Click here to switch to the map view.

The map label for this gene is inlA [H]

Identifier: 15675293

GI number: 15675293

Start: 1127063

End: 1129441

Strand: Reverse

Name: inlA [H]

Synonym: SPy_1361

Alternate gene names: 15675293

Gene position: 1129441-1127063 (Counterclockwise)

Preceding gene: 15675295

Following gene: 15675292

Centisome position: 60.97

GC content: 38.46

Gene sequence:

>2379_bases
ATGAAAACGAAAAAAGTTATTATTTTAGTTGGTCTATTGTTATCATCTCAGTTGACTTTGATAGCTTGTCAATCACGAGG
TAATGGTACATATCCCATTAAAACGAAACAATCACGTAAGGGAATGACGTCAAACAAAATTAAACCGATTAAAAAAAGCA
AAAAGACAAACAAGACTCACAAAGGTGTGGCGGGTGTCGATTTTCCTACAGATGATGGGTTTATTTTAACCAAAGACTCA
AAAATCTTATCAAAAACAGATCAGGGAATCGTTGTTGACCATGATGGTCATTCGCATTTTATTTTTTATGCCGATTTAAA
GGGAAGTCCATTTGAATACCTTATTCCAAAAGGAGCAAGTTTAGCTAAGCCAGCTGTTGCTCAGCGAGCAGCTAGTCAAG
GGACTTCTAAAGTAGCAGATCCTCATCACCATTATGAATTTAACCCAGCGGATATTGTGGCTGAAGATGCTTTAGGCTAC
ACGGTTCGCCACGATGATCACTTCCATTATATTTTGAAGTCAAGCTTATCAGGTCAGACACAGGCACAAGCTAAACAGGT
TGCTACTCGCTTGCCACAAACCAGTAGCCTTGTTTCAACAGCTACAGCTAATGGTATTCCAGGCTTGCATTTCCCAACCT
CAGATGGTTTTCAATTTAACGGTCAAGGTATTGTTGGGGTAACAAAAGACAGTATTTTAGTGGACCACGATGGTCACTTA
CATCCTATTTCTTTTGCGGACCTTCGTCAGGGTGGCTGGGCACATGTGGCAGATCAATACGATCCCGCTAAAAAAGCAGA
AAAGCCAGCAGAAACCCATCAGACACCAGAGCTATCTGAACGTGAAAAGGAATACCAAGAAAAATTAGCTTATTTGGCAG
AAAAATTGGGGATTGATCCATCAACTATTAAACGTGTGGAAACACAAGACGGTAAACTTGGTTTGGAATACCCTCACCAT
GACCACGCACACGTATTGATGTTATCTGATATTGAAATCGGAAAAGACATTCCAGATCCACATGCTATTGAGCATGCCCG
TGAATTGGAAAAACATAAGGTTGGAATGGATACCTTGCGTGCCTTAGGGTTTGATGAAGAAGTGATTTTGGATATCGTTC
GCACTCACGATGCTCCAACCCCATTCCCATCAAATGAAAAAGATCCGAATATGATGAAAGAATGGTTAGCAACGGTTATC
AAACTTGACTTGGGCAGCCGTAAAGATCCTTTGCAACGTAAAGGACTTTCACTGTTACCCAACTTAGAAACTTTAGGAAT
TGGCTTTACACCAATCAAAGATATCTCACCTGTTTTGCAATTTAAAAAATTGAAACAGTTGTTAATGACAAAAACAGGGG
TGACTGATTATAGATTTTTGGATAATATGCCACAGTTAGAAGGCATTGATATTTCACAAAACAATCTCAAAGATATTAGT
TTCTTGAGCAAATATAAAAACTTAACTCTAGTAGCGGCTGCTGATAATGGTATTGAAGATATTAGGCCGCTTGGTCAATT
ACCAAATCTCAAATTCCTCGTATTGAGTAACAATAAGATTTCTGATTTAAGCCCACTGGCATCGTTACATCAATTGCAAG
AATTGCACATTGATAATAATCAGATTACAGATTTAAGCCCTGTTTCTCATAAAGAATCATTGACGGTTGTTGATTTATCA
AGAAATGCTGATGTTGACTTAGCAACACTTCAAGCACCCAAATTAGAAACGTTAATGGTCAATGATACCAAGGTTTCTCA
TTTGGATTTCTTGAAAAATAATCCTAATCTATCTAGCCTATCTATTAACCGTGCGCAATTGCAATCTCTTGAAGGTATTG
AAGCAAGTAGCGTCATTGTCAGAGTAGAAGCAGAAGGTAACCAAATTAAATCGCTTGTGCTTAAAGACAAGCAAGGGTCA
CTTACTTTCTTGGATGTGACAGGCAACCAGTTGACTTCTCTAGAAGGTGTTAATAATTTTACAGCACTTGACATTTTAAG
CGTGTCTAAAAACCAATTAACAAATGTCAACCTATCTAAACCCAATAAGACAGTTACTAACATTGATATTAGTCATAACA
ATATCTCATTAGCAGACCTTAAATTGAACGAGCAACATATTCCAGAAGCCATTGCGAAAAACTTCCCAGCGGTTTACGAA
GGTTCTATGGTAGGTAATGGAACAGCTGAAGAAAAAGCAGCTATGGCTACTAAGGCGAAAGAAAGTGCTCAAGAAGCATC
GGAATCACATGACTACAACCATAATCATACCTATGAAGATGAAGAAGGTCATGCTCACGAGCACAGAGACAAAGATGATC
ACGACCATGAACATGAGGATGAAAATGAAGCTAAAGATGAGCAAAACCATGCTGACTAA

