Click here to switch to the map view.

The map label for this gene is polC

Identifier: 15675759

GI number: 15675759

Start: 1628382

End: 1632779

Strand: Reverse

Name: polC

Synonym: SPy_1961

Alternate gene names: 15675759

Gene position: 1632779-1628382 (Counterclockwise)

Preceding gene: 15675760

Following gene: 15675758

Centisome position: 88.14

GC content: 43.45

Gene sequence:

>4398_bases
ATGTCAGATTTATTCGCTAAATTGATGGACCAGATAGAAATGCCACTTGACATGAGACGTTCAAGTGCCTTTTCATCTGC
TGATATTATCGAGGTAAAGGTACATTCGGTGTCACGCTTGTGGGAATTTCATTTTGCCTTTGCAGCGGTTTTACCGATTG
CAACTTATCGTGAATTGCATGATCGTTTGATAAGAACTTTTGAGGCGGCTGACATTAAGGTAACCTTTGACATCCAAGCT
GCTCAGGTGGATTATTCAGATGATCTGCTTCAAGCTTATTACCAAGAAGCTTTTGAGCATGCACCGTGTAATAGTGCTAG
TTTTAAATCTTCTTTCTCAAAGCTCAAAGTGACTTATGAGGATGACAAACTCATTATTGCAGCGCCAGGTTTTGTGAATA
ACGATCATTTTAGAAACAATCATCTGCCTAATCTGGTCAAGCAATTAGAAGCCTTTGGCTTTGGCATCTTGACCATAGAT
ATGGTGTCAGATCAGGAAATGACTGAGCATTTGACCAAGAATTTTGTTTCCAGTCGTCAGGCTCTTGTGAAAAAGGCTGT
GCAGGATAATTTGGAAGCCCAAAAATCTCTTGAAGCCATGATGCCACCAGTTGAGGAAGCCACACCTGCTCCTAAGTTTG
ACTACAAGGAACGAGCAGCTAAGCGTCAGGCAGGGTTTGAAAAAGCAACCATCACACCAATGATTGAGATTGAGACCGAA
GAAAACCGGATTGTCTTTGAGGGTATGGTTTTTGACGTGGAGCGTAAAACGACTAGGACAGGTCGCCATATCATCAACTT
TAAAATGACAGACTATACCTCCTCGTTTGCTCTCCAAAAATGGGCTAAAGACGATGAGGAGCTCCGTAAATTTGATATGA
TTGCTAAGGGAGCTTGGTTACGGGTACAAGGGAATATTGAGACCAATCCTTTTACGAAGAGTCTCACCATGAATGTCCAG
CAGGTCAAAGAAATTGTCCGTCATGAGCGCAAAGACCTGATGCCAGAAGGGCAAAAGCGGGTCGAACTTCATGCCCACAC
CAATATGTCTACCATGGATGCCTTACCGACAGTAGAAAGCTTGATTGATACGGCAGCCAAGTGGGGACACAAGGCGATTG
CTATCACCGACCATGCTAATGTGCAAAGTTTTCCTCATGGCTACCATAGGGCTCGCAAAGCTGGGATTAAGGCTATTTTT
GGCCTAGAAGCCAATATTGTTGAGGACAAGGTGCCTATTTCTTATGAACCTGTTGATATGGATTTGCACGAAGCTACCTA
TGTGGTCTTTGACGTGGAAACCACAGGTCTATCTGCTATGAATAATGACCTGATTCAGATTGCGGCTTCCAAAATGTTTA
AAGGAAATATTGTAGAGCAGTTTGATGAATTCATTGATCCTGGGCATCCTCTTTCAGCCTTTACCACCGAATTGACAGGA
ATTACCGATAAGCATTTGCAGGGCGCCAAGCCATTGGTTACTGTCCTAAAAGCTTTTCAGGACTTTTGCAAAGATAGTAT
CTTGGTTGCCCACAACGCCAGTTTTGACGTGGGCTTTATGAACGCCAATTATGAACGCCACGACTTGCCCAAAATCACAC
AGCCTGTGATTGATACCTTAGAATTTGCTAGAAACTTGTATCCTGAGTACAAGCGTCACGGTTTGGGACCGCTCACCAAG
CGTTTCCAAGTGAGTCTAGACCACCATCATATGGCCAATTACGACGCGGAAGCCACAGGACGTCTTTTGTTTATTTTTCT
AAAAGATGCCAGAGAAAAGCATGGCATCAAAAATCTTTTGCAACTCAATACAGATTTGGTGGCTGAGGATTCTTACAAAA
AAGCGCGGATTAAGCATGCGACTATCTATGTGCAAAATCAGGTTGGTCTTAAAAATATGTTTAAGTTGGTCAGCCTTTCC
AATATCAAATATTTTGAAGGGGTGCCGCGTATTCCAAGAACCGTCTTAGATGCTCACAGAGAGGGTTTGTTACTTGGTAC
AGCTTGTTCTGACGGCGAGGTTTTTGATGCCGTTCTGACTAAAGGAATTGATGCAGCGGTTGATTTGGCTAGGTATTATG
ATTTTATCGAAATCATGCCACCAGCCATTTACCAGCCATTGGTTGTCCGTGAATTAATCAAAGATCAAGCAGGTATTGAG
CAGGTGATTCGTGACCTCATTGAAGTAGGGAAACGAGCTAAGAAACCTGTGCTTGCCACTGGGAATGTGCATTATCTAGA
GCCTGAAGAAGAGATTTACCGTGAAATTATTGTGCGTAGTCTTGGTCAGGGTGCCATGATTAATAGAACAATCGGCCGTG
GGGAAGGGGCACAGCCTGCTCCTCTACCTAAAGCGCACTTTAGAACAACCAATGAAATGCTGGATGAGTTTGCCTTTCTT
GGAAAAGACCTCGCTTATCAAGTAGTTGTGCAAAATACTCAGGATTTTGCGGACCGTATTGAGGAAGTGGAAGTGGTTAA
GGGCGATCTTTACACCCCGTATATTGATAAGGCCGAAGAGACGGTTGCCGAATTAACCTATCAAAAAGCCTTTGAAATTT
ATGGTAATCCTCTCCCAGATATTATTGATTTACGCATTGAAAAAGAGTTAACCTCTATCTTGGGGAACGGTTTTGCTGTG
ATTTATCTCGCTTCCCAAATGCTTGTTAACCGGTCAAATGAGCGAGGCTACCTAGTTGGTTCTAGGGGATCTGTAGGGTC
TAGCTTTGTCGCCACCATGATTGGGATTACTGAGGTTAATCCTATGCCGCCTCACTACGTTTGCCCGTCCTGCCAACATT
CTGAATTTATCACAGATGGGTCAGTTGGATCTGGCTATGATTTGCCTAATAAACCCTGTCCGAAATGTGGCACCCCTTAT
CAAAAAGATGGGCAAGACATTCCCTTTGAGACCTTTCTTGGGTTTGATGGGGATAAGGTGCCCGATATTGATTTGAACTT
CTCTGGTGATGACCAGCCCAGTGCCCATTTGGATGTCCGAGATATTTTTGGTGACGAATACGCCTTTCGTGCTGGAACAG
TTGGTACCGTAGCAGAAAAAACAGCTTATGGATTTGTCAAAGGCTATGAACGCGACTATGGCAAGTTCTATCGTGATGCT
GAGGTGGATCGTCTAGCAGCAGGTGCTGCTGGTGTGAAACGAACGACTGGGCAGCACCCTGGGGGGATTGTTGTTATTCC
TAATTACATGGATGTTTATGATTTTACCCCCGTGCAATATCCAGCCGATGATGTAACGGCTTCTTGGCAGACAACTCACT
TTAACTTCCATGATATTGATGAAAACGTCTTGAAACTTGATATCCTAGGGCATGATGATCCGACCATGATTCGTAAACTT
CAGGATTTATCGGGCATTGATCCTATTACTATTCCTGCTGATGATCCGGGAGTTATGGCTCTCTTTTCTGGGACAGAGGT
TTTGGGCGTTACCCCGGAACAAATTGGGACACCGACTGGTATGCTAGGCATTCCAGAATTTGGAACCAACTTTGTTCGCG
GCATGGTTAATGAGACGCATCCGACCACTTTTGCGGAGCTTTTGCAGTTGTCTGGACTATCTCATGGAACCGATGTTTGG
CTTGGTAATGCACAAGATTTGATTAAAGAAGGCATTGCAACCCTAAAAACCGTTATCGGTTGTCGTGACGACATCATGGT
TTACCTCATGCACGCAGGCTTAGAACCAAAAATGGCCTTTACCATTATGGAGCGTGTGCGTAAGGGATTATGGCTAAAAA
TTTCTGAGGAAGAACGTAATGGCTATATTGATGCCATGCGAGAAAACAATGTGCCCGACTGGTACATTGAATCGTGTGGA
AAAATCAAGTACATGTTCCCTAAAGCCCATGCGGCAGCTTATGTTTTGATGGCCCTTCGGGTGGCTTATTTCAAGGTGCA
CCACCCCATTATGTATTATTGTGCTTATTTCTCTATTCGTGCGAAGGCTTTTGAATTAAAAACCATGAGTGGTGGTTTAG
ATGCTGTTAAAGCAAGAATGGAAGATATTACTATAAAACGTAAAAATAATGAAGCCACCAATGTGGAAAATGACCTCTTT
ACAACCTTGGAGATTGTCAACGAAATGTTAGAACGCGGCTTTAAGTTTGGCAAATTAGACCTTTACAAAAGTGATGCTAT
AGAATTCCAAATCAAAGGAGATACCCTTATCCCTCCATTTATAGCGCTAGAAGGTCTGGGTGAAAACGTGGCCAAGCAAA
TCGTTAAAGCTCGTCAAGAAGGCGAATTCCTCTCTAAAATGGAATTGCGTAAACGAGGCGGGGCATCGTCAACGCTCGTT
GAGAAAATGGATGAGATGGGTATTTTAGGAAATATGCCAGAAGATAATCAATTAAGTCTTTTTGATGACTTTTTCTAG

