BacMap

Definition	Streptococcus pyogenes M1 GAS chromosome, complete genome.
Accession	NC_002737
Length	1,852,441

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The map label for this gene is rgpDc [H]

Identifier: 15674833

GI number: 15674833

Start: 647705

End: 648910

Strand: Direct

Name: rgpDc [H]

Synonym: SPy_0790

Alternate gene names: 15674833

Gene position: 647705-648910 (Clockwise)

Preceding gene: 15674832

Following gene: 15674834

Centisome position: 34.96

GC content: 35.07

Gene sequence:

>1206_bases
ATGATTAATAGAGAAATTGCAGTAAAAGTACAGCATGTTAGTAAAACGTTTAAACTGCCTACAGAAGCAACTAAAAGTTT
TCGCACGACTCTGGTTAATCGCCTAAGAGGGATTAAAGGATTTACTGAACAACATGTGCTAAAAGATATTAACTTTGATG
TTTATAAAGGCGATTTTTTTGGAATTGTTGGGCGTAACGGCTCAGGAAAATCAACGCTCCTTAAAATTATTTCCCAGATC
TATGTTCCAGAAAAAGGGCAGGTTACAGTAGATGGGAAGATGGTTTCTTTTATAGAGCTTGGAGTGGGATTCAATCCAGA
ATTAACAGGACGAGAAAACGTCTATATGAACGGCGCCATGCTGGGATTTACCAAAGACGAAGTTGATGATATGTACAATG
ATATTGTTGATTTTGCAGAGTTGCATCATTTTATGAATCAAAAATTAAAAAATTATTCTTCTGGCATGCAGGTACGTTTA
GCATTTTCAGTGGCTATTAAAGCCCAAGGTGACGTTCTTATTTTAGATGAGGTGCTTGCTGTAGGAGATGAAGCTTTTCA
GCGAAAATGTAATGATTATTTTATGGAAAGAAAAGACAGTGGTAAGACGACTATTTTAGTGACACATGATATGGGAGCTG
TTAAGAAGTATTGTAACCGTGCAGTTCTTATTGAAGATGGTCTTGTTAAAGCATATGGAGAACCATTTGATGTTGCTAAT
CAGTATAGTGTAGATAATACAGAGACAGCTGAGGATGCAATGAATGCTGAAAAAATATCTGTATCTGATATTGCCAAAGA
TTTGAAAGTGTCATTAATCTCAAATCCAAGAATAACACCAAATGACACAATCACATTTGAAGTTTCTTATGAAGTTTTAA
AAGATGATTTTACCTACATTGCCTTTTCTTTAACGGATATTGATAGAAACATTTGGGTTTACAACGACAATTCTTTAGAT
TATCCAACACAAGGTATAGGTAGAAAATGCATTTCCTACCAATGTCAACTATCTCAACTTAATGATATAAAACTAAAATT
AGAAGTAACTGTCCGAGATAAGAACGGTCAGATGCTACTCTTTTCAACAGCAGAACAATCACCCCAGATAGTGATTCAAA
GAAACGATATTGATCAAGATGATCTGTCAGCTCTAGATTCAGCAAGTGGCTTGTATCAACGTAATGGGAAGTGGGTTTTT
CATTAA

Upstream 100 bases:

>100_bases
GGTTTTACATTGTTATTCCATATTTAGTACCATTTGTTATATTATTTATTGGCATCTTTGTCTTTAAGAAAAATGCCGAT
AGATTTGCGGAGATTATTTA

Downstream 100 bases:

>100_bases
TGAGTAATAGCTAGAAGGGAATTTATGTATAAAGTTTCAATTATTTGCACCAATTATAACAAAGCTCCTTGGATATCTGA
TGCACTTGACAGTTTTTTAA

Product: ABC transporter ATP-binding protein

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MINREIAVKVQHVSKTFKLPTEATKSFRTTLVNRLRGIKGFTEQHVLKDINFDVYKGDFFGIVGRNGSGKSTLLKIISQI
YVPEKGQVTVDGKMVSFIELGVGFNPELTGRENVYMNGAMLGFTKDEVDDMYNDIVDFAELHHFMNQKLKNYSSGMQVRL
AFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKDSGKTTILVTHDMGAVKKYCNRAVLIEDGLVKAYGEPFDVAN
QYSVDNTETAEDAMNAEKISVSDIAKDLKVSLISNPRITPNDTITFEVSYEVLKDDFTYIAFSLTDIDRNIWVYNDNSLD
YPTQGIGRKCISYQCQLSQLNDIKLKLEVTVRDKNGQMLLFSTAEQSPQIVIQRNDIDQDDLSALDSASGLYQRNGKWVF
H

Sequences:

>Translated_401_residues
MINREIAVKVQHVSKTFKLPTEATKSFRTTLVNRLRGIKGFTEQHVLKDINFDVYKGDFFGIVGRNGSGKSTLLKIISQI
YVPEKGQVTVDGKMVSFIELGVGFNPELTGRENVYMNGAMLGFTKDEVDDMYNDIVDFAELHHFMNQKLKNYSSGMQVRL
AFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKDSGKTTILVTHDMGAVKKYCNRAVLIEDGLVKAYGEPFDVAN
QYSVDNTETAEDAMNAEKISVSDIAKDLKVSLISNPRITPNDTITFEVSYEVLKDDFTYIAFSLTDIDRNIWVYNDNSLD
YPTQGIGRKCISYQCQLSQLNDIKLKLEVTVRDKNGQMLLFSTAEQSPQIVIQRNDIDQDDLSALDSASGLYQRNGKWVF
H
>Mature_401_residues
MINREIAVKVQHVSKTFKLPTEATKSFRTTLVNRLRGIKGFTEQHVLKDINFDVYKGDFFGIVGRNGSGKSTLLKIISQI
YVPEKGQVTVDGKMVSFIELGVGFNPELTGRENVYMNGAMLGFTKDEVDDMYNDIVDFAELHHFMNQKLKNYSSGMQVRL
AFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKDSGKTTILVTHDMGAVKKYCNRAVLIEDGLVKAYGEPFDVAN
QYSVDNTETAEDAMNAEKISVSDIAKDLKVSLISNPRITPNDTITFEVSYEVLKDDFTYIAFSLTDIDRNIWVYNDNSLD
YPTQGIGRKCISYQCQLSQLNDIKLKLEVTVRDKNGQMLLFSTAEQSPQIVIQRNDIDQDDLSALDSASGLYQRNGKWVF
H

Specific function: Influences the expression of the surface array protein gene (vapA). May have both regulatory and transport activities [H]

COG id: COG1134

COG function: function code GM; ABC-type polysaccharide/polyol phosphate transport system, ATPase component

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI31657092, Length=211, Percent_Identity=24.1706161137441, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI116734710, Length=266, Percent_Identity=23.6842105263158, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI153792144, Length=213, Percent_Identity=24.4131455399061, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI105990541, Length=204, Percent_Identity=25.9803921568627, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI27477115, Length=211, Percent_Identity=27.9620853080569, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI27436953, Length=204, Percent_Identity=25.4901960784314, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI6005701, Length=194, Percent_Identity=25.2577319587629, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI47078218, Length=251, Percent_Identity=21.9123505976096, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI45446740, Length=251, Percent_Identity=21.9123505976096, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI150417984, Length=206, Percent_Identity=26.2135922330097, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI27262624, Length=211, Percent_Identity=22.2748815165877, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI27262626, Length=211, Percent_Identity=22.2748815165877, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI21536376, Length=204, Percent_Identity=25.4901960784314, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI89111135, Length=208, Percent_Identity=27.4038461538462, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI27881501, Length=244, Percent_Identity=22.5409836065574, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI30795238, Length=244, Percent_Identity=22.5409836065574, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1790467, Length=218, Percent_Identity=29.3577981651376, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI87081791, Length=232, Percent_Identity=23.7068965517241, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787029, Length=217, Percent_Identity=29.0322580645161, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1789032, Length=259, Percent_Identity=21.6216216216216, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1787089, Length=221, Percent_Identity=24.8868778280543, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87081709, Length=214, Percent_Identity=25.2336448598131, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790525, Length=261, Percent_Identity=25.6704980842912, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786398, Length=197, Percent_Identity=26.3959390862944, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790739, Length=233, Percent_Identity=24.8927038626609, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789672, Length=216, Percent_Identity=27.3148148148148, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1787370, Length=217, Percent_Identity=23.963133640553, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1786319, Length=194, Percent_Identity=27.319587628866, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1788450, Length=222, Percent_Identity=24.7747747747748, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786803, Length=228, Percent_Identity=23.2456140350877, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87081782, Length=207, Percent_Identity=25.1207729468599, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI48994943, Length=217, Percent_Identity=25.3456221198157, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788225, Length=217, Percent_Identity=24.4239631336406, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788761, Length=212, Percent_Identity=23.1132075471698, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788210, Length=142, Percent_Identity=32.3943661971831, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI48995001, Length=205, Percent_Identity=24.8780487804878, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789593, Length=228, Percent_Identity=22.8070175438596, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI87082267, Length=205, Percent_Identity=24.390243902439, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788540, Length=212, Percent_Identity=26.4150943396226, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1786703, Length=206, Percent_Identity=26.6990291262136, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1787105, Length=199, Percent_Identity=26.6331658291457, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1789751, Length=241, Percent_Identity=22.8215767634855, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1790190, Length=212, Percent_Identity=26.4150943396226, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1787712, Length=200, Percent_Identity=24.5, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17565586, Length=216, Percent_Identity=25, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17510237, Length=263, Percent_Identity=22.8136882129278, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI115533608, Length=205, Percent_Identity=24.390243902439, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71992290, Length=207, Percent_Identity=28.0193236714976, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17565938, Length=206, Percent_Identity=27.1844660194175, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71983523, Length=223, Percent_Identity=24.2152466367713, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71983510, Length=223, Percent_Identity=24.2152466367713, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71983516, Length=223, Percent_Identity=24.2152466367713, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17533971, Length=206, Percent_Identity=29.126213592233, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17511077, Length=209, Percent_Identity=27.7511961722488, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193209708, Length=209, Percent_Identity=25.3588516746411, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17543740, Length=205, Percent_Identity=25.3658536585366, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6322640, Length=205, Percent_Identity=26.8292682926829, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321720, Length=226, Percent_Identity=24.3362831858407, Blast_Score=63, Evalue=8e-11,
Organism=Drosophila melanogaster, GI221512771, Length=215, Percent_Identity=26.046511627907, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI116007184, Length=228, Percent_Identity=23.2456140350877, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI221500365, Length=228, Percent_Identity=23.2456140350877, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24582014, Length=220, Percent_Identity=25.9090909090909, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24582012, Length=220, Percent_Identity=25.9090909090909, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28573571, Length=216, Percent_Identity=25.9259259259259, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24666092, Length=314, Percent_Identity=23.5668789808917, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28573573, Length=207, Percent_Identity=25.1207729468599, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI85725262, Length=284, Percent_Identity=24.2957746478873, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24643674, Length=221, Percent_Identity=24.4343891402715, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24648314, Length=288, Percent_Identity=22.5694444444444, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI281363262, Length=211, Percent_Identity=27.0142180094787, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24653245, Length=211, Percent_Identity=27.0142180094787, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281362751, Length=178, Percent_Identity=28.0898876404494, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24650853, Length=178, Percent_Identity=28.0898876404494, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24650855, Length=178, Percent_Identity=28.0898876404494, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24659289, Length=202, Percent_Identity=28.2178217821782, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 45232; Mature: 45232

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINREIAVKVQHVSKTFKLPTEATKSFRTTLVNRLRGIKGFTEQHVLKDINFDVYKGDFF
CCCCEEEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEECCEE
GIVGRNGSGKSTLLKIISQIYVPEKGQVTVDGKMVSFIELGVGFNPELTGRENVYMNGAM
EEEECCCCCHHHHHHHHHHHCCCCCCCEEECCCEEEEEEECCCCCCCCCCCCCEEECCEE
LGFTKDEVDDMYNDIVDFAELHHFMNQKLKNYSSGMQVRLAFSVAIKAQGDVLILDEVLA
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCEEEEHHHHH
VGDEAFQRKCNDYFMERKDSGKTTILVTHDMGAVKKYCNRAVLIEDGLVKAYGEPFDVAN
CCCHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHCCEEEEECCHHHHCCCCCCCCC
QYSVDNTETAEDAMNAEKISVSDIAKDLKVSLISNPRITPNDTITFEVSYEVLKDDFTYI
CCCCCCCCCHHHHCCCCEEEHHHHHHHHEEEEECCCCCCCCCEEEEEEEEEEHHCCCEEE
AFSLTDIDRNIWVYNDNSLDYPTQGIGRKCISYQCQLSQLNDIKLKLEVTVRDKNGQMLL
EEEEEECCCEEEEEECCCCCCCCHHHCHHHHHEEEEECCCCCEEEEEEEEEECCCCCEEE
FSTAEQSPQIVIQRNDIDQDDLSALDSASGLYQRNGKWVFH
EECCCCCCEEEEEECCCCHHHHHHHHHCCCHHHCCCCEECC
>Mature Secondary Structure
MINREIAVKVQHVSKTFKLPTEATKSFRTTLVNRLRGIKGFTEQHVLKDINFDVYKGDFF
CCCCEEEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEECCEE
GIVGRNGSGKSTLLKIISQIYVPEKGQVTVDGKMVSFIELGVGFNPELTGRENVYMNGAM
EEEECCCCCHHHHHHHHHHHCCCCCCCEEECCCEEEEEEECCCCCCCCCCCCCEEECCEE
LGFTKDEVDDMYNDIVDFAELHHFMNQKLKNYSSGMQVRLAFSVAIKAQGDVLILDEVLA
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCCCEEEEHHHHH
VGDEAFQRKCNDYFMERKDSGKTTILVTHDMGAVKKYCNRAVLIEDGLVKAYGEPFDVAN
CCCHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHCCEEEEECCHHHHCCCCCCCCC
QYSVDNTETAEDAMNAEKISVSDIAKDLKVSLISNPRITPNDTITFEVSYEVLKDDFTYI
CCCCCCCCCHHHHCCCCEEEHHHHHHHHEEEEECCCCCCCCCEEEEEEEEEEHHCCCEEE
AFSLTDIDRNIWVYNDNSLDYPTQGIGRKCISYQCQLSQLNDIKLKLEVTVRDKNGQMLL
EEEEEECCCEEEEEECCCCCCCCHHHCHHHHHEEEEECCCCCEEEEEEEEEECCCCCEEE
FSTAEQSPQIVIQRNDIDQDDLSALDSASGLYQRNGKWVFH
EECCCCCCEEEEEECCCCHHHHHHHHHCCCHHHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8491726 [H]