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The map label for this gene is ykgC [H]

Identifier: 15926272

GI number: 15926272

Start: 644319

End: 645767

Strand: Reverse

Name: ykgC [H]

Synonym: SA0551

Alternate gene names: 15926272

Gene position: 645767-644319 (Counterclockwise)

Preceding gene: 15926273

Following gene: 15926265

Centisome position: 22.94

GC content: 34.16

Gene sequence:

>1449_bases
TTGCTCGTAATATTGCAACTACCATGTCACATTATCAGCAAGACGAACAGAATATCATTATTAATTTTTATAATGAAAAA
ACAATCAAAGATGTCATTGAAGACATTCAAAAGGAGGATTTATGTCATGAAAACATATGATTTAATTGTAATAGGATTTG
GGAAAGCTGGTAAAACTTTAGCGAAATATGCTGCATCAACAGGTCAACACGTCGCAGTTATCGAACAATCTTCGAAAATG
TATGGCGGCACTTGTATAAATATAGGATGTATACCTTCGAAGACACTTGTACATGATGGATTAGAAGGCAAATCTTTTGA
AGCAAGTTATAACCGTAAAAACGATGTTGTCAATGCGCTAAACAATAAAAATTACCACTTATTAGCAGACGATAACAACA
TTGATGTATTGGATTTTAAAGCGCAGTTTAAATCTAATACTGAAGTGAATTTATTAGATCAGCATGGCGATATCGTCGAT
AGTATTACTGCACCTCATATCATTATTAATACCGGTGCTACCTCTATCATTCCTAACATAAAAGGCCTTGATCAAGCTAA
ACATGTCTTCGATTCAACAGGTTTATTAAACATTAGCTATCAACCTAAGCATCTCGTTATTGTAGGTGGCGGTTATATTG
CCTTAGAATTTGCTTCAATGTTTGCGAATTTAGGTAGTAAGGTAACAGTATTAGAACGTGGTGAATCATTTATGCCACGC
GAAGATCAAGATGTCGTTGCACATGCTATTACTGACTTAGAAAATAAAGGCATTGCATTGCATACAAATGTTGAAACGAC
TGAATTGTCATCTGACGATCATCATACAACAGTCCGTACTAATGTTGGCAACTTTGAGGCTGATGCAGTACTTTTGGCTA
TCGGGCGCAAACCGAATACAGCCTTAGCTTTAGAAAATACTGATATCGAATTAGGTGATAGAGGCGAAATTAAAGTCAAT
GCTCAACTTCAAACATCTGTGCCACATATTTATGCTGCAGGTGATGTTAAAGGCGGACTTCAATTTACGTATATATCTTT
AGATGATTATCGAATTATCAAATCAGCGTTATATGGTAATCAGTCACGTACGACTGACAATAGAGGTAGCGTGCCTTATA
CAGTATTTATAGATCCACCATTATCACGTGTTGGATTAACTAGTAAAGAAGCTGCCGCTCAACATTATGATTACACTGAA
CATCAACTTTTAGTAAGTGCTATACCTCGTCACAAAATTAACAATGATCCAAGAGGTTTATTTAAAGTAGTCATTAATAA
TGAAAATAATATGATTTTAGGTGCTACATTATATGGTAAGCAATCTGAAGAATTAATTAATATAATTAAACTTGCGATTG
ATCAAAACATTCCATATACCGTATTACGAGATAATATTTATACACATCCTACGATGGCCGAATCATTTAATGATTTATTT
AATTTCTAG

Upstream 100 bases:

>100_bases
AGTGCTGATGTCTCTCTAGCAACATTATATAAACATTTTGTCTTAGAGAAAGAACACCACACACGTCTATTTACTGGCGA
CGAAGGCAGTCACTGTCAAA

Downstream 100 bases:

>100_bases
ACAAAACATAAAAACCTGGTGGCACGCATTGAATGATGCTGCCATCAGGTTTTATTGTTGTGCTTTTCGCTTTTCTAATT
TTTCTTTAAGCTTTCTATCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 482

Protein sequence:

>482_residues
MLVILQLPCHIISKTNRISLLIFIMKKQSKMSLKTFKRRIYVMKTYDLIVIGFGKAGKTLAKYAASTGQHVAVIEQSSKM
YGGTCINIGCIPSKTLVHDGLEGKSFEASYNRKNDVVNALNNKNYHLLADDNNIDVLDFKAQFKSNTEVNLLDQHGDIVD
SITAPHIIINTGATSIIPNIKGLDQAKHVFDSTGLLNISYQPKHLVIVGGGYIALEFASMFANLGSKVTVLERGESFMPR
EDQDVVAHAITDLENKGIALHTNVETTELSSDDHHTTVRTNVGNFEADAVLLAIGRKPNTALALENTDIELGDRGEIKVN
AQLQTSVPHIYAAGDVKGGLQFTYISLDDYRIIKSALYGNQSRTTDNRGSVPYTVFIDPPLSRVGLTSKEAAAQHYDYTE
HQLLVSAIPRHKINNDPRGLFKVVINNENNMILGATLYGKQSEELINIIKLAIDQNIPYTVLRDNIYTHPTMAESFNDLF
NF

Sequences:

>Translated_482_residues
MLVILQLPCHIISKTNRISLLIFIMKKQSKMSLKTFKRRIYVMKTYDLIVIGFGKAGKTLAKYAASTGQHVAVIEQSSKM
YGGTCINIGCIPSKTLVHDGLEGKSFEASYNRKNDVVNALNNKNYHLLADDNNIDVLDFKAQFKSNTEVNLLDQHGDIVD
SITAPHIIINTGATSIIPNIKGLDQAKHVFDSTGLLNISYQPKHLVIVGGGYIALEFASMFANLGSKVTVLERGESFMPR
EDQDVVAHAITDLENKGIALHTNVETTELSSDDHHTTVRTNVGNFEADAVLLAIGRKPNTALALENTDIELGDRGEIKVN
AQLQTSVPHIYAAGDVKGGLQFTYISLDDYRIIKSALYGNQSRTTDNRGSVPYTVFIDPPLSRVGLTSKEAAAQHYDYTE
HQLLVSAIPRHKINNDPRGLFKVVINNENNMILGATLYGKQSEELINIIKLAIDQNIPYTVLRDNIYTHPTMAESFNDLF
NF
>Mature_482_residues
MLVILQLPCHIISKTNRISLLIFIMKKQSKMSLKTFKRRIYVMKTYDLIVIGFGKAGKTLAKYAASTGQHVAVIEQSSKM
YGGTCINIGCIPSKTLVHDGLEGKSFEASYNRKNDVVNALNNKNYHLLADDNNIDVLDFKAQFKSNTEVNLLDQHGDIVD
SITAPHIIINTGATSIIPNIKGLDQAKHVFDSTGLLNISYQPKHLVIVGGGYIALEFASMFANLGSKVTVLERGESFMPR
EDQDVVAHAITDLENKGIALHTNVETTELSSDDHHTTVRTNVGNFEADAVLLAIGRKPNTALALENTDIELGDRGEIKVN
AQLQTSVPHIYAAGDVKGGLQFTYISLDDYRIIKSALYGNQSRTTDNRGSVPYTVFIDPPLSRVGLTSKEAAAQHYDYTE
HQLLVSAIPRHKINNDPRGLFKVVINNENNMILGATLYGKQSEELINIIKLAIDQNIPYTVLRDNIYTHPTMAESFNDLF
NF

Specific function: Unknown

COG id: COG1249

COG function: function code C; Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI91199540, Length=462, Percent_Identity=27.4891774891775, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI50301238, Length=466, Percent_Identity=27.2532188841202, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI22035672, Length=481, Percent_Identity=27.4428274428274, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI148277065, Length=464, Percent_Identity=25.6465517241379, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI33519430, Length=464, Percent_Identity=25.6465517241379, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI33519428, Length=464, Percent_Identity=25.6465517241379, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI33519426, Length=464, Percent_Identity=25.6465517241379, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI291045266, Length=463, Percent_Identity=25.0539956803456, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI148277071, Length=464, Percent_Identity=25.6465517241379, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI291045268, Length=459, Percent_Identity=23.3115468409586, Blast_Score=95, Evalue=2e-19,
Organism=Escherichia coli, GI87081717, Length=441, Percent_Identity=49.2063492063492, Blast_Score=418, Evalue=1e-118,
Organism=Escherichia coli, GI1786307, Length=453, Percent_Identity=28.0353200883002, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI87082354, Length=455, Percent_Identity=28.3516483516484, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI1789915, Length=439, Percent_Identity=27.3348519362187, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1787114, Length=190, Percent_Identity=28.9473684210526, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI32565766, Length=458, Percent_Identity=29.2576419213974, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17557007, Length=496, Percent_Identity=28.8306451612903, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71983419, Length=465, Percent_Identity=27.5268817204301, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71983429, Length=465, Percent_Identity=27.5268817204301, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71982272, Length=489, Percent_Identity=24.5398773006135, Blast_Score=107, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6321091, Length=484, Percent_Identity=27.0661157024793, Blast_Score=154, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6325166, Length=494, Percent_Identity=26.9230769230769, Blast_Score=149, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6325240, Length=469, Percent_Identity=27.0788912579957, Blast_Score=122, Evalue=9e-29,
Organism=Drosophila melanogaster, GI21358499, Length=464, Percent_Identity=29.5258620689655, Blast_Score=165, Evalue=8e-41,
Organism=Drosophila melanogaster, GI24640553, Length=478, Percent_Identity=28.4518828451883, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24640549, Length=478, Percent_Identity=28.4518828451883, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24640551, Length=478, Percent_Identity=28.4518828451883, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI17737741, Length=482, Percent_Identity=26.3485477178423, Blast_Score=113, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR012999
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: NA

