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The map label for this gene is isdC

Identifier: 15926715

GI number: 15926715

Start: 1108059

End: 1108742

Strand: Direct

Name: isdC

Synonym: SA0978

Alternate gene names: 15926715

Gene position: 1108059-1108742 (Clockwise)

Preceding gene: 15926712

Following gene: 15926716

Centisome position: 39.37

GC content: 32.02

Gene sequence:

>684_bases
TTGAAAAATATTTTAAAAGTTTTTAATACAACGATTTTAGCGTTAATTATCATCATCGCGACATTCAGTAATTCTGCAAA
TGCCGCAGATAGCGGTACTTTGAATTATGAGGTTTACAAATACAATACCAATGACACGTCAATTGCTAATGACTATTTTA
ATAAACCGGCAAAGTACATTAAGAAAAATGGTAAATTGTATGTTCAAATAACTGTCAACCACAGTCATTGGATTACTGGA
ATGAGTATCGAAGGACATAAAGAAAATATTATTAGTAAAAACACTGCCAAAGATGAACGCACTTCTGAATTTGAAGTAAG
TAAGTTGAACGGTAAAATAGATGGAAAAATTGACGTTTATATCGATGAAAAAGTAAATGGAAAGCCATTCAAATATGACC
ATCATTACAACATTACATATAAATTTAATGGACCAACTGATGTAGCAGGTGCTAATGCACCAGGTAAAGATGATAAAAAT
TCTGCTTCAGGTAGTGACAAAGGATCTGATGGAACGACTACTGGTCAAAGTGAATCTAATAGTTCGAATAAAGACAAAGT
AGAAAATCCACAAACAAATGCTGGTACACCTGCATATATATATGCAATACCAGTTGCATCCTTAGCATTATTAATCGCAA
TCACATTGTTTGTTAGAAAAAAATCTAAAGGCAATGTGGAATAA

Upstream 100 bases:

>100_bases
ATAATAAATTGATTATAAAATAAATATTGACAATGATAATCATTATTATTTATGATTTTACTAAAGACTTAAAAGCAATC
ATAAAAAGGAGGATTATGTT

Downstream 100 bases:

>100_bases
TGAGAAATGTTAAACAAATTGCTACAAAATCTATTATAGCTATTATTAGCTTATGTATACTTACATATACAACAATGATT
GGTAGCGTGTTGGCTGATGA

Product: hypothetical protein

Products: NA

Alternate protein names: Staphylococcal iron-regulated protein D

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MKNILKVFNTTILALIIIIATFSNSANAADSGTLNYEVYKYNTNDTSIANDYFNKPAKYIKKNGKLYVQITVNHSHWITG
MSIEGHKENIISKNTAKDERTSEFEVSKLNGKIDGKIDVYIDEKVNGKPFKYDHHYNITYKFNGPTDVAGANAPGKDDKN
SASGSDKGSDGTTTGQSESNSSNKDKVENPQTNAGTPAYIYAIPVASLALLIAITLFVRKKSKGNVE

Sequences:

>Translated_227_residues
MKNILKVFNTTILALIIIIATFSNSANAADSGTLNYEVYKYNTNDTSIANDYFNKPAKYIKKNGKLYVQITVNHSHWITG
MSIEGHKENIISKNTAKDERTSEFEVSKLNGKIDGKIDVYIDEKVNGKPFKYDHHYNITYKFNGPTDVAGANAPGKDDKN
SASGSDKGSDGTTTGQSESNSSNKDKVENPQTNAGTPAYIYAIPVASLALLIAITLFVRKKSKGNVE
>Mature_227_residues
MKNILKVFNTTILALIIIIATFSNSANAADSGTLNYEVYKYNTNDTSIANDYFNKPAKYIKKNGKLYVQITVNHSHWITG
MSIEGHKENIISKNTAKDERTSEFEVSKLNGKIDGKIDVYIDEKVNGKPFKYDHHYNITYKFNGPTDVAGANAPGKDDKN
SASGSDKGSDGTTTGQSESNSSNKDKVENPQTNAGTPAYIYAIPVASLALLIAITLFVRKKSKGNVE

Specific function: Involved in heme (porphyrin) scavenging. Binds hemoglobin and almost exclusively free-base protoporphyrin IX. Probably has a role as the central conduit of the isd heme uptake system, i.e., mediates the transfer of the iron-containing nutrient from isdABH

COG id: COG5386

COG function: function code M; Cell surface protein

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 NEAT domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ISDC_STAA1 (A7X149)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001441712.1
- ProteinModelPortal:   A7X149
- SMR:   A7X149
- STRING:   A7X149
- EnsemblBacteria:   EBSTAT00000003429
- GeneID:   5560719
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1122
- eggNOG:   COG5386
- GeneTree:   EBGT00050000023721
- HOGENOM:   HBG692914
- OMA:   VEFKIDD
- ProtClustDB:   CLSK885154
- BioCyc:   SAUR418127:SAHV_1122-MONOMER
- InterPro:   IPR019909
- InterPro:   IPR006635
- InterPro:   IPR017505
- SMART:   SM00725
- TIGRFAMs:   TIGR03656
- TIGRFAMs:   TIGR03068

Pfam domain/function: PF05031 NEAT

EC number: NA

Molecular weight: Translated: 24855; Mature: 24855

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: PS50978 NEAT

Important sites: BINDING 47-47 BINDING 48-48 BINDING 136-136

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNILKVFNTTILALIIIIATFSNSANAADSGTLNYEVYKYNTNDTSIANDYFNKPAKYI
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHCCHHHHH
KKNGKLYVQITVNHSHWITGMSIEGHKENIISKNTAKDERTSEFEVSKLNGKIDGKIDVY
HCCCCEEEEEEECCCEEEEEEEECCCHHHHCCCCCCCCCCCCCEEEEECCCEECCEEEEE
IDEKVNGKPFKYDHHYNITYKFNGPTDVAGANAPGKDDKNSASGSDKGSDGTTTGQSESN
ECCCCCCCCEEECCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SSNKDKVENPQTNAGTPAYIYAIPVASLALLIAITLFVRKKSKGNVE
CCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKNILKVFNTTILALIIIIATFSNSANAADSGTLNYEVYKYNTNDTSIANDYFNKPAKYI
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHCCHHHHH
KKNGKLYVQITVNHSHWITGMSIEGHKENIISKNTAKDERTSEFEVSKLNGKIDGKIDVY
HCCCCEEEEEEECCCEEEEEEEECCCHHHHCCCCCCCCCCCCCEEEEECCCEECCEEEEE
IDEKVNGKPFKYDHHYNITYKFNGPTDVAGANAPGKDDKNSASGSDKGSDGTTTGQSESN
ECCCCCCCCEEECCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
SSNKDKVENPQTNAGTPAYIYAIPVASLALLIAITLFVRKKSKGNVE
CCCCCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA