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The map label for this gene is mur1.2 [C]

Identifier: 15674890

GI number: 15674890

Start: 709084

End: 709791

Strand: Direct

Name: mur1.2 [C]

Synonym: SPy_0857

Alternate gene names: 15674890

Gene position: 709084-709791 (Clockwise)

Preceding gene: 15674889

Following gene: 15674892

Centisome position: 38.28

GC content: 38.56

Gene sequence:

>708_bases
ATGACAAAAAAGAAAGGTAAGCTTGTACTTATCAGTCTTTTTGTTCTAGCAGCTTGTTTAGGAGCTTATAGTGCAATGAG
ACAATCTCATAAAACTTCAAACGTGTCAGCTGAGACTATCGCCAGTTCTTCAACCCGACATTTTATTGATGAAATTGGTC
CAACTGCTAGTACTATTGGTCAAGAACGTGATCTTTATGCGTCTGTTATGATAGCACAAGCGATTTTAGAATCAAGTAAT
GGTAAATCAAGTCTAAGTCAAGCACCTTATTATAATTTTTTCGGTATTAAGGGTGCCTATAACGGTTCTTCTGTGACGAT
GTCAACTTGGGAAGATGATGGTAATGGCAATACCTATACGATTGATCAAGCCTTTAGAGCTTATCCAAGTATTGCAGACT
CCCTTAATGACTACGCGGACTTGCTAAGTTCTAGCACTTATATAGGTGCTAGAAAATCAAACACGCTATCGTATCAAGAT
GCTACAGCAGCTCTAACTGGCTTATACGCTACAGACACCAGTTATAACTTAAAACTAAATAATATTATTGCAACCTATGG
TTTGACGGCTTATGATGTTGCTAATAGCTCAGCTCAAGAAACTGGTCTAGCAACTTCGGGTTATGTTTGGAATGAATATC
GTCGTAATTACACTGATGCGGAGACCCTAGCAGTTGATGAGGCTTGGGCTAAACGCATGACTTATTAA

Upstream 100 bases:

>100_bases
AAGTTATCAATCTCATTAAATTATCTGTGGAAAAGTTAATTTAAACGTTCGTGTGCTATAATAGAAACATAGAAAATGAA
TAAAAAAGGATATATGAATA

Downstream 100 bases:

>100_bases
TGTAACACTAACAACAATCTGCTTGCACTGACCCCAAAAAAGCTGGATACTCTATTTTAAGTAAAGGATTTAGTTCTGTA
TTGTACAGAACTAAATCCTT

Product: putative peptidoglycan hydrolase

Products: NA

Alternate protein names: Beta-glycosidase; Peptidoglycan hydrolase [H]

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MTKKKGKLVLISLFVLAACLGAYSAMRQSHKTSNVSAETIASSSTRHFIDEIGPTASTIGQERDLYASVMIAQAILESSN
GKSSLSQAPYYNFFGIKGAYNGSSVTMSTWEDDGNGNTYTIDQAFRAYPSIADSLNDYADLLSSSTYIGARKSNTLSYQD
ATAALTGLYATDTSYNLKLNNIIATYGLTAYDVANSSAQETGLATSGYVWNEYRRNYTDAETLAVDEAWAKRMTY

Sequences:

>Translated_235_residues
MTKKKGKLVLISLFVLAACLGAYSAMRQSHKTSNVSAETIASSSTRHFIDEIGPTASTIGQERDLYASVMIAQAILESSN
GKSSLSQAPYYNFFGIKGAYNGSSVTMSTWEDDGNGNTYTIDQAFRAYPSIADSLNDYADLLSSSTYIGARKSNTLSYQD
ATAALTGLYATDTSYNLKLNNIIATYGLTAYDVANSSAQETGLATSGYVWNEYRRNYTDAETLAVDEAWAKRMTY
>Mature_234_residues
TKKKGKLVLISLFVLAACLGAYSAMRQSHKTSNVSAETIASSSTRHFIDEIGPTASTIGQERDLYASVMIAQAILESSNG
KSSLSQAPYYNFFGIKGAYNGSSVTMSTWEDDGNGNTYTIDQAFRAYPSIADSLNDYADLLSSSTYIGARKSNTLSYQDA
TAALTGLYATDTSYNLKLNNIIATYGLTAYDVANSSAQETGLATSGYVWNEYRRNYTDAETLAVDEAWAKRMTY

Specific function: Hydrolyzes the cell wall of E.faecalis and M.lysodeikticus. May play an important role in cell wall growth and cell separation [H]

COG id: COG1705

COG function: function code NU; Muramidase (flagellum-specific)

Gene ontology:

Cell location: Secreted (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1787321, Length=144, Percent_Identity=30.5555555555556, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013338
- InterPro:   IPR002901
- InterPro:   IPR018392
- InterPro:   IPR002482 [H]

Pfam domain/function: PF01832 Glucosaminidase; PF01476 LysM [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 25511; Mature: 25380

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKKGKLVLISLFVLAACLGAYSAMRQSHKTSNVSAETIASSSTRHFIDEIGPTASTIG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHCCCHHHHC
QERDLYASVMIAQAILESSNGKSSLSQAPYYNFFGIKGAYNGSSVTMSTWEDDGNGNTYT
CHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCEEEECCCCCCCCEEEEEECCCCCCCCEEE
IDQAFRAYPSIADSLNDYADLLSSSTYIGARKSNTLSYQDATAALTGLYATDTSYNLKLN
HHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCHHHHHHHHEEECCCCCEEEEC
NIIATYGLTAYDVANSSAQETGLATSGYVWNEYRRNYTDAETLAVDEAWAKRMTY
CEEECCCCCHHHHCCCCHHHCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TKKKGKLVLISLFVLAACLGAYSAMRQSHKTSNVSAETIASSSTRHFIDEIGPTASTIG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHCCCHHHHC
QERDLYASVMIAQAILESSNGKSSLSQAPYYNFFGIKGAYNGSSVTMSTWEDDGNGNTYT
CHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCEEEECCCCCCCCEEEEEECCCCCCCCEEE
IDQAFRAYPSIADSLNDYADLLSSSTYIGARKSNTLSYQDATAALTGLYATDTSYNLKLN
HHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCHHHHHHHHEEECCCCCEEEEC
NIIATYGLTAYDVANSSAQETGLATSGYVWNEYRRNYTDAETLAVDEAWAKRMTY
CEEECCCCCHHHHCCCCHHHCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1679432; 12663927 [H]