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The map label for this gene is ybfF [C]

Identifier: 13473738

GI number: 13473738

Start: 3516632

End: 3517573

Strand: Direct

Name: ybfF [C]

Synonym: mlr4436

Alternate gene names: 13473738

Gene position: 3516632-3517573 (Clockwise)

Preceding gene: 13473732

Following gene: 13473740

Centisome position: 49.98

GC content: 64.01

Gene sequence:

>942_bases
ATGCCGGCCACAGCACACGCGGCGCCATCGATTGGCGCGGATTATGGTGTGCCAGCGGGGTTCTCATCCCGCTTCGCAAC
CGCCAACGGCGTGCGCCTGCACTACGTGATTGGCGGCTCAGGTTCCCCGGTCCTGCTCATCCATGGTTGGCCGGAGACCT
GGTACGAATGGCGCAAGGTGATGCCGCAGCTGGCAGCGGGGCACACGGTGATCGCCGTCGACCTTCGGGGCTTTGGCTGG
TCCGATGTCACAGCCTCGGGCTATGACCGCCGTACGCTGGCCGAGGATCTCTACCAGCTTATGCGGCAATTGGGCTATCC
GAAGGCGACAGTCGTCGGGCACGACTGGGGCGCGCCGGTAGGCTACGCCTATGCGGCCACCCACCGCGACGCCGTTGATC
GGCTCGTCATCGCCGAAGGAGCACCGGACGGTCCGTGGACCCATCAGCAGACGACCCCCTTCGCTCACAATCCCTTCTGG
TTCTTTGGCTTCTTTGAGATCCCCAACTACGCAGAGACCGTGCTCGCGGGACGGGAGACGCCGTTTCTCGACTGGTTCTA
CCGCAACAGGGGCTTCCACGTGGTCCCGGGCGGGTTCTCGGACGACGATGTCGCCTACTTTGAGGAGGCTTACGCCCGCC
CAGGCCGGTTTGCTGCAAGTCTCAATCTTTATCGCACGATTGACCAGGACATCGCGGACAACGCTGTTCTCTCGCAGTCA
CCGCTGACGATCCCGGTGATGGCGATCGGTGCGGATCACGGCATCGGCCAAGGCGTGCCGGCTGGGATGCGTCATGTTGC
CAGCAATGTGACACCTGTGCTGATGGGCGCAACCGGCCACTTCCTGACGGAAGAGCGGCCAACTGCCTTCGTCGAGATCG
TCGAGACGTTCCTCGCCGGTCGGCCGGTCGCGCCCGCCTGGGCACCGGTAGATTCAAAGTGA

Upstream 100 bases:

>100_bases
CGCTCATCGAGTCGCTTCGGCCGGGCACGGCCATCGCCGGGCGTCGGTTGCGACAGGGTTGATCCTCGCGTCGACGCTCG
CTGCGACCCTGATCGGCGCA

Downstream 100 bases:

>100_bases
CATTTGTCCGGGCACACTTCAGGAAATGCGCGTCGCTCAATCCCTCTCCGTCCGAGGGCGAACCGACCGGGATCTGGTTC
GAGGAGATCGCGACGCCGAA

Product: hypothetical protein

Products: NA

Alternate protein names: SEH; Cytosolic epoxide hydrolase; cEH; Epoxide hydratase [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MPATAHAAPSIGADYGVPAGFSSRFATANGVRLHYVIGGSGSPVLLIHGWPETWYEWRKVMPQLAAGHTVIAVDLRGFGW
SDVTASGYDRRTLAEDLYQLMRQLGYPKATVVGHDWGAPVGYAYAATHRDAVDRLVIAEGAPDGPWTHQQTTPFAHNPFW
FFGFFEIPNYAETVLAGRETPFLDWFYRNRGFHVVPGGFSDDDVAYFEEAYARPGRFAASLNLYRTIDQDIADNAVLSQS
PLTIPVMAIGADHGIGQGVPAGMRHVASNVTPVLMGATGHFLTEERPTAFVEIVETFLAGRPVAPAWAPVDSK

Sequences:

>Translated_313_residues
MPATAHAAPSIGADYGVPAGFSSRFATANGVRLHYVIGGSGSPVLLIHGWPETWYEWRKVMPQLAAGHTVIAVDLRGFGW
SDVTASGYDRRTLAEDLYQLMRQLGYPKATVVGHDWGAPVGYAYAATHRDAVDRLVIAEGAPDGPWTHQQTTPFAHNPFW
FFGFFEIPNYAETVLAGRETPFLDWFYRNRGFHVVPGGFSDDDVAYFEEAYARPGRFAASLNLYRTIDQDIADNAVLSQS
PLTIPVMAIGADHGIGQGVPAGMRHVASNVTPVLMGATGHFLTEERPTAFVEIVETFLAGRPVAPAWAPVDSK
>Mature_312_residues
PATAHAAPSIGADYGVPAGFSSRFATANGVRLHYVIGGSGSPVLLIHGWPETWYEWRKVMPQLAAGHTVIAVDLRGFGWS
DVTASGYDRRTLAEDLYQLMRQLGYPKATVVGHDWGAPVGYAYAATHRDAVDRLVIAEGAPDGPWTHQQTTPFAHNPFWF
FGFFEIPNYAETVLAGRETPFLDWFYRNRGFHVVPGGFSDDDVAYFEEAYARPGRFAASLNLYRTIDQDIADNAVLSQSP
LTIPVMAIGADHGIGQGVPAGMRHVASNVTPVLMGATGHFLTEERPTAFVEIVETFLAGRPVAPAWAPVDSK

Specific function: Involved in catabolic degradation of epoxides. Shows highest activity towards C6 and C7 carbocyclic epoxides. Also active towards linear 1,2-epoxyalkanes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI218777840, Length=282, Percent_Identity=26.5957446808511, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI13376164, Length=282, Percent_Identity=26.5957446808511, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI218777837, Length=283, Percent_Identity=23.6749116607774, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI27597073, Length=328, Percent_Identity=25.9146341463415, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17554012, Length=292, Percent_Identity=26.3698630136986, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17562298, Length=215, Percent_Identity=27.906976744186, Blast_Score=107, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639
- InterPro:   IPR010497 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF06441 EHN [H]

EC number: =3.3.2.10 [H]

Molecular weight: Translated: 34077; Mature: 33945

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPATAHAAPSIGADYGVPAGFSSRFATANGVRLHYVIGGSGSPVLLIHGWPETWYEWRKV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCHHHHHHHHH
MPQLAAGHTVIAVDLRGFGWSDVTASGYDRRTLAEDLYQLMRQLGYPKATVVGHDWGAPV
HHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
GYAYAATHRDAVDRLVIAEGAPDGPWTHQQTTPFAHNPFWFFGFFEIPNYAETVLAGRET
CEEEHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHCCCCC
PFLDWFYRNRGFHVVPGGFSDDDVAYFEEAYARPGRFAASLNLYRTIDQDIADNAVLSQS
CCCHHHHHCCCCEEECCCCCCCHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCEECCC
PLTIPVMAIGADHGIGQGVPAGMRHVASNVTPVLMGATGHFLTEERPTAFVEIVETFLAG
CCEEEEEEEECCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCC
RPVAPAWAPVDSK
CCCCCCCCCCCCC
>Mature Secondary Structure 
PATAHAAPSIGADYGVPAGFSSRFATANGVRLHYVIGGSGSPVLLIHGWPETWYEWRKV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEECCCHHHHHHHHH
MPQLAAGHTVIAVDLRGFGWSDVTASGYDRRTLAEDLYQLMRQLGYPKATVVGHDWGAPV
HHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
GYAYAATHRDAVDRLVIAEGAPDGPWTHQQTTPFAHNPFWFFGFFEIPNYAETVLAGRET
CEEEHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHCCCCC
PFLDWFYRNRGFHVVPGGFSDDDVAYFEEAYARPGRFAASLNLYRTIDQDIADNAVLSQS
CCCHHHHHCCCCEEECCCCCCCHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHCCCEECCC
PLTIPVMAIGADHGIGQGVPAGMRHVASNVTPVLMGATGHFLTEERPTAFVEIVETFLAG
CCEEEEEEEECCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCC
RPVAPAWAPVDSK
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9578475 [H]