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The map label for this gene is atoA [H]

Identifier: 15675512

GI number: 15675512

Start: 1358906

End: 1359565

Strand: Direct

Name: atoA [H]

Synonym: SPy_1639

Alternate gene names: 15675512

Gene position: 1358906-1359565 (Clockwise)

Preceding gene: 15675511

Following gene: 15675513

Centisome position: 73.36

GC content: 41.36

Gene sequence:

>660_bases
ATGGGAACATCAACTACTGTTCTTTCAAAAGAAGAGATTCAAACACGTATTGCTAAGCGCGTTGCACAAGAATTAGAACA
CAATACACTGGTCAACTTAGGCATAGGTTTGCCAACAAAAGTAGCCAACTATATTCCTGAAGGTGTAACCATTACCCTGC
AGTCCGAAAATGGTTTTGTCGGTCTCACTGGATTAACAGATGATCACTACGATCCTACTATTGTTAATGCTGGTGGGCAA
CCTGTTAGTATTGCTCCTGGAGGGGCTTTCTTCGATAGCTCAACTTCCTTTGGTATTATTCGAGGCGGCCATGTGGCCGC
AACCGTCTTAGGTGCCTTACAAGTTGATAAAGAAGCTAGCATTGCTAATTACCTGATTCCTGGAAAAATGGTTCCTGGGA
TGGGAGGGGCCATGGACTTATTGGTAGGTGCTAAAAAAGTCATTGTTGCAATGGAGCATACCAATAAAGGCAAAGCAAAA
ATTTTAGACAAATGCACCCTTCCTCTGACTGCTCAAAATGTTGTTAACCTAATCATTACTGAAATGGGAGTCTTTGAATA
TCAAGATGAAGGTCTATGCGCCCTTGAAATTAACCCAGATTACACCTTTGAAGACGTGCAAAACGTTACCGAAGTTACCC
TAATTGATAAAACAAACTAA

Upstream 100 bases:

>100_bases
ATTGTTGAAGCAAGAGAAATTGTTGACGTGGGGCAAATGGATCCTAATTTTGTCCATACTCCTGGCATTTTTGTTAACTA
CTTAGTGAAAGGAGCCTAAC

Downstream 100 bases:

>100_bases
AGACTAACCAAAAGAAAGACGAGGATAGTATCATGACACATACTAAAGAAGTTGCATTTATCACTGGTGCTGCAAGCGGA
ATTGGAAAACAAATCGGGGA

Product: putative Acetyl-CoA:acetoacetyl-CoA transferase b subunit

Products: NA

Alternate protein names: Acetyl-CoA:acetoacetate-CoA transferase subunit beta [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MGTSTTVLSKEEIQTRIAKRVAQELEHNTLVNLGIGLPTKVANYIPEGVTITLQSENGFVGLTGLTDDHYDPTIVNAGGQ
PVSIAPGGAFFDSSTSFGIIRGGHVAATVLGALQVDKEASIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKAK
ILDKCTLPLTAQNVVNLIITEMGVFEYQDEGLCALEINPDYTFEDVQNVTEVTLIDKTN

Sequences:

>Translated_219_residues
MGTSTTVLSKEEIQTRIAKRVAQELEHNTLVNLGIGLPTKVANYIPEGVTITLQSENGFVGLTGLTDDHYDPTIVNAGGQ
PVSIAPGGAFFDSSTSFGIIRGGHVAATVLGALQVDKEASIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKAK
ILDKCTLPLTAQNVVNLIITEMGVFEYQDEGLCALEINPDYTFEDVQNVTEVTLIDKTN
>Mature_218_residues
GTSTTVLSKEEIQTRIAKRVAQELEHNTLVNLGIGLPTKVANYIPEGVTITLQSENGFVGLTGLTDDHYDPTIVNAGGQP
VSIAPGGAFFDSSTSFGIIRGGHVAATVLGALQVDKEASIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKAKI
LDKCTLPLTAQNVVNLIITEMGVFEYQDEGLCALEINPDYTFEDVQNVTEVTLIDKTN

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG2057

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit B family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=213, Percent_Identity=48.8262910798122, Blast_Score=194, Evalue=5e-50,
Organism=Homo sapiens, GI11545841, Length=206, Percent_Identity=45.1456310679612, Blast_Score=178, Evalue=3e-45,
Organism=Escherichia coli, GI1788552, Length=204, Percent_Identity=57.3529411764706, Blast_Score=241, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI17531517, Length=198, Percent_Identity=45.4545454545455, Blast_Score=167, Evalue=3e-42,
Organism=Drosophila melanogaster, GI24655794, Length=198, Percent_Identity=47.4747474747475, Blast_Score=187, Evalue=4e-48,
Organism=Drosophila melanogaster, GI21358325, Length=198, Percent_Identity=47.4747474747475, Blast_Score=187, Evalue=4e-48,

Paralogues:

None

Copy number: 369 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012791
- InterPro:   IPR004165
- InterPro:   IPR004164 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.8 [H]

Molecular weight: Translated: 23217; Mature: 23086

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS01274 COA_TRANSF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTSTTVLSKEEIQTRIAKRVAQELEHNTLVNLGIGLPTKVANYIPEGVTITLQSENGFV
CCCCCCEECHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCEEEEEECCCCEE
GLTGLTDDHYDPTIVNAGGQPVSIAPGGAFFDSSTSFGIIRGGHVAATVLGALQVDKEAS
EEECCCCCCCCCEEECCCCCEEEECCCCCEECCCCCEEEEECCHHHHHHHHHHHCCCCCC
IANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKAKILDKCTLPLTAQNVVNLIIT
HHHEECCCCCCCCCCCHHHHHHCCEEEEEEEECCCCCCCEEHHHCCCCCCHHHHHHHHHH
EMGVFEYQDEGLCALEINPDYTFEDVQNVTEVTLIDKTN
HCCCEEECCCCEEEEEECCCCCHHHHCCCEEEEEEECCC
>Mature Secondary Structure 
GTSTTVLSKEEIQTRIAKRVAQELEHNTLVNLGIGLPTKVANYIPEGVTITLQSENGFV
CCCCCEECHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCEEEEEECCCCEE
GLTGLTDDHYDPTIVNAGGQPVSIAPGGAFFDSSTSFGIIRGGHVAATVLGALQVDKEAS
EEECCCCCCCCCEEECCCCCEEEECCCCCEECCCCCEEEEECCHHHHHHHHHHHCCCCCC
IANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKAKILDKCTLPLTAQNVVNLIIT
HHHEECCCCCCCCCCCHHHHHHCCEEEEEEEECCCCCCCEEHHHCCCCCCHHHHHHHHHH
EMGVFEYQDEGLCALEINPDYTFEDVQNVTEVTLIDKTN
HCCCEEECCCCEEEEEECCCCCHHHHCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]