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The map label for this gene is accB [H]

Identifier: 15675596

GI number: 15675596

Start: 1448526

End: 1449026

Strand: Reverse

Name: accB [H]

Synonym: SPy_1747

Alternate gene names: 15675596

Gene position: 1449026-1448526 (Counterclockwise)

Preceding gene: 15675597

Following gene: 15675595

Centisome position: 78.22

GC content: 41.52

Gene sequence:

>501_bases
TTGAATATTCAAGAAATCAAAGATTTGATGGCTCAGTTTGATACCTCAAGCCTACGTGAATTTTTATTCAAAACAAATGA
AGGTGAGCTAATCTTTAGTAAAAACGAACAACACCTCAATGCATCGACATCAAATCAAGAACATGCTGTGCCTGTACCAC
AGGTACAACTTGTTCCGAATCCAACTGCTTCGGAAGCGTCCAGTCCAGCATCAGTTAAGGATGTTCCTGTAGAGGAGCAA
CCACAAGCAGAATCTTTTGTAGCAGAAGGTGATATTGTTGAAAGTCCTTTAGTCGGTGTAGCCTATCTTGCAGCTAGCCC
TGACAAGCCACCATTTGTGGCAGTCGGAGATACTGTAAAAAAAGGACAAACCCTTGTGATTATCGAAGCCATGAAGGTGA
TGAACGAAGTGCCAGCGCCATGTGATGGTGTGATTACAGAAATTTTGGTATCAAATGAAGATGTCATTGAATTTGGACAA
GGATTGGTGCGGATCAAATGA

Upstream 100 bases:

>100_bases
GGAGAAGGAAAAGAAACAGCTATCAACTATGCCATTTCAAATACTTTTGGATTTGGTGGTCATAATGCTGTATTAGCTTT
CAAATGTTGGGAGGAGTAGG

Downstream 100 bases:

>100_bases
TGGATATTAGAGAAATTCAAGCGGCTTTGCCTCATCGCTACCCAATGTTATTGGTTGATCGTGTGTTAGAAGTGTCAGAC
GACCATATCGTTGCCATTAA

Product: acetyl-CoA carboxylase biotin carboxyl carrier protein subunit

Products: Malonyl-CoA; malonyl-CoA; phosphate; ADP [C]

Alternate protein names: BCCP [H]

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MNIQEIKDLMAQFDTSSLREFLFKTNEGELIFSKNEQHLNASTSNQEHAVPVPQVQLVPNPTASEASSPASVKDVPVEEQ
PQAESFVAEGDIVESPLVGVAYLAASPDKPPFVAVGDTVKKGQTLVIIEAMKVMNEVPAPCDGVITEILVSNEDVIEFGQ
GLVRIK

Sequences:

>Translated_166_residues
MNIQEIKDLMAQFDTSSLREFLFKTNEGELIFSKNEQHLNASTSNQEHAVPVPQVQLVPNPTASEASSPASVKDVPVEEQ
PQAESFVAEGDIVESPLVGVAYLAASPDKPPFVAVGDTVKKGQTLVIIEAMKVMNEVPAPCDGVITEILVSNEDVIEFGQ
GLVRIK
>Mature_166_residues
MNIQEIKDLMAQFDTSSLREFLFKTNEGELIFSKNEQHLNASTSNQEHAVPVPQVQLVPNPTASEASSPASVKDVPVEEQ
PQAESFVAEGDIVESPLVGVAYLAASPDKPPFVAVGDTVKKGQTLVIIEAMKVMNEVPAPCDGVITEILVSNEDVIEFGQ
GLVRIK

Specific function: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA [H]

COG id: COG0511

COG function: function code I; Biotin carboxyl carrier protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789653, Length=166, Percent_Identity=34.9397590361446, Blast_Score=82, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001249
- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl [H]

EC number: NA

Molecular weight: Translated: 17901; Mature: 17901

Theoretical pI: Translated: 4.09; Mature: 4.09

Prosite motif: PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIQEIKDLMAQFDTSSLREFLFKTNEGELIFSKNEQHLNASTSNQEHAVPVPQVQLVPN
CCHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEECCC
PTASEASSPASVKDVPVEEQPQAESFVAEGDIVESPLVGVAYLAASPDKPPFVAVGDTVK
CCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHEEEEECCCCCCCEEEECCCCC
KGQTLVIIEAMKVMNEVPAPCDGVITEILVSNEDVIEFGQGLVRIK
CCCEEEEHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHCCCEEECC
>Mature Secondary Structure
MNIQEIKDLMAQFDTSSLREFLFKTNEGELIFSKNEQHLNASTSNQEHAVPVPQVQLVPN
CCHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCEEECCC
PTASEASSPASVKDVPVEEQPQAESFVAEGDIVESPLVGVAYLAASPDKPPFVAVGDTVK
CCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCHHEEEEECCCCCCCEEEECCCCC
KGQTLVIIEAMKVMNEVPAPCDGVITEILVSNEDVIEFGQGLVRIK
CCCEEEEHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; HCO3-; Proton; acetyl-CoA; ATP [C]

Specific reaction: acetyl-CoA = malonyl-CoA HCO3- + Proton + acetyl-CoA + ATP = malonyl-CoA + phosphate + ADP [C]

General reaction: Ligases; Forming Carbon-Carbon Bonds; acetyl-CoA carboxylase Reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA