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The map label for this gene is mocR [H]

Identifier: 13474511

GI number: 13474511

Start: 4325605

End: 4327098

Strand: Reverse

Name: mocR [H]

Synonym: mll5410

Alternate gene names: 13474511

Gene position: 4327098-4325605 (Counterclockwise)

Preceding gene: 13474514

Following gene: 13474510

Centisome position: 61.5

GC content: 66.13

Gene sequence:

>1494_bases
ATGCCACAGCGCAACGACACGGCCATATGGTCCGGCCTGTTCCGGATTTCGGCCGAATCCGGCCAAACCCTGCAGGCGCA
GATCCGCCAGGCCATCGTGGCCGCCATTCTCGACCGGCAGATCGCCGCTTCGATGCCGCTTCCCTCCTGCCGCATCCTGG
CTGAAAAACTAGGCGTCGCACGCGGGACGGTGGTTCTGGCCTTCCAGCAGCTCGTCGACCAGGGGTTCCTGGTGGCGCGC
GAGCGGCGCGGCCATTTCGTCAATCCCGACGTGCTGGCAACACCGGCCAAGCCGCACCAGAAGGCGCCCGACCAGGCCAA
TGAGATCGACTGGAAGGCGCGTCGGCAGATCGCCGCCAGCGACATGCCGCCGCCGGCCAAGCACGAGAACTGGATCAAGT
CGTCCTACCCGTTCGTCTACGGCCAGTTCGACCCGGCGCTGTTCCCGACCGCCGAATGGCGCGAGTGCAACCGCATGGCG
CTGGCGGTGCTCGAAATCCGCAACTGGGCGTCCGACATGGTCGATCGCGACGATCCGCTGCTGATCGAGCAGATCCAGGC
GCGGCTCTTGCCCCGGCGTGGCATCTTCGCCAATCCCGACGAGATCATCGTCACGCTGGGCGCCCAGAACGCGCTCTACA
TGCTGGCTTCGCTGCTGATGACCAAGGGCTCGAAGGTGGCGATGGAAGATCCGGGCTACCCCGACGCACGCTCGATCTTC
CGGCTTGCGGGCGCCGACATCCAGCCGGTGCCGGTCGACCAGTCCGGCATCGTAACCTCTTCTATCCCCAATGATTCCGG
CTTCGTCTTCGTCACTCCGAGCCACCATTGCCCGACCATGGTGCCGTTGTCGGCCGAGCGGCGGCAGGATCTTCTGGCGC
GCGCCAACCGGCACAACCAGATCATCATCGAGGACGGCTATGACAGCCAGCTTCTCGACGAGGCGCCGCAGCAGGCGCTG
AAGAGCCTCGATCGTTCCGGCCGCGTCGTCTATGTCGGCTCGATGTCGAAGACGCTGGCTCCCGGTCTGCGACTTGGCTA
CATCGTCGCCTCGGCTGGACTAATCTCGGAGCTGAGGGCCTTGCGCCGCTTCATGCTGCGCCATCCGCCGGCCAACAACC
AGCGTGCCGTGGCGCTGTTCCTGTCGCTCGGCCATCACGAGGCATTGGTGCGGCGTCTGTCGAGCGCCTTCGACGAGCGG
CGCAAGCGTCTGGTCCATGCGATTTCCGCTTTCCTGCCGGAATGGCGCTCGACCGACTCTGCTGGCGGCACGTCGCTCTG
GCTCGAAGGTCCGCGCGGCACGGATTCCCGCGGATTGGCCGAGGCCGCGGCCTCGCGCAGCGTGATCATCGAGCCGGGAG
ACCGCTTCTTCGACCGCACCGAAAAGCCTTCGCGTTTCATGCGGTTGGGCATTTCCTCGATCGCGCTGCAGCATATCGAG
CCAGGCATCCGGGAACTGGCCACCGCTGCCGGACGCAGGCCTGCCGCCGCCTGA

Upstream 100 bases:

>100_bases
CAAAGATCAGAAAAATTGATTGGCGCAACCCCTTGTGCCACCCATACACTCGACTGGTCCAGCCAAATGAAAATGGCTGG
CCATCCGAGGAAGATTTCCC

Downstream 100 bases:

>100_bases
TCCACTTACCCGATCTGTTGAACGGAGCCGCACAATCGCGGCTCCGTTTCCTTTAGCGCTGGCATATGCAACCACACCGA
CTGGCCCATGGTCTGTGCCA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 497; Mature: 496

Protein sequence:

>497_residues
MPQRNDTAIWSGLFRISAESGQTLQAQIRQAIVAAILDRQIAASMPLPSCRILAEKLGVARGTVVLAFQQLVDQGFLVAR
ERRGHFVNPDVLATPAKPHQKAPDQANEIDWKARRQIAASDMPPPAKHENWIKSSYPFVYGQFDPALFPTAEWRECNRMA
LAVLEIRNWASDMVDRDDPLLIEQIQARLLPRRGIFANPDEIIVTLGAQNALYMLASLLMTKGSKVAMEDPGYPDARSIF
RLAGADIQPVPVDQSGIVTSSIPNDSGFVFVTPSHHCPTMVPLSAERRQDLLARANRHNQIIIEDGYDSQLLDEAPQQAL
KSLDRSGRVVYVGSMSKTLAPGLRLGYIVASAGLISELRALRRFMLRHPPANNQRAVALFLSLGHHEALVRRLSSAFDER
RKRLVHAISAFLPEWRSTDSAGGTSLWLEGPRGTDSRGLAEAAASRSVIIEPGDRFFDRTEKPSRFMRLGISSIALQHIE
PGIRELATAAGRRPAAA

Sequences:

>Translated_497_residues
MPQRNDTAIWSGLFRISAESGQTLQAQIRQAIVAAILDRQIAASMPLPSCRILAEKLGVARGTVVLAFQQLVDQGFLVAR
ERRGHFVNPDVLATPAKPHQKAPDQANEIDWKARRQIAASDMPPPAKHENWIKSSYPFVYGQFDPALFPTAEWRECNRMA
LAVLEIRNWASDMVDRDDPLLIEQIQARLLPRRGIFANPDEIIVTLGAQNALYMLASLLMTKGSKVAMEDPGYPDARSIF
RLAGADIQPVPVDQSGIVTSSIPNDSGFVFVTPSHHCPTMVPLSAERRQDLLARANRHNQIIIEDGYDSQLLDEAPQQAL
KSLDRSGRVVYVGSMSKTLAPGLRLGYIVASAGLISELRALRRFMLRHPPANNQRAVALFLSLGHHEALVRRLSSAFDER
RKRLVHAISAFLPEWRSTDSAGGTSLWLEGPRGTDSRGLAEAAASRSVIIEPGDRFFDRTEKPSRFMRLGISSIALQHIE
PGIRELATAAGRRPAAA
>Mature_496_residues
PQRNDTAIWSGLFRISAESGQTLQAQIRQAIVAAILDRQIAASMPLPSCRILAEKLGVARGTVVLAFQQLVDQGFLVARE
RRGHFVNPDVLATPAKPHQKAPDQANEIDWKARRQIAASDMPPPAKHENWIKSSYPFVYGQFDPALFPTAEWRECNRMAL
AVLEIRNWASDMVDRDDPLLIEQIQARLLPRRGIFANPDEIIVTLGAQNALYMLASLLMTKGSKVAMEDPGYPDARSIFR
LAGADIQPVPVDQSGIVTSSIPNDSGFVFVTPSHHCPTMVPLSAERRQDLLARANRHNQIIIEDGYDSQLLDEAPQQALK
SLDRSGRVVYVGSMSKTLAPGLRLGYIVASAGLISELRALRRFMLRHPPANNQRAVALFLSLGHHEALVRRLSSAFDERR
KRLVHAISAFLPEWRSTDSAGGTSLWLEGPRGTDSRGLAEAAASRSVIIEPGDRFFDRTEKPSRFMRLGISSIALQHIEP
GIRELATAAGRRPAAA

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=311, Percent_Identity=24.7588424437299, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI33469970, Length=311, Percent_Identity=24.7588424437299, Blast_Score=99, Evalue=7e-21,
Organism=Escherichia coli, GI1787710, Length=504, Percent_Identity=28.7698412698413, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1790797, Length=424, Percent_Identity=27.3584905660377, Blast_Score=114, Evalue=1e-26,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 54852; Mature: 54720

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQRNDTAIWSGLFRISAESGQTLQAQIRQAIVAAILDRQIAASMPLPSCRILAEKLGVA
CCCCCCHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
RGTVVLAFQQLVDQGFLVARERRGHFVNPDVLATPAKPHQKAPDQANEIDWKARRQIAAS
CHHHHHHHHHHHHCCCEEEHHCCCCCCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHC
DMPPPAKHENWIKSSYPFVYGQFDPALFPTAEWRECNRMALAVLEIRNWASDMVDRDDPL
CCCCCCCCCCHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
LIEQIQARLLPRRGIFANPDEIIVTLGAQNALYMLASLLMTKGSKVAMEDPGYPDARSIF
HHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCEEEECCCCCCCHHHHH
RLAGADIQPVPVDQSGIVTSSIPNDSGFVFVTPSHHCPTMVPLSAERRQDLLARANRHNQ
HHHCCCCCCCCCCCCCCEEECCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCE
IIIEDGYDSQLLDEAPQQALKSLDRSGRVVYVGSMSKTLAPGLRLGYIVASAGLISELRA
EEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHCCCHHHHHHHHHHHHHHHHHH
LRRFMLRHPPANNQRAVALFLSLGHHEALVRRLSSAFDERRKRLVHAISAFLPEWRSTDS
HHHHHHHCCCCCCCCEEEEEEHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCC
AGGTSLWLEGPRGTDSRGLAEAAASRSVIIEPGDRFFDRTEKPSRFMRLGISSIALQHIE
CCCCEEEEECCCCCCCCHHHHHHCCCCEEECCCHHHHCCCCCHHHHHHHHHHHHHHHHHC
PGIRELATAAGRRPAAA
HHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PQRNDTAIWSGLFRISAESGQTLQAQIRQAIVAAILDRQIAASMPLPSCRILAEKLGVA
CCCCCHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
RGTVVLAFQQLVDQGFLVARERRGHFVNPDVLATPAKPHQKAPDQANEIDWKARRQIAAS
CHHHHHHHHHHHHCCCEEEHHCCCCCCCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHC
DMPPPAKHENWIKSSYPFVYGQFDPALFPTAEWRECNRMALAVLEIRNWASDMVDRDDPL
CCCCCCCCCCHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
LIEQIQARLLPRRGIFANPDEIIVTLGAQNALYMLASLLMTKGSKVAMEDPGYPDARSIF
HHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCEEEECCCCCCCHHHHH
RLAGADIQPVPVDQSGIVTSSIPNDSGFVFVTPSHHCPTMVPLSAERRQDLLARANRHNQ
HHHCCCCCCCCCCCCCCEEECCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCE
IIIEDGYDSQLLDEAPQQALKSLDRSGRVVYVGSMSKTLAPGLRLGYIVASAGLISELRA
EEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHCCCHHHHHHHHHHHHHHHHHH
LRRFMLRHPPANNQRAVALFLSLGHHEALVRRLSSAFDERRKRLVHAISAFLPEWRSTDS
HHHHHHHCCCCCCCCEEEEEEHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCC
AGGTSLWLEGPRGTDSRGLAEAAASRSVIIEPGDRFFDRTEKPSRFMRLGISSIALQHIE
CCCCEEEEECCCCCCCCHHHHHHCCCCEEECCCHHHHCCCCCHHHHHHHHHHHHHHHHHC
PGIRELATAAGRRPAAA
HHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]