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The map label for this gene is aspC [H]

Identifier: 13473569

GI number: 13473569

Start: 3365180

End: 3366262

Strand: Direct

Name: aspC [H]

Synonym: mlr4213

Alternate gene names: 13473569

Gene position: 3365180-3366262 (Clockwise)

Preceding gene: 13473568

Following gene: 13473570

Centisome position: 47.83

GC content: 64.54

Gene sequence:

>1083_bases
GTGATCGAGAAAGAGGCGCCGGAAGAGTACGGTTACGACCGCATCCGCTACAATCTCTCCGAAAGTTCGATCGCCGACCA
GAAGCTCTCCGACATCGGCCTGTCGCTGCCTGACCTCACGCTGTTCTATGGCGAGCATCGCGGCGACAAGGAATTGCGCG
TGCTGATTGCGGCGCAGGACGCCGGCGTCTCGCCTGACGACGTCCTGGTCACCGCCGGTGCCGCCGGCGCGCTGTTCATC
ATCTCGACATCGCTGTTGTCGGCGAGCGACCATCTCGTCGTCATCAGGCCGAACTACGCCACCAACATCGAAACCCCGCG
CGCGATCGGCTGCGCCATCAGCTTCGTCGACCTCGCCTTCGAGGACGGCTTTGCCATCGACGTCCAGGCCATCAAGGCGG
CGATGCGGCCGAACACGAAACTGATCAGCGTTACTTGCCCGCACAACCCGACCGGCACGATGATGTCGCGCCCCGATCTC
GACGCGCTGGTGGTGCTCGCGGAAAGCCGCAACTGCCTTCTGCTGGTCGACGAGACCTATCGCGACCTTTCCTATGGCAA
ACGCCTGCCGTCGGCGGCCTCGCTGAGCCCACGGGCGATCAGCGTCTCGTCGCTGTCCAAGGCCTTCGGCATTCCCGGCA
TCCGCATCGGCTGGCTGATCACCAGGGATGCGGACCTTCAGGAGACGTTCCTTGCCGCCAAGGAGCAGATCGGCATCTGC
GGCAGCGTCATCGACGAAGGCATTGCGCGCGGCATGCTGCAGCGCCGGGACGCCTTCCTGGCGGCGCTGCTGCCCGAAAT
GGCCAAACGCCGCGACATCGTCCAGGCCTGGATCGACCGCGAGCCGCTGGTCGACTGGGTGCGGCCCGAAGGCGGTGTCG
TCGGCTTCCCGCGCCTCAATGTCGAACCCGGCTTCGACCTCGACCGCTTCTATGTGAACCTGCTGGAGAACCATGGCACC
TATGTCGGGCCCGGCCACTGGTTCGAGATGGAAAAACGCTTCTTCCGCGTCGGCTTCGGCTGGCCGACGGAAGCGGAGTT
GCAAGGTGGGCTCGACGCCATTTCGGCAGCACTTCGGCAGTAA

Upstream 100 bases:

>100_bases
ATTTGTCGTTTGACGGTCAAAGCGTTGACAACAGGCCTTCGCTGCTGAGATGGAGCTTAGGCTAACGTCTCCGGGGGAAG
CCATGAACTACACCAGGATG

Downstream 100 bases:

>100_bases
CTTCCTTGTGCGATGGACTCAACAGGCTGAAATCCCTTGATCCAGTGCTGATTTTGGCACACATCCCGCATCGAACTTTG
CTAGACGTTCCATCGGTCGG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MIEKEAPEEYGYDRIRYNLSESSIADQKLSDIGLSLPDLTLFYGEHRGDKELRVLIAAQDAGVSPDDVLVTAGAAGALFI
ISTSLLSASDHLVVIRPNYATNIETPRAIGCAISFVDLAFEDGFAIDVQAIKAAMRPNTKLISVTCPHNPTGTMMSRPDL
DALVVLAESRNCLLLVDETYRDLSYGKRLPSAASLSPRAISVSSLSKAFGIPGIRIGWLITRDADLQETFLAAKEQIGIC
GSVIDEGIARGMLQRRDAFLAALLPEMAKRRDIVQAWIDREPLVDWVRPEGGVVGFPRLNVEPGFDLDRFYVNLLENHGT
YVGPGHWFEMEKRFFRVGFGWPTEAELQGGLDAISAALRQ

Sequences:

