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The map label for this gene is yfbQ [C]

Identifier: 15675619

GI number: 15675619

Start: 1470055

End: 1471269

Strand: Reverse

Name: yfbQ [C]

Synonym: SPy_1779

Alternate gene names: 15675619

Gene position: 1471269-1470055 (Counterclockwise)

Preceding gene: 15675621

Following gene: 15675618

Centisome position: 79.42

GC content: 39.09

Gene sequence:

>1215_bases
ATGAAAATTATTGAAAAATCATCAAAATTAGAACATGTTGCCTATGATATTCGAGGGCCTGTTTTGGATGAAGCTAATCG
CATGATTGCGAGTGGTGAAAAAATTCTGCGTTTAAATACTGGCAATCCTGCTGCTTTTGGTTTTGAAGCACCAGATGAAG
TGATTCGTGATTTAATTGTCAACGCGAGGCTAAGTGAGGGCTATTCTGACAGTAAAGGGATTTTTTCAGCGCGTAAGGCT
ATCATGCAGTATTGCCAACTCAAGGGCTTCCCAGATGTTGACATTGAAGATATTTATTTGGGAAATGGCGTGTCAGAGTT
GATATCCATATCCCTTCAAGCTTTGCTAGATAATGGCGATGAAGTTTTAGTACCAATGCCGGATTATCCTTTATGGACGG
CTTGTGTGAGTCTTGGTGGAGGAAAAGCGGTCCATTATCTTTGTGATGAAGAAGCTGGTTGGTATCCTGATATTGCTGAT
ATCAAATCAAAAATCACGAGTCGCACCAAAGCTATTGTGGTCATCAATCCTAATAACCCAACAGGAGCCCTTTATCCTAA
GGAGATTTTAGAAGACATCGTTGCTTTGGCAAGAGAACACCAGCTGATTATTTTTGCCGATGAAATCTATGATCGTTTGG
TGATGGATGGTAAAGAGCATATTGCTATTGCAAGTTTGGCACCTGATGTTTTTTGTGTATCTATGAATGGTCTTTCCAAA
TCTCATCGTATTGCTGGTTTTCGTGTTGGATGGATGGTCTTATCAGGTCCTAAAGACCATGTTAAAGGTTACATTGAAGG
GTTAAACATGCTTGCCAATATGCGGTTATGCTCCAATGTTTTAGCCCAACAAGTTGTTCAAACTTCCTTAGGAGGTCATC
AATCAGTTGATGCACTGTTACTGCCAGGAGGGCGTATTTTTGAGCAACGTAATTTTATTTATGAAGCTATTAATGCTATC
CCTGGCTTATCGGCAGTTAAACCTGAAGCAGGTCTTTATTTATTTCCGAAAATTGATCGTCAGATGTATCGTATTGATGA
TGATGAAGAATTTGTCTTACAGTTATTAAAGCAAGAAAAAGTGATGTTGGTACATGGACGTGGTTTTAACTGGAAAGATC
CAGATCACTTCCGTATTGTTTACCTACCAAGTGTAGAAGAATTAGAAGATGTCCAAGAAAAGATTACACGTGTCTTATAC
CAGTATAGACGTTAA

Upstream 100 bases:

>100_bases
ACCTGTGTTAAAACGATTAGCTGTCCTAAGCTTTGATGGATAAATTCTTTCTATTTTAAGTATTTTGGTTTATAATATGG
AATACGAGGTGTATGAGACT

Downstream 100 bases:

>100_bases
TGCAATGCTCATCTTTGATTAATAAAAATAGCGTTTCTTAAAAGAATGTGACCCTATGCTCTAACAAGCTAGTGCTTATC
TCCTTTAAATGAAGTGATAA

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MKIIEKSSKLEHVAYDIRGPVLDEANRMIASGEKILRLNTGNPAAFGFEAPDEVIRDLIVNARLSEGYSDSKGIFSARKA
IMQYCQLKGFPDVDIEDIYLGNGVSELISISLQALLDNGDEVLVPMPDYPLWTACVSLGGGKAVHYLCDEEAGWYPDIAD
IKSKITSRTKAIVVINPNNPTGALYPKEILEDIVALAREHQLIIFADEIYDRLVMDGKEHIAIASLAPDVFCVSMNGLSK
SHRIAGFRVGWMVLSGPKDHVKGYIEGLNMLANMRLCSNVLAQQVVQTSLGGHQSVDALLLPGGRIFEQRNFIYEAINAI
PGLSAVKPEAGLYLFPKIDRQMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKDPDHFRIVYLPSVEELEDVQEKITRVLY
QYRR

Sequences:

