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The map label for this gene is yfeV [C]

Identifier: 15925896

GI number: 15925896

Start: 219407

End: 220861

Strand: Direct

Name: yfeV [C]

Synonym: SA0186

Alternate gene names: 15925896

Gene position: 219407-220861 (Clockwise)

Preceding gene: 15925895

Following gene: 15925897

Centisome position: 7.79

GC content: 37.87

Gene sequence:

>1455_bases
ATGACCAAAGAACAACAACTTGCAGAACGAATTATTGCTGCAGTAGGTGGTATGGATAATATAGATAGTGTCATGAACTG
CATGACACGTGTGCGTATTAAAGTATTAGATGAAAATAAAGTAGATGACCAAGAACTAAGGCATATTGATGGTGTCATGG
GTGTTATACACGATGAACGCATTCAAGTTGTGGTTGGACCTGGTACAGTCAATAAAGTGGCTAATCATATGGCGGAATTA
AGTGGTGTTAAACTAGGTGACCCAATACCACACCATCACAATGATAGTGAAAAAATGGACTATAAATCATATGCAGCTGA
TAAAGCAAAGGCGAATAAAGAAGCACATAAAGCAAAACAAAAGAATGGTAAGTTGAATAAAGTATTGAAATCAATTGCCA
ATATCTTTATACCGTTGATTCCTGCATTTATTGGAGCTGGATTAATTGGTGGTATTGCAGCAGTACTGAGTAACTTAATG
GTGGCAGGCTATATTTCAGGTGCTTGGATTACGCAACTTATAACAGTATTCAATGTCATTAAAGACGGTATGTTAGCATA
CTTAGCTATTTTTACTGGTATTAATGCGGCTAAAGAATTTGGTGCAACACCAGGACTTGGTGGCGTGATTGGTGGTACAA
CGTTATTAACGGGTATTGCTGGTAAAAATATTTTAATGAATGTCTTCACTGGAGAACCATTGCAACCTGGACAAGGTGGA
ATTATTGGCGTTATTTTTGCCGTTTGGATTTTAAGTATTGTCGAAAAGAGATTGCATAAAATTGTGCCAAATGCGATTGA
TATTATTGTAACGCCGACTATTGCATTGTTGATTGTAGGACTATTAACTATCTTTATCTTTATGCCATTAGCAGGTTTTG
TTTCAGACAGTTTAGTTTCAGTAGTTAACGGAATTATTAGTATTGGTGGCGTATTTAGTGGATTTATCATTGGAGCAAGC
TTCCTACCGTTAGTTATGTTAGGGCTTCATCATATTTTTACGCCAATTCATATAGAAATGATTAACCAATCTGGTGCTAC
TTACTTATTGCCAATTGCAGCGATGGCTGGTGCTGGACAAGTAGGTGCCGCATTAGCACTTTGGGTAAGATGTAAACGCA
ACACAACATTACGTAATACTTTAAAAGGTGCATTGCCAGTTGGTTTCCTAGGTATCGGAGAACCATTAATCTATGGTGTG
ACTTTGCCATTAGGTCGACCTTTCTTAACTGCTTGTATTGGTGGTGGTATTGGTGGCGCTGTAATAGGTGGAATTGGACA
TATTGGTGCCAAAGCAATAGGCCCAAGTGGTGTGTCACTCTTACCATTAATCTCAGATAATATGTATTTAGGTTATATTG
CAGGATTACTTGCTGCATATGCTGGTGGATTCGTTTGTACATATTTATTTGGAACGACAAAGGCGATGCGACAGACAGAT
TTGTTGGGTGATTAA

Upstream 100 bases:

>100_bases
TGTGTGGCATTTCTAAGGAAGAAGCAACAAGACGGTTATTAAACAATGGTGACATTGTTAAACGAGCAATCAGAGATAGA
CAACCTTAGGAGGGATTTAA

Downstream 100 bases:

>100_bases
TGATGACAAATATTTTATATCGCATTGATAAACAGTTGAGTGATTTTACGAAGACAGAAAAGATAATCGCTGATTACATT
TTAAAGAATCCACATAAAAT

Product: hypothetical protein

Products: NA

Alternate protein names: Phosphotransferase enzyme IIB component; PTS system EIIB component; Permease IIC component; PTS system EIIC component

