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The map label for this gene is ftsK

Identifier: 15674577

GI number: 15674577

Start: 375224

End: 377629

Strand: Direct

Name: ftsK

Synonym: SPy_0458

Alternate gene names: 15674577

Gene position: 375224-377629 (Clockwise)

Preceding gene: 15674575

Following gene: 15674579

Centisome position: 20.26

GC content: 40.15

Gene sequence:

>2406_bases
ATGGTTAAAAGAAATCAAAGAAAAAAAAGTGCGCCTAAGAAGCGTTTAACAAAAGCAGAAGTGGAAAAGCAACGTGCCAT
TAAGAGGATGATTTTATCTGTTTTAATGGCTTTGTTGCTTATTTTTGCGATGCTTCGCTTGGGCGTCTTTGGTGTGACAA
CTTATAATATGATTCGTTTTTTGGTGGGTAGTTTAGCCTATCCGTTTATGTTTGCCTGGTTAATTTACTTATTTTGTTTT
AAATGGTTACGGCAAAAAGATGGAATGATTGCGGGAGTTGTTATTGCCTTTTTGGGATTGCTAGTTGAGTGGCACGCCTT
CTTATTTGCGATGCCTAGGATGCTTGATCAAGATATTTTTCTAGGCACTGCTCGGCTAATTACAAGAGATTTACTAGCCC
TGCGCGTGACTGAATTTGTTGGTGGAGGAATGCTTGGTGCATTACTTTATAAACCCATAGCCTTTTTATTTTCGAATATC
GGCTCTTACTTTATTGGTTTTTTGTTTATCTTATTAGGATTATTTCTAATGACGCCTTGGGATATCTATGATGTGAGTCA
CTTTGTGAAAGAGGCTGTTGATAAACTAGCAGTGGCTTATCAGGAAAATAAAGAAAAGCGGTTCATCAAACGAGAAGAGC
ACCGCTTACAAGCTGAAAAAGAGGCTTTAGAGAAACAAGCACAAGAGGAAGAAAAACGTCTAGCAGAATTGACGGTTGAT
CCTGAGACGGGAGAGATTGTTGAGGATAGTCAGTCTCAAGTCAGCTATGATTTGGCTGAGGATATGACAAAAGAACCAGA
GATTCTTGCTTATGATAGTCACCTCAAAGACGATGAGACAAGCTTATTTGATCAAGAAGACTTGGCTTACGCTCATGAGG
AAATTGGGGCTTATGACTCTTTATCTGCTTTAGCATCTTCTGAAGATGAGATGGATATGGATGAACCTGTTGAAGTTGAT
TTCACACCAAAAACCCATCTTCTTTATAAACTTCCAACGATAGATTTATTTGCACCAGATAAGCCCAAAAACCAGTCCAA
AGAGAAAAACTTAGTCCGCAAAAATATCAAGGTGCTTGAAGATACCTTCCAAAGTTTTGGGATTGATGTCAAGGTAGAGC
GAGCAGAAATCGGGCCTTCCGTCACCAAATATGAAATCAAGCCAGCTGTCGGGGTCCGAGTTAATCGTATTTCAAATCTT
GCTGATGATTTGGCACTTGCTCTGGCTGCTAAAGATGTTCGTATTGAAGCACCAATTCCTGGAAAATCCTTAATAGGTAT
TGAAGTTCCTAACTCAGAAATTGCAACGGTTTCTTTCCGCGAACTTTGGGAACAATCTGATGCCAATCCTGAAAACCTTT
TAGAAGTACCACTAGGTAAAGCTGTTAATGGCAATGCGCGCAGTTTTAACTTAGCTAGAATGCCGCATCTTTTGGTAGCT
GGTTCAACTGGTTCAGGTAAATCTGTGGCAGTTAATGGCATTATTTCAAGTATTTTGATGAAGGCACGTCCAGATCAAGT
TAAGTTTATGATGATTGACCCCAAAATGGTTGAATTATCTGTTTATAATGATATTCCACATTTATTAATCCCAGTTGTAA
CCAATCCGCGTAAAGCCAGTAAGGCACTCCAAAAAGTGGTTGATGAGATGGAAAACCGCTACGAGTTATTTAGTAAAATT
GGTGTGCGTAATATAGCAGGTTATAATACAAAGGTTGAAGAGTTTAATGCTTCTTCTGAGCAAAAACAAATACCGTTGCC
TTTAATCGTTGTCATTGTAGATGAATTGGCTGACTTGATGATGGTGGCTAGTAAAGAAGTTGAAGATGCTATTATTCGTT
TGGGACAAAAAGCACGTGCTGCAGGTATCCATATGATTCTTGCAACTCAACGTCCCTCTGTAGATGTTATTTCTGGTTTG
ATTAAAGCAAATGTTCCGTCGCGTATGGCATTTGCTGTTTCAAGTGGTACTGATAGCCGTACGATCCTTGATGAAAATGG
TGCTGAAAAGCTCTTGGGACGGGGTGATATGCTCTTTAAGCCGATTGATGAAAATCACCCTGTTCGCTTGCAAGGGTCTT
TCATCTCAGATGATGATGTGGAGCGTATTGTCAACTTTATCAAAGACCAAACTGAAGCGGATTATGATGACGCCTTTGAT
CCTGGTGAAGTTAGCGACAATGATCCTGGTTTTTCTGGAAATGGCGGAGCTGCTGAAGGTGATCCTCTTTTTGAAGAAGC
AAAAGCCTTGGTCTTAGAAACACAAAAAGCTAGTGCCTCAATGATTCAAAGGCGTTTGTCGGTTGGATTTAATCGTGCCA
CGCGCTTGATGGATGAATTGGAAGAAGCAGGTGTTATCGGTCCAGCAGAAGGAACCAAGCCTCGTAAGGTATTGCAGACA
AACTAA

Upstream 100 bases:

>100_bases
CTACGACTGTTATTATAGCACAAGATGCTATAGAAAAACTTAAAACACCTTGGTTTTTTAGAGCTATTTCCTAATAGTTA
AAAAATGGTATAATAGTGTT

Downstream 100 bases:

>100_bases
AAGAACCTGACGTCTCATGATGAGATGTTAGGTTCTTTTTTTGTGATGTCAAGCCAGTTGATGAGATGCCTATGCTAATG
TAAAAATAAAGATAACTAGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 801; Mature: 801

Protein sequence:

>801_residues
MVKRNQRKKSAPKKRLTKAEVEKQRAIKRMILSVLMALLLIFAMLRLGVFGVTTYNMIRFLVGSLAYPFMFAWLIYLFCF
KWLRQKDGMIAGVVIAFLGLLVEWHAFLFAMPRMLDQDIFLGTARLITRDLLALRVTEFVGGGMLGALLYKPIAFLFSNI
GSYFIGFLFILLGLFLMTPWDIYDVSHFVKEAVDKLAVAYQENKEKRFIKREEHRLQAEKEALEKQAQEEEKRLAELTVD
PETGEIVEDSQSQVSYDLAEDMTKEPEILAYDSHLKDDETSLFDQEDLAYAHEEIGAYDSLSALASSEDEMDMDEPVEVD
FTPKTHLLYKLPTIDLFAPDKPKNQSKEKNLVRKNIKVLEDTFQSFGIDVKVERAEIGPSVTKYEIKPAVGVRVNRISNL
ADDLALALAAKDVRIEAPIPGKSLIGIEVPNSEIATVSFRELWEQSDANPENLLEVPLGKAVNGNARSFNLARMPHLLVA
GSTGSGKSVAVNGIISSILMKARPDQVKFMMIDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKI
GVRNIAGYNTKVEEFNASSEQKQIPLPLIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGIHMILATQRPSVDVISGL
IKANVPSRMAFAVSSGTDSRTILDENGAEKLLGRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKDQTEADYDDAFD
PGEVSDNDPGFSGNGGAAEGDPLFEEAKALVLETQKASASMIQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVLQT
N

Sequences:

>Translated_801_residues
MVKRNQRKKSAPKKRLTKAEVEKQRAIKRMILSVLMALLLIFAMLRLGVFGVTTYNMIRFLVGSLAYPFMFAWLIYLFCF
KWLRQKDGMIAGVVIAFLGLLVEWHAFLFAMPRMLDQDIFLGTARLITRDLLALRVTEFVGGGMLGALLYKPIAFLFSNI
GSYFIGFLFILLGLFLMTPWDIYDVSHFVKEAVDKLAVAYQENKEKRFIKREEHRLQAEKEALEKQAQEEEKRLAELTVD
PETGEIVEDSQSQVSYDLAEDMTKEPEILAYDSHLKDDETSLFDQEDLAYAHEEIGAYDSLSALASSEDEMDMDEPVEVD
FTPKTHLLYKLPTIDLFAPDKPKNQSKEKNLVRKNIKVLEDTFQSFGIDVKVERAEIGPSVTKYEIKPAVGVRVNRISNL
ADDLALALAAKDVRIEAPIPGKSLIGIEVPNSEIATVSFRELWEQSDANPENLLEVPLGKAVNGNARSFNLARMPHLLVA
GSTGSGKSVAVNGIISSILMKARPDQVKFMMIDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKI
GVRNIAGYNTKVEEFNASSEQKQIPLPLIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGIHMILATQRPSVDVISGL
IKANVPSRMAFAVSSGTDSRTILDENGAEKLLGRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKDQTEADYDDAFD
PGEVSDNDPGFSGNGGAAEGDPLFEEAKALVLETQKASASMIQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVLQT
N
>Mature_801_residues
MVKRNQRKKSAPKKRLTKAEVEKQRAIKRMILSVLMALLLIFAMLRLGVFGVTTYNMIRFLVGSLAYPFMFAWLIYLFCF
KWLRQKDGMIAGVVIAFLGLLVEWHAFLFAMPRMLDQDIFLGTARLITRDLLALRVTEFVGGGMLGALLYKPIAFLFSNI
GSYFIGFLFILLGLFLMTPWDIYDVSHFVKEAVDKLAVAYQENKEKRFIKREEHRLQAEKEALEKQAQEEEKRLAELTVD
PETGEIVEDSQSQVSYDLAEDMTKEPEILAYDSHLKDDETSLFDQEDLAYAHEEIGAYDSLSALASSEDEMDMDEPVEVD
FTPKTHLLYKLPTIDLFAPDKPKNQSKEKNLVRKNIKVLEDTFQSFGIDVKVERAEIGPSVTKYEIKPAVGVRVNRISNL
ADDLALALAAKDVRIEAPIPGKSLIGIEVPNSEIATVSFRELWEQSDANPENLLEVPLGKAVNGNARSFNLARMPHLLVA
GSTGSGKSVAVNGIISSILMKARPDQVKFMMIDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKI
GVRNIAGYNTKVEEFNASSEQKQIPLPLIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGIHMILATQRPSVDVISGL
IKANVPSRMAFAVSSGTDSRTILDENGAEKLLGRGDMLFKPIDENHPVRLQGSFISDDDVERIVNFIKDQTEADYDDAFD
PGEVSDNDPGFSGNGGAAEGDPLFEEAKALVLETQKASASMIQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVLQT
N

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain

Homologues:

Organism=Escherichia coli, GI1787117, Length=487, Percent_Identity=46.2012320328542, Blast_Score=401, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSK_STRP1 (Q9A155)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_268751.1
- RefSeq:   YP_281735.1
- ProteinModelPortal:   Q9A155
- SMR:   Q9A155
- EnsemblBacteria:   EBSTRT00000001354
- EnsemblBacteria:   EBSTRT00000027700
- GeneID:   3572544
- GeneID:   900700
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_0458
- KEGG:   spz:M5005_Spy_0372
- GeneTree:   EBGT00050000026954
- HOGENOM:   HBG662140
- OMA:   FSNIGSY
- ProtClustDB:   CLSK877051
- BioCyc:   SPYO160490:SPY0458-MONOMER
- BioCyc:   SPYO293653:M5005_SPY0372-MONOMER
- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543
- SMART:   SM00382
- SMART:   SM00843

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE

EC number: NA

Molecular weight: Translated: 89329; Mature: 89329

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc6f71a8)-; HASH(0xc3c86e0)-; HASH(0xc3c8980)-; HASH(0xc88d29c)-; HASH(0xc88a518)-;

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCCCCCCCCCCCHHCCCH
>Mature Secondary Structure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HHCCCCCCCCCCCCCHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11296296