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The map label for this gene is infC

Identifier: 13474222

GI number: 13474222

Start: 4009448

End: 4009984

Strand: Reverse

Name: infC

Synonym: mll5061

Alternate gene names: 13474222

Gene position: 4009984-4009448 (Counterclockwise)

Preceding gene: 13474225

Following gene: 13474221

Centisome position: 56.99

GC content: 59.96

Gene sequence:

>537_bases
ATTCGCAGACCTTTCAAAGCAGCGGCGCCGACCAAGGATGGGCCGCGCTCCAACCGTGACATCCGGGTTCCCCGGGTCCA
GCTTATCGACGCCGAAGGCCAGAACCGCGGCGATGTTTCCATCAACGACGCATTGCTGCTCGCCGAAGAGGCGGGGCTCG
ATCTCGTTGAGATATCGCCCAATGCGGTGCCGCCCGTCGTAAAGATCCTCGATCTCGGCAAGTTGAAATACGCCAACCAG
AAGAAGGCGGCCGAGGCGCGCAAGAATCAGAAGGTCATCGAGATCAAGGAGATCAAGATGCGCCCGAACATCGACAGCCA
TGACTACGAGACCAAGATGAAGGCGGTGCGCCGCTTCTTCGAAGAGGGCGACAAGGTCAAGCTGACATTGCGCTTCCGCG
GCCGCGAGATGGCGCATATGGAACTCGGCATGCAGCTTCTGAACAAGGTGCGCGAGGAAGTGGCGACCATTGCAAAAGTC
GAGGCGGAGCCGAAGCTCGAAGGCCGCCAGATGATGATGGTGCTGGCGCCGCGCTAA

Upstream 100 bases:

>100_bases
CAATGCTGTGCTATTGACTCCGCCCGCGCGCTCACCACATTGGCGCGTCCACGCATCAGACTGACAAATCCTGAACGAAA
CGGCCAAGGAGACCACGACC

Downstream 100 bases:

>100_bases
GGTGTGCTGAATATCAACACCTGAGATCACGATAAAGTCAGGCGTGACCAGCGCTCCAAATCCGCCTGAATTGTCTTGCA
GAGCGTCCCGGCGATCGGCG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MRRPFKAAAPTKDGPRSNRDIRVPRVQLIDAEGQNRGDVSINDALLLAEEAGLDLVEISPNAVPPVVKILDLGKLKYANQ
KKAAEARKNQKVIEIKEIKMRPNIDSHDYETKMKAVRRFFEEGDKVKLTLRFRGREMAHMELGMQLLNKVREEVATIAKV
EAEPKLEGRQMMMVLAPR

Sequences:

>Translated_178_residues
MRRPFKAAAPTKDGPRSNRDIRVPRVQLIDAEGQNRGDVSINDALLLAEEAGLDLVEISPNAVPPVVKILDLGKLKYANQ
KKAAEARKNQKVIEIKEIKMRPNIDSHDYETKMKAVRRFFEEGDKVKLTLRFRGREMAHMELGMQLLNKVREEVATIAKV
EAEPKLEGRQMMMVLAPR
>Mature_178_residues
MRRPFKAAAPTKDGPRSNRDIRVPRVQLIDAEGQNRGDVSINDALLLAEEAGLDLVEISPNAVPPVVKILDLGKLKYANQ
KKAAEARKNQKVIEIKEIKMRPNIDSHDYETKMKAVRRFFEEGDKVKLTLRFRGREMAHMELGMQLLNKVREEVATIAKV
EAEPKLEGRQMMMVLAPR

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=164, Percent_Identity=55.4878048780488, Blast_Score=172, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_RHILO (Q98CP5)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_105790.1
- ProteinModelPortal:   Q98CP5
- SMR:   Q98CP5
- GeneID:   1228450
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll5061
- NMPDR:   fig|266835.1.peg.3894
- HOGENOM:   HBG744268
- OMA:   APKAPIN
- ProtClustDB:   PRK00028
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 20225; Mature: 20225

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRPFKAAAPTKDGPRSNRDIRVPRVQLIDAEGQNRGDVSINDALLLAEEAGLDLVEISP
CCCCCCCCCCCCCCCCCCCCEECCEEEEEECCCCCCCCEEECCEEEEECCCCCEEEEECC
NAVPPVVKILDLGKLKYANQKKAAEARKNQKVIEIKEIKMRPNIDSHDYETKMKAVRRFF
CCCCHHHHHHHCCCCCCCCHHHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHH
EEGDKVKLTLRFRGREMAHMELGMQLLNKVREEVATIAKVEAEPKLEGRQMMMVLAPR
HCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCC
>Mature Secondary Structure
MRRPFKAAAPTKDGPRSNRDIRVPRVQLIDAEGQNRGDVSINDALLLAEEAGLDLVEISP
CCCCCCCCCCCCCCCCCCCCEECCEEEEEECCCCCCCCEEECCEEEEECCCCCEEEEECC
NAVPPVVKILDLGKLKYANQKKAAEARKNQKVIEIKEIKMRPNIDSHDYETKMKAVRRFF
CCCCHHHHHHHCCCCCCCCHHHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHH
EEGDKVKLTLRFRGREMAHMELGMQLLNKVREEVATIAKVEAEPKLEGRQMMMVLAPR
HCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968