Upstream 100 bases:

>100_bases
AAAGAACGTCAGAAGAAAGCCCTGCTTTTCTTTCCATCTAAAACTCGAAAATCATCTTGAATTGTGATAAAATAAAGCCT
AGTAAAATCAGGAGAAAATT

Downstream 100 bases:

>100_bases
ATTATCATGATGATAGTAATATGCAAAGTCATAAAAGAAGAGGGACAAGATCACTTTCTAATCTCTCTGATACTAAACTG
TGACATACCGTATAAAGCGA

Product: DNA polymerase III PolC

Products: NA

Alternate protein names: PolIII

Number of amino acids: Translated: 1465; Mature: 1464

Protein sequence:

>1465_residues
MSDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFHFAFAAVLPIATYRELHDRLIRTFEAADIKVTFDIQA
AQVDYSDDLLQAYYQEAFEHAPCNSASFKSSFSKLKVTYEDDKLIIAAPGFVNNDHFRNNHLPNLVKQLEAFGFGILTID
MVSDQEMTEHLTKNFVSSRQALVKKAVQDNLEAQKSLEAMMPPVEEATPAPKFDYKERAAKRQAGFEKATITPMIEIETE
ENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSFALQKWAKDDEELRKFDMIAKGAWLRVQGNIETNPFTKSLTMNVQ
QVKEIVRHERKDLMPEGQKRVELHAHTNMSTMDALPTVESLIDTAAKWGHKAIAITDHANVQSFPHGYHRARKAGIKAIF
GLEANIVEDKVPISYEPVDMDLHEATYVVFDVETTGLSAMNNDLIQIAASKMFKGNIVEQFDEFIDPGHPLSAFTTELTG
ITDKHLQGAKPLVTVLKAFQDFCKDSILVAHNASFDVGFMNANYERHDLPKITQPVIDTLEFARNLYPEYKRHGLGPLTK
RFQVSLDHHHMANYDAEATGRLLFIFLKDAREKHGIKNLLQLNTDLVAEDSYKKARIKHATIYVQNQVGLKNMFKLVSLS
NIKYFEGVPRIPRTVLDAHREGLLLGTACSDGEVFDAVLTKGIDAAVDLARYYDFIEIMPPAIYQPLVVRELIKDQAGIE
QVIRDLIEVGKRAKKPVLATGNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGEGAQPAPLPKAHFRTTNEMLDEFAFL
GKDLAYQVVVQNTQDFADRIEEVEVVKGDLYTPYIDKAEETVAELTYQKAFEIYGNPLPDIIDLRIEKELTSILGNGFAV
IYLASQMLVNRSNERGYLVGSRGSVGSSFVATMIGITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKPCPKCGTPY
QKDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGDEYAFRAGTVGTVAEKTAYGFVKGYERDYGKFYRDA
EVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTASWQTTHFNFHDIDENVLKLDILGHDDPTMIRKL
QDLSGIDPITIPADDPGVMALFSGTEVLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVW
LGNAQDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIDAMRENNVPDWYIESCG
KIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIRAKAFELKTMSGGLDAVKARMEDITIKRKNNEATNVENDLF
TTLEIVNEMLERGFKFGKLDLYKSDAIEFQIKGDTLIPPFIALEGLGENVAKQIVKARQEGEFLSKMELRKRGGASSTLV
EKMDEMGILGNMPEDNQLSLFDDFF

Sequences:

>Translated_1465_residues
MSDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFHFAFAAVLPIATYRELHDRLIRTFEAADIKVTFDIQA
AQVDYSDDLLQAYYQEAFEHAPCNSASFKSSFSKLKVTYEDDKLIIAAPGFVNNDHFRNNHLPNLVKQLEAFGFGILTID
MVSDQEMTEHLTKNFVSSRQALVKKAVQDNLEAQKSLEAMMPPVEEATPAPKFDYKERAAKRQAGFEKATITPMIEIETE
ENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSFALQKWAKDDEELRKFDMIAKGAWLRVQGNIETNPFTKSLTMNVQ
QVKEIVRHERKDLMPEGQKRVELHAHTNMSTMDALPTVESLIDTAAKWGHKAIAITDHANVQSFPHGYHRARKAGIKAIF
GLEANIVEDKVPISYEPVDMDLHEATYVVFDVETTGLSAMNNDLIQIAASKMFKGNIVEQFDEFIDPGHPLSAFTTELTG
ITDKHLQGAKPLVTVLKAFQDFCKDSILVAHNASFDVGFMNANYERHDLPKITQPVIDTLEFARNLYPEYKRHGLGPLTK
RFQVSLDHHHMANYDAEATGRLLFIFLKDAREKHGIKNLLQLNTDLVAEDSYKKARIKHATIYVQNQVGLKNMFKLVSLS
NIKYFEGVPRIPRTVLDAHREGLLLGTACSDGEVFDAVLTKGIDAAVDLARYYDFIEIMPPAIYQPLVVRELIKDQAGIE
QVIRDLIEVGKRAKKPVLATGNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGEGAQPAPLPKAHFRTTNEMLDEFAFL
GKDLAYQVVVQNTQDFADRIEEVEVVKGDLYTPYIDKAEETVAELTYQKAFEIYGNPLPDIIDLRIEKELTSILGNGFAV
IYLASQMLVNRSNERGYLVGSRGSVGSSFVATMIGITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKPCPKCGTPY
QKDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGDEYAFRAGTVGTVAEKTAYGFVKGYERDYGKFYRDA
EVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTASWQTTHFNFHDIDENVLKLDILGHDDPTMIRKL
QDLSGIDPITIPADDPGVMALFSGTEVLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVW
LGNAQDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIDAMRENNVPDWYIESCG
KIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIRAKAFELKTMSGGLDAVKARMEDITIKRKNNEATNVENDLF
TTLEIVNEMLERGFKFGKLDLYKSDAIEFQIKGDTLIPPFIALEGLGENVAKQIVKARQEGEFLSKMELRKRGGASSTLV
EKMDEMGILGNMPEDNQLSLFDDFF
>Mature_1464_residues
SDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFHFAFAAVLPIATYRELHDRLIRTFEAADIKVTFDIQAA
QVDYSDDLLQAYYQEAFEHAPCNSASFKSSFSKLKVTYEDDKLIIAAPGFVNNDHFRNNHLPNLVKQLEAFGFGILTIDM
VSDQEMTEHLTKNFVSSRQALVKKAVQDNLEAQKSLEAMMPPVEEATPAPKFDYKERAAKRQAGFEKATITPMIEIETEE
NRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSFALQKWAKDDEELRKFDMIAKGAWLRVQGNIETNPFTKSLTMNVQQ
VKEIVRHERKDLMPEGQKRVELHAHTNMSTMDALPTVESLIDTAAKWGHKAIAITDHANVQSFPHGYHRARKAGIKAIFG
LEANIVEDKVPISYEPVDMDLHEATYVVFDVETTGLSAMNNDLIQIAASKMFKGNIVEQFDEFIDPGHPLSAFTTELTGI
TDKHLQGAKPLVTVLKAFQDFCKDSILVAHNASFDVGFMNANYERHDLPKITQPVIDTLEFARNLYPEYKRHGLGPLTKR
FQVSLDHHHMANYDAEATGRLLFIFLKDAREKHGIKNLLQLNTDLVAEDSYKKARIKHATIYVQNQVGLKNMFKLVSLSN
IKYFEGVPRIPRTVLDAHREGLLLGTACSDGEVFDAVLTKGIDAAVDLARYYDFIEIMPPAIYQPLVVRELIKDQAGIEQ
VIRDLIEVGKRAKKPVLATGNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGEGAQPAPLPKAHFRTTNEMLDEFAFLG
KDLAYQVVVQNTQDFADRIEEVEVVKGDLYTPYIDKAEETVAELTYQKAFEIYGNPLPDIIDLRIEKELTSILGNGFAVI
YLASQMLVNRSNERGYLVGSRGSVGSSFVATMIGITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKPCPKCGTPYQ
KDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGDEYAFRAGTVGTVAEKTAYGFVKGYERDYGKFYRDAE
VDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTASWQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQ
DLSGIDPITIPADDPGVMALFSGTEVLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWL
GNAQDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIDAMRENNVPDWYIESCGK
IKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIRAKAFELKTMSGGLDAVKARMEDITIKRKNNEATNVENDLFT
TLEIVNEMLERGFKFGKLDLYKSDAIEFQIKGDTLIPPFIALEGLGENVAKQIVKARQEGEFLSKMELRKRGGASSTLVE
KMDEMGILGNMPEDNQLSLFDDFF

Specific function: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity

COG id: COG2176

COG function: function code L; DNA polymerase III, alpha subunit (gram-positive type)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain

Homologues:

Organism=Escherichia coli, GI1786409, Length=147, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DPO3_STRP1 (P0C0B8)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_269933.1
- RefSeq:   YP_283035.1
- ProteinModelPortal:   P0C0B8
- EnsemblBacteria:   EBSTRT00000001545
- EnsemblBacteria:   EBSTRT00000028898
- GeneID:   3571226
- GeneID:   901636
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_1961
- KEGG:   spz:M5005_Spy_1672
- GeneTree:   EBGT00050000027831
- HOGENOM:   HBG617116
- OMA:   WKTTHFD
- ProtClustDB:   PRK00448
- BioCyc:   SPYO160490:SPY1961-MONOMER
- BioCyc:   SPYO293653:M5005_SPY1672-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00356
- InterPro:   IPR011708
- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR016195
- InterPro:   IPR006308
- InterPro:   IPR012337
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00479
- SMART:   SM00481
- TIGRFAMs:   TIGR00573
- TIGRFAMs:   TIGR01405

Pfam domain/function: PF07733 DNA_pol3_alpha; PF00929 Exonuc_X-T; PF02811 PHP; SSF50249 Nucleic_acid_OB; SSF89550 PHP-like; SSF53098 RNaseH_fold

EC number: =2.7.7.7

Molecular weight: Translated: 164670; Mature: 164539

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFHFAFAAVLPIATYRELH
CHHHHHHHHHHHCCCHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRLIRTFEAADIKVTFDIQAAQVDYSDDLLQAYYQEAFEHAPCNSASFKSSFSKLKVTYE
HHHHHHHCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHCHHHEEEEEE
DDKLIIAAPGFVNNDHFRNNHLPNLVKQLEAFGFGILTIDMVSDQEMTEHLTKNFVSSRQ
CCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHHHH
ALVKKAVQDNLEAQKSLEAMMPPVEEATPAPKFDYKERAAKRQAGFEKATITPMIEIETE
HHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHCCCCCEEECEEEEEEEC
ENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSFALQKWAKDDEELRKFDMIAKGAWL
CCEEEEEEEEEEEHHHHHHCCCEEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHCCEEE
RVQGNIETNPFTKSLTMNVQQVKEIVRHERKDLMPEGQKRVELHAHTNMSTMDALPTVES
EEECCCCCCCCCHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHH
LIDTAAKWGHKAIAITDHANVQSFPHGYHRARKAGIKAIFGLEANIVEDKVPISYEPVDM
HHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHCCCEEECCCCEEECCCCCCCCCCCCC
DLHEATYVVFDVETTGLSAMNNDLIQIAASKMFKGNIVEQFDEFIDPGHPLSAFTTELTG
CCCCCEEEEEEEECCCCHHHCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHCC
ITDKHLQGAKPLVTVLKAFQDFCKDSILVAHNASFDVGFMNANYERHDLPKITQPVIDTL
CCHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHH
EFARNLYPEYKRHGLGPLTKRFQVSLDHHHMANYDAEATGRLLFIFLKDAREKHGIKNLL
HHHHHHCHHHHHCCCCCCCHHHEEEECCHHCCCCCCCCCCCEEEEEEHHHHHHHHHHHHH
QLNTDLVAEDSYKKARIKHATIYVQNQVGLKNMFKLVSLSNIKYFEGVPRIPRTVLDAHR
HHCCCCCCCCCHHHHEEEEEEEEEECCCCHHHHHHHHHHCCCHHHCCCCCCHHHHHHHCC
EGLLLGTACSDGEVFDAVLTKGIDAAVDLARYYDFIEIMPPAIYQPLVVRELIKDQAGIE
CCEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHH
QVIRDLIEVGKRAKKPVLATGNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGEGAQPA
HHHHHHHHHHHHCCCCEEECCCEEEECCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCC
PLPKAHFRTTNEMLDEFAFLGKDLAYQVVVQNTQDFADRIEEVEVVKGDLYTPYIDKAEE
CCCHHHHHHHHHHHHHHHHHCCCCEEEHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHH
TVAELTYQKAFEIYGNPLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVG
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCCCEEEE
SRGSVGSSFVATMIGITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKPCPKCGTPY
CCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
QKDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGDEYAFRAGTVGTVAEK
CCCCCCCCHHHHCCCCCCCCCCEEECCCCCCCCCCCEEHHHHCCCCCEECCCCCCHHHHH
TAYGFVKGYERDYGKFYRDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQY
HHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCC
PADDVTASWQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPITIPADDPGVMA
CCCCCCCCEEEEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCEEECCCCCCEEE
LFSGTEVLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVW
EECCCEEEECCHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCEE
LGNAQDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERN
ECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCCC
GYIDAMRENNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIR
CCEEHHHCCCCCCHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
AKAFELKTMSGGLDAVKARMEDITIKRKNNEATNVENDLFTTLEIVNEMLERGFKFGKLD
HHEEEEEECCCCHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEE
LYKSDAIEFQIKGDTLIPPFIALEGLGENVAKQIVKARQEGEFLSKMELRKRGGASSTLV
EEECCCEEEEECCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
EKMDEMGILGNMPEDNQLSLFDDFF
