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The map label for this gene is ccpA [H]

Identifier: 15674618

GI number: 15674618

Start: 413464

End: 414465

Strand: Direct

Name: ccpA [H]

Synonym: SPy_0514

Alternate gene names: 15674618

Gene position: 413464-414465 (Clockwise)

Preceding gene: 15674610

Following gene: 15674619

Centisome position: 22.32

GC content: 40.42

Gene sequence:

>1002_bases
ATGAATACAGATGATCCCCTTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAGTTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGCCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCGGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACCAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Upstream 100 bases:

>100_bases
AACTTTTTCAAAAATTAACCTATAACACTTGAAAGTGGTTACAAATCATGCTAAAATACTTTTTGAAAGCGTCATTTTCA
AATAGAAAGGAAGATAAAAA

Downstream 100 bases:

>100_bases
CTGTGAATTATGAGCACCATCTAACAAAAAGTATCACAATAGACTGTTTCTTCAATACTAAAATCAGCCTTAGGGCTGAT
TTTTGCATGTCTTAGTGAAA

Product: catabolite control protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MNTDDPLTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Sequences:

>Translated_333_residues
MNTDDPLTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK
>Mature_333_residues
MNTDDPLTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes and in the positive regulation of genes involved in excretion of excess carbon [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=329, Percent_Identity=27.6595744680851, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI1790194, Length=331, Percent_Identity=27.7945619335347, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1788474, Length=306, Percent_Identity=29.4117647058824, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1789068, Length=297, Percent_Identity=29.96632996633, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1787948, Length=326, Percent_Identity=26.9938650306748, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1786540, Length=338, Percent_Identity=29.2899408284024, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1787580, Length=314, Percent_Identity=26.4331210191083, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1789202, Length=294, Percent_Identity=28.5714285714286, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790715, Length=316, Percent_Identity=26.8987341772152, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI48994940, Length=309, Percent_Identity=24.2718446601942, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1789456, Length=340, Percent_Identity=25.5882352941176, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1786268, Length=294, Percent_Identity=23.8095238095238, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1787906, Length=328, Percent_Identity=25, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790689, Length=316, Percent_Identity=23.4177215189873, Blast_Score=78, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36710; Mature: 36710

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTDDPLTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLA
CCCCCCEEHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHCC
SKKTTTVGVVIPNIANSYFSILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQ
CCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHH
VDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPSVNIDYRAAVSNVVDILAENH
HCCEEEECHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCC
KCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
CEEEEECCCCEECCCCEEEEEEHHHCCCCCCCCHHCCEEEEECCCHHHHHHHHHHHHHCC
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGA
CCEEEEEHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEECCCCHHHHHHHHHHHHH
VSMRMLTKIMNKEELEEKEILLNHGIKKRGTTK
HHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNTDDPLTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLA
CCCCCCEEHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHCC
SKKTTTVGVVIPNIANSYFSILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQ
CCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCHHHHHHHHHHHH
VDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPSVNIDYRAAVSNVVDILAENH
HCCEEEECHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCC
KCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
CEEEEECCCCEECCCCEEEEEEHHHCCCCCCCCHHCCEEEEECCCHHHHHHHHHHHHHCC
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGA
CCEEEEEHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEECCCCHHHHHHHHHHHHH
VSMRMLTKIMNKEELEEKEILLNHGIKKRGTTK
HHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12397186 [H]