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The map label for this gene is yfkJ [H]

Identifier: 15674281

GI number: 15674281

Start: 54979

End: 55416

Strand: Direct

Name: yfkJ [H]

Synonym: SPy_0039

Alternate gene names: 15674281

Gene position: 54979-55416 (Clockwise)

Preceding gene: 15674280

Following gene: 15674282

Centisome position: 2.97

GC content: 35.62

Gene sequence:

>438_bases
ATGAAAAAAGTATGTTTTGTCTGTCTGGGTAATATTTGTCGAAGCCCCATGGCTGAGTTTGTAATGAAGTCAATAGTATC
AAGTGATGTTATGATGATAGAAAGTCGTGCTACTTCTGATTGGGAGCATGGAAACCCTATTCACTCAGGTACACAGTCCA
TATTAAAAACTTACCAAATTAATTATGATATAACTAAATGCTCCAAGCAGATAACTATAACTGATTTTAACACCTTTGAC
TATATTATTGGTATGGATAGCGATAATGTGAAAAATCTCAAAGAGATGTCGCAACATCAATGGGACTCTAAAATCTACCT
GTTTAGAGAAGGGGGTGTTCCTGATCCTTGGTACACTAACGATTTTGAAGAAACCTACCAATTAGTTAGAAAAGGATGCC
AGGATTGGCTTTCTCGTTTAATGAGTAAAGAGTATTGA

Upstream 100 bases:

>100_bases
TTTTTGTGTTCGGATTTTTTGATAAGTTGACAGAAAATTATTAGATTGATTTCTCCGATATCAGTTAGAAATTTGATATA
ATAATTCAAAGGAGTATTTA

Downstream 100 bases:

>100_bases
TATTAGAAGTTGAGTAAAAGAAATGATAGATATGCAAGATATAGTAAAAAAATGGAGTATTACACGGGCGAAGTTGGAAA
TTGTCTCGGTGATTGTCATA

Product: putative protein-tyrosine phosphatase

Products: NA

Alternate protein names: LMPTP [H]

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MKKVCFVCLGNICRSPMAEFVMKSIVSSDVMMIESRATSDWEHGNPIHSGTQSILKTYQINYDITKCSKQITITDFNTFD
YIIGMDSDNVKNLKEMSQHQWDSKIYLFREGGVPDPWYTNDFEETYQLVRKGCQDWLSRLMSKEY

Sequences:

>Translated_145_residues
MKKVCFVCLGNICRSPMAEFVMKSIVSSDVMMIESRATSDWEHGNPIHSGTQSILKTYQINYDITKCSKQITITDFNTFD
YIIGMDSDNVKNLKEMSQHQWDSKIYLFREGGVPDPWYTNDFEETYQLVRKGCQDWLSRLMSKEY
>Mature_145_residues
MKKVCFVCLGNICRSPMAEFVMKSIVSSDVMMIESRATSDWEHGNPIHSGTQSILKTYQINYDITKCSKQITITDFNTFD
YIIGMDSDNVKNLKEMSQHQWDSKIYLFREGGVPDPWYTNDFEETYQLVRKGCQDWLSRLMSKEY

Specific function: Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=152, Percent_Identity=38.8157894736842, Blast_Score=94, Evalue=4e-20,
Organism=Homo sapiens, GI6005988, Length=152, Percent_Identity=37.5, Blast_Score=88, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6325330, Length=154, Percent_Identity=34.4155844155844, Blast_Score=79, Evalue=2e-16,
Organism=Drosophila melanogaster, GI78706766, Length=156, Percent_Identity=31.4102564102564, Blast_Score=79, Evalue=8e-16,
Organism=Drosophila melanogaster, GI78706768, Length=156, Percent_Identity=31.4102564102564, Blast_Score=79, Evalue=8e-16,
Organism=Drosophila melanogaster, GI78706770, Length=155, Percent_Identity=29.0322580645161, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI78706772, Length=155, Percent_Identity=29.0322580645161, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI78706764, Length=132, Percent_Identity=32.5757575757576, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI78711846, Length=151, Percent_Identity=29.1390728476821, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 16952; Mature: 16952

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
9.0 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
9.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVCFVCLGNICRSPMAEFVMKSIVSSDVMMIESRATSDWEHGNPIHSGTQSILKTYQI
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHC
NYDITKCSKQITITDFNTFDYIIGMDSDNVKNLKEMSQHQWDSKIYLFREGGVPDPWYTN
CCCHHHCCCEEEEEECCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCC
DFEETYQLVRKGCQDWLSRLMSKEY
CHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKVCFVCLGNICRSPMAEFVMKSIVSSDVMMIESRATSDWEHGNPIHSGTQSILKTYQI
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHC
NYDITKCSKQITITDFNTFDYIIGMDSDNVKNLKEMSQHQWDSKIYLFREGGVPDPWYTN
CCCHHHCCCEEEEEECCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCC
DFEETYQLVRKGCQDWLSRLMSKEY
CHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]