Molecular weight: Translated: 53320; Mature: 53320

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: PS00076 PYRIDINE_REDOX_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVILQLPCHIISKTNRISLLIFIMKKQSKMSLKTFKRRIYVMKTYDLIVIGFGKAGKTL
CEEEEECCHHHHCCCCCEEEEEEEEECCCCHHHHHHHCEEEEEEEEEEEEEEECCCCHHH
AKYAASTGQHVAVIEQSSKMYGGTCINIGCIPSKTLVHDGLEGKSFEASYNRKNDVVNAL
HHHHHCCCCEEEEEECCCCCCCCEEEEEECCCCHHHHHCCCCCCCEECCCCCCHHHHHHH
NNKNYHLLADDNNIDVLDFKAQFKSNTEVNLLDQHGDIVDSITAPHIIINTGATSIIPNI
CCCCEEEEECCCCEEEEEEEECCCCCCEEEEECCCCCCHHHCCCCEEEEECCCHHCCCCC
KGLDQAKHVFDSTGLLNISYQPKHLVIVGGGYIALEFASMFANLGSKVTVLERGESFMPR
CCCHHHHHHHCCCCEEEEEECCCEEEEECCCEEEHHHHHHHHHCCCEEEEEECCCCCCCC
EDQDVVAHAITDLENKGIALHTNVETTELSSDDHHTTVRTNVGNFEADAVLLAIGRKPNT
CCHHHHHHHHHHHCCCCEEEEECCCEEECCCCCCCEEEEECCCCCCCCEEEEEECCCCCE
ALALENTDIELGDRGEIKVNAQLQTSVPHIYAAGDVKGGLQFTYISLDDYRIIKSALYGN
EEEEECCCEEECCCCCEEEEEEEECCCCEEEEECCCCCCEEEEEEECCCHHHHHHHHCCC
QSRTTDNRGSVPYTVFIDPPLSRVGLTSKEAAAQHYDYTEHQLLVSAIPRHKINNDPRGL
CCCCCCCCCCCCEEEEECCCHHHHCCCCHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCEE
FKVVINNENNMILGATLYGKQSEELINIIKLAIDQNIPYTVLRDNIYTHPTMAESFNDLF
EEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHH
NF
CC
>Mature Secondary Structure
MLVILQLPCHIISKTNRISLLIFIMKKQSKMSLKTFKRRIYVMKTYDLIVIGFGKAGKTL
CEEEEECCHHHHCCCCCEEEEEEEEECCCCHHHHHHHCEEEEEEEEEEEEEEECCCCHHH
AKYAASTGQHVAVIEQSSKMYGGTCINIGCIPSKTLVHDGLEGKSFEASYNRKNDVVNAL
HHHHHCCCCEEEEEECCCCCCCCEEEEEECCCCHHHHHCCCCCCCEECCCCCCHHHHHHH
NNKNYHLLADDNNIDVLDFKAQFKSNTEVNLLDQHGDIVDSITAPHIIINTGATSIIPNI
CCCCEEEEECCCCEEEEEEEECCCCCCEEEEECCCCCCHHHCCCCEEEEECCCHHCCCCC
KGLDQAKHVFDSTGLLNISYQPKHLVIVGGGYIALEFASMFANLGSKVTVLERGESFMPR
CCCHHHHHHHCCCCEEEEEECCCEEEEECCCEEEHHHHHHHHHCCCEEEEEECCCCCCCC
EDQDVVAHAITDLENKGIALHTNVETTELSSDDHHTTVRTNVGNFEADAVLLAIGRKPNT
CCHHHHHHHHHHHCCCCEEEEECCCEEECCCCCCCEEEEECCCCCCCCEEEEEECCCCCE
ALALENTDIELGDRGEIKVNAQLQTSVPHIYAAGDVKGGLQFTYISLDDYRIIKSALYGN
EEEEECCCEEECCCCCEEEEEEEECCCCEEEEECCCCCCEEEEEEECCCHHHHHHHHCCC
QSRTTDNRGSVPYTVFIDPPLSRVGLTSKEAAAQHYDYTEHQLLVSAIPRHKINNDPRGL
CCCCCCCCCCCCEEEEECCCHHHHCCCCHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCEE
FKVVINNENNMILGATLYGKQSEELINIIKLAIDQNIPYTVLRDNIYTHPTMAESFNDLF
EEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHH
NF
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FAD. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]