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The map label for this gene is rnhC

Identifier: 15675667

GI number: 15675667

Start: 1526806

End: 1527708

Strand: Direct

Name: rnhC

Synonym: SPy_1841

Alternate gene names: 15675667

Gene position: 1526806-1527708 (Clockwise)

Preceding gene: 15675661

Following gene: 15675668

Centisome position: 82.42

GC content: 36.99

Gene sequence:

>903_bases
ATGAATACCTTAGTTTTGAAAATAGATGCTATACTGAGTAAACATTTAAAAAAACAGCTAGCCCCCTACACCATCAGTAG
CCAAAATACCTATGTAGCCTTTGCTGCTAAAAAAAATGGGGTTACTGTTTTGCTGTACAAATCCGGAAAATTAGTTCTCC
AGGGAAACGGTGCAAATGCTTTAGCTCAAGAGCTTAATCTTCCAGTAGCTAAGACAGTTTTTGAAGCAAGCAACAATAGC
CAAGATATACCTATAATCGGCAGTGATGAGGTGGGTAATGGCTCTTATTTTGGTGGGATTGCTGTTGTGGCAAGTTTTGT
CGATCCTAAAGATCATTCCTTCCTGAAAAAGCTTGGGGTTGATGATTCTAAAAAATTATCGGATAAAACCATTCAACAGA
TTGCGCCTCTGTTAGAGAAACAAATACCTCATCAATCACTTCTCCTATCACCTAAAAAATATAACGAATTGGTTGGTAAA
AGTAAACCATATAATGCCATTTCTATCAAAGTTGCTCTTCATAACCAAGCTATTTTTTTGTTGTTACAAAAAGGCATTCA
ACCTAAACAAATTGTTATTGATGCTTTCACTAGCCAATCAAATTATGAAAAGCATCTAAAAAAGGAAAAAAACCATTTCC
CAAATCCTCTAACCTTTCAAGAAAAGGCAGAAAGTCACTATTTGGCTGTGGCTGTTAGCTCTATCATTGCTAGAAATCTA
TTTTTAGACAATCTCGATCAATTAGGTCAAGATTTAGGTTACCAACTCCCAAGCGGTGCTGGTTCAGCTTCAGATAAAGT
TGCTAGCCAACTCTTAGCCGCTTATGGTATGTCTAGCTTAGAATATAGTGCTAAACTTCACTTCGCCAACACTCACAAAG
CGCAAGCGCTTCTCACTAAATAA

Upstream 100 bases:

>100_bases
CCATTGCCCTAACCCGTCTAAACATTCGAGTCTCTGTTTTCTTTGTTAAATAAACTTATGAATTAACCATAGTCAACTAT
TTTATGTTAAAATAATTATT

Downstream 100 bases:

>100_bases
AAGGAATCATATGAAACAGTTTATTAAAGAATGGGGCCCATTCACTCTCTTTTTAATTCTCTTTGGTCTATCTCGTCTTT
TTTTGTGGCAGGCTGTTAAA

Product: ribonuclease HIII

Products: NA

Alternate protein names: RNase HIII

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MNTLVLKIDAILSKHLKKQLAPYTISSQNTYVAFAAKKNGVTVLLYKSGKLVLQGNGANALAQELNLPVAKTVFEASNNS
QDIPIIGSDEVGNGSYFGGIAVVASFVDPKDHSFLKKLGVDDSKKLSDKTIQQIAPLLEKQIPHQSLLLSPKKYNELVGK
SKPYNAISIKVALHNQAIFLLLQKGIQPKQIVIDAFTSQSNYEKHLKKEKNHFPNPLTFQEKAESHYLAVAVSSIIARNL
FLDNLDQLGQDLGYQLPSGAGSASDKVASQLLAAYGMSSLEYSAKLHFANTHKAQALLTK

Sequences:

>Translated_300_residues
MNTLVLKIDAILSKHLKKQLAPYTISSQNTYVAFAAKKNGVTVLLYKSGKLVLQGNGANALAQELNLPVAKTVFEASNNS
QDIPIIGSDEVGNGSYFGGIAVVASFVDPKDHSFLKKLGVDDSKKLSDKTIQQIAPLLEKQIPHQSLLLSPKKYNELVGK
SKPYNAISIKVALHNQAIFLLLQKGIQPKQIVIDAFTSQSNYEKHLKKEKNHFPNPLTFQEKAESHYLAVAVSSIIARNL
FLDNLDQLGQDLGYQLPSGAGSASDKVASQLLAAYGMSSLEYSAKLHFANTHKAQALLTK
>Mature_300_residues
MNTLVLKIDAILSKHLKKQLAPYTISSQNTYVAFAAKKNGVTVLLYKSGKLVLQGNGANALAQELNLPVAKTVFEASNNS
QDIPIIGSDEVGNGSYFGGIAVVASFVDPKDHSFLKKLGVDDSKKLSDKTIQQIAPLLEKQIPHQSLLLSPKKYNELVGK
SKPYNAISIKVALHNQAIFLLLQKGIQPKQIVIDAFTSQSNYEKHLKKEKNHFPNPLTFQEKAESHYLAVAVSSIIARNL
FLDNLDQLGQDLGYQLPSGAGSASDKVASQLLAAYGMSSLEYSAKLHFANTHKAQALLTK

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG1039

COG function: function code L; Ribonuclease HIII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family. RnhC subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH3_STRP1 (P66677)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_269841.1
- RefSeq:   YP_282927.1
- ProteinModelPortal:   P66677
- SMR:   P66677
- EnsemblBacteria:   EBSTRT00000000909
- EnsemblBacteria:   EBSTRT00000028656
- GeneID:   3571331
- GeneID:   902058
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_1841
- KEGG:   spz:M5005_Spy_1564
- GeneTree:   EBGT00050000028041
- HOGENOM:   HBG288559
- OMA:   ASIIARY
- ProtClustDB:   PRK00996
- BioCyc:   SPYO160490:SPY1841-MONOMER
- BioCyc:   SPYO293653:M5005_SPY1564-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00053
- InterPro:   IPR001352
- InterPro:   IPR004641
- InterPro:   IPR012337
- PIRSF:   PIRSF037748
- TIGRFAMs:   TIGR00716

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 32655; Mature: 32655

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTLVLKIDAILSKHLKKQLAPYTISSQNTYVAFAAKKNGVTVLLYKSGKLVLQGNGANA
CCEEEEEHHHHHHHHHHHHCCCEEECCCCEEEEEEECCCCEEEEEEECCEEEEECCCCHH
LAQELNLPVAKTVFEASNNSQDIPIIGSDEVGNGSYFGGIAVVASFVDPKDHSFLKKLGV
HHHHHCCCHHHHHHHCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCC
DDSKKLSDKTIQQIAPLLEKQIPHQSLLLSPKKYNELVGKSKPYNAISIKVALHNQAIFL
CCCHHHHHHHHHHHHHHHHHHCCHHHHEECCHHHHHHHCCCCCCCEEEEEEEECCHHHHH
LLQKGIQPKQIVIDAFTSQSNYEKHLKKEKNHFPNPLTFQEKAESHYLAVAVSSIIARNL
HHHHCCCCHHEEEEECCCCCHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHH
FLDNLDQLGQDLGYQLPSGAGSASDKVASQLLAAYGMSSLEYSAKLHFANTHKAQALLTK
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHCCCC
>Mature Secondary Structure
MNTLVLKIDAILSKHLKKQLAPYTISSQNTYVAFAAKKNGVTVLLYKSGKLVLQGNGANA
CCEEEEEHHHHHHHHHHHHCCCEEECCCCEEEEEEECCCCEEEEEEECCEEEEECCCCHH
LAQELNLPVAKTVFEASNNSQDIPIIGSDEVGNGSYFGGIAVVASFVDPKDHSFLKKLGV
HHHHHCCCHHHHHHHCCCCCCCCCEECCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCC
DDSKKLSDKTIQQIAPLLEKQIPHQSLLLSPKKYNELVGKSKPYNAISIKVALHNQAIFL
CCCHHHHHHHHHHHHHHHHHHCCHHHHEECCHHHHHHHCCCCCCCEEEEEEEECCHHHHH
LLQKGIQPKQIVIDAFTSQSNYEKHLKKEKNHFPNPLTFQEKAESHYLAVAVSSIIARNL
HHHHCCCCHHEEEEECCCCCHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHH
FLDNLDQLGQDLGYQLPSGAGSASDKVASQLLAAYGMSSLEYSAKLHFANTHKAQALLTK
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296