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The map label for this gene is ppaC

Identifier: 15674527

GI number: 15674527

Start: 324879

End: 325814

Strand: Direct

Name: ppaC

Synonym: SPy_0380

Alternate gene names: 15674527

Gene position: 324879-325814 (Clockwise)

Preceding gene: 15674526

Following gene: 15674528

Centisome position: 17.54

GC content: 40.6

Gene sequence:

>936_bases
ATGTCAAAAATTTTAGTTTTTGGTCATCAAAATCCTGATACGGATGCTATTGCATCATCTTATGCTTTTGATTACTTATC
CCAAAAAGCGTTTGGTTTGGATACTGAAGTCGTAGCTTTAGGAACACCTAACGAAGAAACAGCTTTTGCCCTTGATTATT
TTGGTGTTGAGGCACCACGTGTGGTAGAGTCTGCTAAAGCACAAGGGTCTGAACAAGTGATTTTGACAGACCACAATGAA
TTCCAACAATCCATTGCAGATATCCGTGAGGTTGAGGTATATGGTGTGGTTGATCACCACCGTGTGGCTAATTTTGAAAC
TGCAAATCCTTTATACATGCGTGTGGAACCAGTAGGATCAGCCTCATCTATTGTTTACCGTATGTTTAAAGAAAATGGCA
TCGAGGTGCCAAAAGCGATTGCAGGGATGCTCTTGTCTGGTTTGATTTCAGATACCTTGTTGTTGAAATCTCCAACAACT
CATGTGTCTGATCACCTTGTCGCTGAAGAATTGGCAGAGCTGGCAGAAGTGAACTTGGAAGACTATGGAATGGCTCTTTT
AAAAGCAGGTACAAACCTTGCAAGCAAATCAGAAGTAGAATTGATTGGTATTGATGCCAAAACATTTGAATTAAATGGCA
ATGCTGTGCGCGTGGCACAAGTGAACACTGTTGACATTGCAGAAGTCTTAGAACGTCAAGAAGCTATTGAAGCAGCCATT
AAAGATGCCATGGCTGCAGAAGGTTATTCAGATTTTGTTTTGATGATCACGGATATTGTTAACTCAAACTCTGAAATTCT
AGCTATTGGAGCAAACATGGACAAGGTTGAAGCAGCCTTTAACTTCACCCTTGACAACAATCATGCCTTCTTAGCAGGTG
CCGTTTCTCGTAAAAAACAAGTGGTTCCACAATTGACAGAAAGTTTTGGAGCTTAA

Upstream 100 bases:

>100_bases
TTTTTAAAGTATTATAAGCAGATCTTTTGTAATCTTCCTTTGATTTTAGGGGGTAATTTTGCTAAAATAAAATGAATAAA
CAAAATGAGGTAGAATGATT

Downstream 100 bases:

>100_bases
TGAAAAGACGCTTTAAAAGGACTTGATTTTTTTGACCAAGTCCTTTTGTCACTCTTCTATGTTATAATAGAAGGTATGAT
AACAGTATTTCATTCAGATA

Product: putative manganese-dependent inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MSKILVFGHQNPDTDAIASSYAFDYLSQKAFGLDTEVVALGTPNEETAFALDYFGVEAPRVVESAKAQGSEQVILTDHNE
FQQSIADIREVEVYGVVDHHRVANFETANPLYMRVEPVGSASSIVYRMFKENGIEVPKAIAGMLLSGLISDTLLLKSPTT
HVSDHLVAEELAELAEVNLEDYGMALLKAGTNLASKSEVELIGIDAKTFELNGNAVRVAQVNTVDIAEVLERQEAIEAAI
KDAMAAEGYSDFVLMITDIVNSNSEILAIGANMDKVEAAFNFTLDNNHAFLAGAVSRKKQVVPQLTESFGA

Sequences:

>Translated_311_residues
MSKILVFGHQNPDTDAIASSYAFDYLSQKAFGLDTEVVALGTPNEETAFALDYFGVEAPRVVESAKAQGSEQVILTDHNE
FQQSIADIREVEVYGVVDHHRVANFETANPLYMRVEPVGSASSIVYRMFKENGIEVPKAIAGMLLSGLISDTLLLKSPTT
HVSDHLVAEELAELAEVNLEDYGMALLKAGTNLASKSEVELIGIDAKTFELNGNAVRVAQVNTVDIAEVLERQEAIEAAI
KDAMAAEGYSDFVLMITDIVNSNSEILAIGANMDKVEAAFNFTLDNNHAFLAGAVSRKKQVVPQLTESFGA
>Mature_310_residues
SKILVFGHQNPDTDAIASSYAFDYLSQKAFGLDTEVVALGTPNEETAFALDYFGVEAPRVVESAKAQGSEQVILTDHNEF
QQSIADIREVEVYGVVDHHRVANFETANPLYMRVEPVGSASSIVYRMFKENGIEVPKAIAGMLLSGLISDTLLLKSPTTH
VSDHLVAEELAELAEVNLEDYGMALLKAGTNLASKSEVELIGIDAKTFELNGNAVRVAQVNTVDIAEVLERQEAIEAAIK
DAMAAEGYSDFVLMITDIVNSNSEILAIGANMDKVEAAFNFTLDNNHAFLAGAVSRKKQVVPQLTESFGA

Specific function: Unknown

COG id: COG1227

COG function: function code C; Inorganic pyrophosphatase/exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase class C family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPAC_STRP1 (P65757)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_268701.1
- RefSeq:   YP_281683.1
- ProteinModelPortal:   P65757
- SMR:   P65757
- EnsemblBacteria:   EBSTRT00000000293
- EnsemblBacteria:   EBSTRT00000028650
- GeneID:   3572609
- GeneID:   900650
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_0380
- KEGG:   spz:M5005_Spy_0319
- GeneTree:   EBGT00050000027921
- HOGENOM:   HBG541293
- OMA:   CTTADIK
- ProtClustDB:   PRK05427
- BioCyc:   SPYO160490:SPY0380-MONOMER
- BioCyc:   SPYO293653:M5005_SPY0319-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00207
- InterPro:   IPR004097
- InterPro:   IPR022934
- InterPro:   IPR001667

Pfam domain/function: PF01368 DHH; PF02833 DHHA2

EC number: =3.6.1.1

Molecular weight: Translated: 33617; Mature: 33486

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKILVFGHQNPDTDAIASSYAFDYLSQKAFGLDTEVVALGTPNEETAFALDYFGVEAPR
CCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCCHH
VVESAKAQGSEQVILTDHNEFQQSIADIREVEVYGVVDHHRVANFETANPLYMRVEPVGS
HHHHHHCCCCCEEEEECCHHHHHHHHHHHHEEEEEEECCCEECCCCCCCCEEEEEECCCC
ASSIVYRMFKENGIEVPKAIAGMLLSGLISDTLLLKSPTTHVSDHLVAEELAELAEVNLE
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHCCHH
DYGMALLKAGTNLASKSEVELIGIDAKTFELNGNAVRVAQVNTVDIAEVLERQEAIEAAI
HHHHHHHHCCCCCCCCCCEEEEECCEEEEEECCCEEEEEEECCHHHHHHHHHHHHHHHHH
KDAMAAEGYSDFVLMITDIVNSNSEILAIGANMDKVEAAFNFTLDNNHAFLAGAVSRKKQ
HHHHHHCCCCCCEEEEEHHHCCCCCEEEEECCCHHEEEEEEEEECCCCEEEEEHHHHHHH
VVPQLTESFGA
HHHHHHHHHCC
>Mature Secondary Structure 
SKILVFGHQNPDTDAIASSYAFDYLSQKAFGLDTEVVALGTPNEETAFALDYFGVEAPR
CEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCCHH
VVESAKAQGSEQVILTDHNEFQQSIADIREVEVYGVVDHHRVANFETANPLYMRVEPVGS
HHHHHHCCCCCEEEEECCHHHHHHHHHHHHEEEEEEECCCEECCCCCCCCEEEEEECCCC
ASSIVYRMFKENGIEVPKAIAGMLLSGLISDTLLLKSPTTHVSDHLVAEELAELAEVNLE
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHCCHH
DYGMALLKAGTNLASKSEVELIGIDAKTFELNGNAVRVAQVNTVDIAEVLERQEAIEAAI
HHHHHHHHCCCCCCCCCCEEEEECCEEEEEECCCEEEEEEECCHHHHHHHHHHHHHHHHH
KDAMAAEGYSDFVLMITDIVNSNSEILAIGANMDKVEAAFNFTLDNNHAFLAGAVSRKKQ
HHHHHHCCCCCCEEEEEHHHCCCCCEEEEECCCHHEEEEEEEEECCCCEEEEEHHHHHHH
VVPQLTESFGA
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296