Upstream 100 bases:

>100_bases
GAGCTCCAACTCGTCAACAACTAATAGTTATCCTAAAAAGAGCTTGAGGAAAAACAAGTGATGTGATATACTTAACCAGT
TAAATAAAAAGGAGGGTTGA

Downstream 100 bases:

>100_bases
ACTAATCTAAGAATAACCCGATCCAACTGAATCGTCCTAATGACACCATTGTTGACTATCAAGAGAACCTCAAGAATAAC
CTTGAGGTTTTTTTGAAATA

Product: putative internalin A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 792; Mature: 792

Protein sequence:

>792_residues
MKTKKVIILVGLLLSSQLTLIACQSRGNGTYPIKTKQSRKGMTSNKIKPIKKSKKTNKTHKGVAGVDFPTDDGFILTKDS
KILSKTDQGIVVDHDGHSHFIFYADLKGSPFEYLIPKGASLAKPAVAQRAASQGTSKVADPHHHYEFNPADIVAEDALGY
TVRHDDHFHYILKSSLSGQTQAQAKQVATRLPQTSSLVSTATANGIPGLHFPTSDGFQFNGQGIVGVTKDSILVDHDGHL
HPISFADLRQGGWAHVADQYDPAKKAEKPAETHQTPELSEREKEYQEKLAYLAEKLGIDPSTIKRVETQDGKLGLEYPHH
DHAHVLMLSDIEIGKDIPDPHAIEHARELEKHKVGMDTLRALGFDEEVILDIVRTHDAPTPFPSNEKDPNMMKEWLATVI
KLDLGSRKDPLQRKGLSLLPNLETLGIGFTPIKDISPVLQFKKLKQLLMTKTGVTDYRFLDNMPQLEGIDISQNNLKDIS
FLSKYKNLTLVAAADNGIEDIRPLGQLPNLKFLVLSNNKISDLSPLASLHQLQELHIDNNQITDLSPVSHKESLTVVDLS
RNADVDLATLQAPKLETLMVNDTKVSHLDFLKNNPNLSSLSINRAQLQSLEGIEASSVIVRVEAEGNQIKSLVLKDKQGS
LTFLDVTGNQLTSLEGVNNFTALDILSVSKNQLTNVNLSKPNKTVTNIDISHNNISLADLKLNEQHIPEAIAKNFPAVYE
GSMVGNGTAEEKAAMATKAKESAQEASESHDYNHNHTYEDEEGHAHEHRDKDDHDHEHEDENEAKDEQNHAD

Sequences:

>Translated_792_residues
MKTKKVIILVGLLLSSQLTLIACQSRGNGTYPIKTKQSRKGMTSNKIKPIKKSKKTNKTHKGVAGVDFPTDDGFILTKDS
KILSKTDQGIVVDHDGHSHFIFYADLKGSPFEYLIPKGASLAKPAVAQRAASQGTSKVADPHHHYEFNPADIVAEDALGY
TVRHDDHFHYILKSSLSGQTQAQAKQVATRLPQTSSLVSTATANGIPGLHFPTSDGFQFNGQGIVGVTKDSILVDHDGHL
HPISFADLRQGGWAHVADQYDPAKKAEKPAETHQTPELSEREKEYQEKLAYLAEKLGIDPSTIKRVETQDGKLGLEYPHH
DHAHVLMLSDIEIGKDIPDPHAIEHARELEKHKVGMDTLRALGFDEEVILDIVRTHDAPTPFPSNEKDPNMMKEWLATVI
KLDLGSRKDPLQRKGLSLLPNLETLGIGFTPIKDISPVLQFKKLKQLLMTKTGVTDYRFLDNMPQLEGIDISQNNLKDIS
FLSKYKNLTLVAAADNGIEDIRPLGQLPNLKFLVLSNNKISDLSPLASLHQLQELHIDNNQITDLSPVSHKESLTVVDLS
RNADVDLATLQAPKLETLMVNDTKVSHLDFLKNNPNLSSLSINRAQLQSLEGIEASSVIVRVEAEGNQIKSLVLKDKQGS
LTFLDVTGNQLTSLEGVNNFTALDILSVSKNQLTNVNLSKPNKTVTNIDISHNNISLADLKLNEQHIPEAIAKNFPAVYE
GSMVGNGTAEEKAAMATKAKESAQEASESHDYNHNHTYEDEEGHAHEHRDKDDHDHEHEDENEAKDEQNHAD
>Mature_792_residues
MKTKKVIILVGLLLSSQLTLIACQSRGNGTYPIKTKQSRKGMTSNKIKPIKKSKKTNKTHKGVAGVDFPTDDGFILTKDS
KILSKTDQGIVVDHDGHSHFIFYADLKGSPFEYLIPKGASLAKPAVAQRAASQGTSKVADPHHHYEFNPADIVAEDALGY
TVRHDDHFHYILKSSLSGQTQAQAKQVATRLPQTSSLVSTATANGIPGLHFPTSDGFQFNGQGIVGVTKDSILVDHDGHL
HPISFADLRQGGWAHVADQYDPAKKAEKPAETHQTPELSEREKEYQEKLAYLAEKLGIDPSTIKRVETQDGKLGLEYPHH
DHAHVLMLSDIEIGKDIPDPHAIEHARELEKHKVGMDTLRALGFDEEVILDIVRTHDAPTPFPSNEKDPNMMKEWLATVI
KLDLGSRKDPLQRKGLSLLPNLETLGIGFTPIKDISPVLQFKKLKQLLMTKTGVTDYRFLDNMPQLEGIDISQNNLKDIS
FLSKYKNLTLVAAADNGIEDIRPLGQLPNLKFLVLSNNKISDLSPLASLHQLQELHIDNNQITDLSPVSHKESLTVVDLS
RNADVDLATLQAPKLETLMVNDTKVSHLDFLKNNPNLSSLSINRAQLQSLEGIEASSVIVRVEAEGNQIKSLVLKDKQGS
LTFLDVTGNQLTSLEGVNNFTALDILSVSKNQLTNVNLSKPNKTVTNIDISHNNISLADLKLNEQHIPEAIAKNFPAVYE
GSMVGNGTAEEKAAMATKAKESAQEASESHDYNHNHTYEDEEGHAHEHRDKDDHDHEHEDENEAKDEQNHAD

Specific function: Mediates the entry of Listeria monocytogenes into cells [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 14 LRR (leucine-rich) repeats [H]

Homologues:

Organism=Homo sapiens, GI4506013, Length=234, Percent_Identity=25.2136752136752, Blast_Score=69, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014755
- InterPro:   IPR019948
- InterPro:   IPR014756
- InterPro:   IPR001611
- InterPro:   IPR013378
- InterPro:   IPR019931
- InterPro:   IPR012569
- InterPro:   IPR001899 [H]

Pfam domain/function: PF09479 Flg_new; PF00746 Gram_pos_anchor; PF00560 LRR_1; PF08191 LRR_adjacent [H]

EC number: NA

Molecular weight: Translated: 87459; Mature: 87459

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKKVIILVGLLLSSQLTLIACQSRGNGTYPIKTKQSRKGMTSNKIKPIKKSKKTNKTH
CCCCEEEEEEEHHHCCCEEEEEEECCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHCCCHH
KGVAGVDFPTDDGFILTKDSKILSKTDQGIVVDHDGHSHFIFYADLKGSPFEYLIPKGAS
CCCCCCCCCCCCCEEEECCCHHHHCCCCCEEEECCCCEEEEEEEECCCCCCEEECCCCCC
LAKPAVAQRAASQGTSKVADPHHHYEFNPADIVAEDALGYTVRHDDHFHYILKSSLSGQT
CCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEECCCCEEEEEHHCCCCCH
QAQAKQVATRLPQTSSLVSTATANGIPGLHFPTSDGFQFNGQGIVGVTKDSILVDHDGHL
HHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCEECCCEEEEECCCCEEEECCCCC
HPISFADLRQGGWAHVADQYDPAKKAEKPAETHQTPELSEREKEYQEKLAYLAEKLGIDP
CCCCHHHHCCCCCEECCCCCCCHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCH
STIKRVETQDGKLGLEYPHHDHAHVLMLSDIEIGKDIPDPHAIEHARELEKHKVGMDTLR
HHHHHHCCCCCCEECCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHHHH
ALGFDEEVILDIVRTHDAPTPFPSNEKDPNMMKEWLATVIKLDLGSRKDPLQRKGLSLLP
HCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCC
NLETLGIGFTPIKDISPVLQFKKLKQLLMTKTGVTDYRFLDNMPQLEGIDISQNNLKDIS
CCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCHHHH
FLSKYKNLTLVAAADNGIEDIRPLGQLPNLKFLVLSNNKISDLSPLASLHQLQELHIDNN
HHHHHCCEEEEEECCCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCC
QITDLSPVSHKESLTVVDLSRNADVDLATLQAPKLETLMVNDTKVSHLDFLKNNPNLSSL
CCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCEEEEECCCCCHHHHHHCCCCCCCEE
SINRAQLQSLEGIEASSVIVRVEAEGNQIKSLVLKDKQGSLTFLDVTGNQLTSLEGVNNF
ECCHHHHHHHCCCCCCEEEEEEECCCCCEEEEEEECCCCCEEEEEECCCCEEECCCCCCC
TALDILSVSKNQLTNVNLSKPNKTVTNIDISHNNISLADLKLNEQHIPEAIAKNFPAVYE
EEEEEEECCCCCCCEEECCCCCCEEEEEEECCCCEEEEEEECCHHHHHHHHHCCCCCEEC
GSMVGNGTAEEKAAMATKAKESAQEASESHDYNHNHTYEDEEGHAHEHRDKDDHDHEHED
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCC
ENEAKDEQNHAD
HHHHHHHHCCCC
>Mature Secondary Structure
MKTKKVIILVGLLLSSQLTLIACQSRGNGTYPIKTKQSRKGMTSNKIKPIKKSKKTNKTH
CCCCEEEEEEEHHHCCCEEEEEEECCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHCCCHH
KGVAGVDFPTDDGFILTKDSKILSKTDQGIVVDHDGHSHFIFYADLKGSPFEYLIPKGAS
CCCCCCCCCCCCCEEEECCCHHHHCCCCCEEEECCCCEEEEEEEECCCCCCEEECCCCCC
LAKPAVAQRAASQGTSKVADPHHHYEFNPADIVAEDALGYTVRHDDHFHYILKSSLSGQT
CCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEECCCCEEEEEHHCCCCCH
QAQAKQVATRLPQTSSLVSTATANGIPGLHFPTSDGFQFNGQGIVGVTKDSILVDHDGHL
HHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCEECCCEEEEECCCCEEEECCCCC
HPISFADLRQGGWAHVADQYDPAKKAEKPAETHQTPELSEREKEYQEKLAYLAEKLGIDP
CCCCHHHHCCCCCEECCCCCCCHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCH
STIKRVETQDGKLGLEYPHHDHAHVLMLSDIEIGKDIPDPHAIEHARELEKHKVGMDTLR
HHHHHHCCCCCCEECCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHHHH
ALGFDEEVILDIVRTHDAPTPFPSNEKDPNMMKEWLATVIKLDLGSRKDPLQRKGLSLLP
HCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCC
NLETLGIGFTPIKDISPVLQFKKLKQLLMTKTGVTDYRFLDNMPQLEGIDISQNNLKDIS
CCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCHHHH
FLSKYKNLTLVAAADNGIEDIRPLGQLPNLKFLVLSNNKISDLSPLASLHQLQELHIDNN
HHHHHCCEEEEEECCCCHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCC
QITDLSPVSHKESLTVVDLSRNADVDLATLQAPKLETLMVNDTKVSHLDFLKNNPNLSSL
CCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCEEEEECCCCCHHHHHHCCCCCCCEE
SINRAQLQSLEGIEASSVIVRVEAEGNQIKSLVLKDKQGSLTFLDVTGNQLTSLEGVNNF
ECCHHHHHHHCCCCCCEEEEEEECCCCCEEEEEEECCCCCEEEEEECCCCEEECCCCCCC
TALDILSVSKNQLTNVNLSKPNKTVTNIDISHNNISLADLKLNEQHIPEAIAKNFPAVYE
EEEEEEECCCCCCCEEECCCCCCEEEEEEECCCCEEEEEEECCHHHHHHHHHCCCCCEEC
GSMVGNGTAEEKAAMATKAKESAQEASESHDYNHNHTYEDEEGHAHEHRDKDDHDHEHED
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCC
ENEAKDEQNHAD
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9541569 [H]