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The map label for this gene is cmk

Identifier: 15674845

GI number: 15674845

Start: 660698

End: 661378

Strand: Direct

Name: cmk

Synonym: SPy_0803

Alternate gene names: 15674845

Gene position: 660698-661378 (Clockwise)

Preceding gene: 15674844

Following gene: 15674846

Centisome position: 35.67

GC content: 40.09

Gene sequence:

>681_bases
ATGAAAGCAATTAAAATTGCGATTGATGGGCCAGCTTCAAGTGGAAAAAGTACAGTAGCCAAGATTATTGCAAAAAATCT
TGGCTATACTTATCTAGATACTGGTGCTATGTATCGCTCAGCAACTTATATCGCACTGACACATGGCTATACGGGTAAAG
AAGTAGCCCTTATCTTAGAGGAACTTGAGAAAAATCCTATTTTCTTTAAAAAAGCAAAAGATGGCTCCCAATTAGTTTTT
CTTGGGGATGAGGACGTGACCTTAGCCATTAGGCAAAATGATGTGACTAACAATGTTTCTTGGATCTCAGCTTTGCCAGA
AATTAGAGAAGAGCTGGTTCATCAACAAAGACGCATTGCACAAGCTGGTGGCATTATCATGGATGGTCGTGACATTGGAA
CGGTTGTTCTCCCAGATGCGGAACTAAAAATCTTTTTAGTGGCTTCTGTCGAAGAGCGGGCAGAGCGCCGCTATAAAGAA
AACCTAGAAAAAGGAATTGAATCAGATTTTGAGACGCTAAAAGAAGAGATTGCAGCTCGTGATTACAAGGATAGTCATCG
TAAGGTTTCACCTCTAAAAGCAGCTGAAGATGCCCTTATTTTTGATACCACAGGTGTTTCTATTGATGGCGTGGTGCAAT
TTATCCAAGAAAAAGCAGAAAAAATAGTTGACATGTCCTAG

Upstream 100 bases:

>100_bases
TGGAGCAGTTACAAGCACTTAATCCAGAGCACATGACTCAAGGATATTGGTATGCCAATCCAGGAGATCAAGTCACTATT
AAATAATTGAAGAGGAAAAA

Downstream 100 bases:

>100_bases
AGCCTATGTTAGAATAGTAACAATGAGAAAAGTAGAAGTGAGAGCTTCTCGCCTTGCGACTTAGGTTGTCTGGCCCTAAC
ATGTCAAATTCCTATGGAAT

Product: cytidylate kinase

Products: NA

Alternate protein names: CK; Cytidine monophosphate kinase; CMP kinase

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MKAIKIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYIALTHGYTGKEVALILEELEKNPIFFKKAKDGSQLVF
LGDEDVTLAIRQNDVTNNVSWISALPEIREELVHQQRRIAQAGGIIMDGRDIGTVVLPDAELKIFLVASVEERAERRYKE
NLEKGIESDFETLKEEIAARDYKDSHRKVSPLKAAEDALIFDTTGVSIDGVVQFIQEKAEKIVDMS

Sequences:

>Translated_226_residues
MKAIKIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYIALTHGYTGKEVALILEELEKNPIFFKKAKDGSQLVF
LGDEDVTLAIRQNDVTNNVSWISALPEIREELVHQQRRIAQAGGIIMDGRDIGTVVLPDAELKIFLVASVEERAERRYKE
NLEKGIESDFETLKEEIAARDYKDSHRKVSPLKAAEDALIFDTTGVSIDGVVQFIQEKAEKIVDMS
>Mature_226_residues
MKAIKIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYIALTHGYTGKEVALILEELEKNPIFFKKAKDGSQLVF
LGDEDVTLAIRQNDVTNNVSWISALPEIREELVHQQRRIAQAGGIIMDGRDIGTVVLPDAELKIFLVASVEERAERRYKE
NLEKGIESDFETLKEEIAARDYKDSHRKVSPLKAAEDALIFDTTGVSIDGVVQFIQEKAEKIVDMS

Specific function: ATP, Datp, And GTP Are Equally Effective As Phosphate Donors. CMP And Dcmp Are The Best Phosphate Acceptors. [C]

COG id: COG0283

COG function: function code F; Cytidylate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidylate kinase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1787139, Length=209, Percent_Identity=43.5406698564593, Blast_Score=158, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KCY_STRP1 (Q9A0F0)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_269019.1
- RefSeq:   YP_281981.1
- ProteinModelPortal:   Q9A0F0
- SMR:   Q9A0F0
- EnsemblBacteria:   EBSTRT00000001338
- EnsemblBacteria:   EBSTRT00000027741
- GeneID:   3572286
- GeneID:   900976
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_0803
- KEGG:   spz:M5005_Spy_0618
- GeneTree:   EBGT00050000027971
- HOGENOM:   HBG354377
- OMA:   DIGTVIC
- ProtClustDB:   PRK00023
- BioCyc:   SPYO160490:SPY0803-MONOMER
- BioCyc:   SPYO293653:M5005_SPY0618-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00238
- InterPro:   IPR003136
- InterPro:   IPR011994
- PANTHER:   PTHR21299:SF2
- TIGRFAMs:   TIGR00017

Pfam domain/function: PF02224 Cytidylate_kin

EC number: =2.7.4.14

Molecular weight: Translated: 25035; Mature: 25035

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAIKIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYIALTHGYTGKEVALILE
CCEEEEEECCCCCCCHHHHHHHHHHHCCCEEEECCHHHHCEEEEEEECCCCCHHHHHHHH
ELEKNPIFFKKAKDGSQLVFLGDEDVTLAIRQNDVTNNVSWISALPEIREELVHQQRRIA
HHCCCCEEEEECCCCCEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QAGGIIMDGRDIGTVVLPDAELKIFLVASVEERAERRYKENLEKGIESDFETLKEEIAAR
HHCCEEEECCCCCEEEECCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DYKDSHRKVSPLKAAEDALIFDTTGVSIDGVVQFIQEKAEKIVDMS
CCCHHCCCCCCCHHCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKAIKIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYIALTHGYTGKEVALILE
CCEEEEEECCCCCCCHHHHHHHHHHHCCCEEEECCHHHHCEEEEEEECCCCCHHHHHHHH
ELEKNPIFFKKAKDGSQLVFLGDEDVTLAIRQNDVTNNVSWISALPEIREELVHQQRRIA
HHCCCCEEEEECCCCCEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QAGGIIMDGRDIGTVVLPDAELKIFLVASVEERAERRYKENLEKGIESDFETLKEEIAAR
HHCCEEEECCCCCEEEECCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DYKDSHRKVSPLKAAEDALIFDTTGVSIDGVVQFIQEKAEKIVDMS
CCCHHCCCCCCCHHCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296