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The map label for this gene is xylH [H]

Identifier: 13472220

GI number: 13472220

Start: 1984790

End: 1985887

Strand: Direct

Name: xylH [H]

Synonym: mlr2441

Alternate gene names: 13472220

Gene position: 1984790-1985887 (Clockwise)

Preceding gene: 13472219

Following gene: 13472221

Centisome position: 28.21

GC content: 65.39

Gene sequence:

>1098_bases
ATGGTTTCAGAGATTCGCGACGAGCGGGTCCGGTCCGTTTCACGCCTGAGCCGCCTGCTAAGCAGGCCGGAGCTTGGCGC
GGCCGCCGGTACCGTGCTGGTCTTCGTGTTCTTCGCCATCACGGCGGGAAGCACGGGGCTGTTCAGTGCCAAGGGCATCG
TCAATTTCCTCGAAGTCTCGGCCCAGCTTGGCATTCTCGCCGCTCCCGTGGCCCTGCTGATGATCGCCGGCGAGTTTGAT
CTGTCGGTCGGCTCGATGATCGGCTTTGCCGGCATCCTCATCGCCATCCCTGCCGTATTCTGGGGCTGGCCGATCTGGCT
TTCGCTGCTGTTCACCTTCGCCGTCTGCGGCGGCATCGGCGCGCTGAACGGGCTCGCCGTCGTCAGGACCGGCCTGCCCT
CCTTCATCGTGACGCTCGGCAGCCTCTTCATGTTGCGCGGCCTCACGCTTGGCCTCACGCGCGGCATTTCAGGGCGGACC
CAGGTGTCGGGCGTGCACGAGCTGGCGCAGAACGATCCCCTCAACAGCCTGTTCTCTGGCCAGGTGTTCACCGGCCTGAT
CGCCTGGCTTGCCGACCTCGGCCTGATCGGCAAGCGGGCGGACGGAATGCCGTCGATATCAGGCATTCCGGTGTCGATCG
TGTGGTGGATCGTGCTGACACTGGCCTGCACCTGGCTCTTGACGCGCAGCCGCTTCGGCAACTGGATCTTCGCCGCCGGG
GGCGAAGCCAATGCCGCGCGCAATCTCGGCGTGCCGGTGGCGCGCACCAAGATCACGCTGTTCGTCATGACGGCGCTCGC
GGCGGCCCTGTTCGCGGCGATCCAGGTGCTGGTCACCGGCTCCGCCGACACGCTGCGCGGCACGCAGAAGGAATTCGAGG
CCATCATCGCCGTCGTCATCGGCGGCACGCTGCTGACCGGCGGCTATGGATCGGCCATCGGCGCCATGTTCGGCGCCCTG
ATCTTCGGCGTGGTGCAGATGGGCATCTTCTACACCGGCATCGACACCGACTGGTTCAAGCTGTTCATGGGCGCCATGAT
GGTCATCGCGGTGCTGTTCAACAGCTATGTGCGCAACCGCGCCATGAGGAGTCGGTAA

Upstream 100 bases:

>100_bases
GACACCGCCGCATCGGTCATCGAGCTGTCGAAACAAGGCAAGCGCTAACACTGGCGGCCGGGGTCCCGCCCCGGCCGCTT
CATTTTGAGGTAACGCAGCC

Downstream 100 bases:

>100_bases
TGGCCGAGCCCTATGTCGAACTGAAGTCGGTCAGCAAATATTTCGGCTCGGTCGTAGCGCTGAAGGACGTGTCCTTCGAT
GTCTGCCCTGGCGAGGTGCA

Product: permease protein of sugar ABC transporter

Products: ADP; phosphate; xylose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MVSEIRDERVRSVSRLSRLLSRPELGAAAGTVLVFVFFAITAGSTGLFSAKGIVNFLEVSAQLGILAAPVALLMIAGEFD
LSVGSMIGFAGILIAIPAVFWGWPIWLSLLFTFAVCGGIGALNGLAVVRTGLPSFIVTLGSLFMLRGLTLGLTRGISGRT
QVSGVHELAQNDPLNSLFSGQVFTGLIAWLADLGLIGKRADGMPSISGIPVSIVWWIVLTLACTWLLTRSRFGNWIFAAG
GEANAARNLGVPVARTKITLFVMTALAAALFAAIQVLVTGSADTLRGTQKEFEAIIAVVIGGTLLTGGYGSAIGAMFGAL
IFGVVQMGIFYTGIDTDWFKLFMGAMMVIAVLFNSYVRNRAMRSR

Sequences:

>Translated_365_residues
MVSEIRDERVRSVSRLSRLLSRPELGAAAGTVLVFVFFAITAGSTGLFSAKGIVNFLEVSAQLGILAAPVALLMIAGEFD
LSVGSMIGFAGILIAIPAVFWGWPIWLSLLFTFAVCGGIGALNGLAVVRTGLPSFIVTLGSLFMLRGLTLGLTRGISGRT
QVSGVHELAQNDPLNSLFSGQVFTGLIAWLADLGLIGKRADGMPSISGIPVSIVWWIVLTLACTWLLTRSRFGNWIFAAG
GEANAARNLGVPVARTKITLFVMTALAAALFAAIQVLVTGSADTLRGTQKEFEAIIAVVIGGTLLTGGYGSAIGAMFGAL
IFGVVQMGIFYTGIDTDWFKLFMGAMMVIAVLFNSYVRNRAMRSR
>Mature_365_residues
MVSEIRDERVRSVSRLSRLLSRPELGAAAGTVLVFVFFAITAGSTGLFSAKGIVNFLEVSAQLGILAAPVALLMIAGEFD
LSVGSMIGFAGILIAIPAVFWGWPIWLSLLFTFAVCGGIGALNGLAVVRTGLPSFIVTLGSLFMLRGLTLGLTRGISGRT
QVSGVHELAQNDPLNSLFSGQVFTGLIAWLADLGLIGKRADGMPSISGIPVSIVWWIVLTLACTWLLTRSRFGNWIFAAG
GEANAARNLGVPVARTKITLFVMTALAAALFAAIQVLVTGSADTLRGTQKEFEAIIAVVIGGTLLTGGYGSAIGAMFGAL
IFGVVQMGIFYTGIDTDWFKLFMGAMMVIAVLFNSYVRNRAMRSR

Specific function: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789992, Length=362, Percent_Identity=31.4917127071823, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1788896, Length=357, Percent_Identity=29.1316526610644, Blast_Score=111, Evalue=9e-26,
Organism=Escherichia coli, GI87082395, Length=305, Percent_Identity=29.1803278688525, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1790191, Length=343, Percent_Identity=29.1545189504373, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1787794, Length=301, Percent_Identity=28.2392026578073, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI145693152, Length=305, Percent_Identity=27.5409836065574, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790524, Length=292, Percent_Identity=29.4520547945205, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788471, Length=311, Percent_Identity=28.6173633440514, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 38537; Mature: 38537

Theoretical pI: Translated: 10.72; Mature: 10.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSEIRDERVRSVSRLSRLLSRPELGAAAGTVLVFVFFAITAGSTGLFSAKGIVNFLEVS
CCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
AQLGILAAPVALLMIAGEFDLSVGSMIGFAGILIAIPAVFWGWPIWLSLLFTFAVCGGIG
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALNGLAVVRTGLPSFIVTLGSLFMLRGLTLGLTRGISGRTQVSGVHELAQNDPLNSLFSG
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHH
QVFTGLIAWLADLGLIGKRADGMPSISGIPVSIVWWIVLTLACTWLLTRSRFGNWIFAAG
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
GEANAARNLGVPVARTKITLFVMTALAAALFAAIQVLVTGSADTLRGTQKEFEAIIAVVI
CCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHH
GGTLLTGGYGSAIGAMFGALIFGVVQMGIFYTGIDTDWFKLFMGAMMVIAVLFNSYVRNR
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AMRSR
HHCCC
>Mature Secondary Structure
MVSEIRDERVRSVSRLSRLLSRPELGAAAGTVLVFVFFAITAGSTGLFSAKGIVNFLEVS
CCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
AQLGILAAPVALLMIAGEFDLSVGSMIGFAGILIAIPAVFWGWPIWLSLLFTFAVCGGIG
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALNGLAVVRTGLPSFIVTLGSLFMLRGLTLGLTRGISGRTQVSGVHELAQNDPLNSLFSG
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHH
QVFTGLIAWLADLGLIGKRADGMPSISGIPVSIVWWIVLTLACTWLLTRSRFGNWIFAAG
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
GEANAARNLGVPVARTKITLFVMTALAAALFAAIQVLVTGSADTLRGTQKEFEAIIAVVI
CCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHH
GGTLLTGGYGSAIGAMFGALIFGVVQMGIFYTGIDTDWFKLFMGAMMVIAVLFNSYVRNR
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AMRSR
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; xylose [Periplasm]; H2O [C]

Specific reaction: ATP + xylose [Periplasm] + H2O = ADP + phosphate + xylose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]