: 15926742

Start: 1136409

End: 1136759

Strand: Direct

Name: scn [H]

Synonym: SA1004

Alternate gene names: 15926742

Gene position: 1136409-1136759 (Clockwise)

Preceding gene: 15926741

Following gene: 15926745

Centisome position: 40.37

GC content: 28.77

Gene sequence:

>351_bases
ATGAAATTTAAAAAATATATATTAACAGGAACATTAGCATTACTTTTATCATCAACTGGGATAGCAACTATAGAAGGGAA
TAAAGCAGATGCAAGTAGTCTGGACAAATATTTAACTGAAAGTCAGTTTCATGATAAACGCATAGCAGAAGAATTAAGAA
CTTTACTTAACAAATCGAATGTATATGCATTAGCTGCAGGAAGCTTAAATCCATATTATAAACGTACGATTATGATGAAT
GAATATAGAGCTAAAGCGGCACTTAAGAAAAATGATTTCGTATCAATGGCTGATGCTAAAGTTGCATTAGAAAAAATATA
CAAAGAAATTGATGAAATTATAAATAGATAA

Upstream 100 bases:

>100_bases
TTTATTAATAAAACGACTATGCTATTTAATGCCAGGTTAATGTAACTTTCCTAAAATTGACTATATAATCGTTAAGTATC
AATTTTAAGGAGAGTTTACA

Downstream 100 bases:

>100_bases
TAAATAAAACAGGTTGAGACAAAAAATGGTCTTAACCTGTTTTCAATTTGCATATGTGATAAATTCTATATCAAAATGCT
TATGTATAATGAATGACATT

Product: hypothetical protein

Products: NA

Alternate protein names: SCIN [H]

Number of amino acids: Translated: 116; Mature: 116

Protein sequence:

>116_residues
MKFKKYILTGTLALLLSSTGIATIEGNKADASSLDKYLTESQFHDKRIAEELRTLLNKSNVYALAAGSLNPYYKRTIMMN
EYRAKAALKKNDFVSMADAKVALEKIYKEIDEIINR

Sequences:

>Translated_116_residues
MKFKKYILTGTLALLLSSTGIATIEGNKADASSLDKYLTESQFHDKRIAEELRTLLNKSNVYALAAGSLNPYYKRTIMMN
EYRAKAALKKNDFVSMADAKVALEKIYKEIDEIINR
>Mature_116_residues
MKFKKYILTGTLALLLSSTGIATIEGNKADASSLDKYLTESQFHDKRIAEELRTLLNKSNVYALAAGSLNPYYKRTIMMN
EYRAKAALKKNDFVSMADAKVALEKIYKEIDEIINR

Specific function: Involved in countering the first line of host defense mechanisms. Efficiently inhibits opsonization, phagocytosis and killing of S.aureus by human neutrophils. Acts by binding and stabilizing human C3 convertases (C4b2a and C3bBb), leading to their inacti

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SCIN family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021612 [H]

Pfam domain/function: PF11546 CompInhib_SCIN [H]

EC number: NA

Molecular weight: Translated: 13114; Mature: 13114

Theoretical pI: Translated: 9.87; Mature: 9.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFKKYILTGTLALLLSSTGIATIEGNKADASSLDKYLTESQFHDKRIAEELRTLLNKSN
CCHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VYALAAGSLNPYYKRTIMMNEYRAKAALKKNDFVSMADAKVALEKIYKEIDEIINR
EEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKFKKYILTGTLALLLSSTGIATIEGNKADASSLDKYLTESQFHDKRIAEELRTLLNKSN
CCHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VYALAAGSLNPYYKRTIMMNEYRAKAALKKNDFVSMADAKVALEKIYKEIDEIINR
EEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA