BacMap

Definition	Mesorhizobium loti MAFF303099 chromosome, complete genome.
Accession	NC_002678
Length	7,036,071

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The map label for this gene is ccmA

Identifier: 13473662

GI number: 13473662

Start: 3446357

End: 3446962

Strand: Reverse

Name: ccmA

Synonym: mll4333

Alternate gene names: 13473662

Gene position: 3446962-3446357 (Counterclockwise)

Preceding gene: 13473664

Following gene: 13473661

Centisome position: 48.99

GC content: 66.34

Gene sequence:

>606_bases
ATGCGGCTTATCGCCGAAAATCTGGGCGGCGAACGCGGCGGCGAGGCGGTTTTTTCCGGCGTCGGCTTTGCGCTCGATCA
GGGCCAGGCGCTGGTCGTCACCGGGCCGAACGGATCGGGCAAATCGACCCTGCTCCGGATCATCGCCGGTCTGCTGCCGA
AGGCCGAAGGCCGGCTGCTGCTCGAGAACGGCGGCGATGACTTTCCGTCGATCGCTTCGGCCTGCCATTATCTCGGACAC
CAGAACGCGATGAAGACGGCGCTAAGTGTCGTGGAAAACCTGCGCTTCTGGCGCGATTTCAATGGCCGTGGCGACTCGGG
CGTCGAAGAGGCGCTGGATACGGTCGGGCTGGGTGGCGTCGGCCATCTGCCGTTCGGCTATCTCTCGACCGGGCAAAGGC
GGCGCGCCGCGATCGCCAAGCTTTTGGTCAGCCATCGGCCGCTGTGGCTGCTCGACGAGCCAACGGCGGGATTGGACAAG
GCGTCGGAGGCGCGGTTTGCCGGGCTGATGGCAGGGCACTGTGCCGGGGGTGGGATGATTGTCGCGGCGACGCATCTGCC
GCTGGGGATCGAGGGGGCGGAGTTGAGGATGGGGGTAGCCGGTTGA

Upstream 100 bases:

>100_bases
CGCATATAGAGAATTTTCTGGAATAGTTCTAGACAGTCGAAAAGCAAATTTGTGCGATGCGGCAGCGACCGCGGAACATT
GTTTTCAGGGCAGGCGAGGG

Downstream 100 bases:

>100_bases
TGGCGGCACTCTACGGCGCCCCCCTCCGTCCTGCCGGACATCTCCCCCACGAGGGGGGAGATTGGCTGTTGGCTCGGGTT
TCGCCAAACTACAGCATCGC

Product: cytochrome c biogenesis protein CcmA

Products: NA

Alternate protein names: Heme exporter protein A

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MRLIAENLGGERGGEAVFSGVGFALDQGQALVVTGPNGSGKSTLLRIIAGLLPKAEGRLLLENGGDDFPSIASACHYLGH
QNAMKTALSVVENLRFWRDFNGRGDSGVEEALDTVGLGGVGHLPFGYLSTGQRRRAAIAKLLVSHRPLWLLDEPTAGLDK
ASEARFAGLMAGHCAGGGMIVAATHLPLGIEGAELRMGVAG

Sequences:

>Translated_201_residues
MRLIAENLGGERGGEAVFSGVGFALDQGQALVVTGPNGSGKSTLLRIIAGLLPKAEGRLLLENGGDDFPSIASACHYLGH
QNAMKTALSVVENLRFWRDFNGRGDSGVEEALDTVGLGGVGHLPFGYLSTGQRRRAAIAKLLVSHRPLWLLDEPTAGLDK
ASEARFAGLMAGHCAGGGMIVAATHLPLGIEGAELRMGVAG
>Mature_201_residues
MRLIAENLGGERGGEAVFSGVGFALDQGQALVVTGPNGSGKSTLLRIIAGLLPKAEGRLLLENGGDDFPSIASACHYLGH
QNAMKTALSVVENLRFWRDFNGRGDSGVEEALDTVGLGGVGHLPFGYLSTGQRRRAAIAKLLVSHRPLWLLDEPTAGLDK
ASEARFAGLMAGHCAGGGMIVAATHLPLGIEGAELRMGVAG

Specific function: Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system

COG id: COG4133

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain

Homologues:

Organism=Homo sapiens, GI46592978, Length=184, Percent_Identity=32.0652173913043, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI46592971, Length=184, Percent_Identity=32.0652173913043, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI46592964, Length=184, Percent_Identity=32.0652173913043, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI46592956, Length=184, Percent_Identity=32.0652173913043, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI46592915, Length=184, Percent_Identity=32.0652173913043, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI46592898, Length=184, Percent_Identity=32.0652173913043, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI215820660, Length=162, Percent_Identity=32.0987654320988, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI20143975, Length=162, Percent_Identity=32.0987654320988, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI153792144, Length=181, Percent_Identity=29.2817679558011, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI105990541, Length=168, Percent_Identity=29.1666666666667, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI9955963, Length=200, Percent_Identity=27.5, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI116734710, Length=168, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=7e-11,
Organism=Escherichia coli, GI87082064, Length=199, Percent_Identity=36.6834170854271, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1790739, Length=196, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1790467, Length=179, Percent_Identity=32.4022346368715, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1786253, Length=167, Percent_Identity=31.7365269461078, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788165, Length=154, Percent_Identity=33.7662337662338, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787029, Length=197, Percent_Identity=29.9492385786802, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1787370, Length=181, Percent_Identity=30.939226519337, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790544, Length=186, Percent_Identity=30.1075268817204, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787792, Length=192, Percent_Identity=29.6875, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787712, Length=159, Percent_Identity=30.8176100628931, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI87081782, Length=189, Percent_Identity=29.1005291005291, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786345, Length=189, Percent_Identity=30.1587301587302, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87081709, Length=158, Percent_Identity=30.379746835443, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1786563, Length=194, Percent_Identity=29.8969072164948, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1786698, Length=188, Percent_Identity=26.063829787234, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1786319, Length=191, Percent_Identity=29.8429319371728, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87081791, Length=166, Percent_Identity=30.1204819277108, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1788053, Length=191, Percent_Identity=28.7958115183246, Blast_Score=60, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=193, Percent_Identity=27.979274611399, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320874, Length=156, Percent_Identity=30.1282051282051, Blast_Score=65, Evalue=7e-12,
Organism=Drosophila melanogaster, GI85724864, Length=187, Percent_Identity=28.3422459893048, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24580555, Length=187, Percent_Identity=28.3422459893048, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI85816269, Length=187, Percent_Identity=28.3422459893048, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24580553, Length=187, Percent_Identity=28.3422459893048, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI28574533, Length=188, Percent_Identity=29.2553191489362, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI161076682, Length=184, Percent_Identity=29.3478260869565, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI161076684, Length=184, Percent_Identity=29.3478260869565, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24581617, Length=184, Percent_Identity=29.3478260869565, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24581615, Length=184, Percent_Identity=29.3478260869565, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI85724858, Length=163, Percent_Identity=30.0613496932515, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI85724856, Length=163, Percent_Identity=30.0613496932515, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24580547, Length=163, Percent_Identity=30.0613496932515, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24580551, Length=163, Percent_Identity=30.0613496932515, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24580549, Length=163, Percent_Identity=30.0613496932515, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24580545, Length=163, Percent_Identity=30.0613496932515, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28574744, Length=185, Percent_Identity=28.1081081081081, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24666836, Length=144, Percent_Identity=34.0277777777778, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI85726357, Length=189, Percent_Identity=30.1587301587302, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24581383, Length=187, Percent_Identity=26.7379679144385, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24581385, Length=187, Percent_Identity=26.7379679144385, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24581387, Length=187, Percent_Identity=26.2032085561497, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI221500365, Length=161, Percent_Identity=29.1925465838509, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI116007184, Length=161, Percent_Identity=29.1925465838509, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CCMA_RHILO (Q98EA4)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_105230.1
- ProteinModelPortal:   Q98EA4
- SMR:   Q98EA4
- GeneID:   1227891
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll4333
- NMPDR:   fig|266835.1.peg.3334
- HOGENOM:   HBG758042
- OMA:   ACDEERT
- ProtClustDB:   PRK13539
- BRENDA:   3.6.3.41
- HAMAP:   MF_01707
- InterPro:   IPR003439
- InterPro:   IPR005895
- InterPro:   IPR003593
- PANTHER:   PTHR19222:SF5
- SMART:   SM00382
- TIGRFAMs:   TIGR01189

Pfam domain/function: PF00005 ABC_tran

EC number: =3.6.3.41

Molecular weight: Translated: 20825; Mature: 20825

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00211 ABC_TRANSPORTER_1; PS50893 ABC_TRANSPORTER_2; PS51243 CCMA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLIAENLGGERGGEAVFSGVGFALDQGQALVVTGPNGSGKSTLLRIIAGLLPKAEGRLL
CCCCCCCCCCCCCCHHHHHHCCEEECCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEE
LENGGDDFPSIASACHYLGHQNAMKTALSVVENLRFWRDFNGRGDSGVEEALDTVGLGGV
EECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCC
GHLPFGYLSTGQRRRAAIAKLLVSHRPLWLLDEPTAGLDKASEARFAGLMAGHCAGGGMI
CCCCCCHHCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEE
VAATHLPLGIEGAELRMGVAG
EEEECCCCCCCCHHEEECCCC
>Mature Secondary Structure
MRLIAENLGGERGGEAVFSGVGFALDQGQALVVTGPNGSGKSTLLRIIAGLLPKAEGRLL
CCCCCCCCCCCCCCHHHHHHCCEEECCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEE
LENGGDDFPSIASACHYLGHQNAMKTALSVVENLRFWRDFNGRGDSGVEEALDTVGLGGV
EECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCC
GHLPFGYLSTGQRRRAAIAKLLVSHRPLWLLDEPTAGLDKASEARFAGLMAGHCAGGGMI
CCCCCCHHCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEE
VAATHLPLGIEGAELRMGVAG
EEEECCCCCCCCHHEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11214968