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MTKEQQLAERIIAAVGGMDNIDSVMNCMTRVRIKVLDENKVDDQELRHIDGVMGVIHDERIQVVVGPGTVNKVANHMAEL
SGVKLGDPIPHHHNDSEKMDYKSYAADKAKANKEAHKAKQKNGKLNKVLKSIANIFIPLIPAFIGAGLIGGIAAVLSNLM
VAGYISGAWITQLITVFNVIKDGMLAYLAIFTGINAAKEFGATPGLGGVIGGTTLLTGIAGKNILMNVFTGEPLQPGQGG
IIGVIFAVWILSIVEKRLHKIVPNAIDIIVTPTIALLIVGLLTIFIFMPLAGFVSDSLVSVVNGIISIGGVFSGFIIGAS
FLPLVMLGLHHIFTPIHIEMINQSGATYLLPIAAMAGAGQVGAALALWVRCKRNTTLRNTLKGALPVGFLGIGEPLIYGV
TLPLGRPFLTACIGGGIGGAVIGGIGHIGAKAIGPSGVSLLPLISDNMYLGYIAGLLAAYAGGFVCTYLFGTTKAMRQTD
LLGD

Sequences:

>Translated_484_residues
MTKEQQLAERIIAAVGGMDNIDSVMNCMTRVRIKVLDENKVDDQELRHIDGVMGVIHDERIQVVVGPGTVNKVANHMAEL
SGVKLGDPIPHHHNDSEKMDYKSYAADKAKANKEAHKAKQKNGKLNKVLKSIANIFIPLIPAFIGAGLIGGIAAVLSNLM
VAGYISGAWITQLITVFNVIKDGMLAYLAIFTGINAAKEFGATPGLGGVIGGTTLLTGIAGKNILMNVFTGEPLQPGQGG
IIGVIFAVWILSIVEKRLHKIVPNAIDIIVTPTIALLIVGLLTIFIFMPLAGFVSDSLVSVVNGIISIGGVFSGFIIGAS
FLPLVMLGLHHIFTPIHIEMINQSGATYLLPIAAMAGAGQVGAALALWVRCKRNTTLRNTLKGALPVGFLGIGEPLIYGV
TLPLGRPFLTACIGGGIGGAVIGGIGHIGAKAIGPSGVSLLPLISDNMYLGYIAGLLAAYAGGFVCTYLFGTTKAMRQTD
LLGD
>Mature_483_residues
TKEQQLAERIIAAVGGMDNIDSVMNCMTRVRIKVLDENKVDDQELRHIDGVMGVIHDERIQVVVGPGTVNKVANHMAELS
GVKLGDPIPHHHNDSEKMDYKSYAADKAKANKEAHKAKQKNGKLNKVLKSIANIFIPLIPAFIGAGLIGGIAAVLSNLMV
AGYISGAWITQLITVFNVIKDGMLAYLAIFTGINAAKEFGATPGLGGVIGGTTLLTGIAGKNILMNVFTGEPLQPGQGGI
IGVIFAVWILSIVEKRLHKIVPNAIDIIVTPTIALLIVGLLTIFIFMPLAGFVSDSLVSVVNGIISIGGVFSGFIIGASF
LPLVMLGLHHIFTPIHIEMINQSGATYLLPIAAMAGAGQVGAALALWVRCKRNTTLRNTLKGALPVGFLGIGEPLIYGVT
LPLGRPFLTACIGGGIGGAVIGGIGHIGAKAIGPSGVSLLPLISDNMYLGYIAGLLAAYAGGFVCTYLFGTTKAMRQTDL
LGD

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain

Homologues:

Organism=Escherichia coli, GI1788769, Length=489, Percent_Identity=37.2188139059305, Blast_Score=258, Evalue=7e-70,
Organism=Escherichia coli, GI1790159, Length=432, Percent_Identity=29.3981481481481, Blast_Score=168, Evalue=8e-43,
Organism=Escherichia coli, GI48994906, Length=432, Percent_Identity=29.1666666666667, Blast_Score=139, Evalue=6e-34,
Organism=Escherichia coli, GI2367362, Length=467, Percent_Identity=26.9807280513919, Blast_Score=124, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PTXBC_STAA3 (Q2FK70)

Other databases:

