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The map label for this gene is atoB [H]

Identifier: 15675510

GI number: 15675510

Start: 1357043

End: 1358230

Strand: Direct

Name: atoB [H]

Synonym: SPy_1637

Alternate gene names: 15675510

Gene position: 1357043-1358230 (Clockwise)

Preceding gene: 15675496

Following gene: 15675511

Centisome position: 73.26

GC content: 41.08

Gene sequence:

>1188_bases
ATGAAAAACATAGTTATCGTTGAAGCTTTACGAACTCCTATCGGAGCTTTTGGAGGCTCCTTTAAAAGTGTCTCTGCTGT
TGAACTTGGAACAACTGTACTGAAAAAAATCCTTGATAAAACGCAAGTAAAGCCTGAAATGGTTGATGAAGTCATCCTAG
GAAACGTCCTTCATGCAGGCCTAGGACAAAATGTGGCAAGACAAGTTGCAGTCCACTCAGGAATTCCTGAAGATAAAACA
GCTTTCACATTAGATATGGTTTGCGGTTCTGGACTTAAAGCAATCCAATTAGCTGCGCAAAGCATCATGCTTGGTGACGC
TGATATCGTTATTGCTGGTGGTGTCGAAAACATGTCACAAGCAACCTATGTATCAACTCAGCACCGTTTTGGACAGCGAC
TTGGTAATAGTCAATTGATTGATACTCTTGTTCATGATGGCTTAACAGATGCTTTTAACAATTACCACATGGGTATTACT
GCTGAAAACGTTGCTCAGAAATATGGCATCTCAAGAGAAGAGCAAGATCAATTTGCTTTAGAAAGCCAAGAAAAAGCTGC
TAAAGCATTAGAAAATCATCGTTTTGCTGACGAAATTGTCCCTGTCTCTGTGCCTCAACGACGCAAAGACCCTTTAATTG
TTACAACAGATGAATACCCAAAAGTTGATACAAGCCTTGAAAAATTACAGCAATTACGTCCTGCTTTCCTCCCTAAAGAA
GGAACCGTTACTGCTGGGAATGCCTCAGGAATAAACGATGGTGCAGCCTTATTGATGTTAATGACTGAAGAAAAAGCTCT
TGAATTAGGGTTAACACCTTTAGTCACTATTGAAAGCTATGCTAGTGCAGGTGTTGCACCTGAACTGATGGGAACTGGAC
CAATTCCTGCCACTCAAAAAGCCCTTAAGAAAGCTGGATTAACAATTTCTGATTTGGACTTAGTGGAGTCCAATGAAGCA
TTTGCAGCACAGTCCTTGGCGGTTTTAAAAGATTTAAAGTTAAACCCAGAAATCGTGAATGTTAATGGAGGAGCCATCGC
TTTAGGTCATCCTATTGGTGCCAGTGGCGCTCGCATTCTAGTCACATTAATCCACGAAATGAAAAAACGCCAAGTAACCA
GAGGACTAGCAACACTTTGCATTGGTGGAGGACAAGGAACTGCTGTTATCGTGAAAAACAATACTTAG

Upstream 100 bases:

>100_bases
TTATATGCTTATAAAAATTCTATATTTTTATTTTTAGCGTTTTCTTGTTATCTTAGAGACATGGAAAGCGCTTTTCTAAA
ACTGAAAGGATGTTTATTTT

Downstream 100 bases:

>100_bases
TCTCGTGAAAGTTGGTAGAAAAAATGTGTAAAGAAATCACAATAAAAGAAGCGGTAGCTCACGTTAAAGATGGTGATACC
ATTATGGTTGGTGGCTTCAT

Product: putative acetyl-CoA:acetyltransferase

Products: NA

Alternate protein names: Acetoacetyl-CoA thiolase [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MKNIVIVEALRTPIGAFGGSFKSVSAVELGTTVLKKILDKTQVKPEMVDEVILGNVLHAGLGQNVARQVAVHSGIPEDKT
AFTLDMVCGSGLKAIQLAAQSIMLGDADIVIAGGVENMSQATYVSTQHRFGQRLGNSQLIDTLVHDGLTDAFNNYHMGIT
AENVAQKYGISREEQDQFALESQEKAAKALENHRFADEIVPVSVPQRRKDPLIVTTDEYPKVDTSLEKLQQLRPAFLPKE
GTVTAGNASGINDGAALLMLMTEEKALELGLTPLVTIESYASAGVAPELMGTGPIPATQKALKKAGLTISDLDLVESNEA
FAAQSLAVLKDLKLNPEIVNVNGGAIALGHPIGASGARILVTLIHEMKKRQVTRGLATLCIGGGQGTAVIVKNNT

