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The map label for this gene is glr

Identifier: 15674511

GI number: 15674511

Start: 312519

End: 313313

Strand: Direct

Name: glr

Synonym: SPy_0361

Alternate gene names: 15674511

Gene position: 312519-313313 (Clockwise)

Preceding gene: 15674510

Following gene: 15674512

Centisome position: 16.87

GC content: 40.13

Gene sequence:

>795_bases
ATGGATACAAGACCAATTGGGTTTTTAGATTCTGGTGTGGGAGGTCTGACCGTCGTTTGTGAATTGATTCGTCAGCTCCC
TCATGAGAAGATTGTATATATTGGTGATTCAGCAAGAGCCCCCTATGGTCCTAGACCCAAAAAACAAATTAAGGAGTATA
CTTGGGAGCTAGTCAATTTTTTGCTGACTCAAAATGTTAAAATGATTGTTTTTGCATGCAATACCGCAACAGCGGTGGCT
TGGGAAGAAGTAAAAGCAGCTTTAGATATTCCTGTTTTAGGAGTTGTCTTACCGGGGGCAAGCGCAGCTATTAAATCAAC
GACAAAAGGCCAGGTTGGGGTCATCGGAACCCCAATGACAGTGGCTTCAGACATTTATCGCAAAAAAATCCAGCTATTAG
CACCATCTATTCAAGTAAGGAGTCTTGCTTGCCCGAAGTTTGTACCGATTGTGGAATCAAATGAGATGTGTTCGAGTATA
GCTAAAAAAATAGTTTATGACAGTCTAGCACCATTAGTCGGTAAAATAGATACCCTTGTACTAGGATGTACTCACTATCC
CTTGTTACGACCAATTATCCAAAATGTTATGGGGCCATCTGTTAAGCTGATTGACAGTGGAGCAGAATGCGTCCGAGATA
TCTCTGTCTTATTAAACTATTTTGACATTAACGGTAATTATCATCAAAAAGCTGTCGAACACCGCTTTTTTACAACAGCA
AATCCTGAGATTTTTCAAGAAATTGCCTCGATTTGGCTGAAACAAAAAATAAATGTGGAGCATGTCACCTTATGA

Upstream 100 bases:

>100_bases
TCTTATCAGTTAGATTTGTCAACTGTTCAGGGTTTAAAAAGAAACTCAGTTGGCTATTTCCAACTGAGTTTTTCATATCG
TCAGTAAGGAAGTAAACATA

Downstream 100 bases:

>100_bases
GTGAAAAAATTTACGAATACAAAGATGAAAATAACTGGTTTATCGGAAAGATGACTGGTCATAATTTAATATCGGGCTGG
GGAGTCAAACACACGACAAT

Product: glutamate racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MDTRPIGFLDSGVGGLTVVCELIRQLPHEKIVYIGDSARAPYGPRPKKQIKEYTWELVNFLLTQNVKMIVFACNTATAVA
WEEVKAALDIPVLGVVLPGASAAIKSTTKGQVGVIGTPMTVASDIYRKKIQLLAPSIQVRSLACPKFVPIVESNEMCSSI
AKKIVYDSLAPLVGKIDTLVLGCTHYPLLRPIIQNVMGPSVKLIDSGAECVRDISVLLNYFDINGNYHQKAVEHRFFTTA
NPEIFQEIASIWLKQKINVEHVTL

Sequences:

>Translated_264_residues
MDTRPIGFLDSGVGGLTVVCELIRQLPHEKIVYIGDSARAPYGPRPKKQIKEYTWELVNFLLTQNVKMIVFACNTATAVA
WEEVKAALDIPVLGVVLPGASAAIKSTTKGQVGVIGTPMTVASDIYRKKIQLLAPSIQVRSLACPKFVPIVESNEMCSSI
AKKIVYDSLAPLVGKIDTLVLGCTHYPLLRPIIQNVMGPSVKLIDSGAECVRDISVLLNYFDINGNYHQKAVEHRFFTTA
NPEIFQEIASIWLKQKINVEHVTL
>Mature_264_residues
MDTRPIGFLDSGVGGLTVVCELIRQLPHEKIVYIGDSARAPYGPRPKKQIKEYTWELVNFLLTQNVKMIVFACNTATAVA
WEEVKAALDIPVLGVVLPGASAAIKSTTKGQVGVIGTPMTVASDIYRKKIQLLAPSIQVRSLACPKFVPIVESNEMCSSI
AKKIVYDSLAPLVGKIDTLVLGCTHYPLLRPIIQNVMGPSVKLIDSGAECVRDISVLLNYFDINGNYHQKAVEHRFFTTA
NPEIFQEIASIWLKQKINVEHVTL

Specific function: Provides the (R)-glutamate required for cell wall biosynthesis

COG id: COG0796

COG function: function code M; Glutamate racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate/glutamate racemases family

Homologues:

Organism=Escherichia coli, GI87082355, Length=216, Percent_Identity=31.9444444444444, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURI_STRP1 (Q9A1B7)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_268685.1
- RefSeq:   YP_281667.1
- PDB:   2OHG
- PDB:   2OHO
- PDB:   2OHV
- PDBsum:   2OHG
- PDBsum:   2OHO
- PDBsum:   2OHV
- ProteinModelPortal:   Q9A1B7
- SMR:   Q9A1B7
- EnsemblBacteria:   EBSTRT00000000136
- EnsemblBacteria:   EBSTRT00000027678
- GeneID:   3572593
- GeneID:   900634
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_0361
- KEGG:   spz:M5005_Spy_0303
- GeneTree:   EBGT00050000027649
- HOGENOM:   HBG645102
- OMA:   AILGCTH
- ProtClustDB:   PRK00865
- BioCyc:   SPYO160490:SPY0361-MONOMER
- BioCyc:   SPYO293653:M5005_SPY0303-MONOMER
- HAMAP:   MF_00258
- InterPro:   IPR015942
- InterPro:   IPR001920
- InterPro:   IPR018187
- InterPro:   IPR004391
- Gene3D:   G3DSA:3.40.50.1860
- TIGRFAMs:   TIGR00067

Pfam domain/function: PF01177 Asp_Glu_race; SSF53681 Asp/Glu_race

EC number: =5.1.1.3

Molecular weight: Translated: 29016; Mature: 29016

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: PS00923 ASP_GLU_RACEMASE_1; PS00924 ASP_GLU_RACEMASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTRPIGFLDSGVGGLTVVCELIRQLPHEKIVYIGDSARAPYGPRPKKQIKEYTWELVNF
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
LLTQNVKMIVFACNTATAVAWEEVKAALDIPVLGVVLPGASAAIKSTTKGQVGVIGTPMT
HHHCCCEEEEEEECCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHCCCCCCEEEECCCHH
VASDIYRKKIQLLAPSIQVRSLACPKFVPIVESNEMCSSIAKKIVYDSLAPLVGKIDTLV
HHHHHHHHHHHHHCCCHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGCTHYPLLRPIIQNVMGPSVKLIDSGAECVRDISVLLNYFDINGNYHQKAVEHRFFTTA
CCCCCHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
NPEIFQEIASIWLKQKINVEHVTL
CHHHHHHHHHHHHHHCCCEEEECC
>Mature Secondary Structure
MDTRPIGFLDSGVGGLTVVCELIRQLPHEKIVYIGDSARAPYGPRPKKQIKEYTWELVNF
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
LLTQNVKMIVFACNTATAVAWEEVKAALDIPVLGVVLPGASAAIKSTTKGQVGVIGTPMT
HHHCCCEEEEEEECCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHCCCCCCEEEECCCHH
VASDIYRKKIQLLAPSIQVRSLACPKFVPIVESNEMCSSIAKKIVYDSLAPLVGKIDTLV
HHHHHHHHHHHHHCCCHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGCTHYPLLRPIIQNVMGPSVKLIDSGAECVRDISVLLNYFDINGNYHQKAVEHRFFTTA
CCCCCHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
NPEIFQEIASIWLKQKINVEHVTL
CHHHHHHHHHHHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296