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The map label for this gene is acpS

Identifier: 15675638

GI number: 15675638

Start: 1496040

End: 1496396

Strand: Reverse

Name: acpS

Synonym: SPy_1804

Alternate gene names: 15675638

Gene position: 1496396-1496040 (Counterclockwise)

Preceding gene: 15675639

Following gene: 15675637

Centisome position: 80.78

GC content: 36.13

Gene sequence:

>357_bases
ATGATTGTTGGACATGGAATAGACTTACAAGAGATTTCAGCTATTGAAAAAGTTTATCAAAGAAATCCTCGCTTTGCTCA
AAAAATTTTAACTGAGCAGGAATTGGCTATTTTTGAGAGTTTTCCTTACAAACGTCGACTCAACTATTTGGCAGGACGCT
GGTCAGGTAAGGAAGCTTTTGCTAAGGCTATAGGGACAGGTATTGGGCGGTTAACCTTTCAAGATATTGAGATTTTAAAT
GATGTTAGAGGATGTCCCATTCTGACAAAATCTCCGTTTAAAGGAAATAGTTTTATTAGCATCTCACATAGTGGCAATTA
TGTACAGGCTAGTGTTATTTTGGAGGATAAAAAATGA

Upstream 100 bases:

>100_bases
GGACAAAGTTAGGTATATAGAAAGAAGCTGAGAATAATTCTCAGCTTCTCACTGTTTAAATCTTCTAACATTAAGATGAA
ATAAGGTTTGGTGGAAAGTA

Downstream 100 bases:

>100_bases
TTTCAAGTTTCCATCGCCCAACAGTTGCAAGGGTCAACTTACAAGCTATTAAGGAGAATGTTGCCAGTGTTCAAAAGCAT
ATTCCACTAGGGGTAAAAAC

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 118; Mature: 118

Protein sequence:

>118_residues
MIVGHGIDLQEISAIEKVYQRNPRFAQKILTEQELAIFESFPYKRRLNYLAGRWSGKEAFAKAIGTGIGRLTFQDIEILN
DVRGCPILTKSPFKGNSFISISHSGNYVQASVILEDKK

Sequences:

>Translated_118_residues
MIVGHGIDLQEISAIEKVYQRNPRFAQKILTEQELAIFESFPYKRRLNYLAGRWSGKEAFAKAIGTGIGRLTFQDIEILN
DVRGCPILTKSPFKGNSFISISHSGNYVQASVILEDKK
>Mature_118_residues
MIVGHGIDLQEISAIEKVYQRNPRFAQKILTEQELAIFESFPYKRRLNYLAGRWSGKEAFAKAIGTGIGRLTFQDIEILN
DVRGCPILTKSPFKGNSFISISHSGNYVQASVILEDKK

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=125, Percent_Identity=34.4, Blast_Score=61, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_STRP1 (Q99Y97)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_269812.1
- RefSeq:   YP_282896.1
- ProteinModelPortal:   Q99Y97
- SMR:   Q99Y97
- EnsemblBacteria:   EBSTRT00000000545
- EnsemblBacteria:   EBSTRT00000028625
- GeneID:   3571378
- GeneID:   902029
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_1804
- KEGG:   spz:M5005_Spy_1533
- GeneTree:   EBGT00050000027655
- HOGENOM:   HBG734479
- OMA:   VHVSITH
- ProtClustDB:   PRK00070
- BioCyc:   SPYO160490:SPY1804-MONOMER
- BioCyc:   SPYO293653:M5005_SPY1533-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 13289; Mature: 13289

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVGHGIDLQEISAIEKVYQRNPRFAQKILTEQELAIFESFPYKRRLNYLAGRWSGKEAF
CEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHH
AKAIGTGIGRLTFQDIEILNDVRGCPILTKSPFKGNSFISISHSGNYVQASVILEDKK
HHHHHCCCCCHHHHHHHHHHHCCCCCCEECCCCCCCCEEEEECCCCEEEEEEEEECCC
>Mature Secondary Structure
MIVGHGIDLQEISAIEKVYQRNPRFAQKILTEQELAIFESFPYKRRLNYLAGRWSGKEAF
CEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHH
AKAIGTGIGRLTFQDIEILNDVRGCPILTKSPFKGNSFISISHSGNYVQASVILEDKK
HHHHHCCCCCHHHHHHHHHHHCCCCCCEECCCCCCCCEEEEECCCCEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296