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The map label for this gene is trpG [H]

Identifier: 15675781

GI number: 15675781

Start: 1661572

End: 1662138

Strand: Direct

Name: trpG [H]

Synonym: SPy_1991

Alternate gene names: 15675781

Gene position: 1661572-1662138 (Clockwise)

Preceding gene: 15675780

Following gene: 15675782

Centisome position: 89.7

GC content: 45.5

Gene sequence:

>567_bases
ATGATACTCTTAATTGATAATTACGATTCATTTACCTACAACCTCGCCCAATATTTAAGTGAATTTGACGAGACGATTGT
CTTGTATAACCAAGACCCAAACTTATATGACATGGCCAAAAAAGCTAACGCTCTAGTCCTCTCACCTGGTCCTGGTTGGC
CCAAGGAAGCCAACCAAATGCCAAAACTCATTCAAGACTTTTACCAAACAAAACCTATCTTAGGAGTGTGTCTGGGACAC
CAAGCTATCGCTGAAACTTTAGGGGGAACCTTACGCTTGGCCAAACGCGTCATGCATGGGAGACAAAGCACCATTGAAAC
GCAAGGCCCTGCTAGTCTTTTTCGCTCCCTGCCACAAGAGATCACCGTCATGCGCTACCATTCCATCGTTGTGGATCAGT
TACCAAAAGGTTTTAGCGTAACCGCTAGAGACTGTGACGATCAAGAAATCATGGCATTTGAACACCACACCCTGCCACTT
TTTGGGCTACAATTTCACCCAGAAAGCATCGGAACTCCTGATGGCATGACCATGATTGCCAACTTCATCGCAGCCATTCC
CCGTTAA

Upstream 100 bases:

>100_bases
GTGGCCTTTATCCTCTCAACCTTGAGCTTACTCACCTTGATGCCCTCTTAGCTAAGAGTCAAGCCTAAACTGCCACTCAT
CTTTTGTTATTAAGGAACCT

Downstream 100 bases:

>100_bases
TCTCATCCCCCAAAAGAAAGGAGGACAGTTACATGCCTGATCATTTAGCGCTCAGAATGCGCCCCAAAACCATTTCAGAG
GTCATCGGACAAAAACACCT

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MILLIDNYDSFTYNLAQYLSEFDETIVLYNQDPNLYDMAKKANALVLSPGPGWPKEANQMPKLIQDFYQTKPILGVCLGH
QAIAETLGGTLRLAKRVMHGRQSTIETQGPASLFRSLPQEITVMRYHSIVVDQLPKGFSVTARDCDDQEIMAFEHHTLPL
FGLQFHPESIGTPDGMTMIANFIAAIPR

Sequences:

>Translated_188_residues
MILLIDNYDSFTYNLAQYLSEFDETIVLYNQDPNLYDMAKKANALVLSPGPGWPKEANQMPKLIQDFYQTKPILGVCLGH
QAIAETLGGTLRLAKRVMHGRQSTIETQGPASLFRSLPQEITVMRYHSIVVDQLPKGFSVTARDCDDQEIMAFEHHTLPL
FGLQFHPESIGTPDGMTMIANFIAAIPR
>Mature_188_residues
MILLIDNYDSFTYNLAQYLSEFDETIVLYNQDPNLYDMAKKANALVLSPGPGWPKEANQMPKLIQDFYQTKPILGVCLGH
QAIAETLGGTLRLAKRVMHGRQSTIETQGPASLFRSLPQEITVMRYHSIVVDQLPKGFSVTARDCDDQEIMAFEHHTLPL
FGLQFHPESIGTPDGMTMIANFIAAIPR

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI4504035, Length=145, Percent_Identity=32.4137931034483, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1789760, Length=187, Percent_Identity=47.0588235294118, Blast_Score=153, Evalue=6e-39,
Organism=Escherichia coli, GI1787517, Length=188, Percent_Identity=42.0212765957447, Blast_Score=135, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6322638, Length=189, Percent_Identity=35.978835978836, Blast_Score=120, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6323873, Length=182, Percent_Identity=25.2747252747253, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324361, Length=210, Percent_Identity=27.1428571428571, Blast_Score=63, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281365319, Length=144, Percent_Identity=29.8611111111111, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 21085; Mature: 21085

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLIDNYDSFTYNLAQYLSEFDETIVLYNQDPNLYDMAKKANALVLSPGPGWPKEANQM
CEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHCCEEEECCCCCCCHHHHHH
PKLIQDFYQTKPILGVCLGHQAIAETLGGTLRLAKRVMHGRQSTIETQGPASLFRSLPQE
HHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHH
ITVMRYHSIVVDQLPKGFSVTARDCDDQEIMAFEHHTLPLFGLQFHPESIGTPDGMTMIA
HHHHHHHHHHHHHCCCCCEEEECCCCCCHHEEECCCCCEEEEEEECCCCCCCCCHHHHHH
NFIAAIPR
HHHHHCCC
>Mature Secondary Structure
MILLIDNYDSFTYNLAQYLSEFDETIVLYNQDPNLYDMAKKANALVLSPGPGWPKEANQM
CEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHCCEEEECCCCCCCHHHHHH
PKLIQDFYQTKPILGVCLGHQAIAETLGGTLRLAKRVMHGRQSTIETQGPASLFRSLPQE
HHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHCCCCCCHHHHHHHHHHH
ITVMRYHSIVVDQLPKGFSVTARDCDDQEIMAFEHHTLPLFGLQFHPESIGTPDGMTMIA
HHHHHHHHHHHHHCCCCCEEEECCCCCCHHEEECCCCCEEEEEEECCCCCCCCCHHHHHH
NFIAAIPR
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1400208; 11337471 [H]