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The map label for this gene is dinF [H]

Identifier: 13474727

GI number: 13474727

Start: 4566909

End: 4568324

Strand: Direct

Name: dinF [H]

Synonym: mlr5680

Alternate gene names: 13474727

Gene position: 4566909-4568324 (Clockwise)

Preceding gene: 13474725

Following gene: 13474730

Centisome position: 64.91

GC content: 65.75

Gene sequence:

>1416_bases
ATGATTGCACGGTGGCCGGAAAATGGGGCACATCGGCTGTACGATCAAGCCGCAAATCAGCAAGGCAGCAATCCCTTGGA
CAAGGGTGCAACTCCAGTCGACGCCAGATCTTTTGTCGTCACCAACCGCTCCGTGCTCGCCATAGCGGTGCCGATGACGC
TCGCCTATCTGACCACGCCGATGCTCGGCCTGGTCGACACGGCTGTTGTCGGCCAGTTCGGCGACGCGGCTCTTCTCGGC
GGCCTTGCGGCGGGCGCGCTTGTTTTCGACGTCGTCTTCACCAGCTTCAATTTCCTGCGTTCGGGCACCACCGGCCTCGT
CGCCCAGGCTTTCGGGCGTGGCGACACGCTCGAGGAACAGGCGGTGTTCTGGCGCGCCGTGCTGATCGCGGTCGTTGCCG
GTATCGTGCTGGCCGCACTTTCGCCGCTGATCGCCATCGGCGGCCAGTGGTTCATGGGCGCCGAACCGCGTGTCAGCGAG
GCGATGGGCGTCTACATCAGGATCAGGCTACTTGCCGCACCGTTCTCGCTGATCAACTACGCCATTCTCGGCTACGTCCT
GGGCCGTGGCGAGGGCGGGCTCGGCCTTGTGCTGCAACTGGTGCTCAACGGCATCAACATCGCGCTCTGCTTCCTGCTTG
GCCTTGAGCTTGGCTGGGGCGTTGCCGGCGTCGCCTGGGCGACCGTCACGGGCGAATTCCTGGCCATGCTGCTGGGTCTC
GCCATCGTGGTTCGCCGCTTCCGCGCGACCCCGCCCTTGCCGCGCCATCGGCTGCTCGACATGGCCGCCTTCCTGCGCAT
GCTGTCGCTCAATCGCGACATCATGATCCGCTCGTTCTCGCTGCTTGCCGCTTTCGCACTGTTCACCCGCCAGGGCGCGC
AGTTCGGCACGGTGACGCTGGCTGCCAATGCGGTGTTGATGAACTTCTTCCTGGTCGCCGGCTATTTCCTCGACGGTTTT
GCCACCGCGGCCGAACAGCTCGCGGGCCGCGCCGTCGGCGCGCGCGCCGAACAGCCCTTCCGGCAGGCGGTGCGGCTGAC
CCTGTTCTGGGGATTAGGGCTGGCCGGCGCCGCGACCCTGGTGCTCTTGTCGGCAGGCGCCAATCTGGTCGCCATCGTCA
CGACGTCGCAAGAGGTGCGCTCCGTGGCCGACATCTATTTGCCTTGGGCGGCGTTCACCGCGCTGAGCGGCGTGCTGGCG
TTCCAGATGGATGGCGTCTTCATCGGCGCGACCTGGTCGCGCGACATGCGCAACATGATGTTGCTGTCGTTCCTGGTCTT
TGCCGTCGCGCTGCTGACGTTGGCGCCTGCCTTCGGCAATCACGGCCTGTGGGCGGCGCTGCACGTTTTCCTGCTGGCGC
GCGGCTTCAGCCTGCTGACGATTTTGCGGCTGCGGGTGCGGACGGCGTTCAGCTGA

Upstream 100 bases:

>100_bases
GCCGGCGTCGTAGTCGGGGTGGTGGACGATCTGCAGGGGCATGAACGGGATCCGGCGGCTTCGCGCCAGACCGGGATTTC
GGTTGGCCATCGCGGGAAGA

Downstream 100 bases:

>100_bases
GTGGCTTGGACGCCCACCGATCGAGGTGGCTGTCGCGCAATTCGCCAATGGACTTCAGTCGCTCCGTCTCGCAAAAGCGT
GCCATGCCGGCGACGATACG

Product: DNA-damage-inducible protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MIARWPENGAHRLYDQAANQQGSNPLDKGATPVDARSFVVTNRSVLAIAVPMTLAYLTTPMLGLVDTAVVGQFGDAALLG
GLAAGALVFDVVFTSFNFLRSGTTGLVAQAFGRGDTLEEQAVFWRAVLIAVVAGIVLAALSPLIAIGGQWFMGAEPRVSE
AMGVYIRIRLLAAPFSLINYAILGYVLGRGEGGLGLVLQLVLNGINIALCFLLGLELGWGVAGVAWATVTGEFLAMLLGL
AIVVRRFRATPPLPRHRLLDMAAFLRMLSLNRDIMIRSFSLLAAFALFTRQGAQFGTVTLAANAVLMNFFLVAGYFLDGF
ATAAEQLAGRAVGARAEQPFRQAVRLTLFWGLGLAGAATLVLLSAGANLVAIVTTSQEVRSVADIYLPWAAFTALSGVLA
FQMDGVFIGATWSRDMRNMMLLSFLVFAVALLTLAPAFGNHGLWAALHVFLLARGFSLLTILRLRVRTAFS

Sequences:

>Translated_471_residues
MIARWPENGAHRLYDQAANQQGSNPLDKGATPVDARSFVVTNRSVLAIAVPMTLAYLTTPMLGLVDTAVVGQFGDAALLG
GLAAGALVFDVVFTSFNFLRSGTTGLVAQAFGRGDTLEEQAVFWRAVLIAVVAGIVLAALSPLIAIGGQWFMGAEPRVSE
AMGVYIRIRLLAAPFSLINYAILGYVLGRGEGGLGLVLQLVLNGINIALCFLLGLELGWGVAGVAWATVTGEFLAMLLGL
AIVVRRFRATPPLPRHRLLDMAAFLRMLSLNRDIMIRSFSLLAAFALFTRQGAQFGTVTLAANAVLMNFFLVAGYFLDGF
ATAAEQLAGRAVGARAEQPFRQAVRLTLFWGLGLAGAATLVLLSAGANLVAIVTTSQEVRSVADIYLPWAAFTALSGVLA
FQMDGVFIGATWSRDMRNMMLLSFLVFAVALLTLAPAFGNHGLWAALHVFLLARGFSLLTILRLRVRTAFS
>Mature_471_residues
MIARWPENGAHRLYDQAANQQGSNPLDKGATPVDARSFVVTNRSVLAIAVPMTLAYLTTPMLGLVDTAVVGQFGDAALLG
GLAAGALVFDVVFTSFNFLRSGTTGLVAQAFGRGDTLEEQAVFWRAVLIAVVAGIVLAALSPLIAIGGQWFMGAEPRVSE
AMGVYIRIRLLAAPFSLINYAILGYVLGRGEGGLGLVLQLVLNGINIALCFLLGLELGWGVAGVAWATVTGEFLAMLLGL
AIVVRRFRATPPLPRHRLLDMAAFLRMLSLNRDIMIRSFSLLAAFALFTRQGAQFGTVTLAANAVLMNFFLVAGYFLDGF
ATAAEQLAGRAVGARAEQPFRQAVRLTLFWGLGLAGAATLVLLSAGANLVAIVTTSQEVRSVADIYLPWAAFTALSGVLA
FQMDGVFIGATWSRDMRNMMLLSFLVFAVALLTLAPAFGNHGLWAALHVFLLARGFSLLTILRLRVRTAFS

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790477, Length=431, Percent_Identity=36.4269141531323, Blast_Score=194, Evalue=9e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 50185; Mature: 50185

Theoretical pI: Translated: 10.58; Mature: 10.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIARWPENGAHRLYDQAANQQGSNPLDKGATPVDARSFVVTNRSVLAIAVPMTLAYLTTP
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCEEEHHHHHHHHHHHHH
MLGLVDTAVVGQFGDAALLGGLAAGALVFDVVFTSFNFLRSGTTGLVAQAFGRGDTLEEQ
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHH
AVFWRAVLIAVVAGIVLAALSPLIAIGGQWFMGAEPRVSEAMGVYIRIRLLAAPFSLINY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AILGYVLGRGEGGLGLVLQLVLNGINIALCFLLGLELGWGVAGVAWATVTGEFLAMLLGL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
AIVVRRFRATPPLPRHRLLDMAAFLRMLSLNRDIMIRSFSLLAAFALFTRQGAQFGTVTL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHH
AANAVLMNFFLVAGYFLDGFATAAEQLAGRAVGARAEQPFRQAVRLTLFWGLGLAGAATL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHH
VLLSAGANLVAIVTTSQEVRSVADIYLPWAAFTALSGVLAFQMDGVFIGATWSRDMRNMM
HHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHEEECCEEEECCCHHHHHHHH
LLSFLVFAVALLTLAPAFGNHGLWAALHVFLLARGFSLLTILRLRVRTAFS
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIARWPENGAHRLYDQAANQQGSNPLDKGATPVDARSFVVTNRSVLAIAVPMTLAYLTTP
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCEEEHHHHHHHHHHHHH
MLGLVDTAVVGQFGDAALLGGLAAGALVFDVVFTSFNFLRSGTTGLVAQAFGRGDTLEEQ
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHH
AVFWRAVLIAVVAGIVLAALSPLIAIGGQWFMGAEPRVSEAMGVYIRIRLLAAPFSLINY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AILGYVLGRGEGGLGLVLQLVLNGINIALCFLLGLELGWGVAGVAWATVTGEFLAMLLGL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
AIVVRRFRATPPLPRHRLLDMAAFLRMLSLNRDIMIRSFSLLAAFALFTRQGAQFGTVTL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHH
AANAVLMNFFLVAGYFLDGFATAAEQLAGRAVGARAEQPFRQAVRLTLFWGLGLAGAATL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHH
VLLSAGANLVAIVTTSQEVRSVADIYLPWAAFTALSGVLAFQMDGVFIGATWSRDMRNMM
HHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHEEECCEEEECCCHHHHHHHH
LLSFLVFAVALLTLAPAFGNHGLWAALHVFLLARGFSLLTILRLRVRTAFS
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]