Sequences:

>Translated_395_residues
MKNIVIVEALRTPIGAFGGSFKSVSAVELGTTVLKKILDKTQVKPEMVDEVILGNVLHAGLGQNVARQVAVHSGIPEDKT
AFTLDMVCGSGLKAIQLAAQSIMLGDADIVIAGGVENMSQATYVSTQHRFGQRLGNSQLIDTLVHDGLTDAFNNYHMGIT
AENVAQKYGISREEQDQFALESQEKAAKALENHRFADEIVPVSVPQRRKDPLIVTTDEYPKVDTSLEKLQQLRPAFLPKE
GTVTAGNASGINDGAALLMLMTEEKALELGLTPLVTIESYASAGVAPELMGTGPIPATQKALKKAGLTISDLDLVESNEA
FAAQSLAVLKDLKLNPEIVNVNGGAIALGHPIGASGARILVTLIHEMKKRQVTRGLATLCIGGGQGTAVIVKNNT
>Mature_395_residues
MKNIVIVEALRTPIGAFGGSFKSVSAVELGTTVLKKILDKTQVKPEMVDEVILGNVLHAGLGQNVARQVAVHSGIPEDKT
AFTLDMVCGSGLKAIQLAAQSIMLGDADIVIAGGVENMSQATYVSTQHRFGQRLGNSQLIDTLVHDGLTDAFNNYHMGIT
AENVAQKYGISREEQDQFALESQEKAAKALENHRFADEIVPVSVPQRRKDPLIVTTDEYPKVDTSLEKLQQLRPAFLPKE
GTVTAGNASGINDGAALLMLMTEEKALELGLTPLVTIESYASAGVAPELMGTGPIPATQKALKKAGLTISDLDLVESNEA
FAAQSLAVLKDLKLNPEIVNVNGGAIALGHPIGASGARILVTLIHEMKKRQVTRGLATLCIGGGQGTAVIVKNNT

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiolase family [H]

Homologues:

Organism=Homo sapiens, GI148539872, Length=390, Percent_Identity=52.5641025641026, Blast_Score=400, Evalue=1e-112,
Organism=Homo sapiens, GI167614485, Length=394, Percent_Identity=44.1624365482233, Blast_Score=331, Evalue=5e-91,
Organism=Homo sapiens, GI4557237, Length=393, Percent_Identity=43.0025445292621, Blast_Score=310, Evalue=2e-84,
Organism=Homo sapiens, GI4501853, Length=396, Percent_Identity=41.9191919191919, Blast_Score=277, Evalue=1e-74,
Organism=Homo sapiens, GI4504327, Length=432, Percent_Identity=34.2592592592593, Blast_Score=212, Evalue=6e-55,
Organism=Homo sapiens, GI194353979, Length=396, Percent_Identity=31.3131313131313, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI19923233, Length=404, Percent_Identity=25.990099009901, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI87082165, Length=394, Percent_Identity=57.8680203045685, Blast_Score=451, Evalue=1e-128,
Organism=Escherichia coli, GI1788554, Length=393, Percent_Identity=59.7964376590331, Blast_Score=446, Evalue=1e-126,
Organism=Escherichia coli, GI1787663, Length=404, Percent_Identity=43.5643564356436, Blast_Score=311, Evalue=4e-86,
Organism=Escherichia coli, GI48994986, Length=405, Percent_Identity=41.4814814814815, Blast_Score=279, Evalue=3e-76,
Organism=Escherichia coli, GI1788683, Length=412, Percent_Identity=33.252427184466, Blast_Score=216, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI133906874, Length=392, Percent_Identity=42.8571428571429, Blast_Score=318, Evalue=3e-87,
Organism=Caenorhabditis elegans, GI17535921, Length=393, Percent_Identity=42.4936386768448, Blast_Score=302, Evalue=2e-82,
Organism=Caenorhabditis elegans, GI25147385, Length=395, Percent_Identity=41.0126582278481, Blast_Score=291, Evalue=4e-79,
Organism=Caenorhabditis elegans, GI17551802, Length=428, Percent_Identity=31.5420560747664, Blast_Score=202, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17535917, Length=393, Percent_Identity=32.3155216284987, Blast_Score=181, Evalue=4e-46,
Organism=Saccharomyces cerevisiae, GI6325229, Length=398, Percent_Identity=44.4723618090452, Blast_Score=311, Evalue=2e-85,
Organism=Saccharomyces cerevisiae, GI6322031, Length=401, Percent_Identity=38.1546134663342, Blast_Score=242, Evalue=6e-65,
Organism=Drosophila melanogaster, GI24655093, Length=392, Percent_Identity=48.9795918367347, Blast_Score=377, Evalue=1e-105,
Organism=Drosophila melanogaster, GI17648125, Length=393, Percent_Identity=44.529262086514, Blast_Score=322, Evalue=2e-88,
Organism=Drosophila melanogaster, GI24640423, Length=390, Percent_Identity=42.8205128205128, Blast_Score=316, Evalue=1e-86,
Organism=Drosophila melanogaster, GI17137578, Length=432, Percent_Identity=33.3333333333333, Blast_Score=194, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020615
- InterPro:   IPR020617
- InterPro:   IPR020613
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: =2.3.1.9 [H]

Molecular weight: Translated: 41801; Mature: 41801

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS00737 THIOLASE_2 ; PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIVIVEALRTPIGAFGGSFKSVSAVELGTTVLKKILDKTQVKPEMVDEVILGNVLHAG
CCCEEEEHHHHCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LGQNVARQVAVHSGIPEDKTAFTLDMVCGSGLKAIQLAAQSIMLGDADIVIAGGVENMSQ
CCHHHHHHHHHHCCCCCCCCEEEEEHHHCCCHHHHHHHHHHHEECCCCEEEECCCCCCHH
ATYVSTQHRFGQRLGNSQLIDTLVHDGLTDAFNNYHMGITAENVAQKYGISREEQDQFAL
HHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHCCCCCCEEHHHHHHHHCCCCCHHHHHHH
ESQEKAAKALENHRFADEIVPVSVPQRRKDPLIVTTDEYPKVDTSLEKLQQLRPAFLPKE
HHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCC
GTVTAGNASGINDGAALLMLMTEEKALELGLTPLVTIESYASAGVAPELMGTGPIPATQK
CCEECCCCCCCCCCEEEEEEEECHHHHHHCCCCEEEEHHHHCCCCCHHHCCCCCCCHHHH
ALKKAGLTISDLDLVESNEAFAAQSLAVLKDLKLNPEIVNVNGGAIALGHPIGASGARIL
HHHHHCCEEEHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCEEEECCCCCCCHHHHH
VTLIHEMKKRQVTRGLATLCIGGGQGTAVIVKNNT
HHHHHHHHHHHHHHHHHHEEEECCCCEEEEEECCC
>Mature Secondary Structure
MKNIVIVEALRTPIGAFGGSFKSVSAVELGTTVLKKILDKTQVKPEMVDEVILGNVLHAG
CCCEEEEHHHHCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LGQNVARQVAVHSGIPEDKTAFTLDMVCGSGLKAIQLAAQSIMLGDADIVIAGGVENMSQ
CCHHHHHHHHHHCCCCCCCCEEEEEHHHCCCHHHHHHHHHHHEECCCCEEEECCCCCCHH
ATYVSTQHRFGQRLGNSQLIDTLVHDGLTDAFNNYHMGITAENVAQKYGISREEQDQFAL
HHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHCCCCCCEEHHHHHHHHCCCCCHHHHHHH
ESQEKAAKALENHRFADEIVPVSVPQRRKDPLIVTTDEYPKVDTSLEKLQQLRPAFLPKE
HHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCC
GTVTAGNASGINDGAALLMLMTEEKALELGLTPLVTIESYASAGVAPELMGTGPIPATQK
CCEECCCCCCCCCCEEEEEEEECHHHHHHCCCCEEEEHHHHCCCCCHHHCCCCCCCHHHH
ALKKAGLTISDLDLVESNEAFAAQSLAVLKDLKLNPEIVNVNGGAIALGHPIGASGARIL
HHHHHCCEEEHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCEEEECCCCCCCHHHHH
VTLIHEMKKRQVTRGLATLCIGGGQGTAVIVKNNT
HHHHHHHHHHHHHHHHHHEEEECCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA