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The map label for this gene is 13473674

Identifier: 13473674

GI number: 13473674

Start: 3459555

End: 3459851

Strand: Direct

Name: 13473674

Synonym: mlr4350

Alternate gene names: NA

Gene position: 3459555-3459851 (Clockwise)

Preceding gene: 13473672

Following gene: 13473675

Centisome position: 49.17

GC content: 61.28

Gene sequence:

>297_bases
ATGACGAGAGAAAAACTCAGCAAGGACGCCATCACCGCTGCCCTTGCCGAACTCGGCGACTGGTCGCTGGCCACGGACGG
CGCCTCGATCAAGCGCAGCTTCGTCTTCAGGAATTTCTCCGAAGCCTTCGCCTTCATGACCCGCGTCGCGCTGGCCGCCG
AGAAGATGGACCATCATCCCGACTGGTCGAATGTCTACAAGACCGTCGACGTGACGCTGAACACCCATGACGCCGGCGGC
GTCACGGCGCTCGACATCGCGCTGGCCAAGAAGATGAACCACTATTTCGGCGGCTGA

Upstream 100 bases:

>100_bases
TATGCGCCGTTTGTGCATTTGGAACCCCAAAACCGCAAGGCACTTCGGGGCGACTTGCACTATGGTGAGGGTCAAATTCG
AAATAGCACGGGAAATCATC

Downstream 100 bases:

>100_bases
GTGTACGCCTGGCCGTAAGCGGCGAGCCCAAATCGGCACCGGCATCTTGCAGCCGGGTCCGGCTTTCACCACATTTCGCC
TCGCGAGGCATGCGCCAGGA

Product: pterin-4a-carbinolamine dehydratase

Products: NA

Alternate protein names: PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Pterin carbinolamine dehydratase; PCD

Number of amino acids: Translated: 98; Mature: 97

Protein sequence:

>98_residues
MTREKLSKDAITAALAELGDWSLATDGASIKRSFVFRNFSEAFAFMTRVALAAEKMDHHPDWSNVYKTVDVTLNTHDAGG
VTALDIALAKKMNHYFGG

Sequences:

>Translated_98_residues
MTREKLSKDAITAALAELGDWSLATDGASIKRSFVFRNFSEAFAFMTRVALAAEKMDHHPDWSNVYKTVDVTLNTHDAGG
VTALDIALAKKMNHYFGG
>Mature_97_residues
TREKLSKDAITAALAELGDWSLATDGASIKRSFVFRNFSEAFAFMTRVALAAEKMDHHPDWSNVYKTVDVTLNTHDAGGV
TALDIALAKKMNHYFGG

Specific function: Unknown

COG id: COG2154

COG function: function code H; Pterin-4a-carbinolamine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pterin-4-alpha-carbinolamine dehydratase family

Homologues:

Organism=Homo sapiens, GI134133240, Length=70, Percent_Identity=52.8571428571429, Blast_Score=87, Evalue=3e-18,
Organism=Homo sapiens, GI4557831, Length=83, Percent_Identity=45.7831325301205, Blast_Score=82, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI115533705, Length=69, Percent_Identity=56.5217391304348, Blast_Score=93, Evalue=3e-20,
Organism=Drosophila melanogaster, GI45549100, Length=69, Percent_Identity=52.1739130434783, Blast_Score=86, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PHS_RHILO (Q98E92)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_105242.1
- ProteinModelPortal:   Q98E92
- SMR:   Q98E92
- GeneID:   1227903
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr4350
- NMPDR:   fig|266835.1.peg.3346
- HOGENOM:   HBG705804
- OMA:   FNVYSRV
- ProtClustDB:   CLSK506112
- BRENDA:   4.2.1.96
- HAMAP:   MF_00434
- InterPro:   IPR001533
- Gene3D:   G3DSA:3.30.1360.20
- PANTHER:   PTHR12599

Pfam domain/function: PF01329 Pterin_4a; SSF55248 Trans_pterinDh

EC number: =4.2.1.96

Molecular weight: Translated: 10765; Mature: 10634

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTREKLSKDAITAALAELGDWSLATDGASIKRSFVFRNFSEAFAFMTRVALAAEKMDHHP
CCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DWSNVYKTVDVTLNTHDAGGVTALDIALAKKMNHYFGG
CHHHHEEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TREKLSKDAITAALAELGDWSLATDGASIKRSFVFRNFSEAFAFMTRVALAAEKMDHHP
CHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DWSNVYKTVDVTLNTHDAGGVTALDIALAKKMNHYFGG
CHHHHEEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968