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The map label for this gene is ftsK

Identifier: 13473592

GI number: 13473592

Start: 3384006

End: 3386669

Strand: Reverse

Name: ftsK

Synonym: mll4243

Alternate gene names: 13473592

Gene position: 3386669-3384006 (Counterclockwise)

Preceding gene: 13473593

Following gene: 13473591

Centisome position: 48.13

GC content: 65.99

Gene sequence:

>2664_bases
ATGCGTTCAGGGGCTTCAGCACCGCTCGCGATGACCGATACGGGGCACGGCATCCAGGCTTTCGCGCGGCGCCAGGTCGG
CCGGCTGGTCGGCGCCGGCATGTTTCTGGCTGTAGCCTTCGGGGTTGCCAGCCTCGCCACCTGGAACGTTGCCGATCCAA
GCTTCTCGCACGCCACCAACAACACCGTCACCAACGCCATGGGCTATGCCGGCGCGGTTTTCTCCGATCTCGCCATGCAG
TTCTTCGGCCTTGCTGCGGTCGCCGCGCTGGTTCCGGCTGTCATCTGGGGGTACCTGCTGTTTTCGGCGCGCGGTGTCGA
CAGGCTGCCCAAGCGCGGGCTGTTCTGGTTCGGCTTCGCCCTGCTCGCCGCCGCGATCGCCGGCTGCATCGTTCCGCCCA
AGACCTGGCCGCTGCCCACCGGCCTCGGCGGCGTGTTCGGCGACATGGTGCTCAAGATTCCCGGCGTCCTGATCGGCGGC
TATCCGACCGGGCTGATCGCCAGCGTGCTCGCCGTGCTGCTGGCCGGGCCGACGCTCTGGCTGTTCGCCTTTGGCTCGGC
GTTGATCGGGCGCAAGAACGGCTTCGCCGTGATGGAAGAGCCGGCGGCAGCGGACCCGCGCGAGGACGATCTTCTGTTCG
ACAATGAAGAGGATGAGGGCGACGAGGGCATATTAGCGCTCGGCGCCATCACTCATTGGTGGCTGTCGCTGCGCGCGTGG
ATGCATCGCCGCGCGGTGCGCCGCAGGCAGGAACGCGACGAATACGAGCCGGAGATGGAGCCGCGCGCCAGCGCCTGGCG
GCGCGCTGCCGAGCGCGTGGAATCGGCCGAATTCGCCGAGCAACGGATGAGCCCGGGTGGCCGCGCCCGCGTCGAGCCGG
AATTCTTCGCCGCCATGGTCAATGACCGCAGCGTTTCCGTGGATCCGGACGATGACGATATCTTCGACCGTGACGACGAG
GACATGGATTTCGACGACGAGCCCGTCGCCCAGCGCCGTGCGGCCCCCGCCGCCAAGGTACAGCAGTTCCGTTCGGATGC
CGCCACCCGCGTCGAGGCGCCGGCGCCGCGCCCGGCGCCTGGCGCGCGCGTCCAGCGCGAGGCGCAGACCTCGCTGATCG
GCTCGGACAAATTCGAAATGCCGTCGCTGCATTTCCTGTCCGAACCGAAGAATGTCGCGCGCGACCCAAGTCTCTCCAAG
GACGCGCTGGAACAGAATGCGCGCCTGCTTGAAGGCGTGCTGGAGGATTTCGGCGTCAAGGGCGAGATCATCGCCGTGCG
CCCGGGTCCCGTCGTCACCCTCTATGAGCTGGAACCCGCGCCCGGCATCAAATCGTCGCGCGTCATCGGCCTCTCCGACG
ACATCGCCCGCTCGATGAGCGCGATCGCCTGCCGCGTCGCCGTGGTGCCCGGCCGCAACGCCATCGGTATCGAGCTGCCG
AACGCCAAGCGCGAGACGGTGTATCTGCGCGAGATCATGGCCAGCCGCGATTTCGAGACGACCAAGGCAAAACTGGCGCT
GGCGCTGGGCAAGACCATCAATGGCGAGGCCGTCATCGTCGACATCGCCAAGATGCCGCACGTGCTGGTCGCCGGCACCA
CTGGCTCCGGCAAGTCGGTCGCCATCAACACCATGATCCTGTCGCTGCTCTACCGGCTGACGCCGCAGGAATGCCGGCTG
ATCATGATCGATCCGAAGATGCTGGAACTCTCCGTCTATGACGGCATCCCGCACCTGCTCACGCCTGTTGTCACCGATCC
GAAGAAGGCGGTGGTGGCGCTGAAATGGACTGTGCGCGAGATGGAGGACCGCTACCGCAAGATGTCCAAGGTCGGCGTGC
GCAACATCGACGGTTTCAACGCCCGCGTTCAGCTGGCCGAGAAAAAGGGCGAAAAAATCTCGCGCACCGTGCAGACCGGT
TTCGACCGCCAGACCGGCGAGGCGATCTACGAGACGGAGGACCTCGATCTCGAGCCGATGCCCTATATCGTCGTCATCAT
CGACGAAATGGCCGACCTGATGATGGTCGCCGGCAAGGACATCGAAGGCGCGGTGCAGCGCCTGGCGCAGATGGCGCGCG
CCGCCGGCATCCATGTCATCATGGCGACGCAGCGTCCGTCGGTCGACGTCATCACCGGCACCATCAAGGCCAATTTCCCG
ACCCGCATCTCCTTCCAGGTGACGTCGAAGATCGACAGCCGCACCATTCTGGGCGAGCAGGGCGCTGAGCAGCTGCTCGG
CATGGGCGACATGCTCTACATGGCCGGCGGCGGCCGCATCCAGCGCGTGCACGGCCCCTTCGTCTCCGACGACGAGGTCG
AAAAGATCGTCGGGCACCTGAAACTGCAGGGCGTGCCCGAATATCTCGACGCCATCACCGAGGACGACGACGAGGACGAC
GACGAACCGTCCGGCAAGGGCGCTGGCTCCGGTGGCGGTGGCGGCGGCAATTTCGAGGATTCCGACGATCCCTACGACCA
GGCGGTGGCGGTGGTGCTGCGCGACGGCAAGGCGTCGACCAGTTACATCCAGCGCCGGCTCGGCATCGGCTACAACCGCG
CCGCCTCGATCATCGAGAAGATGGAGAAGGAAGGCATTGTCGGCCCGGCAAACCATGCGGGAAAACGCGAAATCCTGGTG
CCGACCGAGGACGACAAGTTCTGA

Upstream 100 bases:

>100_bases
ATAGTTAATGCCCCCTTAACCTTCCCACCGATAGTCTGGCGTTCGAATCTGCCGGAGTGCGTCATGTGCTCGGGCCAGGC
AATCACTGACGGGGAAGAGC

Downstream 100 bases:

>100_bases
TGGCGGGGCGTTCACGGCAACTTTGAACCCTCTGGCGCGTTCAAGCAATTAAGCAGCGTTCGCCCCGCCAAACTTCAGCC
CAACTGGGGGTTCAGGACAG

Product: cell division protein ftsK-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 887; Mature: 887

Protein sequence:

>887_residues
MRSGASAPLAMTDTGHGIQAFARRQVGRLVGAGMFLAVAFGVASLATWNVADPSFSHATNNTVTNAMGYAGAVFSDLAMQ
FFGLAAVAALVPAVIWGYLLFSARGVDRLPKRGLFWFGFALLAAAIAGCIVPPKTWPLPTGLGGVFGDMVLKIPGVLIGG
YPTGLIASVLAVLLAGPTLWLFAFGSALIGRKNGFAVMEEPAAADPREDDLLFDNEEDEGDEGILALGAITHWWLSLRAW
MHRRAVRRRQERDEYEPEMEPRASAWRRAAERVESAEFAEQRMSPGGRARVEPEFFAAMVNDRSVSVDPDDDDIFDRDDE
DMDFDDEPVAQRRAAPAAKVQQFRSDAATRVEAPAPRPAPGARVQREAQTSLIGSDKFEMPSLHFLSEPKNVARDPSLSK
DALEQNARLLEGVLEDFGVKGEIIAVRPGPVVTLYELEPAPGIKSSRVIGLSDDIARSMSAIACRVAVVPGRNAIGIELP
NAKRETVYLREIMASRDFETTKAKLALALGKTINGEAVIVDIAKMPHVLVAGTTGSGKSVAINTMILSLLYRLTPQECRL
IMIDPKMLELSVYDGIPHLLTPVVTDPKKAVVALKWTVREMEDRYRKMSKVGVRNIDGFNARVQLAEKKGEKISRTVQTG
FDRQTGEAIYETEDLDLEPMPYIVVIIDEMADLMMVAGKDIEGAVQRLAQMARAAGIHVIMATQRPSVDVITGTIKANFP
TRISFQVTSKIDSRTILGEQGAEQLLGMGDMLYMAGGGRIQRVHGPFVSDDEVEKIVGHLKLQGVPEYLDAITEDDDEDD
DEPSGKGAGSGGGGGGNFEDSDDPYDQAVAVVLRDGKASTSYIQRRLGIGYNRAASIIEKMEKEGIVGPANHAGKREILV
PTEDDKF

Sequences:

>Translated_887_residues
MRSGASAPLAMTDTGHGIQAFARRQVGRLVGAGMFLAVAFGVASLATWNVADPSFSHATNNTVTNAMGYAGAVFSDLAMQ
FFGLAAVAALVPAVIWGYLLFSARGVDRLPKRGLFWFGFALLAAAIAGCIVPPKTWPLPTGLGGVFGDMVLKIPGVLIGG
YPTGLIASVLAVLLAGPTLWLFAFGSALIGRKNGFAVMEEPAAADPREDDLLFDNEEDEGDEGILALGAITHWWLSLRAW
MHRRAVRRRQERDEYEPEMEPRASAWRRAAERVESAEFAEQRMSPGGRARVEPEFFAAMVNDRSVSVDPDDDDIFDRDDE
DMDFDDEPVAQRRAAPAAKVQQFRSDAATRVEAPAPRPAPGARVQREAQTSLIGSDKFEMPSLHFLSEPKNVARDPSLSK
DALEQNARLLEGVLEDFGVKGEIIAVRPGPVVTLYELEPAPGIKSSRVIGLSDDIARSMSAIACRVAVVPGRNAIGIELP
NAKRETVYLREIMASRDFETTKAKLALALGKTINGEAVIVDIAKMPHVLVAGTTGSGKSVAINTMILSLLYRLTPQECRL
IMIDPKMLELSVYDGIPHLLTPVVTDPKKAVVALKWTVREMEDRYRKMSKVGVRNIDGFNARVQLAEKKGEKISRTVQTG
FDRQTGEAIYETEDLDLEPMPYIVVIIDEMADLMMVAGKDIEGAVQRLAQMARAAGIHVIMATQRPSVDVITGTIKANFP
TRISFQVTSKIDSRTILGEQGAEQLLGMGDMLYMAGGGRIQRVHGPFVSDDEVEKIVGHLKLQGVPEYLDAITEDDDEDD
DEPSGKGAGSGGGGGGNFEDSDDPYDQAVAVVLRDGKASTSYIQRRLGIGYNRAASIIEKMEKEGIVGPANHAGKREILV
PTEDDKF
>Mature_887_residues
MRSGASAPLAMTDTGHGIQAFARRQVGRLVGAGMFLAVAFGVASLATWNVADPSFSHATNNTVTNAMGYAGAVFSDLAMQ
FFGLAAVAALVPAVIWGYLLFSARGVDRLPKRGLFWFGFALLAAAIAGCIVPPKTWPLPTGLGGVFGDMVLKIPGVLIGG
YPTGLIASVLAVLLAGPTLWLFAFGSALIGRKNGFAVMEEPAAADPREDDLLFDNEEDEGDEGILALGAITHWWLSLRAW
MHRRAVRRRQERDEYEPEMEPRASAWRRAAERVESAEFAEQRMSPGGRARVEPEFFAAMVNDRSVSVDPDDDDIFDRDDE
DMDFDDEPVAQRRAAPAAKVQQFRSDAATRVEAPAPRPAPGARVQREAQTSLIGSDKFEMPSLHFLSEPKNVARDPSLSK
DALEQNARLLEGVLEDFGVKGEIIAVRPGPVVTLYELEPAPGIKSSRVIGLSDDIARSMSAIACRVAVVPGRNAIGIELP
NAKRETVYLREIMASRDFETTKAKLALALGKTINGEAVIVDIAKMPHVLVAGTTGSGKSVAINTMILSLLYRLTPQECRL
IMIDPKMLELSVYDGIPHLLTPVVTDPKKAVVALKWTVREMEDRYRKMSKVGVRNIDGFNARVQLAEKKGEKISRTVQTG
FDRQTGEAIYETEDLDLEPMPYIVVIIDEMADLMMVAGKDIEGAVQRLAQMARAAGIHVIMATQRPSVDVITGTIKANFP
TRISFQVTSKIDSRTILGEQGAEQLLGMGDMLYMAGGGRIQRVHGPFVSDDEVEKIVGHLKLQGVPEYLDAITEDDDEDD
DEPSGKGAGSGGGGGGNFEDSDDPYDQAVAVVLRDGKASTSYIQRRLGIGYNRAASIIEKMEKEGIVGPANHAGKREILV
PTEDDKF

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain

Homologues:

Organism=Escherichia coli, GI1787117, Length=509, Percent_Identity=51.6699410609037, Blast_Score=494, Evalue=1e-140,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSK_RHILO (Q98EH3)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_105160.1
- ProteinModelPortal:   Q98EH3
- SMR:   Q98EH3
- GeneID:   1227821
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll4243
- NMPDR:   fig|266835.1.peg.3264
- HOGENOM:   HBG662140
- OMA:   IGVRNID
- ProtClustDB:   CLSK506086
- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- SMART:   SM00382
- SMART:   SM00843

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE

EC number: NA

Molecular weight: Translated: 96131; Mature: 96131

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x13262384)-; HASH(0x11ba6d48)-; HASH(0x104be390)-; HASH(0x1207dcec)-; HASH(0x1301c7bc)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSGASAPLAMTDTGHGIQAFARRQVGRLVGAGMFLAVAFGVASLATWNVADPSFSHATN
CCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
NTVTNAMGYAGAVFSDLAMQFFGLAAVAALVPAVIWGYLLFSARGVDRLPKRGLFWFGFA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHH
LLAAAIAGCIVPPKTWPLPTGLGGVFGDMVLKIPGVLIGGYPTGLIASVLAVLLAGPTLW
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHCHHHH
LFAFGSALIGRKNGFAVMEEPAAADPREDDLLFDNEEDEGDEGILALGAITHWWLSLRAW
HHHHHHHHHCCCCCCEEEECCCCCCCCCCCCEECCCCCCCCCCEEEHHHHHHHHHHHHHH
MHRRAVRRRQERDEYEPEMEPRASAWRRAAERVESAEFAEQRMSPGGRARVEPEFFAAMV
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
NDRSVSVDPDDDDIFDRDDEDMDFDDEPVAQRRAAPAAKVQQFRSDAATRVEAPAPRPAP
CCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCC
GARVQREAQTSLIGSDKFEMPSLHFLSEPKNVARDPSLSKDALEQNARLLEGVLEDFGVK
CCHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCC
GEIIAVRPGPVVTLYELEPAPGIKSSRVIGLSDDIARSMSAIACRVAVVPGRNAIGIELP
CEEEEECCCCEEEEEEECCCCCCCCCEEECCCHHHHHHHHHHEEEEEEECCCCEEEEECC
NAKRETVYLREIMASRDFETTKAKLALALGKTINGEAVIVDIAKMPHVLVAGTTGSGKSV
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCCEE
AINTMILSLLYRLTPQECRLIMIDPKMLELSVYDGIPHLLTPVVTDPKKAVVALKWTVRE
HHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCCHHHHCCCCCCCCCEEEEEHHHHHH
MEDRYRKMSKVGVRNIDGFNARVQLAEKKGEKISRTVQTGFDRQTGEAIYETEDLDLEPM
HHHHHHHHHHCCCCCCCCCCCEEEEHHHCCHHHHHHHHHCCCCCCCCCEEECCCCCCCCC
PYIVVIIDEMADLMMVAGKDIEGAVQRLAQMARAAGIHVIMATQRPSVDVITGTIKANFP
CEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEEEEEECCC
TRISFQVTSKIDSRTILGEQGAEQLLGMGDMLYMAGGGRIQRVHGPFVSDDEVEKIVGHL
CEEEEEEECCCCCHHHHCHHHHHHHHCCCCEEEEECCCEEEEECCCCCCCHHHHHHHHHH
KLQGVPEYLDAITEDDDEDDDEPSGKGAGSGGGGGGNFEDSDDPYDQAVAVVLRDGKAST
HCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEEEEEECCCCHH
SYIQRRLGIGYNRAASIIEKMEKEGIVGPANHAGKREILVPTEDDKF
HHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCH
>Mature Secondary Structure
MRSGASAPLAMTDTGHGIQAFARRQVGRLVGAGMFLAVAFGVASLATWNVADPSFSHATN
CCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
NTVTNAMGYAGAVFSDLAMQFFGLAAVAALVPAVIWGYLLFSARGVDRLPKRGLFWFGFA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCHHHHHHH
LLAAAIAGCIVPPKTWPLPTGLGGVFGDMVLKIPGVLIGGYPTGLIASVLAVLLAGPTLW
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHCHHHH
LFAFGSALIGRKNGFAVMEEPAAADPREDDLLFDNEEDEGDEGILALGAITHWWLSLRAW
HHHHHHHHHCCCCCCEEEECCCCCCCCCCCCEECCCCCCCCCCEEEHHHHHHHHHHHHHH
MHRRAVRRRQERDEYEPEMEPRASAWRRAAERVESAEFAEQRMSPGGRARVEPEFFAAMV
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
NDRSVSVDPDDDDIFDRDDEDMDFDDEPVAQRRAAPAAKVQQFRSDAATRVEAPAPRPAP
CCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCC
GARVQREAQTSLIGSDKFEMPSLHFLSEPKNVARDPSLSKDALEQNARLLEGVLEDFGVK
CCHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCC
GEIIAVRPGPVVTLYELEPAPGIKSSRVIGLSDDIARSMSAIACRVAVVPGRNAIGIELP
CEEEEECCCCEEEEEEECCCCCCCCCEEECCCHHHHHHHHHHEEEEEEECCCCEEEEECC
NAKRETVYLREIMASRDFETTKAKLALALGKTINGEAVIVDIAKMPHVLVAGTTGSGKSV
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCCEE
AINTMILSLLYRLTPQECRLIMIDPKMLELSVYDGIPHLLTPVVTDPKKAVVALKWTVRE
HHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCCHHHHCCCCCCCCCEEEEEHHHHHH
MEDRYRKMSKVGVRNIDGFNARVQLAEKKGEKISRTVQTGFDRQTGEAIYETEDLDLEPM
HHHHHHHHHHCCCCCCCCCCCEEEEHHHCCHHHHHHHHHCCCCCCCCCEEECCCCCCCCC
PYIVVIIDEMADLMMVAGKDIEGAVQRLAQMARAAGIHVIMATQRPSVDVITGTIKANFP
CEEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEEEEEECCC
TRISFQVTSKIDSRTILGEQGAEQLLGMGDMLYMAGGGRIQRVHGPFVSDDEVEKIVGHL
CEEEEEEECCCCCHHHHCHHHHHHHHCCCCEEEEECCCEEEEECCCCCCCHHHHHHHHHH
KLQGVPEYLDAITEDDDEDDDEPSGKGAGSGGGGGGNFEDSDDPYDQAVAVVLRDGKAST
HCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEEEEEECCCCHH
SYIQRRLGIGYNRAASIIEKMEKEGIVGPANHAGKREILVPTEDDKF
HHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11214968