Click here to switch to the map view.

The map label for this gene is nusG

Identifier: 15926213

GI number: 15926213

Start: 575388

End: 575936

Strand: Direct

Name: nusG

Synonym: SA0494

Alternate gene names: 15926213

Gene position: 575388-575936 (Clockwise)

Preceding gene: 15926212

Following gene: 15926215

Centisome position: 20.44

GC content: 35.52

Gene sequence:

>549_bases
ATGTCTGAAGAAGTTGGCGCAAAGCGTTGGTATGCAGTGCATACATATTCTGGATATGAAAATAAAGTTAAAAAGAATTT
AGAAAAAAGAGTAGAATCTATGAATATGACTGAACAAATCTTTAGAGTAGTCATACCGGAAGAAGAAGAAACTCAAGTAA
AAGATGGCAAAGCTAAAACGACTGTTAAAAAAACATTCCCTGGATATGTTTTAGTGGAATTAATCATGACAGATGAATCA
TGGTATGTGGTAAGAAATACACCAGGCGTTACTGGTTTTGTAGGTTCTGCAGGTGCAGGGTCTAAGCCAAATCCATTGTT
ACCAGAAGAAGTTCGCTTCATCTTAAAACAAATGGGTCTTAAAGAAAAGACTATCGATGTTGAACTCGAAGTTGGCGAGC
AAGTTCGTATTAAATCAGGTCCATTTGCGAATCAAGTTGGTGAAGTTCAAGAAATTGAAACAGATAAGTTTAAGCTAACA
GTATTAGTAGATATGTTTGGCCGAGAAACACCAGTAGAAGTTGAATTCGATCAAATAGAAAAGCTTTAA

Upstream 100 bases:

>100_bases
TGTAGTTTCTACTGTTATATTCTTCTTAGTCTTTTTCTATGCCTTAGATTTAGGAATTACAGCATTGAAAAATTTATTAT
TTGGTTAGAGGAGTGAAGAC

Downstream 100 bases:

>100_bases
TTAACAATTAAAGTTATTAAACTAACCAAAAGATAAAAAAGAGTATTGATTTTTTAATTAGAAAAGTGTTAAAATTATGT
GGTCGCGCTTTTAGAGCGCC

Product: transcription antitermination protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 182; Mature: 181

Protein sequence:

>182_residues
MSEEVGAKRWYAVHTYSGYENKVKKNLEKRVESMNMTEQIFRVVIPEEEETQVKDGKAKTTVKKTFPGYVLVELIMTDES
WYVVRNTPGVTGFVGSAGAGSKPNPLLPEEVRFILKQMGLKEKTIDVELEVGEQVRIKSGPFANQVGEVQEIETDKFKLT
VLVDMFGRETPVEVEFDQIEKL

Sequences:

>Translated_182_residues
MSEEVGAKRWYAVHTYSGYENKVKKNLEKRVESMNMTEQIFRVVIPEEEETQVKDGKAKTTVKKTFPGYVLVELIMTDES
WYVVRNTPGVTGFVGSAGAGSKPNPLLPEEVRFILKQMGLKEKTIDVELEVGEQVRIKSGPFANQVGEVQEIETDKFKLT
VLVDMFGRETPVEVEFDQIEKL
>Mature_181_residues
SEEVGAKRWYAVHTYSGYENKVKKNLEKRVESMNMTEQIFRVVIPEEEETQVKDGKAKTTVKKTFPGYVLVELIMTDESW
YVVRNTPGVTGFVGSAGAGSKPNPLLPEEVRFILKQMGLKEKTIDVELEVGEQVRIKSGPFANQVGEVQEIETDKFKLTV
LVDMFGRETPVEVEFDQIEKL

Specific function: Influences transcription termination and antitermination. Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase

COG id: COG0250

COG function: function code K; Transcription antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KOW domain

Homologues:

Organism=Escherichia coli, GI1790414, Length=181, Percent_Identity=40.8839779005525, Blast_Score=145, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUSG_STAA8 (Q2G0P2)

Other databases:

- EMBL:   U96619
- EMBL:   CP000253
- RefSeq:   YP_499090.1
- ProteinModelPortal:   Q2G0P2
- SMR:   Q2G0P2
- STRING:   Q2G0P2
- EnsemblBacteria:   EBSTAT00000029839
- GeneID:   3920371
- GenomeReviews:   CP000253_GR
- KEGG:   sao:SAOUHSC_00517
- eggNOG:   COG0250
- GeneTree:   EBGT00050000024592
- HOGENOM:   HBG751162
- OMA:   GVERPKP
- ProtClustDB:   CLSK884716
- BioCyc:   SAUR93061:SAOUHSC_00517-MONOMER
- InterPro:   IPR005824
- InterPro:   IPR001062
- InterPro:   IPR015869
- InterPro:   IPR006645
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.30.30.30
- Gene3D:   G3DSA:3.30.70.940
- PRINTS:   PR00338
- SMART:   SM00739
- SMART:   SM00738
- TIGRFAMs:   TIGR00922

Pfam domain/function: PF00467 KOW; PF02357 NusG; SSF82679 Transcrpt_antiterm_NusG_N; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20664; Mature: 20533

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS01014 NUSG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEEVGAKRWYAVHTYSGYENKVKKNLEKRVESMNMTEQIFRVVIPEEEETQVKDGKAKT
CCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCHH
TVKKTFPGYVLVELIMTDESWYVVRNTPGVTGFVGSAGAGSKPNPLLPEEVRFILKQMGL
HHHHHCCCEEEEEEEEECCCEEEEECCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHCCC
KEKTIDVELEVGEQVRIKSGPFANQVGEVQEIETDKFKLTVLVDMFGRETPVEVEFDQIE
CCCEEEEEEECCCEEEECCCCCHHHCCCHHHCCCCCEEEEEEEEECCCCCCCEEEHHHHH
KL
CC
>Mature Secondary Structure 
SEEVGAKRWYAVHTYSGYENKVKKNLEKRVESMNMTEQIFRVVIPEEEETQVKDGKAKT
CCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCHH
TVKKTFPGYVLVELIMTDESWYVVRNTPGVTGFVGSAGAGSKPNPLLPEEVRFILKQMGL
HHHHHCCCEEEEEEEEECCCEEEEECCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHCCC
KEKTIDVELEVGEQVRIKSGPFANQVGEVQEIETDKFKLTVLVDMFGRETPVEVEFDQIE
CCCEEEEEEECCCEEEECCCCCHHHCCCHHHCCCCCEEEEEEEEECCCCCCCEEEHHHHH
KL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA