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The map label for this gene is yehU [C]

Identifier: 15675053

GI number: 15675053

Start: 869545

End: 871194

Strand: Direct

Name: yehU [C]

Synonym: SPy_1061

Alternate gene names: 15675053

Gene position: 869545-871194 (Clockwise)

Preceding gene: 15675052

Following gene: 15675054

Centisome position: 46.94

GC content: 35.33

Gene sequence:

>1650_bases
ATGCGAGGTGAACAGGTGGAAGAACATTTTAAAAAACAATTACAAGATGATATTTCTAGACATTTTTCGTACCAATCGTT
AATGTTATCATTGTTGCTAATTGGTCTTTTTATTATTTTTTCATTAGCGCCACAACAATTAGGCCTCTATCGTGATATCA
ATGCCACTGCAACCCGTTATCACCGTTTGATTAGCAAACAAGAAGCCTTGCTGGATGACTTAGGGAAAAATAGCTTACTA
CCTTTTTTAAATAAAAACCTCAGCACTGCTGATTTAAGCAAGCACTATTTTCATTTGCGCCATAGCAGCCAAACGTCACC
AGAACTTTTACTATTTTCACCTAGTCAAGACCTTTTATTTGCTAGTAACCCACATTTAGGAAATGTTTTTAGTAAATCTG
TTTATATTCAAGAAGTCTTGAGAGCAACTCATTCTCCAAAAACCTTGTTTAAAGATGCTATGGATAGTGAAGATGGTCAC
TACTTGATGATCATTATGCCAATGATAGATCAAAACCAACTAAAGGGATATGCTTTTTTAGTGATGAGTGGCAAAGATTT
TCTTCATCCTACAAAAACATTGACGTCAGAGTTGGTCATTGCTGATAAGCTGGACAATACGTTTACGTTTTCCAATCGTG
AGTTTATAGCATCTAGTCTAGATAAGATCAATAGCCAGTATTTACACCATTATTTTGTTTTTCAAGATAATCGAGCCTTT
ATCACAAGAAAGGTTGCCTTACAAGGAGGTCTTTGGCTTTACATGTATAGGCCCTTGATTCCAATGGTATCGGTGATGTT
ATTTTCACTTATTTCATCAGCTGTTATCTTTGTGATTTTGCAACGTAAATCAAGTGGTTTAGCTAACCGAATTGCAGCTA
AAAATTCAAGAGCAATCAATCAAATGGTTAGAGATATGAGTGCGATCTCTCGGCAAGAAAAAAGACGTATTGACCTTGAG
AGTCAAGATGAATTTCAATATTTATCTGATCAAATCAATCAAATGGTAGAGCGATTGCAACAGTTACATGATAAAACGTT
AGATTTGGAAACTCAAAAATTATTATTTGAAAAACGGATGTTAGAAGCTCAATTCAATCCGCATTTCCTCTACAATACGC
TAGAAACCATTTTGATTACGAGCCATTATGATTCTGCCCTAACAGAAAAAATTGTTATCCAATTGACAAAATTGTTGCGG
TATAGTCTCACGGATTCTAGCAAACCTGTCTTGCTCAAAGATGATTTAAGTGTCATCGAGTCTTATTTAGTGATTAATCA
GGTGCGGTTTGAAGAATTGCAATATAGCATTAACCTATCCCCAGACCTTGATAGTCTTGAAGTGCCTAAATTGTTCTTGT
TACCTTTGATAGAAAATGCCATCAAATATGGCTTGAAAGAACGACACGATGTCAAGATTAACATTGCTTGTTATTATCAA
GATGACCACATTATTTTTTCTGTGAGAGATAATGGTTCGGGAATTGATGCTCATCACCAAAAAGTGATTCGAGAGCAATT
GGAAGCTGGAGAGTCACACCATGGGTTAATTAACTCTTATCGTCGGCTTAAGTATCATTTTTCAGAAGTATCCTTGGTTT
TTGATCAAGGTGATAAACAGTTTAATGTTAGTTACCATGTTAAGGAGTAG

Upstream 100 bases:

>100_bases
TTCTTGTTTTGCTTACCTTTTTCCTTTTAAGATGATGAGACTTGTTTTGATGAAAAACGTAGTAGCATTAAGAAATTTGT
TATAATGAAAGGAGCTTAAG

Downstream 100 bases:

>100_bases
TCTATGTACAAATTAGTCATTATTGAAGATGAACATATTATTAGGAAATGGTTGCGATACGCTATTGATTATAAAGCTTT
AGATATTTTGGTCATTGGCG

Product: putative two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAPQQLGLYRDINATATRYHRLISKQEALLDDLGKNSLL
PFLNKNLSTADLSKHYFHLRHSSQTSPELLLFSPSQDLLFASNPHLGNVFSKSVYIQEVLRATHSPKTLFKDAMDSEDGH
YLMIIMPMIDQNQLKGYAFLVMSGKDFLHPTKTLTSELVIADKLDNTFTFSNREFIASSLDKINSQYLHHYFVFQDNRAF
ITRKVALQGGLWLYMYRPLIPMVSVMLFSLISSAVIFVILQRKSSGLANRIAAKNSRAINQMVRDMSAISRQEKRRIDLE
SQDEFQYLSDQINQMVERLQQLHDKTLDLETQKLLFEKRMLEAQFNPHFLYNTLETILITSHYDSALTEKIVIQLTKLLR
YSLTDSSKPVLLKDDLSVIESYLVINQVRFEELQYSINLSPDLDSLEVPKLFLLPLIENAIKYGLKERHDVKINIACYYQ
DDHIIFSVRDNGSGIDAHHQKVIREQLEAGESHHGLINSYRRLKYHFSEVSLVFDQGDKQFNVSYHVKE

Sequences:

>Translated_549_residues
MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAPQQLGLYRDINATATRYHRLISKQEALLDDLGKNSLL
PFLNKNLSTADLSKHYFHLRHSSQTSPELLLFSPSQDLLFASNPHLGNVFSKSVYIQEVLRATHSPKTLFKDAMDSEDGH
YLMIIMPMIDQNQLKGYAFLVMSGKDFLHPTKTLTSELVIADKLDNTFTFSNREFIASSLDKINSQYLHHYFVFQDNRAF
ITRKVALQGGLWLYMYRPLIPMVSVMLFSLISSAVIFVILQRKSSGLANRIAAKNSRAINQMVRDMSAISRQEKRRIDLE
SQDEFQYLSDQINQMVERLQQLHDKTLDLETQKLLFEKRMLEAQFNPHFLYNTLETILITSHYDSALTEKIVIQLTKLLR
YSLTDSSKPVLLKDDLSVIESYLVINQVRFEELQYSINLSPDLDSLEVPKLFLLPLIENAIKYGLKERHDVKINIACYYQ
DDHIIFSVRDNGSGIDAHHQKVIREQLEAGESHHGLINSYRRLKYHFSEVSLVFDQGDKQFNVSYHVKE
>Mature_549_residues
MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAPQQLGLYRDINATATRYHRLISKQEALLDDLGKNSLL
PFLNKNLSTADLSKHYFHLRHSSQTSPELLLFSPSQDLLFASNPHLGNVFSKSVYIQEVLRATHSPKTLFKDAMDSEDGH
YLMIIMPMIDQNQLKGYAFLVMSGKDFLHPTKTLTSELVIADKLDNTFTFSNREFIASSLDKINSQYLHHYFVFQDNRAF
ITRKVALQGGLWLYMYRPLIPMVSVMLFSLISSAVIFVILQRKSSGLANRIAAKNSRAINQMVRDMSAISRQEKRRIDLE
SQDEFQYLSDQINQMVERLQQLHDKTLDLETQKLLFEKRMLEAQFNPHFLYNTLETILITSHYDSALTEKIVIQLTKLLR
YSLTDSSKPVLLKDDLSVIESYLVINQVRFEELQYSINLSPDLDSLEVPKLFLLPLIENAIKYGLKERHDVKINIACYYQ
DDHIIFSVRDNGSGIDAHHQKVIREQLEAGESHHGLINSYRRLKYHFSEVSLVFDQGDKQFNVSYHVKE

Specific function: Probable member of the two-component regulatory system SE_0166/SE_0165. May activate SE_0165 by phosphorylation [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=149, Percent_Identity=32.8859060402685, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788723, Length=214, Percent_Identity=29.9065420560748, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR010559 [H]

Pfam domain/function: PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 63652; Mature: 63652

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS50885 HAMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAPQQLGLYRDINATATRY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHH
HRLISKQEALLDDLGKNSLLPFLNKNLSTADLSKHYFHLRHSSQTSPELLLFSPSQDLLF
HHHHHHHHHHHHHCCCCCCCHHHCCCCCHHHHHHHHHEEECCCCCCCCEEEECCCCCCEE
ASNPHLGNVFSKSVYIQEVLRATHSPKTLFKDAMDSEDGHYLMIIMPMIDQNQLKGYAFL
ECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEEEECCCCCCCCCEEEE
VMSGKDFLHPTKTLTSELVIADKLDNTFTFSNREFIASSLDKINSQYLHHYFVFQDNRAF
EECCCCCCCCHHHHHHHHHEEECCCCCEEECCHHHHHHHHHHHHHHHEEEEEEEECCCEE
ITRKVALQGGLWLYMYRPLIPMVSVMLFSLISSAVIFVILQRKSSGLANRIAAKNSRAIN
EEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHH
QMVRDMSAISRQEKRRIDLESQDEFQYLSDQINQMVERLQQLHDKTLDLETQKLLFEKRM
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LEAQFNPHFLYNTLETILITSHYDSALTEKIVIQLTKLLRYSLTDSSKPVLLKDDLSVIE
HHHCCCCHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHH
SYLVINQVRFEELQYSINLSPDLDSLEVPKLFLLPLIENAIKYGLKERHDVKINIACYYQ
HHHHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEE
DDHIIFSVRDNGSGIDAHHQKVIREQLEAGESHHGLINSYRRLKYHFSEVSLVFDQGDKQ
CCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCE
FNVSYHVKE
EEEEEEECC
>Mature Secondary Structure
MRGEQVEEHFKKQLQDDISRHFSYQSLMLSLLLIGLFIIFSLAPQQLGLYRDINATATRY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHHHH
HRLISKQEALLDDLGKNSLLPFLNKNLSTADLSKHYFHLRHSSQTSPELLLFSPSQDLLF
HHHHHHHHHHHHHCCCCCCCHHHCCCCCHHHHHHHHHEEECCCCCCCCEEEECCCCCCEE
ASNPHLGNVFSKSVYIQEVLRATHSPKTLFKDAMDSEDGHYLMIIMPMIDQNQLKGYAFL
ECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEEEECCCCCCCCCEEEE
VMSGKDFLHPTKTLTSELVIADKLDNTFTFSNREFIASSLDKINSQYLHHYFVFQDNRAF
EECCCCCCCCHHHHHHHHHEEECCCCCEEECCHHHHHHHHHHHHHHHEEEEEEEECCCEE
ITRKVALQGGLWLYMYRPLIPMVSVMLFSLISSAVIFVILQRKSSGLANRIAAKNSRAIN
EEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHH
QMVRDMSAISRQEKRRIDLESQDEFQYLSDQINQMVERLQQLHDKTLDLETQKLLFEKRM
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LEAQFNPHFLYNTLETILITSHYDSALTEKIVIQLTKLLRYSLTDSSKPVLLKDDLSVIE
HHHCCCCHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHH
SYLVINQVRFEELQYSINLSPDLDSLEVPKLFLLPLIENAIKYGLKERHDVKINIACYYQ
HHHHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEE
DDHIIFSVRDNGSGIDAHHQKVIREQLEAGESHHGLINSYRRLKYHFSEVSLVFDQGDKQ
CCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCE
FNVSYHVKE
EEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12950922 [H]