| Definition | Streptococcus pyogenes M1 GAS chromosome, complete genome. |
|---|---|
| Accession | NC_002737 |
| Length | 1,852,441 |
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The map label for this gene is ftsX [H]
Identifier: 15674715
GI number: 15674715
Start: 517886
End: 518824
Strand: Direct
Name: ftsX [H]
Synonym: SPy_0645
Alternate gene names: 15674715
Gene position: 517886-518824 (Clockwise)
Preceding gene: 15674714
Following gene: 15674717
Centisome position: 27.96
GC content: 35.89
Gene sequence:
>939_bases ATGGTTACGATGATTAGATACTTTTTCCGTCATATTTGGGAATCCATTAAAAATCTTAAACGCAACTTTTGGATGACATT TGCTTCAGTTAGTATGGTGGCTGTTACATTGACTTTAGTTGGTGTTTTTGCGGCGACATTGTTGAATATACAGCGTGTTG CTTCGGGTGTTGAAAATAATGTCCATATCAATACCTACTTACAAGTTGATTCAACTGATGCTGCAAAAGTTATTCAAAAT ACTGCCGGTGAACCTGTTAATAACGATAACTACCACAGTGTTTACGACAAAATTGCTCAGATAAAAGGTGTCAAAAAGAT TACATTTTCTAGCAAGGATGAACAATTGAAAAAATTGCAAGAAACCTTAGGTGATGTTTGGAATATGTATGACCAAGACA CTAATCCGCTCCAAGATATCTATCTTATTGAGACCCAGACGCCTAAACAAGTTAAGGCGATCACTAAAAAGATCAGAACG ATTGAAGGCGTAGAAGCCGCAGATTATGGAGGGATTAACTCCGATAAACTATTTAAGTTTTCAACATTAATTCAAACTTG GGGGCTGATCGGAACAGCAATGCTATTATTTGTAGCTGTCTTTCTCATTTCAAACACTATTCGTATGACTATTATGTCTC GTAAACGTGACATTGAAATTATGCGGTTAGTTGGTGCTAAAAATTCTTATATTCGAGGGCCTTTCTTTTTTGAAGGGGCT TGGGTTGGCTTGTTAGGAGCTGTTTTACCATCTCTTCTGATTTATTATGGATATGATCTTGTTTATAAGCATTTTGCACA AGAATTACAACGTAATAATCTCTCGATGTATCCGCTTGATCCTTATGTATATTACCTGATTGGTGCTTTGTTTGTCATAG GTATTATGATTGGTTCGCTTGGTTCAGTGCTTTCTATGAGACGTTATTTAAAATTCTAA
Upstream 100 bases:
>100_bases TTAATGGCGACACACAACAGTCATATTGTGAATACATTCCGTCATCGTGTTGTTGCTATTGAAGATGGTCGCATAGTACG TGATGAAGAAAAAGGAGATT
Downstream 100 bases:
>100_bases AAAAAGCGCTGCTGACGAAACGTAGCGACCCTCAAAAGTTGGACCTCTTATGTTATTCCAAGGACCTCGTTTTGTATTGC ACAGGACTGGTCCTTTTCAT
Product: putative cell-division protein
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 312; Mature: 312
Protein sequence:
>312_residues MVTMIRYFFRHIWESIKNLKRNFWMTFASVSMVAVTLTLVGVFAATLLNIQRVASGVENNVHINTYLQVDSTDAAKVIQN TAGEPVNNDNYHSVYDKIAQIKGVKKITFSSKDEQLKKLQETLGDVWNMYDQDTNPLQDIYLIETQTPKQVKAITKKIRT IEGVEAADYGGINSDKLFKFSTLIQTWGLIGTAMLLFVAVFLISNTIRMTIMSRKRDIEIMRLVGAKNSYIRGPFFFEGA WVGLLGAVLPSLLIYYGYDLVYKHFAQELQRNNLSMYPLDPYVYYLIGALFVIGIMIGSLGSVLSMRRYLKF
Sequences:
>Translated_312_residues MVTMIRYFFRHIWESIKNLKRNFWMTFASVSMVAVTLTLVGVFAATLLNIQRVASGVENNVHINTYLQVDSTDAAKVIQN TAGEPVNNDNYHSVYDKIAQIKGVKKITFSSKDEQLKKLQETLGDVWNMYDQDTNPLQDIYLIETQTPKQVKAITKKIRT IEGVEAADYGGINSDKLFKFSTLIQTWGLIGTAMLLFVAVFLISNTIRMTIMSRKRDIEIMRLVGAKNSYIRGPFFFEGA WVGLLGAVLPSLLIYYGYDLVYKHFAQELQRNNLSMYPLDPYVYYLIGALFVIGIMIGSLGSVLSMRRYLKF >Mature_312_residues MVTMIRYFFRHIWESIKNLKRNFWMTFASVSMVAVTLTLVGVFAATLLNIQRVASGVENNVHINTYLQVDSTDAAKVIQN TAGEPVNNDNYHSVYDKIAQIKGVKKITFSSKDEQLKKLQETLGDVWNMYDQDTNPLQDIYLIETQTPKQVKAITKKIRT IEGVEAADYGGINSDKLFKFSTLIQTWGLIGTAMLLFVAVFLISNTIRMTIMSRKRDIEIMRLVGAKNSYIRGPFFFEGA WVGLLGAVLPSLLIYYGYDLVYKHFAQELQRNNLSMYPLDPYVYYLIGALFVIGIMIGSLGSVLSMRRYLKF
Specific function: Part of the ABC transporter ftsEX involved in sporulation. May act as an importer, possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation. Acts upstream of the histidine kinases KinA, KinB and KInC, the Rap
COG id: COG2177
COG function: function code D; Cell division protein
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein (Probable). Note=Unlike the E.coli ortholog, localization is not restricted to division septa, nor is it dependent on ftsZ [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily [H]
Homologues:
Organism=Escherichia coli, GI1789872, Length=257, Percent_Identity=26.4591439688716, Blast_Score=79, Evalue=4e-16,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003838 [H]
Pfam domain/function: PF02687 FtsX [H]
EC number: NA
Molecular weight: Translated: 35560; Mature: 35560
Theoretical pI: Translated: 9.76; Mature: 9.76
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 3.8 %Met (Translated Protein) 3.8 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 3.8 %Met (Mature Protein) 3.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVTMIRYFFRHIWESIKNLKRNFWMTFASVSMVAVTLTLVGVFAATLLNIQRVASGVENN CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC VHINTYLQVDSTDAAKVIQNTAGEPVNNDNYHSVYDKIAQIKGVKKITFSSKDEQLKKLQ EEEEEEEEECCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHEECCCHHHHHHHHH ETLGDVWNMYDQDTNPLQDIYLIETQTPKQVKAITKKIRTIEGVEAADYGGINSDKLFKF HHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCHHCCCCCCCCHHHHH STLIQTWGLIGTAMLLFVAVFLISNTIRMTIMSRKRDIEIMRLVGAKNSYIRGPFFFEGA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECHH WVGLLGAVLPSLLIYYGYDLVYKHFAQELQRNNLSMYPLDPYVYYLIGALFVIGIMIGSL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH GSVLSMRRYLKF HHHHHHHHHHCC >Mature Secondary Structure MVTMIRYFFRHIWESIKNLKRNFWMTFASVSMVAVTLTLVGVFAATLLNIQRVASGVENN CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC VHINTYLQVDSTDAAKVIQNTAGEPVNNDNYHSVYDKIAQIKGVKKITFSSKDEQLKKLQ EEEEEEEEECCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHEECCCHHHHHHHHH ETLGDVWNMYDQDTNPLQDIYLIETQTPKQVKAITKKIRTIEGVEAADYGGINSDKLFKF HHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCHHCCCCCCCCHHHHH STLIQTWGLIGTAMLLFVAVFLISNTIRMTIMSRKRDIEIMRLVGAKNSYIRGPFFFEGA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECHH WVGLLGAVLPSLLIYYGYDLVYKHFAQELQRNNLSMYPLDPYVYYLIGALFVIGIMIGSL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH GSVLSMRRYLKF HHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 7.0
TargetDB status: NA
Availability: NA
References: 9384377 [H]