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The map label for this gene is sms

Identifier: 15674421

GI number: 15674421

Start: 205367

End: 206728

Strand: Direct

Name: sms

Synonym: SPy_0236

Alternate gene names: 15674421

Gene position: 205367-206728 (Clockwise)

Preceding gene: 15674420

Following gene: 15674422

Centisome position: 11.09

GC content: 44.64

Gene sequence:

>1362_bases
ATGGCAAAGAAAAAAGCAACCTTTATCTGTCAGGAGTGTGGCTACCAGTCGCCAAAGTATTTAGGGCGCTGTCCAAATTG
CTCGGCCTGGTCTTCTTTTGTGGAAGAAGTAGAGGTCAAAGAAGTCAAAAATGCCCGTGTTAGTCTAGCTGGAGAAAAGT
CCAGACCGGTTAAACTAAAAGATGTGGATAATATTAGTTATCACAGAACACAGACTGACATGTCTGAATTTAATAGAGTT
CTTGGAGGGGGTGTGGTTCCTGGAAGCTTGATTTTAATTGGTGGTGATCCAGGTATTGGAAAATCCACCTTACTCTTGCA
GGTATCCACGCAGCTCGCTAATAAGGGAACGGTTCTCTATGTGTCTGGGGAAGAATCAGCAGAGCAGATTAAACTGCGGA
GTGAGCGTCTGGGTGATATTGACAATGAATTTTACCTCTATGCCGAAACCAATATGCAAGCTATTCGCACAGAAATTGAA
AATATTAAACCAGATTTTTTAATTATTGACTCCATTCAGACCATCATGAGCCCTGATATTACAGGTGTTCAAGGATCAGT
CAGTCAGGTGAGAGAAGTCACTGCAGAATTGATGCAGCTTGCAAAGACGAACAACATTGCAACCTTTATTGTGGGTCATG
TCACCAAGGAAGGAACCTTGGCTGGGCCTCGTATGTTAGAACATATGGTGGATACCGTTCTCTACTTTGAAGGGGAAAGG
CATCACACCTTTCGCATTCTGCGGGCTGTGAAAAACCGCTTTGGCTCCACTAACGAGATTGGCATTTTTGAAATGCAGTC
TGGCGGCTTGGTAGAGGTCTTAAATCCTAGTCAAGTCTTTTTAGAGGAACGCTTAGATGGGGCAACAGGATCGGCTGTCG
TTGTAACGATGGAAGGAAGTCGTCCTATCTTAGCAGAGGTGCAATCTTTAGTGACACCAACCGTTTTTGGCAATGCCAGA
CGAACCACTACGGGACTTGATTTCAATCGCGTAAGCCTAATAATGGCAGTTTTAGAAAAGCGCTGTGGTTTACTCTTACA
AAATCAAGATGCCTACCTCAAGTCGGCTGGTGGTGTCAAACTAGACGAACCTGCCATTGATTTGGCAGTCGCTGTGGCTA
TCGCATCCAGTTATAAGGAAAAACCAACCAGCCCTCAAGAAGCTTTCTTAGGCGAGATCGGGTTAACAGGTGAGATTCGG
CGAGTGACCCGTATTGAGCAACGGATTAATGAAGCAGCAAAGCTTGGCTTTACCAAGGTCTATGCTCCTAAAAATGCCTT
GCAAGGCATTGATATCCCTCAAGGTATTGAGGTTGTCGGAGTGACTACGGTTGGTCAGGTTTTAAATGCAGTTTTTAGCT
AG

Upstream 100 bases:

>100_bases
TTGGTTCGACAGGGCAGTAAAGCGATTTAACAAAAATGCTTATGACAGCAGACCTATTCTTTAAGAGTGGGTTTGTCTTG
TATAGGGGAGGGAGATTACT

Downstream 100 bases:

>100_bases
AGGATCAGAAACTAAGAGCAAATGAGGAGGAAATTTGTCAAGAAAGTATCCCAATCATTTGTTTTTTTAACTTTTCGAAC
GATACCGACCGTCTAAGAGG

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms homolog

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRV
LGGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGTVLYVSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNAR
RTTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIR
RVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLNAVFS

Sequences:

>Translated_453_residues
MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRV
LGGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGTVLYVSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNAR
RTTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIR
RVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLNAVFS
>Mature_452_residues
AKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRVL
GGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGTVLYVSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIEN
IKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGERH
HTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNARR
TTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIRR
VTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLNAVFS

Specific function: May play a role in the repair of endogenous alkylation damage

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily

Homologues:

Organism=Escherichia coli, GI1790850, Length=456, Percent_Identity=41.8859649122807, Blast_Score=368, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RADA_STRP1 (Q9A1K1)

Other databases:

- EMBL:   AE004092
- EMBL:   CP000017
- RefSeq:   NP_268595.1
- RefSeq:   YP_281564.1
- ProteinModelPortal:   Q9A1K1
- SMR:   Q9A1K1
- EnsemblBacteria:   EBSTRT00000000272
- EnsemblBacteria:   EBSTRT00000029096
- GeneID:   3572706
- GeneID:   900541
- GenomeReviews:   AE004092_GR
- GenomeReviews:   CP000017_GR
- KEGG:   spy:SPy_0236
- KEGG:   spz:M5005_Spy_0200
- GeneTree:   EBGT00050000027440
- HOGENOM:   HBG286573
- OMA:   IGVFEMT
- ProtClustDB:   PRK11823
- BioCyc:   SPYO160490:SPY0236-MONOMER
- BioCyc:   SPYO293653:M5005_SPY0200-MONOMER
- GO:   GO:0006508
- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR004504
- InterPro:   IPR008269
- InterPro:   IPR020568
- PRINTS:   PR01874
- SMART:   SM00382
- TIGRFAMs:   TIGR00416

Pfam domain/function: PF06745 KaiC; PF05362 Lon_C; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 49373; Mature: 49242

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLK
CCCCHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCEEEE
DVDNISYHRTQTDMSEFNRVLGGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGTVLY
ECCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEEEHHHCCCCEEEE
VSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIENIKPDFLIIDSIQTIMSPDI
EECCCCHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHCCCCEEEEECHHHHHCCCC
TGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
CCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHEECCCC
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGS
HHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEECCCHHHHHHHHCCCCCCCEEEEEECCC
RPILAEVQSLVTPTVFGNARRTTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVK
CCHHHHHHHHHCCHHCCCCCCEECCCCHHHHHHHHHHHHHHCCEEEECCCHHHHCCCCCE
LDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIRRVTRIEQRINEAAKLGFTKV
ECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEE
YAPKNALQGIDIPQGIEVVGVTTVGQVLNAVFS
ECCCHHHCCCCCCCCCEEEEHHHHHHHHHHHCC
>Mature Secondary Structure 
AKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLK
CCCHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCEEEE
DVDNISYHRTQTDMSEFNRVLGGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGTVLY
ECCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEEEEEEHHHCCCCEEEE
VSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIENIKPDFLIIDSIQTIMSPDI
EECCCCHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHCCCCEEEEECHHHHHCCCC
TGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
CCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHEECCCC
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGS
HHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEECCCHHHHHHHHCCCCCCCEEEEEECCC
RPILAEVQSLVTPTVFGNARRTTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVK
CCHHHHHHHHHCCHHCCCCCCEECCCCHHHHHHHHHHHHHHCCEEEECCCHHHHCCCCCE
LDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIRRVTRIEQRINEAAKLGFTKV
ECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEE
YAPKNALQGIDIPQGIEVVGVTTVGQVLNAVFS
ECCCHHHCCCCCCCCCEEEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11296296