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The map label for this gene is gldA [H]

Identifier: 15675817

GI number: 15675817

Start: 1703651

End: 1704739

Strand: Reverse

Name: gldA [H]

Synonym: SPy_2047

Alternate gene names: 15675817

Gene position: 1704739-1703651 (Counterclockwise)

Preceding gene: 15675818

Following gene: 15675815

Centisome position: 92.03

GC content: 45.27

Gene sequence:

>1089_bases
ATGAAAGTATTTGCAAGTCCATCTCGTTACATTCAAGGTAAAAATGCCTTGTTTACCAATGTTAAAACCCTAAAACAACT
AGGGGATAGCCCCATTTTACTGTGTGATGACGTGGTGTATGGCATCGTCGGAGAAAGATTTGAAAGCTATTTGATAGATA
ATGGCATGACTCCTGTTCACGTAGCCTTTAATGGCGAAGCCTCAGATAATGAAATCAGCCGCGTGGTTGCCATTGCCAAG
GAAAATGGCAATGATGTTATTATTGGACTTGGTGGTGGAAAAACCATTGACAGTGCTAAGGCTATCGCTGACTTACTTGC
TGTTCCGGTGATTATTGCCCCAACCATTGCTTCAACAGATGCCCCAACCTCAGCCTTATCGGTTATTTACACCGATGAAG
GAGCCTTTGAAAAATACATTTTCTATTCAAAGAATCCAGATCTTGTATTGGTTGACACACAAGTGATCTGTCAGGCACCA
AAACGCTTATTGGCGTCAGGGATTGCAGATGGGTTAGCAACATGGGTAGAGGCGCGTGCTGTTATGCAAAAAAATGGAGA
CACCATGGCAGGTGGCAATCAAACCTTGGCAGGAGTTGCCATTGCCAAAGCCTGTGAGCAGACCTTGTTTGCAGATGGCC
TAAAAGCGATGGCTAGCTGTGACAGACAAGTCGTGACCCCGGCCTTGGAAAATGTCATTGAAGCCAATACACTTCTTAGT
GGGCTTGGTTTTGAAAGTGCGGGTCTGGCTGCTGCACATGCCATTCACAATGGCTTTACAGCGCTGACAGGTGCTATTCA
TCACCTTACCCATGGTGAAAAAGTCGCCTATGGCACGTTGACCCAACTCTTCTTGGAAAATCGTTCGCGTGAAGAAATTG
ACCGCTACATCGACTTTTACCAAGCTATTGGCATGCCAACAACCCTCAAAGAAATGCATTTAGACACGGCTACTCAAGAG
GATTTCTTAAAAATTGGCCGTCAAGCAACCATGGCAGGCGAAACCATCCATCAAATGCCATTTGTTATCAGTCCAGAAGA
TGTAGCAGCGGCTTTGGTTGCTGTTGATGCCTATGTTACGAGTCGATAG

Upstream 100 bases:

>100_bases
TTGGCAAGGATTGGGAAGCCATTCATCACCGCAAGAGCATTTAAGAAATAGCATCAGTAGTAATCACATCATTAGGAATC
ACAGATAAAGGAGTTCAACG

Downstream 100 bases:

>100_bases
GCTAACCAAAAAGAGATTTCTTATTTGCCAGATAACCTCAAAAAAACAAGTCTAGGGAGTCACTTCCTAGACTTGTTTTG
CTTATTGTTGGTTGGTAATA

Product: glycerol dehydrogenase

Products: NA

Alternate protein names: GDH; GLDH; GlyDH [H]

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MKVFASPSRYIQGKNALFTNVKTLKQLGDSPILLCDDVVYGIVGERFESYLIDNGMTPVHVAFNGEASDNEISRVVAIAK
ENGNDVIIGLGGGKTIDSAKAIADLLAVPVIIAPTIASTDAPTSALSVIYTDEGAFEKYIFYSKNPDLVLVDTQVICQAP
KRLLASGIADGLATWVEARAVMQKNGDTMAGGNQTLAGVAIAKACEQTLFADGLKAMASCDRQVVTPALENVIEANTLLS
GLGFESAGLAAAHAIHNGFTALTGAIHHLTHGEKVAYGTLTQLFLENRSREEIDRYIDFYQAIGMPTTLKEMHLDTATQE
DFLKIGRQATMAGETIHQMPFVISPEDVAAALVAVDAYVTSR

Sequences:

>Translated_362_residues
MKVFASPSRYIQGKNALFTNVKTLKQLGDSPILLCDDVVYGIVGERFESYLIDNGMTPVHVAFNGEASDNEISRVVAIAK
ENGNDVIIGLGGGKTIDSAKAIADLLAVPVIIAPTIASTDAPTSALSVIYTDEGAFEKYIFYSKNPDLVLVDTQVICQAP
KRLLASGIADGLATWVEARAVMQKNGDTMAGGNQTLAGVAIAKACEQTLFADGLKAMASCDRQVVTPALENVIEANTLLS
GLGFESAGLAAAHAIHNGFTALTGAIHHLTHGEKVAYGTLTQLFLENRSREEIDRYIDFYQAIGMPTTLKEMHLDTATQE
DFLKIGRQATMAGETIHQMPFVISPEDVAAALVAVDAYVTSR
>Mature_362_residues
MKVFASPSRYIQGKNALFTNVKTLKQLGDSPILLCDDVVYGIVGERFESYLIDNGMTPVHVAFNGEASDNEISRVVAIAK
ENGNDVIIGLGGGKTIDSAKAIADLLAVPVIIAPTIASTDAPTSALSVIYTDEGAFEKYIFYSKNPDLVLVDTQVICQAP
KRLLASGIADGLATWVEARAVMQKNGDTMAGGNQTLAGVAIAKACEQTLFADGLKAMASCDRQVVTPALENVIEANTLLS
GLGFESAGLAAAHAIHNGFTALTGAIHHLTHGEKVAYGTLTQLFLENRSREEIDRYIDFYQAIGMPTTLKEMHLDTATQE
DFLKIGRQATMAGETIHQMPFVISPEDVAAALVAVDAYVTSR

Specific function: Catalyzes the NAD-dependent oxidation of glycerol to dihydroxyacetone (glycerone). Allows microorganisms to utilize glycerol as a source of carbon under anaerobic conditions. Is also able to use various diols as substrates, such as propan-1,2-diol, butan-

COG id: COG0371

COG function: function code C; Glycerol dehydrogenase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI87082352, Length=357, Percent_Identity=49.2997198879552, Blast_Score=337, Evalue=9e-94,
Organism=Escherichia coli, GI1786815, Length=305, Percent_Identity=33.4426229508197, Blast_Score=144, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211
- InterPro:   IPR016205 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.6 [H]

Molecular weight: Translated: 38567; Mature: 38567

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVFASPSRYIQGKNALFTNVKTLKQLGDSPILLCDDVVYGIVGERFESYLIDNGMTPVH
CCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCEEE
VAFNGEASDNEISRVVAIAKENGNDVIIGLGGGKTIDSAKAIADLLAVPVIIAPTIASTD
EEECCCCCCCHHHEEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
APTSALSVIYTDEGAFEKYIFYSKNPDLVLVDTQVICQAPKRLLASGIADGLATWVEARA
CCCCEEEEEEECCCCCEEEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMQKNGDTMAGGNQTLAGVAIAKACEQTLFADGLKAMASCDRQVVTPALENVIEANTLLS
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
GLGFESAGLAAAHAIHNGFTALTGAIHHLTHGEKVAYGTLTQLFLENRSREEIDRYIDFY
HCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHH
QAIGMPTTLKEMHLDTATQEDFLKIGRQATMAGETIHQMPFVISPEDVAAALVAVDAYVT
HHHCCCHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHC
SR
CC
>Mature Secondary Structure
MKVFASPSRYIQGKNALFTNVKTLKQLGDSPILLCDDVVYGIVGERFESYLIDNGMTPVH
CCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCEEE
VAFNGEASDNEISRVVAIAKENGNDVIIGLGGGKTIDSAKAIADLLAVPVIIAPTIASTD
EEECCCCCCCHHHEEEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
APTSALSVIYTDEGAFEKYIFYSKNPDLVLVDTQVICQAPKRLLASGIADGLATWVEARA
CCCCEEEEEEECCCCCEEEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMQKNGDTMAGGNQTLAGVAIAKACEQTLFADGLKAMASCDRQVVTPALENVIEANTLLS
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
GLGFESAGLAAAHAIHNGFTALTGAIHHLTHGEKVAYGTLTQLFLENRSREEIDRYIDFY
HCCCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHH
QAIGMPTTLKEMHLDTATQEDFLKIGRQATMAGETIHQMPFVISPEDVAAALVAVDAYVT
HHHCCCHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHC
SR
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1339360 [H]