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The map label for this gene is nutA [H]

Identifier: 15925728

GI number: 15925728

Start: 31006

End: 33324

Strand: Direct

Name: nutA [H]

Synonym: SA0022

Alternate gene names: 15925728

Gene position: 31006-33324 (Clockwise)

Preceding gene: 15925727

Following gene: 15925729

Centisome position: 1.1

GC content: 38.38

Gene sequence:

>2319_bases
ATGAAAGCTTTATTACTTAAAACAAGTGTATGGCTCGTTTTGCTTTTTAGTGTGATGGGATTATGGCAAGTCTCGAACGC
GGCTGAGCAGTATACACCAATCAAAGCACATGTAGTAACAACGATAGACAAAGCAACAACAGATAAGCAACAAGTAACGC
CAACAAAGGAAGCGGCTCATCAATTTGGTGAAGAAGCGGCAACCAACGTATCAGCATCAGCACAGGGAACAGCTGATGAA
ATAAACAATAAAGTAACATCCAACGCATTTTCTAACAAACCATCTACAGCAGTTTCAACAAAAGTAAACGAAACGCACGA
TGTAGATACACAACAAGCCTCAACACAAAAACCAACTCAATCAGCAACATTCACATTATCAAATGCTAAAACAGCATCAC
TTTCACCACGAATGTTTGCTGCCAATGTACCACAAACAACAACACATAAAATATTACATACAAATGATATCCATGGCCGA
CTAGCCGAAGAAAAAGGGCGTGTCATCGGTATGGCTAAATTAAAAACAATAAAAGAACAAGAAAAGCCTGATTTAATGTT
AGACGCAGGAGACGCCTTCCAAGGTTTACCACTTTCAAACCAGTCTAAAGGTGAAGAAATGGCTAAAGCAATGAATGCAG
TAGGTTATGATGCTATGGCAGTGGGTAACCATGAATTTGACTTTGGATACGATCAGTTGAAAAAGTTAGAGGGTATGTTA
GACTTCCCGATGCTAAGTACTAACGTTTACAAAGATGGGAAACGCGCGTTTAAGCCTTCAACAATTGTAACGAAAAATGG
TATTCGTTATGGAATTATTGGCGTAACGACACCAGAAACAAAGACGAAAACAAGACCTGAGGGCATTAAAGGTGTTGAAT
TTAGAGATCCATTACAAAGTGTGACAGCAGAAATGATGCGTATTTATAAAGACGTAGATACATTTGTTGTTATATCACAT
TTAGGGATTGATCCTTCAACACAAGAAACATGGCGTGGTGATTACTTAGTGAAACAATTAAGTCAAAATCCACAATTGAA
GAAACGTATTACAGTCATTGATGGTCATTCACATACCGTACTTCAAAATGGTCAAATTTATAACAATGATGCATTAGCAC
AAACAGGTACAGCACTTGCGAATATCGGTAAGGTTACATTTAATTACCGCAATGGAGAGGTATCAAATATTAAACCGTCA
TTGATTAATGTTAAAGACGTTGAAAATGTAACACCGAACAAAGCATTAGCTGAACAAATTAATCAAGCTGATCAAACATT
TAGAGCACAAACAGCAGAGGTTATTATTCCAAATAATACCATTGATTTCAAAGGAGAAAGAGATGACGTTAGAACGCGTG
AAACAAATTTAGGAAACGCGATTGCAGATGCTATGGAAGCGTATGGCGTTAAGAATTTCTCTAAAAAGACTGACTTTGCC
GTGACAAATGGTGGAGGTATTCGTGCCTCTATCGCAAAAGGTAAGGTGACACGCTATGATTTAATCTCAGTATTACCATT
TGGAAATACGATTGCGCAAATTGATGTAAAAGGTTCAGACGTCTGGACAGCTTTCGAACATAGTTTAGGTGCACCAACAA
CACAAAAAGACGGTAAGACAGTATTAACAGCGAATGGCGGTTTACTACATATCTCTGATTCAATTCGTGTTTACTATGAT
ATGAATAAACCGTCTGGCAAACGAATTAACGCTATTCAAATTTTAAATAAAGAGACAGGTAAGTTTGAAAATATTGATTT
AAAACGTGTATATCATGTAACGATGAATGACTTCACAGCATCAGGTGGCGACGGATATAGTATGTTCGGTGGCCCTAGAG
AAGAAGGTATTTCATTAGATCAAGTACTAGCAAGTTATTTAAAAACAGCTAACATAGCTAAGTATGATACGACAGAACCA
CAACGTATGTTATTAGGTAAACCAGCAGTAAGTGAACAACCAGCTAAAGGACAACAAGGTAGCAAAGGTAGTGAGTCTGG
TAAAGATGTACAACCAATTGGTGACGACAAAGCGATGAATCCAGCGAAACAACCAGCGACAGGTAAAGTTGTATTGTTAC
CAACGCATAGAGGAACTGTTAGTAGCGGTACAGAAGGTTCTGGTCGCACATTAGAAGGAGCTACTGTATCAAGCAAGAGT
GGGAACCAATTGGTTAGAATGTCAGTGCCTAAAGGTAGCGCGCATGAGAAACAGTTACCAAAAACTGGAACTAATCAAAG
CTCAAGCCCAGCAGCGATGTTTGTATTAGTAGCAGGTATAGGTTTAATCGCGACTGTACGACGTAGAAAAGCTAGTTAA

Upstream 100 bases:

>100_bases
ATATTAAATGTAATTTATAAATAATTTACATAAAATCAATCATTTTAATATAAGGATTATGATAATATATTGGTGTATGA
CAGTTAATGGAGGGAACGAA

Downstream 100 bases:

>100_bases
AATATATTGAAAACAATACTACTGTATTTCTTAAATAAGAGGTACGGTAGTGTTTTTTTATGGAAAAAAGCTATAAACGT
TGATAAACATGGGATATAAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 772; Mature: 772

Protein sequence:

>772_residues
MKALLLKTSVWLVLLFSVMGLWQVSNAAEQYTPIKAHVVTTIDKATTDKQQVTPTKEAAHQFGEEAATNVSASAQGTADE
INNKVTSNAFSNKPSTAVSTKVNETHDVDTQQASTQKPTQSATFTLSNAKTASLSPRMFAANVPQTTTHKILHTNDIHGR
LAEEKGRVIGMAKLKTIKEQEKPDLMLDAGDAFQGLPLSNQSKGEEMAKAMNAVGYDAMAVGNHEFDFGYDQLKKLEGML
DFPMLSTNVYKDGKRAFKPSTIVTKNGIRYGIIGVTTPETKTKTRPEGIKGVEFRDPLQSVTAEMMRIYKDVDTFVVISH
LGIDPSTQETWRGDYLVKQLSQNPQLKKRITVIDGHSHTVLQNGQIYNNDALAQTGTALANIGKVTFNYRNGEVSNIKPS
LINVKDVENVTPNKALAEQINQADQTFRAQTAEVIIPNNTIDFKGERDDVRTRETNLGNAIADAMEAYGVKNFSKKTDFA
VTNGGGIRASIAKGKVTRYDLISVLPFGNTIAQIDVKGSDVWTAFEHSLGAPTTQKDGKTVLTANGGLLHISDSIRVYYD
MNKPSGKRINAIQILNKETGKFENIDLKRVYHVTMNDFTASGGDGYSMFGGPREEGISLDQVLASYLKTANIAKYDTTEP
QRMLLGKPAVSEQPAKGQQGSKGSESGKDVQPIGDDKAMNPAKQPATGKVVLLPTHRGTVSSGTEGSGRTLEGATVSSKS
GNQLVRMSVPKGSAHEKQLPKTGTNQSSSPAAMFVLVAGIGLIATVRRRKAS

Sequences:

>Translated_772_residues
MKALLLKTSVWLVLLFSVMGLWQVSNAAEQYTPIKAHVVTTIDKATTDKQQVTPTKEAAHQFGEEAATNVSASAQGTADE
INNKVTSNAFSNKPSTAVSTKVNETHDVDTQQASTQKPTQSATFTLSNAKTASLSPRMFAANVPQTTTHKILHTNDIHGR
LAEEKGRVIGMAKLKTIKEQEKPDLMLDAGDAFQGLPLSNQSKGEEMAKAMNAVGYDAMAVGNHEFDFGYDQLKKLEGML
DFPMLSTNVYKDGKRAFKPSTIVTKNGIRYGIIGVTTPETKTKTRPEGIKGVEFRDPLQSVTAEMMRIYKDVDTFVVISH
LGIDPSTQETWRGDYLVKQLSQNPQLKKRITVIDGHSHTVLQNGQIYNNDALAQTGTALANIGKVTFNYRNGEVSNIKPS
LINVKDVENVTPNKALAEQINQADQTFRAQTAEVIIPNNTIDFKGERDDVRTRETNLGNAIADAMEAYGVKNFSKKTDFA
VTNGGGIRASIAKGKVTRYDLISVLPFGNTIAQIDVKGSDVWTAFEHSLGAPTTQKDGKTVLTANGGLLHISDSIRVYYD
MNKPSGKRINAIQILNKETGKFENIDLKRVYHVTMNDFTASGGDGYSMFGGPREEGISLDQVLASYLKTANIAKYDTTEP
QRMLLGKPAVSEQPAKGQQGSKGSESGKDVQPIGDDKAMNPAKQPATGKVVLLPTHRGTVSSGTEGSGRTLEGATVSSKS
GNQLVRMSVPKGSAHEKQLPKTGTNQSSSPAAMFVLVAGIGLIATVRRRKAS
>Mature_772_residues
MKALLLKTSVWLVLLFSVMGLWQVSNAAEQYTPIKAHVVTTIDKATTDKQQVTPTKEAAHQFGEEAATNVSASAQGTADE
INNKVTSNAFSNKPSTAVSTKVNETHDVDTQQASTQKPTQSATFTLSNAKTASLSPRMFAANVPQTTTHKILHTNDIHGR
LAEEKGRVIGMAKLKTIKEQEKPDLMLDAGDAFQGLPLSNQSKGEEMAKAMNAVGYDAMAVGNHEFDFGYDQLKKLEGML
DFPMLSTNVYKDGKRAFKPSTIVTKNGIRYGIIGVTTPETKTKTRPEGIKGVEFRDPLQSVTAEMMRIYKDVDTFVVISH
LGIDPSTQETWRGDYLVKQLSQNPQLKKRITVIDGHSHTVLQNGQIYNNDALAQTGTALANIGKVTFNYRNGEVSNIKPS
LINVKDVENVTPNKALAEQINQADQTFRAQTAEVIIPNNTIDFKGERDDVRTRETNLGNAIADAMEAYGVKNFSKKTDFA
VTNGGGIRASIAKGKVTRYDLISVLPFGNTIAQIDVKGSDVWTAFEHSLGAPTTQKDGKTVLTANGGLLHISDSIRVYYD
MNKPSGKRINAIQILNKETGKFENIDLKRVYHVTMNDFTASGGDGYSMFGGPREEGISLDQVLASYLKTANIAKYDTTEP
QRMLLGKPAVSEQPAKGQQGSKGSESGKDVQPIGDDKAMNPAKQPATGKVVLLPTHRGTVSSGTEGSGRTLEGATVSSKS
GNQLVRMSVPKGSAHEKQLPKTGTNQSSSPAAMFVLVAGIGLIATVRRRKAS

Specific function: Degradation of extracellular 5'-nucleotides for nutritional needs [H]

COG id: COG0737

COG function: function code F; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5'-nucleotidase family [H]

Homologues:

