BacMap

Definition	Staphylococcus aureus subsp. aureus N315, complete genome.
Accession	NC_002745
Length	2,814,816

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The map label for this gene is srtF [H]

Identifier: 15926052

GI number: 15926052

Start: 395586

End: 396428

Strand: Direct

Name: srtF [H]

Synonym: SA0339

Alternate gene names: 15926052

Gene position: 395586-396428 (Clockwise)

Preceding gene: 15926051

Following gene: 15926053

Centisome position: 14.05

GC content: 31.79

Gene sequence:

>843_bases
ATGACAACATTGTTAAACGTAGATCGTGTGAACAAACAATACAAAGATTCGGATTTTAAATTGCAAGATGCATCTTTAAC
GATTTCTACTAATGAGACAGTTGGATTAATTGGGAAAAATGGCTCAGGTAAATCGACATTAATTAATATTCTAGTAGGCA
ATCGACATAAAGATAACGGTAGTATTGCATTTTTTGGAGAAGAACATGCTGCGGATGATGTCGAATATAAAGAACACATA
GGTGTTGTGTTTGATGATCTGAGAGTACCTAATAAATTGACTATTAAAGATATTGATAAAGTATTTCAATCTATTTATAC
GACTTGGAATAGTCAAAAATTCTTTGATTTAATCAAATATTTCGAGTTACCACTACAAACTAAAATTAAAACTTTTTCAA
GAGGGATGCGAATGAAGATAGCTTTAACGATTGCGCTTTCTCATGATGTGAAGTTATTAATCTTAGATGAAGCAACTGCA
GGTATGGATGTTTCTGGAAGAGAAGAAGTAATGGAACTATTAGAAGATTTTGTCGCTCAAGGTGGAGGCATCTTAATATC
ATCGCATATTTCTGAAGATATAGAACAATTAGCGGATAAATTAGTGTTTATGAAAGATGGACGAATGATTTTAACTGAAC
AGAAAGATATACTTTTAGCACAATATGGAATTGTTACGACAGGAGATAAAGATGTTGAAATTCCTAAGCATTTAATCATT
GCTTCTAGATTGTCAAAGGGGAAATATCAAATTTTAGTTAAAGATTATGCAGAAATTGAAAATGCAGAGCCTTTAAAACA
CATTGATGACGCTACGAAAATCATAATGCGAGGTGAAGTATAA

Upstream 100 bases:

>100_bases
TAGTTTGCTACTTATCATTGCTATTTTCATATATAACGCCTTTAGCTATTTATTGAAGAGAAGACGTTTTTATTAAAATT
AAACAAAGAGGAGCATGGAT

Downstream 100 bases:

>100_bases
TGAAAGGTATGTTCCTAAGTAGTTTTTATGCAACGAGAAAGCAAACATATATTTATTTTATAGTCGCTATCATAGCTGCG
GGATACTTTGCAGTATTTAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MTTLLNVDRVNKQYKDSDFKLQDASLTISTNETVGLIGKNGSGKSTLINILVGNRHKDNGSIAFFGEEHAADDVEYKEHI
GVVFDDLRVPNKLTIKDIDKVFQSIYTTWNSQKFFDLIKYFELPLQTKIKTFSRGMRMKIALTIALSHDVKLLILDEATA
GMDVSGREEVMELLEDFVAQGGGILISSHISEDIEQLADKLVFMKDGRMILTEQKDILLAQYGIVTTGDKDVEIPKHLII
ASRLSKGKYQILVKDYAEIENAEPLKHIDDATKIIMRGEV

Sequences:

>Translated_280_residues
MTTLLNVDRVNKQYKDSDFKLQDASLTISTNETVGLIGKNGSGKSTLINILVGNRHKDNGSIAFFGEEHAADDVEYKEHI
GVVFDDLRVPNKLTIKDIDKVFQSIYTTWNSQKFFDLIKYFELPLQTKIKTFSRGMRMKIALTIALSHDVKLLILDEATA
GMDVSGREEVMELLEDFVAQGGGILISSHISEDIEQLADKLVFMKDGRMILTEQKDILLAQYGIVTTGDKDVEIPKHLII
ASRLSKGKYQILVKDYAEIENAEPLKHIDDATKIIMRGEV
>Mature_279_residues
TTLLNVDRVNKQYKDSDFKLQDASLTISTNETVGLIGKNGSGKSTLINILVGNRHKDNGSIAFFGEEHAADDVEYKEHIG
VVFDDLRVPNKLTIKDIDKVFQSIYTTWNSQKFFDLIKYFELPLQTKIKTFSRGMRMKIALTIALSHDVKLLILDEATAG
MDVSGREEVMELLEDFVAQGGGILISSHISEDIEQLADKLVFMKDGRMILTEQKDILLAQYGIVTTGDKDVEIPKHLIIA
SRLSKGKYQILVKDYAEIENAEPLKHIDDATKIIMRGEV

Specific function: Implicated in the export process of the lantibiotic SrtA (Potential) [H]

