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The map label for this gene is hcr [H]

Identifier: 13474254

GI number: 13474254

Start: 4041916

End: 4043013

Strand: Reverse

Name: hcr [H]

Synonym: mll5100

Alternate gene names: 13474254

Gene position: 4043013-4041916 (Counterclockwise)

Preceding gene: 13474255

Following gene: 13474249

Centisome position: 57.46

GC content: 65.3

Gene sequence:

>1098_bases
ATGACGGATCTTGGCCTCTATCGCCATCTCGACCAGATGGCGCCCTGGAACGACAGGCTGCAGGTGCTGGAAGTGATCGG
CGTCAGCGACGAGGCGCCTGACGTCAAGACCTTCACCTTCCGCTCCGACAACCAGACCTGGTTCCGCTACAAGCCGGGAC
AGTTCGTGACGCTGGAACTGCCGACGCCGGACGGGCCGCTGATGCGCACCTATACGCTGTCGTCGTCGCCGTCTCGGCCG
TTCTCGATCGCGGTGACGGTGAAGGCGCAGGCCGGCAGCATCGGCACGCGCTGGATGTTCGATCACCTGGTGCCCGGTTC
GCACGTCAAGGCCTATGGGCCGAGCGGCGACTTTTCGCTGCACAGCCATCCGGCGGCCAAATATCTGTTCATCTCGGCCG
GCTCCGGCGTGACGCCGATGATGTCGATGCTGCGCTGGTTGAACGATTGCGCGCCATGGACCGATGTCGGCTTCGTCAAC
TGCGCGCGGCGCCCGGAAGAGATCATCTTCCGCAAGGAGCTCGAACTGCTCGGCGGCCATATGCCGGGCCTGTCGCTCGG
ATTCATGATCGAGGAGCGGTCGAGCCGCGAGGGCTGGTACGGCCATATGGGCCGCATCGACGCGATCCGGTTGCCGCTGC
TGGCGCCCGATTTCCGCGAACGCGAGATCTTCTGCTGCGGGCCGGACCCTTTCATGCGCGCCGTGCGCGGCATGCTGGAA
GCCGCCGGCTTCGACATGACGAAATACCACCAGGAGAGCTTTGCCGCACCCGCGGTGGAGGAAGTTCCGGCGCCGTTCGT
GTCGCCCGGTGAAGACGGCGTGACCGTCCCCGTCGAAGCGACACCGATCCGCTTCGCGCTTTCGGTTGTCGATGCCGAAT
GCGTCGCCGGCCAGACCGTGCTGCAGACGGCGCGCGCCTCCGGGGTGCGGATCCCCGCGGCCTGCGAATTCGGCCTATGC
GGGACCTGCAAGGTGAAGAAAGTCTCCGGCGCCGTCGAGATGAGCCACAATGGCGGCATCCTCGACCACGAGATCGATGA
CGGCTTCATCCTAGCCTGCTGCTCGAAGCCGCTTTCGGCTCTCGAAATCGAGGCGTAG

Upstream 100 bases:

>100_bases
AGTTCGTCGACTGGTATGCCCGCTTCATCGGTCCGCGCCTTGCCGGAGATGGCCGGCCGGCGTTGCGCAGCGTTGCTTGA
GAGGTTGAGGGATGAATGCG

Downstream 100 bases:

>100_bases
CAGCGTCGGGCGGCCCCTGTACGGCGCGGCCTTGCCAAGCAATTGCGGCTGTTTCCAAGATCCTGGCGGCTCGGTAGGGA
CGCGCGTCAGGATCGGCTTG

Product: ferredoxin [2Fe-2S] I

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MTDLGLYRHLDQMAPWNDRLQVLEVIGVSDEAPDVKTFTFRSDNQTWFRYKPGQFVTLELPTPDGPLMRTYTLSSSPSRP
FSIAVTVKAQAGSIGTRWMFDHLVPGSHVKAYGPSGDFSLHSHPAAKYLFISAGSGVTPMMSMLRWLNDCAPWTDVGFVN
CARRPEEIIFRKELELLGGHMPGLSLGFMIEERSSREGWYGHMGRIDAIRLPLLAPDFREREIFCCGPDPFMRAVRGMLE
AAGFDMTKYHQESFAAPAVEEVPAPFVSPGEDGVTVPVEATPIRFALSVVDAECVAGQTVLQTARASGVRIPAACEFGLC
GTCKVKKVSGAVEMSHNGGILDHEIDDGFILACCSKPLSALEIEA

Sequences:

>Translated_365_residues
MTDLGLYRHLDQMAPWNDRLQVLEVIGVSDEAPDVKTFTFRSDNQTWFRYKPGQFVTLELPTPDGPLMRTYTLSSSPSRP
FSIAVTVKAQAGSIGTRWMFDHLVPGSHVKAYGPSGDFSLHSHPAAKYLFISAGSGVTPMMSMLRWLNDCAPWTDVGFVN
CARRPEEIIFRKELELLGGHMPGLSLGFMIEERSSREGWYGHMGRIDAIRLPLLAPDFREREIFCCGPDPFMRAVRGMLE
AAGFDMTKYHQESFAAPAVEEVPAPFVSPGEDGVTVPVEATPIRFALSVVDAECVAGQTVLQTARASGVRIPAACEFGLC
GTCKVKKVSGAVEMSHNGGILDHEIDDGFILACCSKPLSALEIEA
>Mature_364_residues
TDLGLYRHLDQMAPWNDRLQVLEVIGVSDEAPDVKTFTFRSDNQTWFRYKPGQFVTLELPTPDGPLMRTYTLSSSPSRPF
SIAVTVKAQAGSIGTRWMFDHLVPGSHVKAYGPSGDFSLHSHPAAKYLFISAGSGVTPMMSMLRWLNDCAPWTDVGFVNC
ARRPEEIIFRKELELLGGHMPGLSLGFMIEERSSREGWYGHMGRIDAIRLPLLAPDFREREIFCCGPDPFMRAVRGMLEA
AGFDMTKYHQESFAAPAVEEVPAPFVSPGEDGVTVPVEATPIRFALSVVDAECVAGQTVLQTARASGVRIPAACEFGLCG
TCKVKKVSGAVEMSHNGGILDHEIDDGFILACCSKPLSALEIEA

Specific function: NADH oxidoreductase acting in concert with HCP [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1787098, Length=348, Percent_Identity=29.3103448275862, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1787658, Length=346, Percent_Identity=28.9017341040462, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1788104, Length=339, Percent_Identity=24.188790560472, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788903, Length=212, Percent_Identity=27.3584905660377, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR000951
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 39991; Mature: 39860

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLGLYRHLDQMAPWNDRLQVLEVIGVSDEAPDVKTFTFRSDNQTWFRYKPGQFVTLEL
CCCHHHHHHHHHCCCCCHHHEEEEEECCCCCCCCCEEEEEECCCCEEEEECCCCEEEEEE
PTPDGPLMRTYTLSSSPSRPFSIAVTVKAQAGSIGTRWMFDHLVPGSHVKAYGPSGDFSL
CCCCCCEEEEEEECCCCCCCEEEEEEEEECCCCCCCHHHHHHCCCCCCEEEECCCCCCCC
HSHPAAKYLFISAGSGVTPMMSMLRWLNDCAPWTDVGFVNCARRPEEIIFRKELELLGGH
CCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHHHHCCC
MPGLSLGFMIEERSSREGWYGHMGRIDAIRLPLLAPDFREREIFCCGPDPFMRAVRGMLE
CCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHH
AAGFDMTKYHQESFAAPAVEEVPAPFVSPGEDGVTVPVEATPIRFALSVVDAECVAGQTV
HCCCCHHHHHHHHHCCCCHHHCCCCCCCCCCCCEEEEEECCCCEEEEEEHHHHHHCCHHH
LQTARASGVRIPAACEFGLCGTCKVKKVSGAVEMSHNGGILDHEIDDGFILACCSKPLSA
HHHHHHCCCCCCCEECCCCCCCEEEEEECCEEEECCCCCEEEEECCCCEEEEECCCCCCC
LEIEA
EEECC
>Mature Secondary Structure 
TDLGLYRHLDQMAPWNDRLQVLEVIGVSDEAPDVKTFTFRSDNQTWFRYKPGQFVTLEL
CCHHHHHHHHHCCCCCHHHEEEEEECCCCCCCCCEEEEEECCCCEEEEECCCCEEEEEE
PTPDGPLMRTYTLSSSPSRPFSIAVTVKAQAGSIGTRWMFDHLVPGSHVKAYGPSGDFSL
CCCCCCEEEEEEECCCCCCCEEEEEEEEECCCCCCCHHHHHHCCCCCCEEEECCCCCCCC
HSHPAAKYLFISAGSGVTPMMSMLRWLNDCAPWTDVGFVNCARRPEEIIFRKELELLGGH
CCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHHHHCCC
MPGLSLGFMIEERSSREGWYGHMGRIDAIRLPLLAPDFREREIFCCGPDPFMRAVRGMLE
CCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHHH
AAGFDMTKYHQESFAAPAVEEVPAPFVSPGEDGVTVPVEATPIRFALSVVDAECVAGQTV
HCCCCHHHHHHHHHCCCCHHHCCCCCCCCCCCCEEEEEECCCCEEEEEEHHHHHHCCHHH
LQTARASGVRIPAACEFGLCGTCKVKKVSGAVEMSHNGGILDHEIDDGFILACCSKPLSA
HHHHHHCCCCCCCEECCCCCCCEEEEEECCEEEECCCCCEEEEECCCCEEEEECCCCCCC
LEIEA
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10651802 [H]