Organism=Homo sapiens, GI4505467, Length=512, Percent_Identity=28.7109375, Blast_Score=156, Evalue=6e-38,
Organism=Escherichia coli, GI1786687, Length=551, Percent_Identity=27.7676950998185, Blast_Score=162, Evalue=8e-41,
Organism=Escherichia coli, GI1790658, Length=264, Percent_Identity=26.8939393939394, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19922446, Length=492, Percent_Identity=27.0325203252033, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24654424, Length=492, Percent_Identity=27.0325203252033, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28573524, Length=527, Percent_Identity=25.0474383301708, Blast_Score=137, Evalue=4e-32,
Organism=Drosophila melanogaster, GI19922444, Length=583, Percent_Identity=26.0720411663808, Blast_Score=134, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24641187, Length=534, Percent_Identity=26.9662921348315, Blast_Score=126, Evalue=5e-29,
Organism=Drosophila melanogaster, GI19921980, Length=478, Percent_Identity=26.3598326359833, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI161076508, Length=478, Percent_Identity=26.3598326359833, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24652512, Length=478, Percent_Identity=26.3598326359833, Blast_Score=110, Evalue=3e-24,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008334
- InterPro:   IPR006146
- InterPro:   IPR006179
- InterPro:   IPR004843 [H]

Pfam domain/function: PF02872 5_nucleotid_C; PF00149 Metallophos [H]

EC number: =3.1.3.5 [H]