>Translated_360_residues
MIEKEAPEEYGYDRIRYNLSESSIADQKLSDIGLSLPDLTLFYGEHRGDKELRVLIAAQDAGVSPDDVLVTAGAAGALFI
ISTSLLSASDHLVVIRPNYATNIETPRAIGCAISFVDLAFEDGFAIDVQAIKAAMRPNTKLISVTCPHNPTGTMMSRPDL
DALVVLAESRNCLLLVDETYRDLSYGKRLPSAASLSPRAISVSSLSKAFGIPGIRIGWLITRDADLQETFLAAKEQIGIC
GSVIDEGIARGMLQRRDAFLAALLPEMAKRRDIVQAWIDREPLVDWVRPEGGVVGFPRLNVEPGFDLDRFYVNLLENHGT
YVGPGHWFEMEKRFFRVGFGWPTEAELQGGLDAISAALRQ
>Mature_360_residues
MIEKEAPEEYGYDRIRYNLSESSIADQKLSDIGLSLPDLTLFYGEHRGDKELRVLIAAQDAGVSPDDVLVTAGAAGALFI
ISTSLLSASDHLVVIRPNYATNIETPRAIGCAISFVDLAFEDGFAIDVQAIKAAMRPNTKLISVTCPHNPTGTMMSRPDL
DALVVLAESRNCLLLVDETYRDLSYGKRLPSAASLSPRAISVSSLSKAFGIPGIRIGWLITRDADLQETFLAAKEQIGIC
GSVIDEGIARGMLQRRDAFLAALLPEMAKRRDIVQAWIDREPLVDWVRPEGGVVGFPRLNVEPGFDLDRFYVNLLENHGT
YVGPGHWFEMEKRFFRVGFGWPTEAELQGGLDAISAALRQ

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=278, Percent_Identity=24.4604316546763, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI56713254, Length=228, Percent_Identity=25.8771929824561, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI4507369, Length=308, Percent_Identity=23.3766233766234, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI95147551, Length=223, Percent_Identity=22.8699551569507, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI169881279, Length=223, Percent_Identity=22.8699551569507, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1788627, Length=250, Percent_Identity=23.6, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1786816, Length=188, Percent_Identity=26.5957446808511, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787710, Length=311, Percent_Identity=25.4019292604502, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17567369, Length=246, Percent_Identity=27.2357723577236, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17567663, Length=293, Percent_Identity=24.9146757679181, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71994476, Length=206, Percent_Identity=25.7281553398058, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71994472, Length=206, Percent_Identity=25.7281553398058, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6322401, Length=189, Percent_Identity=27.5132275132275, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28573069, Length=244, Percent_Identity=22.9508196721311, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24646114, Length=244, Percent_Identity=22.9508196721311, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI28573067, Length=244, Percent_Identity=22.9508196721311, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI28573065, Length=244, Percent_Identity=22.9508196721311, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI18859735, Length=304, Percent_Identity=21.3815789473684, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 39511; Mature: 39511

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEKEAPEEYGYDRIRYNLSESSIADQKLSDIGLSLPDLTLFYGEHRGDKELRVLIAAQD
CCCCCCCHHCCCCCEEEECCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEEEECC
AGVSPDDVLVTAGAAGALFIISTSLLSASDHLVVIRPNYATNIETPRAIGCAISFVDLAF
CCCCCCCEEEECCCCCEEEEEEHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHEEHHHC
EDGFAIDVQAIKAAMRPNTKLISVTCPHNPTGTMMSRPDLDALVVLAESRNCLLLVDETY
CCCCEEEHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCHH
RDLSYGKRLPSAASLSPRAISVSSLSKAFGIPGIRIGWLITRDADLQETFLAAKEQIGIC
HHHHHHHCCCCCCCCCCCEEEHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHCCCH
GSVIDEGIARGMLQRRDAFLAALLPEMAKRRDIVQAWIDREPLVDWVRPEGGVVGFPRLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCEEECCCCC
VEPGFDLDRFYVNLLENHGTYVGPGHWFEMEKRFFRVGFGWPTEAELQGGLDAISAALRQ
CCCCCCHHHHHHHHHHCCCCEECCCCHHHHHHHHEEECCCCCCHHHHHCCHHHHHHHHCC
>Mature Secondary Structure
MIEKEAPEEYGYDRIRYNLSESSIADQKLSDIGLSLPDLTLFYGEHRGDKELRVLIAAQD
CCCCCCCHHCCCCCEEEECCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEEEECC
AGVSPDDVLVTAGAAGALFIISTSLLSASDHLVVIRPNYATNIETPRAIGCAISFVDLAF
CCCCCCCEEEECCCCCEEEEEEHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHEEHHHC
EDGFAIDVQAIKAAMRPNTKLISVTCPHNPTGTMMSRPDLDALVVLAESRNCLLLVDETY
CCCCEEEHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCHH
RDLSYGKRLPSAASLSPRAISVSSLSKAFGIPGIRIGWLITRDADLQETFLAAKEQIGIC
HHHHHHHCCCCCCCCCCCEEEHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHCCCH
GSVIDEGIARGMLQRRDAFLAALLPEMAKRRDIVQAWIDREPLVDWVRPEGGVVGFPRLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCEEECCCCC
VEPGFDLDRFYVNLLENHGTYVGPGHWFEMEKRFFRVGFGWPTEAELQGGLDAISAALRQ
CCCCCCHHHHHHHHHHCCCCEECCCCHHHHHHHHEEECCCCCCHHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2513189; 11427726; 8026489; 3137225; 1954227 [H]