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The map label for this gene is exbB [H]

Identifier: 13473530

GI number: 13473530

Start: 3325326

End: 3326075

Strand: Reverse

Name: exbB [H]

Synonym: mll4168

Alternate gene names: 13473530

Gene position: 3326075-3325326 (Counterclockwise)

Preceding gene: 13473532

Following gene: 13473529

Centisome position: 47.27

GC content: 67.87

Gene sequence:

>750_bases
ATGGGAAATCGGCGGCCGCATTGGAGAAAGCCAATGGAGCTCAACCTGCCGCACGATCTGTCGCCATGGGGCATGTTCAT
AGCCGCCGACATCATCGTGAAGGCGGTGATGATCGGACTGGCCTTCGCCTCGCTCGTCACCTGGACGATATGGCTGGCCA
AATCGCTGGAGATTCTTGGCGGCAAGTTGCGTATCCGCCGCGCCGTTCGCGCGATCGGTGATGCCGCGACGCTGAAGCAG
GCGAGCCGCGCGCTCGGCCGCAGCGGCGGGCCCGGCGCGCTTCTGGTCAAGGCAGCGGAAGAAGAGACCGCACTCTCGGC
CGGCGCGCTCGACCATGTCGGCGGCGACGGGTTGAAGGAACGGGTCACCTCGCGCCTGTCGCGCATCGAGGCGGCGGCGT
CGCGGCGCATGTCACGCGGCACAGGCGTGCTGGCGACGATCGGCTCCACGGCGCCCTTCGTCGGCCTGTTCGGCACGGTC
TGGGGCATCATGAACGCCTTCATCGGCATTTCGCAGGCGCAGACCACCAATCTGGCAGTGGTCGCGCCGGGCATCGCCGA
GGCGCTGCTGGCCACGGCGATGGGCCTCGTCGCGGCAATTCCAGCAGTGGTGATCTACAATGTCTTCGCCCGCTCGATAG
CCGGCTACCGGCAGATCCTCGCCGATGCCTCGGCGGGCGTCGAGAGGCTGGTCAGCCGCGACCTGGATTTCCGCACGGTC
GCGCCGGCAACGGCGCTGGCGGCGGAGTAG

Upstream 100 bases:

>100_bases
GCTGTCCCAACGAAGTGTTGACTGTTGCAGTCATCTTCAATGTTGACTTGTATACTCATGTTTCATAATCAACCCTGACA
TCGGACAGCCGAGGCCAGAA

Downstream 100 bases:

>100_bases
CGACGCCATGGGAGGCCGAATCCGCCAAAGCATGGACGACGACCTCGAGGAGAGCCACGAGATCAACGTCACGCCCTTCA
TCGACGTCATCCTGGTGCTG

Product: exbB, uptake of enterochelin; tonB-dependent uptake of B colicins

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MGNRRPHWRKPMELNLPHDLSPWGMFIAADIIVKAVMIGLAFASLVTWTIWLAKSLEILGGKLRIRRAVRAIGDAATLKQ
ASRALGRSGGPGALLVKAAEEETALSAGALDHVGGDGLKERVTSRLSRIEAAASRRMSRGTGVLATIGSTAPFVGLFGTV
WGIMNAFIGISQAQTTNLAVVAPGIAEALLATAMGLVAAIPAVVIYNVFARSIAGYRQILADASAGVERLVSRDLDFRTV
APATALAAE

Sequences:

>Translated_249_residues
MGNRRPHWRKPMELNLPHDLSPWGMFIAADIIVKAVMIGLAFASLVTWTIWLAKSLEILGGKLRIRRAVRAIGDAATLKQ
ASRALGRSGGPGALLVKAAEEETALSAGALDHVGGDGLKERVTSRLSRIEAAASRRMSRGTGVLATIGSTAPFVGLFGTV
WGIMNAFIGISQAQTTNLAVVAPGIAEALLATAMGLVAAIPAVVIYNVFARSIAGYRQILADASAGVERLVSRDLDFRTV
APATALAAE
>Mature_248_residues
GNRRPHWRKPMELNLPHDLSPWGMFIAADIIVKAVMIGLAFASLVTWTIWLAKSLEILGGKLRIRRAVRAIGDAATLKQA
SRALGRSGGPGALLVKAAEEETALSAGALDHVGGDGLKERVTSRLSRIEAAASRRMSRGTGVLATIGSTAPFVGLFGTVW
GIMNAFIGISQAQTTNLAVVAPGIAEALLATAMGLVAAIPAVVIYNVFARSIAGYRQILADASAGVERLVSRDLDFRTVA
PATALAAE

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1789381, Length=230, Percent_Identity=56.0869565217391, Blast_Score=240, Evalue=6e-65,
Organism=Escherichia coli, GI1786958, Length=240, Percent_Identity=31.6666666666667, Blast_Score=89, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014164 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 26077; Mature: 25946

Theoretical pI: Translated: 11.23; Mature: 11.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNRRPHWRKPMELNLPHDLSPWGMFIAADIIVKAVMIGLAFASLVTWTIWLAKSLEILG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GKLRIRRAVRAIGDAATLKQASRALGRSGGPGALLVKAAEEETALSAGALDHVGGDGLKE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHCCHHHCCCCHHHH
RVTSRLSRIEAAASRRMSRGTGVLATIGSTAPFVGLFGTVWGIMNAFIGISQAQTTNLAV
HHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
VAPGIAEALLATAMGLVAAIPAVVIYNVFARSIAGYRQILADASAGVERLVSRDLDFRTV
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHC
APATALAAE
CCHHHHCCC
>Mature Secondary Structure 
GNRRPHWRKPMELNLPHDLSPWGMFIAADIIVKAVMIGLAFASLVTWTIWLAKSLEILG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GKLRIRRAVRAIGDAATLKQASRALGRSGGPGALLVKAAEEETALSAGALDHVGGDGLKE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHCCHHHCCCCHHHH
RVTSRLSRIEAAASRRMSRGTGVLATIGSTAPFVGLFGTVWGIMNAFIGISQAQTTNLAV
HHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEE
VAPGIAEALLATAMGLVAAIPAVVIYNVFARSIAGYRQILADASAGVERLVSRDLDFRTV
ECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHC
APATALAAE
CCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8437515 [H]