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The map label for this gene is cycW [H]

Identifier: 13473661

GI number: 13473661

Start: 3445480

End: 3446145

Strand: Reverse

Name: cycW [H]

Synonym: mll4332

Alternate gene names: 13473661

Gene position: 3446145-3445480 (Counterclockwise)

Preceding gene: 13473662

Following gene: 13473660

Centisome position: 48.98

GC content: 68.47

Gene sequence:

>666_bases
ATGTGGTCCCTCTTTGCCCGCGACATCCGCCTCAACATCCGTGCCGGCGGCGGCGCGTTGACCGGCGTCATCTTCTTCCT
CGCCGTCATCGCCACCATTCCGTTCGGCGTCGGGCCGGACCTGAAGCTGCTTTCCCGCATCGGCCCGGCGATCCTGTGGA
TCGGCGCGCTGCTTGCCTGCCTGCTTGGGCTCGACCGGCTGTTCCAGGCGGACCGCGAGGACGGCTCGCTCGATCTGCTG
GTGCTGGGCAACGACCGGCACATGCTGGCGCTGACGGTGCTGGTGAAATGCCTGGCGCATTGGGCGGGCAGCGTTCTGCC
GCTGGTCGTCGCTGCTCCCCTGCTCGGCCTGTTCATGAACATGGAGCCGCTCGCGATCGGCGCGACGGCGCTGACCCTGC
TGGTCGGCACGCCGGCCATCACCTTCATCGGCGCTGCGGGTGCCGCGGTGGCGGTGGCGCTGCCGCGCGGCGGGCTTCTG
ATCTCGGTGCTGGTGCTGCCGCTGACCATACCGGTGCTGATCTTCGGCGTTTCGGCGAGCTACGGCGCGACGGCCAATCC
CGATCCTTTCCTGCAGCCCTTCCTCATTCTTGCCGCGCTGACGCTGTTTCTTGCCGTGCTGGGGCCGGTCTCGGCGGCGC
TTGCGCTGCGGCATGGAACGGATTGA

Upstream 100 bases:

>100_bases
CGACGGCGAAGCTTGCGATCTCCCCCCTTGTGGGGGAGATGGCCGGCAGGCCAGAGAGGGGCGTCACAGAACACCGTCCT
CAACAAGGGACCACATCGTA

Downstream 100 bases:

>100_bases
GCGAGGTTTGGCATGGTTTGCGCGACATCAAGGCGGCGGCGCGGCGGCCACGTATGTTTGAAACCGCGGCGCGTTGCGCA
GCCATGGGCATGTCGCTAAG

Product: cytochrome c biogenesis protein CycW

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycW [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MWSLFARDIRLNIRAGGGALTGVIFFLAVIATIPFGVGPDLKLLSRIGPAILWIGALLACLLGLDRLFQADREDGSLDLL
VLGNDRHMLALTVLVKCLAHWAGSVLPLVVAAPLLGLFMNMEPLAIGATALTLLVGTPAITFIGAAGAAVAVALPRGGLL
ISVLVLPLTIPVLIFGVSASYGATANPDPFLQPFLILAALTLFLAVLGPVSAALALRHGTD

Sequences:

>Translated_221_residues
MWSLFARDIRLNIRAGGGALTGVIFFLAVIATIPFGVGPDLKLLSRIGPAILWIGALLACLLGLDRLFQADREDGSLDLL
VLGNDRHMLALTVLVKCLAHWAGSVLPLVVAAPLLGLFMNMEPLAIGATALTLLVGTPAITFIGAAGAAVAVALPRGGLL
ISVLVLPLTIPVLIFGVSASYGATANPDPFLQPFLILAALTLFLAVLGPVSAALALRHGTD
>Mature_221_residues
MWSLFARDIRLNIRAGGGALTGVIFFLAVIATIPFGVGPDLKLLSRIGPAILWIGALLACLLGLDRLFQADREDGSLDLL
VLGNDRHMLALTVLVKCLAHWAGSVLPLVVAAPLLGLFMNMEPLAIGATALTLLVGTPAITFIGAAGAAVAVALPRGGLL
ISVLVLPLTIPVLIFGVSASYGATANPDPFLQPFLILAALTLFLAVLGPVSAALALRHGTD

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=218, Percent_Identity=43.1192660550459, Blast_Score=116, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 22797; Mature: 22797

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWSLFARDIRLNIRAGGGALTGVIFFLAVIATIPFGVGPDLKLLSRIGPAILWIGALLAC
CCCHHEEHEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LLGLDRLFQADREDGSLDLLVLGNDRHMLALTVLVKCLAHWAGSVLPLVVAAPLLGLFMN
HHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHC
MEPLAIGATALTLLVGTPAITFIGAAGAAVAVALPRGGLLISVLVLPLTIPVLIFGVSAS
CCCHHHHHHHHHHHHCCHHHHHHHCCHHHEEEECCCCCHHHHHHHHHHHHHHHHHHCCCC
YGATANPDPFLQPFLILAALTLFLAVLGPVSAALALRHGTD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MWSLFARDIRLNIRAGGGALTGVIFFLAVIATIPFGVGPDLKLLSRIGPAILWIGALLAC
CCCHHEEHEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LLGLDRLFQADREDGSLDLLVLGNDRHMLALTVLVKCLAHWAGSVLPLVVAAPLLGLFMN
HHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHC
MEPLAIGATALTLLVGTPAITFIGAAGAAVAVALPRGGLLISVLVLPLTIPVLIFGVSAS
CCCHHHHHHHHHHHHCCHHHHHHHCCHHHEEEECCCCCHHHHHHHHHHHHHHHHHHCCCC
YGATANPDPFLQPFLILAALTLFLAVLGPVSAALALRHGTD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]