- EMBL:   CP000255
- RefSeq:   YP_492908.1
- ProteinModelPortal:   Q2FK70
- SMR:   Q2FK70
- STRING:   Q2FK70
- EnsemblBacteria:   EBSTAT00000036287
- GeneID:   3913839
- GenomeReviews:   CP000255_GR
- KEGG:   saa:SAUSA300_0194
- eggNOG:   COG1263
- GeneTree:   EBGT00050000023801
- HOGENOM:   HBG673521
- OMA:   RTQIKGA
- ProtClustDB:   CLSK884466
- InterPro:   IPR018113
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- Gene3D:   G3DSA:3.30.1360.60

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC; SSF55604 PTS_EIIB

EC number: =2.7.1.69

Molecular weight: Translated: 50666; Mature: 50535

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS51098 PTS_EIIB_TYPE_1; PS01035 PTS_EIIB_TYPE_1_CYS; PS51103 PTS_EIIC_TYPE_1

Important sites: ACT_SITE 27-27

Signals:

None

Transmembrane regions:

HASH(0xb59bf88)-; HASH(0xbde22a8)-; HASH(0xb574214)-; HASH(0xbfc27cc)-; HASH(0xc886bcc)-; HASH(0xc5637dc)-; HASH(0xc82e7c4)-; HASH(0xbff0e38)-; HASH(0xbd67ae0)-; HASH(0xb0700bc)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKEQQLAERIIAAVGGMDNIDSVMNCMTRVRIKVLDENKVDDQELRHIDGVMGVIHDER
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHEECCC
IQVVVGPGTVNKVANHMAELSGVKLGDPIPHHHNDSEKMDYKSYAADKAKANKEAHKAKQ
EEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KNGKLNKVLKSIANIFIPLIPAFIGAGLIGGIAAVLSNLMVAGYISGAWITQLITVFNVI
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KDGMLAYLAIFTGINAAKEFGATPGLGGVIGGTTLLTGIAGKNILMNVFTGEPLQPGQGG
HHHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCC
IIGVIFAVWILSIVEKRLHKIVPNAIDIIVTPTIALLIVGLLTIFIFMPLAGFVSDSLVS
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVNGIISIGGVFSGFIIGASFLPLVMLGLHHIFTPIHIEMINQSGATYLLPIAAMAGAGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEHHHHHHCCCCH
VGAALALWVRCKRNTTLRNTLKGALPVGFLGIGEPLIYGVTLPLGRPFLTACIGGGIGGA
HHHHHHHHHHHCCCCHHHHHHHHCCCCCHHCCCCHHHEEEECCCCCHHHHHHHCCCHHHH
VIGGIGHIGAKAIGPSGVSLLPLISDNMYLGYIAGLLAAYAGGFVCTYLFGTTKAMRQTD
HHHHHHHHCCCCCCCCCCEEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGD
CCCH
>Mature Secondary Structure 
TKEQQLAERIIAAVGGMDNIDSVMNCMTRVRIKVLDENKVDDQELRHIDGVMGVIHDER
CCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHEECCC
IQVVVGPGTVNKVANHMAELSGVKLGDPIPHHHNDSEKMDYKSYAADKAKANKEAHKAKQ
EEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
KNGKLNKVLKSIANIFIPLIPAFIGAGLIGGIAAVLSNLMVAGYISGAWITQLITVFNVI
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KDGMLAYLAIFTGINAAKEFGATPGLGGVIGGTTLLTGIAGKNILMNVFTGEPLQPGQGG
HHHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCC
IIGVIFAVWILSIVEKRLHKIVPNAIDIIVTPTIALLIVGLLTIFIFMPLAGFVSDSLVS
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVNGIISIGGVFSGFIIGASFLPLVMLGLHHIFTPIHIEMINQSGATYLLPIAAMAGAGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEHHHHHHCCCCH
VGAALALWVRCKRNTTLRNTLKGALPVGFLGIGEPLIYGVTLPLGRPFLTACIGGGIGGA
HHHHHHHHHHHCCCCHHHHHHHHCCCCCHHCCCCHHHEEEECCCCCHHHHHHHCCCHHHH
VIGGIGHIGAKAIGPSGVSLLPLISDNMYLGYIAGLLAAYAGGFVCTYLFGTTKAMRQTD
HHHHHHHHCCCCCCCCCCEEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGD
CCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA