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The map label for this gene is scrA [H]

Identifier: 15675645

GI number: 15675645

Start: 1505928

End: 1507790

Strand: Reverse

Name: scrA [H]

Synonym: SPy_1815

Alternate gene names: 15675645

Gene position: 1507790-1505928 (Counterclockwise)

Preceding gene: 15675648

Following gene: 15675644

Centisome position: 81.39

GC content: 43.75

Gene sequence:

>1863_bases
ATGGATAATCGTCAGATTGCAGCTGAAGTGATTGAGGCTTTAGGTGGCCGAGAAAATGTGAGAAGTGTTGCCCACTGTGC
AACTCGCCTTCGCGTGATGGTTTATGATGAAGGAAAGATTGATAAGGAAAAAGCAGAAGCTATTGACAAGGTTAAAGGAG
CTTTCTTTAACTCTGGTCAATATCAGATGATTTTTGGAACTGGTACCGTTAATAACATTTATGACGAAGTTGTTGCTCTT
GGTTTACCCACGTCATCAACCAGTGAGCAAAAGGCAGAAGCAGGCAAACATGGCAATATCTTCCAACGGGCGATTCGTAC
GTTTGGAGATGTCTTTGTTCCCATTATTCCAGCTATTGTAGCAACGGGTCTCTTTATGGGGGTTCGTGGTTTGGTGACCC
AGCCAGCTATTATGGATTTATTTGGGGTGCATGAGTACGGGGAAAATTTTCTCATGTACACTCGTATTCTAACGGATACA
GCCTTTGTCTACTTGCCAGCTTTGGTGGCTTGGTCAGCCTTTAGGGTCTTTGGGGGTAATCCTATTATCGGTATTGTTTT
AGGATTGATGCTGGTTTCCAATGAGTTGCCTAATGCTTGGGTAGTTGCCTCTGGTGGAGATGTTAAGCCGCTAACCTTCT
TTGGATTTGTTCCTGTTGTTGGTTATCAAGGTACCGTTTTACCCGCCTTCTTTGTTGGTCTGGTAGGAGCTAAGTTGGAG
AAATGGTTGCACAAAAAGGTTCCAGAAGCTTTGGACTTATTGGTCACACCGTTTTTAACGTTTGCTATTATGAGTACCTT
GGGACTATTTGTGATTGGACCAGTTTTCCATTCTCTTGAAAACCTTGTTCTGGCTGGGACACAGGCCGTCTTGCATTTGC
CGTTTGGCATTGCAGGCTTGATTGTTGGGGGAATCCAACAATTAATCGTAGTGACTGGTATTCACCATATCTTTAACTTC
CTAGAAGCGCAGCTGATTGCCAATACCGGAAAAGATCCTTTCAATGCTTACCTAACAGCAGCAACAGCTGCTCAAGCTGG
AGCTACCTTAGCTGTTGCTGTTAAAACCAAATCAACAAAACTAAAAGGTCTGGCCTTTCCATCAACCTTGTCAGCTCTTT
TAGGGATTACTGAACCAGCTATTTTTGGGGTCAACCTCCGTTATCCAAAAGTCTTTGTTTCAGGTCTTATTGGTGGTGCC
TTAGGTGGTTGGGTCGCTGGGCTCTTTGGCATTGCAGGAACTGGTTTTGGGATTACGGTCTTACCAGGAACTCTCCTTTA
CTTGAATGGCCAATTATTACAATACCTTGTGACTATGCTTGTCGGTCTTGGGGTAGCCTTTGCAATTGCTTATACTTGGG
GTTATCAAGATAGAGAAACCCTTCCGTTACCAGCTGTCGAAGTTGATCAAACGGCTGATCAGCCAGCCTTAGCAGAGGAA
ACTTTATATAGTCCTTTGAATGGAACAGTTGTAGACTTATCTGCGGTTTCAGACCCTGTTTTTTCATCAGGTGCTATGGG
TCAAGGCTTAGCAATTAAGCCAGAAGATAATACCCTATACTCACCAGTTGATGGTAAAGTTGAAATTGTCTTTGAAACAG
GTCATGCCTATGCTATAACGTCAAGTCAAGGAGCAGAAGTGTTACTTCATATTGGTATTGATACCGAGTCGATGGCAGGA
GATGGCTTTGAATCTCTTGTAGCAGTAGGTCAGGCGGTTAAAAAAGGGGATCTTCTTGGACACTTTGATCCTAGCAAGAT
TGCAGAAGCTGGACTAGATGACACCACCATGATGATTGTGAGCAATATCGCTGACTATCAAAGCGTGGACATTCTTGCTC
AAGGACATGTTTTGAGGTGGTGA

Upstream 100 bases:

>100_bases
GTGTAGCGGATTCACTAGCGTTGGTCCTGCACATTCTTAGCCACAAAGCTGGCAGAATGGATGAGGGACTAACACCAAAT
GAAAAAGGAGACTTTTAGGC

Downstream 100 bases:

>100_bases
TCAAGTGGCACTTATCAAATAAGGTCAAAAGAGCTAACTAAGCAGCTCTTTTGTCCTGCCATGGATGGCAGGTTGGCAAA
AAAATGAGAAAAGCCTAAAA

Product: PTS system sucrose-specific transporter subunit IIABC

Products: NA

Alternate protein names: EIIBCA-Scr; EII-Scr; Sucrose-specific phosphotransferase enzyme IIB component; PTS system sucrose-specific EIIB component; Sucrose permease IIC component; PTS system sucrose-specific EIIC component; Sucrose-specific phosphotransferase enzyme IIA component; PTS system sucrose-specific EIIA component [H]

Number of amino acids: Translated: 620; Mature: 620

Protein sequence:

>620_residues
MDNRQIAAEVIEALGGRENVRSVAHCATRLRVMVYDEGKIDKEKAEAIDKVKGAFFNSGQYQMIFGTGTVNNIYDEVVAL
GLPTSSTSEQKAEAGKHGNIFQRAIRTFGDVFVPIIPAIVATGLFMGVRGLVTQPAIMDLFGVHEYGENFLMYTRILTDT
AFVYLPALVAWSAFRVFGGNPIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVPVVGYQGTVLPAFFVGLVGAKLE
KWLHKKVPEALDLLVTPFLTFAIMSTLGLFVIGPVFHSLENLVLAGTQAVLHLPFGIAGLIVGGIQQLIVVTGIHHIFNF
LEAQLIANTGKDPFNAYLTAATAAQAGATLAVAVKTKSTKLKGLAFPSTLSALLGITEPAIFGVNLRYPKVFVSGLIGGA
LGGWVAGLFGIAGTGFGITVLPGTLLYLNGQLLQYLVTMLVGLGVAFAIAYTWGYQDRETLPLPAVEVDQTADQPALAEE
TLYSPLNGTVVDLSAVSDPVFSSGAMGQGLAIKPEDNTLYSPVDGKVEIVFETGHAYAITSSQGAEVLLHIGIDTESMAG
DGFESLVAVGQAVKKGDLLGHFDPSKIAEAGLDDTTMMIVSNIADYQSVDILAQGHVLRW

Sequences:

>Translated_620_residues
MDNRQIAAEVIEALGGRENVRSVAHCATRLRVMVYDEGKIDKEKAEAIDKVKGAFFNSGQYQMIFGTGTVNNIYDEVVAL
GLPTSSTSEQKAEAGKHGNIFQRAIRTFGDVFVPIIPAIVATGLFMGVRGLVTQPAIMDLFGVHEYGENFLMYTRILTDT
AFVYLPALVAWSAFRVFGGNPIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVPVVGYQGTVLPAFFVGLVGAKLE
KWLHKKVPEALDLLVTPFLTFAIMSTLGLFVIGPVFHSLENLVLAGTQAVLHLPFGIAGLIVGGIQQLIVVTGIHHIFNF
LEAQLIANTGKDPFNAYLTAATAAQAGATLAVAVKTKSTKLKGLAFPSTLSALLGITEPAIFGVNLRYPKVFVSGLIGGA
LGGWVAGLFGIAGTGFGITVLPGTLLYLNGQLLQYLVTMLVGLGVAFAIAYTWGYQDRETLPLPAVEVDQTADQPALAEE
TLYSPLNGTVVDLSAVSDPVFSSGAMGQGLAIKPEDNTLYSPVDGKVEIVFETGHAYAITSSQGAEVLLHIGIDTESMAG
DGFESLVAVGQAVKKGDLLGHFDPSKIAEAGLDDTTMMIVSNIADYQSVDILAQGHVLRW
>Mature_620_residues
MDNRQIAAEVIEALGGRENVRSVAHCATRLRVMVYDEGKIDKEKAEAIDKVKGAFFNSGQYQMIFGTGTVNNIYDEVVAL
GLPTSSTSEQKAEAGKHGNIFQRAIRTFGDVFVPIIPAIVATGLFMGVRGLVTQPAIMDLFGVHEYGENFLMYTRILTDT
AFVYLPALVAWSAFRVFGGNPIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVPVVGYQGTVLPAFFVGLVGAKLE
KWLHKKVPEALDLLVTPFLTFAIMSTLGLFVIGPVFHSLENLVLAGTQAVLHLPFGIAGLIVGGIQQLIVVTGIHHIFNF
LEAQLIANTGKDPFNAYLTAATAAQAGATLAVAVKTKSTKLKGLAFPSTLSALLGITEPAIFGVNLRYPKVFVSGLIGGA
LGGWVAGLFGIAGTGFGITVLPGTLLYLNGQLLQYLVTMLVGLGVAFAIAYTWGYQDRETLPLPAVEVDQTADQPALAEE
TLYSPLNGTVVDLSAVSDPVFSSGAMGQGLAIKPEDNTLYSPVDGKVEIVFETGHAYAITSSQGAEVLLHIGIDTESMAG
DGFESLVAVGQAVKKGDLLGHFDPSKIAEAGLDDTTMMIVSNIADYQSVDILAQGHVLRW

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1790159, Length=627, Percent_Identity=29.8245614035088, Blast_Score=254, Evalue=8e-69,
Organism=Escherichia coli, GI2367362, Length=433, Percent_Identity=30.9468822170901, Blast_Score=208, Evalue=9e-55,
Organism=Escherichia coli, GI48994906, Length=487, Percent_Identity=28.1314168377823, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1788769, Length=439, Percent_Identity=27.3348519362187, Blast_Score=122, Evalue=7e-29,
Organism=Escherichia coli, GI1786894, Length=143, Percent_Identity=36.3636363636364, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1788757, Length=128, Percent_Identity=37.5, Blast_Score=99, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR010973 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 65726; Mature: 65726

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS51093 PTS_EIIA_TYPE_1 ; PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNRQIAAEVIEALGGRENVRSVAHCATRLRVMVYDEGKIDKEKAEAIDKVKGAFFNSGQ
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHCCCCC
YQMIFGTGTVNNIYDEVVALGLPTSSTSEQKAEAGKHGNIFQRAIRTFGDVFVPIIPAIV
EEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
ATGLFMGVRGLVTQPAIMDLFGVHEYGENFLMYTRILTDTAFVYLPALVAWSAFRVFGGN
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVPVVGYQGTVLPAFFVGLVGAKLE
CHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
KWLHKKVPEALDLLVTPFLTFAIMSTLGLFVIGPVFHSLENLVLAGTQAVLHLPFGIAGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCHHHHHH
IVGGIQQLIVVTGIHHIFNFLEAQLIANTGKDPFNAYLTAATAAQAGATLAVAVKTKSTK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCC
LKGLAFPSTLSALLGITEPAIFGVNLRYPKVFVSGLIGGALGGWVAGLFGIAGTGFGITV
CCCCCCHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
LPGTLLYLNGQLLQYLVTMLVGLGVAFAIAYTWGYQDRETLPLPAVEVDQTADQPALAEE
CCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCHHHH
TLYSPLNGTVVDLSAVSDPVFSSGAMGQGLAIKPEDNTLYSPVDGKVEIVFETGHAYAIT
HHCCCCCCCEEEECCCCCCCCCCCCCCCCCEECCCCCCEECCCCCEEEEEEECCCEEEEE
SSQGAEVLLHIGIDTESMAGDGFESLVAVGQAVKKGDLLGHFDPSKIAEAGLDDTTMMIV
CCCCCEEEEEECCCCHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCHHHHHH
SNIADYQSVDILAQGHVLRW
HHHCCHHHHHEEECCCEECC
>Mature Secondary Structure
MDNRQIAAEVIEALGGRENVRSVAHCATRLRVMVYDEGKIDKEKAEAIDKVKGAFFNSGQ
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHCCCCC
YQMIFGTGTVNNIYDEVVALGLPTSSTSEQKAEAGKHGNIFQRAIRTFGDVFVPIIPAIV
EEEEEECCCHHHHHHHHHHCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
ATGLFMGVRGLVTQPAIMDLFGVHEYGENFLMYTRILTDTAFVYLPALVAWSAFRVFGGN
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVPVVGYQGTVLPAFFVGLVGAKLE
CHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
KWLHKKVPEALDLLVTPFLTFAIMSTLGLFVIGPVFHSLENLVLAGTQAVLHLPFGIAGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCHHHHHH
IVGGIQQLIVVTGIHHIFNFLEAQLIANTGKDPFNAYLTAATAAQAGATLAVAVKTKSTK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEEEECCCC
LKGLAFPSTLSALLGITEPAIFGVNLRYPKVFVSGLIGGALGGWVAGLFGIAGTGFGITV
CCCCCCHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
LPGTLLYLNGQLLQYLVTMLVGLGVAFAIAYTWGYQDRETLPLPAVEVDQTADQPALAEE
CCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCHHHH
TLYSPLNGTVVDLSAVSDPVFSSGAMGQGLAIKPEDNTLYSPVDGKVEIVFETGHAYAIT
HHCCCCCCCEEEECCCCCCCCCCCCCCCCCEECCCCCCEECCCCCEEEEEEECCCEEEEE
SSQGAEVLLHIGIDTESMAGDGFESLVAVGQAVKKGDLLGHFDPSKIAEAGLDDTTMMIV
CCCCCEEEEEECCCCHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCHHHHHH
SNIADYQSVDILAQGHVLRW
HHHCCHHHHHEEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2536656; 12397186; 8336109 [H]