HHHHHCCCCCCCCCCCCCCHHHCCC
>Mature Secondary Structure 
SDLFAKLMDQIEMPLDMRRSSAFSSADIIEVKVHSVSRLWEFHFAFAAVLPIATYRELH
HHHHHHHHHHHCCCHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRLIRTFEAADIKVTFDIQAAQVDYSDDLLQAYYQEAFEHAPCNSASFKSSFSKLKVTYE
HHHHHHHCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHCHHHEEEEEE
DDKLIIAAPGFVNNDHFRNNHLPNLVKQLEAFGFGILTIDMVSDQEMTEHLTKNFVSSRQ
CCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHHHHHH
ALVKKAVQDNLEAQKSLEAMMPPVEEATPAPKFDYKERAAKRQAGFEKATITPMIEIETE
HHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHHHHHHCCCCCEEECEEEEEEEC
ENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSFALQKWAKDDEELRKFDMIAKGAWL
CCEEEEEEEEEEEHHHHHHCCCEEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHCCEEE
RVQGNIETNPFTKSLTMNVQQVKEIVRHERKDLMPEGQKRVELHAHTNMSTMDALPTVES
EEECCCCCCCCCHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHH
LIDTAAKWGHKAIAITDHANVQSFPHGYHRARKAGIKAIFGLEANIVEDKVPISYEPVDM
HHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHCCCEEECCCCEEECCCCCCCCCCCCC
DLHEATYVVFDVETTGLSAMNNDLIQIAASKMFKGNIVEQFDEFIDPGHPLSAFTTELTG
CCCCCEEEEEEEECCCCHHHCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHCC
ITDKHLQGAKPLVTVLKAFQDFCKDSILVAHNASFDVGFMNANYERHDLPKITQPVIDTL
CCHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHH
EFARNLYPEYKRHGLGPLTKRFQVSLDHHHMANYDAEATGRLLFIFLKDAREKHGIKNLL
HHHHHHCHHHHHCCCCCCCHHHEEEECCHHCCCCCCCCCCCEEEEEEHHHHHHHHHHHHH
QLNTDLVAEDSYKKARIKHATIYVQNQVGLKNMFKLVSLSNIKYFEGVPRIPRTVLDAHR
HHCCCCCCCCCHHHHEEEEEEEEEECCCCHHHHHHHHHHCCCHHHCCCCCCHHHHHHHCC
EGLLLGTACSDGEVFDAVLTKGIDAAVDLARYYDFIEIMPPAIYQPLVVRELIKDQAGIE
CCEEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHH
QVIRDLIEVGKRAKKPVLATGNVHYLEPEEEIYREIIVRSLGQGAMINRTIGRGEGAQPA
HHHHHHHHHHHHCCCCEEECCCEEEECCHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCC
PLPKAHFRTTNEMLDEFAFLGKDLAYQVVVQNTQDFADRIEEVEVVKGDLYTPYIDKAEE
CCCHHHHHHHHHHHHHHHHHCCCCEEEHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHH
TVAELTYQKAFEIYGNPLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVG
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCCCEEEE
SRGSVGSSFVATMIGITEVNPMPPHYVCPSCQHSEFITDGSVGSGYDLPNKPCPKCGTPY
CCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
QKDGQDIPFETFLGFDGDKVPDIDLNFSGDDQPSAHLDVRDIFGDEYAFRAGTVGTVAEK
CCCCCCCCHHHHCCCCCCCCCCEEECCCCCCCCCCCEEHHHHCCCCCEECCCCCCHHHHH
TAYGFVKGYERDYGKFYRDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQY
HHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCC
PADDVTASWQTTHFNFHDIDENVLKLDILGHDDPTMIRKLQDLSGIDPITIPADDPGVMA
CCCCCCCCEEEEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCEEECCCCCCEEE
LFSGTEVLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVW
EECCCEEEECCHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCEE
LGNAQDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERN
ECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCCC
GYIDAMRENNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIR
CCEEHHHCCCCCCHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
AKAFELKTMSGGLDAVKARMEDITIKRKNNEATNVENDLFTTLEIVNEMLERGFKFGKLD
HHEEEEEECCCCHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEE
LYKSDAIEFQIKGDTLIPPFIALEGLGENVAKQIVKARQEGEFLSKMELRKRGGASSTLV
EEECCCEEEEECCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
EKMDEMGILGNMPEDNQLSLFDDFF
HHHHHCCCCCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11296296