>Translated_404_residues
MKIIEKSSKLEHVAYDIRGPVLDEANRMIASGEKILRLNTGNPAAFGFEAPDEVIRDLIVNARLSEGYSDSKGIFSARKA
IMQYCQLKGFPDVDIEDIYLGNGVSELISISLQALLDNGDEVLVPMPDYPLWTACVSLGGGKAVHYLCDEEAGWYPDIAD
IKSKITSRTKAIVVINPNNPTGALYPKEILEDIVALAREHQLIIFADEIYDRLVMDGKEHIAIASLAPDVFCVSMNGLSK
SHRIAGFRVGWMVLSGPKDHVKGYIEGLNMLANMRLCSNVLAQQVVQTSLGGHQSVDALLLPGGRIFEQRNFIYEAINAI
PGLSAVKPEAGLYLFPKIDRQMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKDPDHFRIVYLPSVEELEDVQEKITRVLY
QYRR
>Mature_404_residues
MKIIEKSSKLEHVAYDIRGPVLDEANRMIASGEKILRLNTGNPAAFGFEAPDEVIRDLIVNARLSEGYSDSKGIFSARKA
IMQYCQLKGFPDVDIEDIYLGNGVSELISISLQALLDNGDEVLVPMPDYPLWTACVSLGGGKAVHYLCDEEAGWYPDIAD
IKSKITSRTKAIVVINPNNPTGALYPKEILEDIVALAREHQLIIFADEIYDRLVMDGKEHIAIASLAPDVFCVSMNGLSK
SHRIAGFRVGWMVLSGPKDHVKGYIEGLNMLANMRLCSNVLAQQVVQTSLGGHQSVDALLLPGGRIFEQRNFIYEAINAI
PGLSAVKPEAGLYLFPKIDRQMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKDPDHFRIVYLPSVEELEDVQEKITRVLY
QYRR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=370, Percent_Identity=27.8378378378378, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI19263340, Length=366, Percent_Identity=27.5956284153005, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI215599424, Length=366, Percent_Identity=27.5956284153005, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI4885351, Length=453, Percent_Identity=24.9448123620309, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI95147551, Length=407, Percent_Identity=23.5872235872236, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI169881279, Length=407, Percent_Identity=23.5872235872236, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI169881281, Length=346, Percent_Identity=23.6994219653179, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI56713254, Length=188, Percent_Identity=27.6595744680851, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI56713256, Length=188, Percent_Identity=27.6595744680851, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI1788627, Length=404, Percent_Identity=61.8811881188119, Blast_Score=536, Evalue=1e-154,
Organism=Escherichia coli, GI1788722, Length=379, Percent_Identity=25.8575197889182, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1786816, Length=234, Percent_Identity=23.5042735042735, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787909, Length=310, Percent_Identity=23.5483870967742, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17567663, Length=375, Percent_Identity=28.2666666666667, Blast_Score=159, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI71981209, Length=475, Percent_Identity=25.4736842105263, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI71994476, Length=151, Percent_Identity=35.0993377483444, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71994472, Length=151, Percent_Identity=35.0993377483444, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17567369, Length=246, Percent_Identity=28.4552845528455, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71981215, Length=308, Percent_Identity=25.974025974026, Blast_Score=88, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323118, Length=377, Percent_Identity=27.3209549071618, Blast_Score=126, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6320317, Length=383, Percent_Identity=27.4151436031332, Blast_Score=123, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6322401, Length=238, Percent_Identity=25.2100840336134, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI18859735, Length=354, Percent_Identity=27.1186440677966, Blast_Score=148, Evalue=7e-36,
Organism=Drosophila melanogaster, GI45551451, Length=459, Percent_Identity=26.1437908496732, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24641770, Length=459, Percent_Identity=26.1437908496732, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24641760, Length=459, Percent_Identity=26.1437908496732, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24641768, Length=459, Percent_Identity=26.1437908496732, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24641766, Length=459, Percent_Identity=26.1437908496732, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24641764, Length=459, Percent_Identity=26.1437908496732, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI28573069, Length=273, Percent_Identity=26.007326007326, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24646114, Length=273, Percent_Identity=26.007326007326, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI28573067, Length=273, Percent_Identity=26.007326007326, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI28573065, Length=273, Percent_Identity=26.007326007326, Blast_Score=89, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 45224; Mature: 45224

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIEKSSKLEHVAYDIRGPVLDEANRMIASGEKILRLNTGNPAAFGFEAPDEVIRDLIV
CCCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCCEECCCCHHHHHHHHHH
NARLSEGYSDSKGIFSARKAIMQYCQLKGFPDVDIEDIYLGNGVSELISISLQALLDNGD
HHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCC
EVLVPMPDYPLWTACVSLGGGKAVHYLCDEEAGWYPDIADIKSKITSRTKAIVVINPNNP
EEEEECCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEEECCCC
TGALYPKEILEDIVALAREHQLIIFADEIYDRLVMDGKEHIAIASLAPDVFCVSMNGLSK
CCCCCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCC
SHRIAGFRVGWMVLSGPKDHVKGYIEGLNMLANMRLCSNVLAQQVVQTSLGGHQSVDALL
CCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
LPGGRIFEQRNFIYEAINAIPGLSAVKPEAGLYLFPKIDRQMYRIDDDEEFVLQLLKQEK
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHEECCCCHHHHHHHHHCCC
VMLVHGRGFNWKDPDHFRIVYLPSVEELEDVQEKITRVLYQYRR
EEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKIIEKSSKLEHVAYDIRGPVLDEANRMIASGEKILRLNTGNPAAFGFEAPDEVIRDLIV
CCCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEECCCCCEECCCCHHHHHHHHHH
NARLSEGYSDSKGIFSARKAIMQYCQLKGFPDVDIEDIYLGNGVSELISISLQALLDNGD
HHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCC
EVLVPMPDYPLWTACVSLGGGKAVHYLCDEEAGWYPDIADIKSKITSRTKAIVVINPNNP
EEEEECCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHCCCEEEEEEECCCC
TGALYPKEILEDIVALAREHQLIIFADEIYDRLVMDGKEHIAIASLAPDVFCVSMNGLSK
CCCCCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCC
SHRIAGFRVGWMVLSGPKDHVKGYIEGLNMLANMRLCSNVLAQQVVQTSLGGHQSVDALL
CCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
LPGGRIFEQRNFIYEAINAIPGLSAVKPEAGLYLFPKIDRQMYRIDDDEEFVLQLLKQEK
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHEECCCCHHHHHHHHHCCC
VMLVHGRGFNWKDPDHFRIVYLPSVEELEDVQEKITRVLYQYRR
EEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]