Molecular weight: Translated: 83499; Mature: 83499

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS50847 GRAM_POS_ANCHORING ; PS00786 5_NUCLEOTIDASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALLLKTSVWLVLLFSVMGLWQVSNAAEQYTPIKAHVVTTIDKATTDKQQVTPTKEAAH
CCEEEEHHHHHHHHHHHHHHHHHHHCHHHHCCCCEEEEEEEEHHCCCCCHHCCCHHHHHH
QFGEEAATNVSASAQGTADEINNKVTSNAFSNKPSTAVSTKVNETHDVDTQQASTQKPTQ
HHHHHHHCCCCCCCCCCHHHHHCHHHHCCCCCCCCCEEEECCCCCCCCCCHHHCCCCCCC
SATFTLSNAKTASLSPRMFAANVPQTTTHKILHTNDIHGRLAEEKGRVIGMAKLKTIKEQ
CEEEEECCCCCCCCCCCEEECCCCCCCCEEEEECCCCCCHHHHHCCCEEEHHHHHHHHHC
EKPDLMLDAGDAFQGLPLSNQSKGEEMAKAMNAVGYDAMAVGNHEFDFGYDQLKKLEGML
CCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHCCC
DFPMLSTNVYKDGKRAFKPSTIVTKNGIRYGIIGVTTPETKTKTRPEGIKGVEFRDPLQS
CCCCCCCHHCCCCHHHCCCCEEEEECCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHH
VTAEMMRIYKDVDTFVVISHLGIDPSTQETWRGDYLVKQLSQNPQLKKRITVIDGHSHTV
HHHHHHHHHHHHHHEEEEEECCCCCCCCHHHCHHHHHHHHHCCCCCEEEEEEEECCCEEE
LQNGQIYNNDALAQTGTALANIGKVTFNYRNGEVSNIKPSLINVKDVENVTPNKALAEQI
EECCEEECCCCHHHCCHHHHHCCEEEEEECCCCCCCCCCCEEEEHHCCCCCCCHHHHHHH
NQADQTFRAQTAEVIIPNNTIDFKGERDDVRTRETNLGNAIADAMEAYGVKNFSKKTDFA
HHHHHHHHHCCEEEEECCCEEECCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCCEE
VTNGGGIRASIAKGKVTRYDLISVLPFGNTIAQIDVKGSDVWTAFEHSLGAPTTQKDGKT
EECCCCEEEECCCCCCCCEEEEEEECCCCEEEEEEECCCCCHHHHHHHCCCCCCCCCCCE
VLTANGGLLHISDSIRVYYDMNKPSGKRINAIQILNKETGKFENIDLKRVYHVTMNDFTA
EEEECCCEEEEECCEEEEEECCCCCCCEEEEEEEECCCCCCCCCCCEEEEEEEEECCEEC
SGGDGYSMFGGPREEGISLDQVLASYLKTANIAKYDTTEPQRMLLGKPAVSEQPAKGQQG
CCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCC
SKGSESGKDVQPIGDDKAMNPAKQPATGKVVLLPTHRGTVSSGTEGSGRTLEGATVSSKS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEECCCEECCCC
GNQLVRMSVPKGSAHEKQLPKTGTNQSSSPAAMFVLVAGIGLIATVRRRKAS
CCEEEEEECCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKALLLKTSVWLVLLFSVMGLWQVSNAAEQYTPIKAHVVTTIDKATTDKQQVTPTKEAAH
CCEEEEHHHHHHHHHHHHHHHHHHHCHHHHCCCCEEEEEEEEHHCCCCCHHCCCHHHHHH
QFGEEAATNVSASAQGTADEINNKVTSNAFSNKPSTAVSTKVNETHDVDTQQASTQKPTQ
HHHHHHHCCCCCCCCCCHHHHHCHHHHCCCCCCCCCEEEECCCCCCCCCCHHHCCCCCCC
SATFTLSNAKTASLSPRMFAANVPQTTTHKILHTNDIHGRLAEEKGRVIGMAKLKTIKEQ
CEEEEECCCCCCCCCCCEEECCCCCCCCEEEEECCCCCCHHHHHCCCEEEHHHHHHHHHC
EKPDLMLDAGDAFQGLPLSNQSKGEEMAKAMNAVGYDAMAVGNHEFDFGYDQLKKLEGML
CCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHCCC
DFPMLSTNVYKDGKRAFKPSTIVTKNGIRYGIIGVTTPETKTKTRPEGIKGVEFRDPLQS
CCCCCCCHHCCCCHHHCCCCEEEEECCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHH
VTAEMMRIYKDVDTFVVISHLGIDPSTQETWRGDYLVKQLSQNPQLKKRITVIDGHSHTV
HHHHHHHHHHHHHHEEEEEECCCCCCCCHHHCHHHHHHHHHCCCCCEEEEEEEECCCEEE
LQNGQIYNNDALAQTGTALANIGKVTFNYRNGEVSNIKPSLINVKDVENVTPNKALAEQI
EECCEEECCCCHHHCCHHHHHCCEEEEEECCCCCCCCCCCEEEEHHCCCCCCCHHHHHHH
NQADQTFRAQTAEVIIPNNTIDFKGERDDVRTRETNLGNAIADAMEAYGVKNFSKKTDFA
HHHHHHHHHCCEEEEECCCEEECCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCCCCCEE
VTNGGGIRASIAKGKVTRYDLISVLPFGNTIAQIDVKGSDVWTAFEHSLGAPTTQKDGKT
EECCCCEEEECCCCCCCCEEEEEEECCCCEEEEEEECCCCCHHHHHHHCCCCCCCCCCCE
VLTANGGLLHISDSIRVYYDMNKPSGKRINAIQILNKETGKFENIDLKRVYHVTMNDFTA
EEEECCCEEEEECCEEEEEECCCCCCCEEEEEEEECCCCCCCCCCCEEEEEEEEECCEEC
SGGDGYSMFGGPREEGISLDQVLASYLKTANIAKYDTTEPQRMLLGKPAVSEQPAKGQQG
CCCCCCCCCCCCHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCC
SKGSESGKDVQPIGDDKAMNPAKQPATGKVVLLPTHRGTVSSGTEGSGRTLEGATVSSKS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCEECCCEECCCC
GNQLVRMSVPKGSAHEKQLPKTGTNQSSSPAAMFVLVAGIGLIATVRRRKAS
CCEEEEEECCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2016269; 12620739 [H]