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The map label for this gene is yfkJ [H]

Identifier: 13473673

GI number: 13473673

Start: 3458938

End: 3459450

Strand: Reverse

Name: yfkJ [H]

Synonym: mll4349

Alternate gene names: 13473673

Gene position: 3459450-3458938 (Counterclockwise)

Preceding gene: 13473676

Following gene: 13473670

Centisome position: 49.17

GC content: 65.3

Gene sequence:

>513_bases
ATGAGCATAAAGCCGATAAATTCCATTCTGTTTGTCTGCCTCGGCAACATCTGCCGCTCGCCGCTGGCCGAGGGCGTCTT
TCGCACCGTCTGGGCCGAGCGAGGCCAGGGCCGCCATATGCTGCTCGATTCAGCCGCCACCAGCGGCTGGGAGGTCGGCT
CGGCGCCCGATCCACGCTCGATCGCGGTCGCGATGCGTCACGGCATCGACATTTCCGGACAGAGAGCACGCAAGGTCCTG
CGTGAGGATTTCTCCCGTTTCGACCTGATCCTCGGCATGGACCGCTCGAACGTCGCCGACCTCAAGGCGCTGGCGCCCGC
GCGGGACCGGGTGCATCTGTTTTTAGAATTCGCGCACGGACAGGCGCGTGACGTGCCCGATCCCTATTATGACGGGCCGG
AGGCCTTTGCCGAGGTCTACCGCATGATCCGCGAGGCGTCGGAGGCGCTGGCGACGCGGCTGGCGGCGCGGGTATCGTTG
CCGGACAGCGGCCAGGCTTCCTCGACGATATAG

Upstream 100 bases:

>100_bases
ATTTCCCGTGCTATTTCGAATTTGACCCTCACCATAGTGCAAGTCGCCCCGAAGTGCCTTGCGGTTTTGGGGTTCCAAAT
GCACAAACGGCGCATATCGC

Downstream 100 bases:

>100_bases
GGGCCGCCGCCAACCGAATCGCGCGACGACATCAGAACGAAGCGACCGATGCGGAAGGGCAATGTCGAGAAATTGCCGCG
CGCCGACAGATATTGCGCGA

Product: protein-tyrosine-phosphatase

Products: NA

Alternate protein names: LMPTP [H]

Number of amino acids: Translated: 170; Mature: 169

Protein sequence:

>170_residues
MSIKPINSILFVCLGNICRSPLAEGVFRTVWAERGQGRHMLLDSAATSGWEVGSAPDPRSIAVAMRHGIDISGQRARKVL
REDFSRFDLILGMDRSNVADLKALAPARDRVHLFLEFAHGQARDVPDPYYDGPEAFAEVYRMIREASEALATRLAARVSL
PDSGQASSTI

Sequences:

>Translated_170_residues
MSIKPINSILFVCLGNICRSPLAEGVFRTVWAERGQGRHMLLDSAATSGWEVGSAPDPRSIAVAMRHGIDISGQRARKVL
REDFSRFDLILGMDRSNVADLKALAPARDRVHLFLEFAHGQARDVPDPYYDGPEAFAEVYRMIREASEALATRLAARVSL
PDSGQASSTI
>Mature_169_residues
SIKPINSILFVCLGNICRSPLAEGVFRTVWAERGQGRHMLLDSAATSGWEVGSAPDPRSIAVAMRHGIDISGQRARKVLR
EDFSRFDLILGMDRSNVADLKALAPARDRVHLFLEFAHGQARDVPDPYYDGPEAFAEVYRMIREASEALATRLAARVSLP
DSGQASSTI

Specific function: Dephosphorylates the phosphotyrosine-containing proteins. Involved in ethanol stress resistance [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI6005988, Length=157, Percent_Identity=36.3057324840764, Blast_Score=119, Evalue=1e-27,
Organism=Homo sapiens, GI4757714, Length=157, Percent_Identity=38.2165605095541, Blast_Score=116, Evalue=7e-27,
Organism=Homo sapiens, GI96304457, Length=84, Percent_Identity=47.6190476190476, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1788375, Length=152, Percent_Identity=35.5263157894737, Blast_Score=87, Evalue=6e-19,
Organism=Escherichia coli, GI87081812, Length=156, Percent_Identity=36.5384615384615, Blast_Score=86, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6325330, Length=161, Percent_Identity=31.6770186335404, Blast_Score=100, Evalue=1e-22,
Organism=Drosophila melanogaster, GI78706766, Length=140, Percent_Identity=38.5714285714286, Blast_Score=107, Evalue=5e-24,
Organism=Drosophila melanogaster, GI78706768, Length=140, Percent_Identity=38.5714285714286, Blast_Score=107, Evalue=5e-24,
Organism=Drosophila melanogaster, GI78706770, Length=139, Percent_Identity=41.0071942446043, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI78706772, Length=139, Percent_Identity=41.0071942446043, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI78706764, Length=128, Percent_Identity=39.0625, Blast_Score=101, Evalue=3e-22,
Organism=Drosophila melanogaster, GI78711846, Length=148, Percent_Identity=31.7567567567568, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 18667; Mature: 18536

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKPINSILFVCLGNICRSPLAEGVFRTVWAERGQGRHMLLDSAATSGWEVGSAPDPRS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHH
IAVAMRHGIDISGQRARKVLREDFSRFDLILGMDRSNVADLKALAPARDRVHLFLEFAHG
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHEECCC
QARDVPDPYYDGPEAFAEVYRMIREASEALATRLAARVSLPDSGQASSTI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SIKPINSILFVCLGNICRSPLAEGVFRTVWAERGQGRHMLLDSAATSGWEVGSAPDPRS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHH
IAVAMRHGIDISGQRARKVLREDFSRFDLILGMDRSNVADLKALAPARDRVHLFLEFAHG
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHEECCC
QARDVPDPYYDGPEAFAEVYRMIREASEALATRLAARVSLPDSGQASSTI
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]