COG id: COG1131

COG function: function code V; ABC-type multidrug transport system, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI45446740, Length=223, Percent_Identity=26.9058295964126, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI47078218, Length=223, Percent_Identity=26.9058295964126, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI31657092, Length=211, Percent_Identity=25.5924170616114, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI116734710, Length=215, Percent_Identity=26.5116279069767, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI27262624, Length=216, Percent_Identity=29.1666666666667, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI27262626, Length=216, Percent_Identity=29.1666666666667, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI153792144, Length=221, Percent_Identity=28.5067873303167, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI255708477, Length=214, Percent_Identity=29.9065420560748, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI6005701, Length=195, Percent_Identity=23.0769230769231, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI9955963, Length=231, Percent_Identity=24.2424242424242, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI27477115, Length=191, Percent_Identity=23.0366492146597, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI21536376, Length=231, Percent_Identity=25.1082251082251, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI30795238, Length=210, Percent_Identity=23.8095238095238, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI27881501, Length=180, Percent_Identity=25.5555555555556, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1786319, Length=226, Percent_Identity=28.3185840707965, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789891, Length=233, Percent_Identity=28.3261802575107, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788472, Length=228, Percent_Identity=27.1929824561404, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI48995001, Length=200, Percent_Identity=24.5, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787792, Length=214, Percent_Identity=28.0373831775701, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789991, Length=226, Percent_Identity=26.1061946902655, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI48994943, Length=202, Percent_Identity=24.7524752475248, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787105, Length=223, Percent_Identity=25.5605381165919, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87081782, Length=190, Percent_Identity=26.8421052631579, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87082268, Length=232, Percent_Identity=25.8620689655172, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1787759, Length=212, Percent_Identity=26.8867924528302, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1788540, Length=218, Percent_Identity=27.5229357798165, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790190, Length=221, Percent_Identity=23.0769230769231, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788210, Length=209, Percent_Identity=27.7511961722488, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI48994883, Length=231, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1786654, Length=177, Percent_Identity=29.9435028248588, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788897, Length=214, Percent_Identity=24.7663551401869, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1786398, Length=227, Percent_Identity=24.6696035242291, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790739, Length=205, Percent_Identity=22.9268292682927, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1786803, Length=206, Percent_Identity=24.2718446601942, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17510237, Length=218, Percent_Identity=27.5229357798165, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI115533608, Length=229, Percent_Identity=27.0742358078603, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71983516, Length=193, Percent_Identity=27.979274611399, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71983510, Length=193, Percent_Identity=27.979274611399, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71983523, Length=193, Percent_Identity=27.979274611399, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI193211017, Length=214, Percent_Identity=25.7009345794392, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193211015, Length=214, Percent_Identity=25.7009345794392, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71996809, Length=214, Percent_Identity=25.7009345794392, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281362751, Length=219, Percent_Identity=25.1141552511416, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24650853, Length=219, Percent_Identity=25.1141552511416, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24650855, Length=219, Percent_Identity=25.1141552511416, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI85725262, Length=226, Percent_Identity=27.4336283185841, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI221500365, Length=225, Percent_Identity=25.7777777777778, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI116007184, Length=225, Percent_Identity=25.7777777777778, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24666092, Length=214, Percent_Identity=28.0373831775701, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28574150, Length=205, Percent_Identity=27.3170731707317, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24582014, Length=209, Percent_Identity=24.8803827751196, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24582012, Length=209, Percent_Identity=24.8803827751196, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI116007328, Length=205, Percent_Identity=27.3170731707317, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI221512771, Length=210, Percent_Identity=26.1904761904762, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI28573573, Length=193, Percent_Identity=29.0155440414508, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28573571, Length=193, Percent_Identity=29.0155440414508, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24643674, Length=205, Percent_Identity=26.3414634146341, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR022501
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 31465; Mature: 31333

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLLNVDRVNKQYKDSDFKLQDASLTISTNETVGLIGKNGSGKSTLINILVGNRHKDNG
CCEEECHHHHCHHHCCCCCEEECCEEEEECCCEEEEEECCCCCCCEEEEEEECCCCCCCC
SIAFFGEEHAADDVEYKEHIGVVFDDLRVPNKLTIKDIDKVFQSIYTTWNSQKFFDLIKY
CEEEEECCCCCCCCCHHHHCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
FELPLQTKIKTFSRGMRMKIALTIALSHDVKLLILDEATAGMDVSGREEVMELLEDFVAQ
HCCCHHHHHHHHHCCCEEEEEEEEEECCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHC
GGGILISSHISEDIEQLADKLVFMKDGRMILTEQKDILLAQYGIVTTGDKDVEIPKHLII
CCCEEEEHHHHHHHHHHHHHEEEEECCCEEEECCCCEEEEECCEEECCCCCCCCCHHHHH
ASRLSKGKYQILVKDYAEIENAEPLKHIDDATKIIMRGEV
HHHCCCCCEEEEEEEHHHCCCCCCHHHHHHHHEEEEECCC
>Mature Secondary Structure 
TTLLNVDRVNKQYKDSDFKLQDASLTISTNETVGLIGKNGSGKSTLINILVGNRHKDNG
CEEECHHHHCHHHCCCCCEEECCEEEEECCCEEEEEECCCCCCCEEEEEEECCCCCCCC
SIAFFGEEHAADDVEYKEHIGVVFDDLRVPNKLTIKDIDKVFQSIYTTWNSQKFFDLIKY
CEEEEECCCCCCCCCHHHHCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHH
FELPLQTKIKTFSRGMRMKIALTIALSHDVKLLILDEATAGMDVSGREEVMELLEDFVAQ
HCCCHHHHHHHHHCCCEEEEEEEEEECCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHC
GGGILISSHISEDIEQLADKLVFMKDGRMILTEQKDILLAQYGIVTTGDKDVEIPKHLII
CCCEEEEHHHHHHHHHHHHHEEEEECCCEEEECCCCEEEEECCEEECCCCCCCCCHHHHH
ASRLSKGKYQILVKDYAEIENAEPLKHIDDATKIIMRGEV
HHHCCCCCEEEEEEEHHHCCCCCCHHHHHHHHEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]