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The map label for this gene is salR [H]

Identifier: 15675720

GI number: 15675720

Start: 1591272

End: 1591877

Strand: Reverse

Name: salR [H]

Synonym: SPy_1908

Alternate gene names: 15675720

Gene position: 1591877-1591272 (Counterclockwise)

Preceding gene: 15675721

Following gene: 15675716

Centisome position: 85.93

GC content: 30.86

Gene sequence:

>606_bases
ATGAAGATTTTATTAATTGATGACCACAGACTATTTGCAAAGAGTATCCAACTGTTATTCCAACAGTATGATGAAGTAGA
TGTCATAGATACGATTACTTCTCATTTTAACGATGTGACGATTGATTTGTCTAAGTACGATATTATATTGCTTGATATTA
ATTTAGCAAATATTTCTAAAGAAAATGGATTGGAGATAGCAAAAGAACTCATACAGTCTACTCCTCATTTGAAAGTTGTT
ATGTTGACAGGATATGTTAAATCAATCTATAGAGAGAGGGCAAAAAAAGTAGGAGCATACGGTTTTGTAGATAAAAATAT
AGACCCTAAACAACTCATTTCTATCTTAAAAAAAGTGGATTCTGGAAAAAAGTATTTTGAACAAATCGAATCTCAGGATT
ATGTTGAATCTTTAACTGACCAGGAAATAGCTATCTTAAATTTGAGTAAGAAAGGATTCTCTATAAAAGAAATAGAGGAA
ACGTTACAAATTAGTAGGAGAACAGTATTTAATCATTTGACCCACATCTACTCAAAGCTTTTGGTAAATAATAAGCAGGA
GGCTATCTACAAAGCCGAACAATTAGGGTATTTTATGGATTTCTGA

Upstream 100 bases:

>100_bases
CAAGAAACACTAGCAGCTTTTGATGGAGATCTAGAACTACAAATGGATACTAAACAATTTACTATCAGAATATTACTTCC
CATAGATTGGAAATTGTGTT

Downstream 100 bases:

>100_bases
GTTGCAGATAATCAAACGACATAAGTTTTACTTGTGTCGTTGCTAGGGATTTCCTGTTAAATACCCAGATTTAAACTCAT
TGTTTTTTTAGTTCTTTTTG

Product: putative response regulator of salavaricin regulon

Products: NA

Alternate protein names: Competence protein A [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MKILLIDDHRLFAKSIQLLFQQYDEVDVIDTITSHFNDVTIDLSKYDIILLDINLANISKENGLEIAKELIQSTPHLKVV
MLTGYVKSIYRERAKKVGAYGFVDKNIDPKQLISILKKVDSGKKYFEQIESQDYVESLTDQEIAILNLSKKGFSIKEIEE
TLQISRRTVFNHLTHIYSKLLVNNKQEAIYKAEQLGYFMDF

Sequences:

>Translated_201_residues
MKILLIDDHRLFAKSIQLLFQQYDEVDVIDTITSHFNDVTIDLSKYDIILLDINLANISKENGLEIAKELIQSTPHLKVV
MLTGYVKSIYRERAKKVGAYGFVDKNIDPKQLISILKKVDSGKKYFEQIESQDYVESLTDQEIAILNLSKKGFSIKEIEE
TLQISRRTVFNHLTHIYSKLLVNNKQEAIYKAEQLGYFMDF
>Mature_201_residues
MKILLIDDHRLFAKSIQLLFQQYDEVDVIDTITSHFNDVTIDLSKYDIILLDINLANISKENGLEIAKELIQSTPHLKVV
MLTGYVKSIYRERAKKVGAYGFVDKNIDPKQLISILKKVDSGKKYFEQIESQDYVESLTDQEIAILNLSKKGFSIKEIEE
TLQISRRTVFNHLTHIYSKLLVNNKQEAIYKAEQLGYFMDF

Specific function: Response regulator in the two-component regulatory system ComP/ComA involved in a major quorum response pathway that regulates the development of genetic competence. Regulates directly the expression of over 20 genes, including genes of the srfA operon, d

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=192, Percent_Identity=26.5625, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786747, Length=193, Percent_Identity=28.4974093264249, Blast_Score=71, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23296; Mature: 23296

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILLIDDHRLFAKSIQLLFQQYDEVDVIDTITSHFNDVTIDLSKYDIILLDINLANISK
CEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCEEEEEEEEEHHHCCC
ENGLEIAKELIQSTPHLKVVMLTGYVKSIYRERAKKVGAYGFVDKNIDPKQLISILKKVD
CCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHC
SGKKYFEQIESQDYVESLTDQEIAILNLSKKGFSIKEIEETLQISRRTVFNHLTHIYSKL
CHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LVNNKQEAIYKAEQLGYFMDF
HHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKILLIDDHRLFAKSIQLLFQQYDEVDVIDTITSHFNDVTIDLSKYDIILLDINLANISK
CEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCEEEEEEEEEHHHCCC
ENGLEIAKELIQSTPHLKVVMLTGYVKSIYRERAKKVGAYGFVDKNIDPKQLISILKKVD
CCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHC
SGKKYFEQIESQDYVESLTDQEIAILNLSKKGFSIKEIEETLQISRRTVFNHLTHIYSKL
CHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LVNNKQEAIYKAEQLGYFMDF
HHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2507523; 9274030; 9384377 [H]