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The map label for this gene is pabB [H]

Identifier: 15675780

GI number: 15675780

Start: 1659782

End: 1661539

Strand: Direct

Name: pabB [H]

Synonym: SPy_1990

Alternate gene names: 15675780

Gene position: 1659782-1661539 (Clockwise)

Preceding gene: 15675774

Following gene: 15675781

Centisome position: 89.6

GC content: 43.86

Gene sequence:

>1758_bases
ATGCATAGAAAAACTATTATTGATTTCAAAGAGCTCGGGCAACGCTATCTTTTTGATGAGCCATTAGTAGAATTGGTAGC
CAAGTCCTTAGATCAGGTCGGTCCAGTCATTGAAAAAGTACAACACTACCAACAGCTGGGCTATTACGTGGTGGGCTATC
TCAGTTATGAAGCAGCTGCTTTTTTTGACAATGCCCTACAAACCCATAATGACAGACTAGGCAACGAGTACCTTGCCTAT
TTTACAGTGCACAAAACCTGTCAAAAAAAAGACCTACCTCTTGATTATGACAGCATTACTATCCCTAACCAATGGGTCAG
CGCAACTCAAAAAGAAGCCTATCAAAAAGCCATTGAAACCATTCACCGTGAGATGCAACAGGGCAATACTTATCAGGTTA
ACTACACCCTTCAATTAACTCAGGAACTCAATGCAGCTGATAGTTTAGCCATTTACAATAAACTCGTCGTTGAACAGGCT
GCTGGCTACAATGCCTACATCGCCCATGATGAGTTTGCCGTTATTTCAGCTAGTCCTGAATTGTTCTTTAAACAAGAGGG
CAACAGGTTAACTACTAGGCCTATGAAAGGCACCACCAAACGAGGGGTTAATAGCTGGCTGGATCAACAAGAACATGACT
GGCTCCAAGCTGACGGGAAAAACCGTTCTGAAAACATGATGATTGTGGATTTGCTCCGCAATGACATGGGGAAAATTTGC
CAAACAGGCAGTGTTCGTGTTGATAGGCTCTGTGAGGTCGAGCGATACTCTACCGTCTGGCAAATGACCTCAACTATTGT
TGGTGACCTCAAAGCGGACTGTGACCTGATAGACATTCTCAAAGCTCTCTTTCCTTGTGGCTCTATCACAGGGGCACCAA
AAGTCTCCACCATGGCAATTATCACATCTCTGGAGCCAAAACCAAGGGGGATTTATTGTGGAAGTATTGGCATTTGCCTA
CCTGATGGTCGCCGTTTCTTCAATGTTCCCATTAGAACCATCCAGCTCAGTCATAATCAAGCTACTTATGGTGTCGGAGG
CGGCATCACTTGGCAAAGCAAGTGGGAAGACGAATACGAGGAAGTCCATCAAAAAACAGCTTTTCTCTATCGGCACAAAC
AAATCTTTGACCTCAAAACAACCGCCAAGGTGGAACACAAAAAAATAGCCTTCCTTGAGCAACACCTCAATCGCCTTAAA
GAAGCAGCCACTTATTTTGCTTACCCTTATAATGAAAAAGCTTTGCAGAAACAACTGTCAACCTATTTGGAAAATAAGAA
TAATGCTGCCTACCGTTTGATGATTCGTTTATCCAAAGATGGAAAGATTAGCCTCTCTGATCAACCCTTGGAACCTTTGT
CAGCCGATTTTCTGACAGCTCAACTCTCTTTACAGAAAAAGGACGTGACAGCTTCGCCTTTTACCTACTTTAAGACCAGC
TACCGGCCTCATATTGAGCAAAAATCTTATGAACAGCTATTCTATAACCAAGCGGGGCAATTATTGGAAACGTCCATTGG
CAATCTCTTTGTTCAGCTGGGTCAGACCCTCTACACACCACCAGTGGCTGTGGGGATTTTACCAGGACTTTTTCGCCAAG
AACTGCTAGCTACTGGTCAAGCTCAGGAAAAAGAGGTGACACTAGCTGATTTAAAAGAGGCTAGCGCTATTTTTGGAGGA
AATGCTGTCCGTGGCCTTTATCCTCTCAACCTTGAGCTTACTCACCTTGATGCCCTCTTAGCTAAGAGTCAAGCCTAA

Upstream 100 bases:

>100_bases
TATTAACTGAATTATAACATATTTGACTAATATTGACCATAAGAGAAGGTCTTAATGGCAGGATCACCTCTAGCAACCGC
TTTTATGATATAATTTGGGT

Downstream 100 bases:

>100_bases
ACTGCCACTCATCTTTTGTTATTAAGGAACCTATGATACTCTTAATTGATAATTACGATTCATTTACCTACAACCTCGCC
CAATATTTAAGTGAATTTGA

Product: putative para-aminobenzoate synthetase

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 585; Mature: 585

Protein sequence:

>585_residues
MHRKTIIDFKELGQRYLFDEPLVELVAKSLDQVGPVIEKVQHYQQLGYYVVGYLSYEAAAFFDNALQTHNDRLGNEYLAY
FTVHKTCQKKDLPLDYDSITIPNQWVSATQKEAYQKAIETIHREMQQGNTYQVNYTLQLTQELNAADSLAIYNKLVVEQA
AGYNAYIAHDEFAVISASPELFFKQEGNRLTTRPMKGTTKRGVNSWLDQQEHDWLQADGKNRSENMMIVDLLRNDMGKIC
QTGSVRVDRLCEVERYSTVWQMTSTIVGDLKADCDLIDILKALFPCGSITGAPKVSTMAIITSLEPKPRGIYCGSIGICL
PDGRRFFNVPIRTIQLSHNQATYGVGGGITWQSKWEDEYEEVHQKTAFLYRHKQIFDLKTTAKVEHKKIAFLEQHLNRLK
EAATYFAYPYNEKALQKQLSTYLENKNNAAYRLMIRLSKDGKISLSDQPLEPLSADFLTAQLSLQKKDVTASPFTYFKTS
YRPHIEQKSYEQLFYNQAGQLLETSIGNLFVQLGQTLYTPPVAVGILPGLFRQELLATGQAQEKEVTLADLKEASAIFGG
NAVRGLYPLNLELTHLDALLAKSQA

Sequences:

>Translated_585_residues
MHRKTIIDFKELGQRYLFDEPLVELVAKSLDQVGPVIEKVQHYQQLGYYVVGYLSYEAAAFFDNALQTHNDRLGNEYLAY
FTVHKTCQKKDLPLDYDSITIPNQWVSATQKEAYQKAIETIHREMQQGNTYQVNYTLQLTQELNAADSLAIYNKLVVEQA
AGYNAYIAHDEFAVISASPELFFKQEGNRLTTRPMKGTTKRGVNSWLDQQEHDWLQADGKNRSENMMIVDLLRNDMGKIC
QTGSVRVDRLCEVERYSTVWQMTSTIVGDLKADCDLIDILKALFPCGSITGAPKVSTMAIITSLEPKPRGIYCGSIGICL
PDGRRFFNVPIRTIQLSHNQATYGVGGGITWQSKWEDEYEEVHQKTAFLYRHKQIFDLKTTAKVEHKKIAFLEQHLNRLK
EAATYFAYPYNEKALQKQLSTYLENKNNAAYRLMIRLSKDGKISLSDQPLEPLSADFLTAQLSLQKKDVTASPFTYFKTS
YRPHIEQKSYEQLFYNQAGQLLETSIGNLFVQLGQTLYTPPVAVGILPGLFRQELLATGQAQEKEVTLADLKEASAIFGG
NAVRGLYPLNLELTHLDALLAKSQA
>Mature_585_residues
MHRKTIIDFKELGQRYLFDEPLVELVAKSLDQVGPVIEKVQHYQQLGYYVVGYLSYEAAAFFDNALQTHNDRLGNEYLAY
FTVHKTCQKKDLPLDYDSITIPNQWVSATQKEAYQKAIETIHREMQQGNTYQVNYTLQLTQELNAADSLAIYNKLVVEQA
AGYNAYIAHDEFAVISASPELFFKQEGNRLTTRPMKGTTKRGVNSWLDQQEHDWLQADGKNRSENMMIVDLLRNDMGKIC
QTGSVRVDRLCEVERYSTVWQMTSTIVGDLKADCDLIDILKALFPCGSITGAPKVSTMAIITSLEPKPRGIYCGSIGICL
PDGRRFFNVPIRTIQLSHNQATYGVGGGITWQSKWEDEYEEVHQKTAFLYRHKQIFDLKTTAKVEHKKIAFLEQHLNRLK
EAATYFAYPYNEKALQKQLSTYLENKNNAAYRLMIRLSKDGKISLSDQPLEPLSADFLTAQLSLQKKDVTASPFTYFKTS
YRPHIEQKSYEQLFYNQAGQLLETSIGNLFVQLGQTLYTPPVAVGILPGLFRQELLATGQAQEKEVTLADLKEASAIFGG
NAVRGLYPLNLELTHLDALLAKSQA

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=305, Percent_Identity=34.7540983606557, Blast_Score=168, Evalue=1e-42,
Organism=Escherichia coli, GI1787518, Length=282, Percent_Identity=28.3687943262411, Blast_Score=126, Evalue=4e-30,
Organism=Escherichia coli, GI1786809, Length=222, Percent_Identity=24.3243243243243, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI87082077, Length=209, Percent_Identity=31.1004784688995, Blast_Score=78, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320935, Length=261, Percent_Identity=33.7164750957854, Blast_Score=155, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6324361, Length=317, Percent_Identity=29.9684542586751, Blast_Score=100, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 66361; Mature: 66361

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRKTIIDFKELGQRYLFDEPLVELVAKSLDQVGPVIEKVQHYQQLGYYVVGYLSYEAAA
CCCCEECCHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEHHHHHHH
FFDNALQTHNDRLGNEYLAYFTVHKTCQKKDLPLDYDSITIPNQWVSATQKEAYQKAIET
HHHHHHHHHCHHCCCCEEEEEEEHHHHCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHH
IHREMQQGNTYQVNYTLQLTQELNAADSLAIYNKLVVEQAAGYNAYIAHDEFAVISASPE
HHHHHHCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCC
LFFKQEGNRLTTRPMKGTTKRGVNSWLDQQEHDWLQADGKNRSENMMIVDLLRNDMGKIC
EEEECCCCEEECCCCCCCHHHHHHHHHCCHHCCHHHCCCCCCCCCEEEHHHHHHHHHHHH
QTGSVRVDRLCEVERYSTVWQMTSTIVGDLKADCDLIDILKALFPCGSITGAPKVSTMAI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHHEEE
ITSLEPKPRGIYCGSIGICLPDGRRFFNVPIRTIQLSHNQATYGVGGGITWQSKWEDEYE
EEECCCCCCEEEECCCEEECCCCCEEEECCEEEEEEECCCEEECCCCCCCCCCCCCHHHH
EVHQKTAFLYRHKQIFDLKTTAKVEHKKIAFLEQHLNRLKEAATYFAYPYNEKALQKQLS
HHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHH
TYLENKNNAAYRLMIRLSKDGKISLSDQPLEPLSADFLTAQLSLQKKDVTASPFTYFKTS
HHHCCCCCCEEEEEEEECCCCEEEECCCCCCCCCHHHHHHHHEEECCCCCCCCHHHHHCC
YRPHIEQKSYEQLFYNQAGQLLETSIGNLFVQLGQTLYTPPVAVGILPGLFRQELLATGQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
AQEKEVTLADLKEASAIFGGNAVRGLYPLNLELTHLDALLAKSQA
CCCCCCHHHHHHHHHHHHCCCCCCCEEECCEEHHHHHHHHHHCCC
>Mature Secondary Structure
MHRKTIIDFKELGQRYLFDEPLVELVAKSLDQVGPVIEKVQHYQQLGYYVVGYLSYEAAA
CCCCEECCHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEHHHHHHH
FFDNALQTHNDRLGNEYLAYFTVHKTCQKKDLPLDYDSITIPNQWVSATQKEAYQKAIET
HHHHHHHHHCHHCCCCEEEEEEEHHHHCCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHH
IHREMQQGNTYQVNYTLQLTQELNAADSLAIYNKLVVEQAAGYNAYIAHDEFAVISASPE
HHHHHHCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCC
LFFKQEGNRLTTRPMKGTTKRGVNSWLDQQEHDWLQADGKNRSENMMIVDLLRNDMGKIC
EEEECCCCEEECCCCCCCHHHHHHHHHCCHHCCHHHCCCCCCCCCEEEHHHHHHHHHHHH
QTGSVRVDRLCEVERYSTVWQMTSTIVGDLKADCDLIDILKALFPCGSITGAPKVSTMAI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHHEEE
ITSLEPKPRGIYCGSIGICLPDGRRFFNVPIRTIQLSHNQATYGVGGGITWQSKWEDEYE
EEECCCCCCEEEECCCEEECCCCCEEEECCEEEEEEECCCEEECCCCCCCCCCCCCHHHH
EVHQKTAFLYRHKQIFDLKTTAKVEHKKIAFLEQHLNRLKEAATYFAYPYNEKALQKQLS
HHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHH
TYLENKNNAAYRLMIRLSKDGKISLSDQPLEPLSADFLTAQLSLQKKDVTASPFTYFKTS
HHHCCCCCCEEEEEEEECCCCEEEECCCCCCCCCHHHHHHHHEEECCCCCCCCHHHHHCC
YRPHIEQKSYEQLFYNQAGQLLETSIGNLFVQLGQTLYTPPVAVGILPGLFRQELLATGQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
AQEKEVTLADLKEASAIFGGNAVRGLYPLNLELTHLDALLAKSQA
CCCCCCHHHHHHHHHHHHCCCCCCCEEECCEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]